Ligand baccatin III
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
Basic Ligand Information
Molecular Structure

C31H38O11
baccatin III
OVMSOCFBDVBLFW-VHLOTGQHSA-N
Show all BRENDA pathways known for baccatin III
Roles as Enzyme Ligand
In Vivo Substrate in Enzyme-catalyzed Reactions (1 result)
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
baccatin III + 3-amino-3-phenylpropanoyl-CoA = 3'-N-debenzoyl-2'-deoxytaxol + coenzyme A
-
In Vivo Product in Enzyme-catalyzed Reactions (1 result)
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
acetyl-CoA + 10-deacetylbaccatin III = CoA + baccatin III
-
Substrate in Enzyme-catalyzed Reactions (2 results)
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
baccatin III + 3-amino-3-phenylpropanoyl-CoA = 3'-N-debenzoyl-2'-deoxytaxol + coenzyme A
-
baccatin III + 3-phenylisoserinoyl-CoA = ? + coenzyme A
-
Product in Enzyme-catalyzed Reactions (4 results)
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
acetyl-CoA + 10-deacetylbaccatin III = CoA + baccatin III
-
acetyl-CoA + 4-deacetylbaccatin III = CoA + baccatin III
-
N-acetyl-D-glucosamine + 10-deacetylbaccatin III = D-glucosamine + baccatin III
-
vinyl acetate + 10-deacetylbaccatin III = vinyl alcohol + baccatin III
-
Enzyme Kinetic Parameters
KM Value (1 result)
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
0.0024
-
pH and temperature not specified in the publication
References & Links
Literature References (3)
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Molecular cloning of a 10-deacetylbaccatin III-10-O-acetyl transferase cDNA from Taxus and functional expression in Escherichia coli
2000
Walker.K.; Croteau, R.
Proc. Natl. Acad. Sci. USA
97
583-587
-
Acetyl CoA: 10-deacetylbaccatin-III-10-O-acetyltransferase activity in leaves and cell suspension cultures of Taxus cuspidata
1998
Pennington, J.J.; Fett-Neto, A.G.; Nicholson, S.A.; Kingston, D.G.I.; Dicosmo, F.
Phytochemistry
49
2261-2266
Molecular cloning and heterologous expression of the C-13 phenylpropanoid side chain-CoA acyltransferase that functions in Taxol biosynthesis
2002
Walker, K.; Fujisaki, S.; Long, R.; Croteau, R.
Proc. Natl. Acad. Sci. USA
99
12715-12720
Links to other databases for baccatin III