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Ligand reduced phenazine methosulfate

Basic Ligand Information

Molecular Structure

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Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (1 result)

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Show Natural Substrate (1 entry)

EC NUMBER

PROVEN IN VIVO REACTION

REACTION DIAGRAM

LITERATURE

ENZYME 3D STRUCTURE

1.14.99.67

(1R,2R)-(-)-2-(N-dichloroacetyl)-amino-1-(4-aminophenyl)-1,3-propanediol + reduced phenazine methosulfate + 2 O2 = chloramphenicol + phenazine methosulfate + 2 H2O

760212

-

In Vivo Product in Enzyme-catalyzed Reactions (1 result)

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Show Natural Product (1 entry)

EC NUMBER

PROVEN IN VIVO REACTION

REACTION DIAGRAM

LITERATURE

ENZYME 3D STRUCTURE

1.5.5.2

L-proline + oxidized phenazine methosulfate = (S)-1-pyrroline-5-carboxylate + reduced phenazine methosulfate

0

-

Substrate in Enzyme-catalyzed Reactions (15 results)

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Show Substrate (15 entries)

EC NUMBER

REACTION

REACTION DIAGRAM

LITERATURE

ENZYME 3D STRUCTURE

1.1.2.10

acetaldehyde + reduced phenazine methosulfate = ethanol + phenazine methosulfate

756794

-

1.1.2.10

formaldehyde + reduced phenazine methosulfate = methanol + phenazine methosulfate

756794, 742793

-

1.1.2.10

propionaldehyde + reduced phenazine methosulfate = 1-propanol + phenazine methosulfate

756794

-

1.1.2.10

3 entries

1.1.5.2

D-glucosamino-1,5-lactone + reduced phenazine methosulfate = D-glucosamine + reduced phenazine methosulfate

746918

-

1.1.5.5

acetaldehyde + reduced phenazine methosulfate = ethanol + phenazine methosulfate

740121

-

1.1.5.5

propionaldehyde + reduced phenazine methosulfate = 1-propanol + phenazine methosulfate

740121

-

1.14.99.67

(1R,2R)-(-)-2-(N-dichloroacetyl)-amino-1-(4-aminophenyl)-1,3-propanediol + reduced phenazine methosulfate + 2 O2 = chloramphenicol + phenazine methosulfate + 2 H2O

759395, 760212

-

1.14.99.67

4-aminobenzoate + reduced phenazine methosulfate + 2 O2 = 4-nitrobenzoate + phenazine methosulfate + 2 H2O

759395

-

1.14.99.67

4-aminophenol + reduced phenazine methosulfate + 2 O2 = 4-nitrophenol + phenazine methosulfate + 2 H2O

759395

-

1.14.99.67

L-4-aminophenylalanine + reduced phenazine methosulfate + 2 O2 = L-4-nitrophenylalanine + phenazine methosulfate + 2 H2O

759395

-

1.14.99.67

N-[(1R,2R)-1-(4-aminophenyl)-1,3-dihydroxypropan-2-yl]-2,2-dichloroacetamide + reduced phenazine methosulfate + 2 O2 = chloramphenicol + phenazine methosulfate + 2 H2O

759397

-

1.1.5.5

2 entries

1.14.99.67

5 entries

1.17.1.4

NADH + reduced phenazine methosulfate + cytochrome c = NAD+ + ?

644598

-

1.3.5.1

fumarate + reduced phenazine methosulfate = succinate + phenazine methosulfate

707545

-

1.7.2.1

nitrite + reduced phenazine methosulfate = NO + oxidized phenazine methosulfate

764943, 765354, 764656, 763797

-

1.7.2.5

nitric oxide + reduced phenazine methosulfate = nitrous oxide + oxidized phenazine methosulfate + H2O

699991

-

Product in Enzyme-catalyzed Reactions (202 results)

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Show Product (202 entries)

EC NUMBER

REACTION

REACTION DIAGRAM

LITERATURE

ENZYME 3D STRUCTURE

1.1.2.10

1-butanol + phenazine methosulfate = butyraldehyde + reduced phenazine methosulfate

0

-

1.1.2.10

1-hexanol + phenazine methosulfate = hexaldehyde + reduced phenazine methosulfate

0

-

1.1.2.10

1-propanol + phenazine methosulfate = propionaldehyde + reduced phenazine methosulfate

0

-

1.1.2.10

ethanol + phenazine methosulfate = acetaldehyde + reduced phenazine methosulfate

0

-

1.1.2.10

formaldehyde + phenazine methosulfate + ? = formate + reduced phenazine methosulfate + ?

0

-

1.1.2.10

methanol + phenazine methosulfate = formaldehyde + reduced phenazine methosulfate

0

-

1.1.2.11

2-deoxy-D-glucose + phenazine methosulfate = 2-deoxy-3-dehydro-D-glucose + reduced phenazine methosulfate

0

-

1.1.2.11

D-galactose + phenazine methosulfate = 3-dehydro-D-galactose + reduced phenazine methosulfate

0

-

1.1.2.11

D-glucose + phenazine methosulfate = 3-dehydro-D-gluose + reduced phenazine methosulfate

0

-

1.1.2.11

methyl alpha-D-glucoside + phenazine methosulfate = methyl alpha-D-3-oxoglucoside + reduced phenazine methosulfate

0

-

1.1.2.10

6 entries

1.1.2.11

4 entries

1.1.2.4

D-lactate + oxidized phenazine methosulfate = pyruvate + reduced phenazine methosulfate + H+

0

-

1.1.2.8

1,2-butanediol + phenazine methosulfate = ? + reduced phenazine methosulfate

0

-

1.1.2.8

1,2-cyclopentandiol + phenazine methosulfate = ? + reduced phenazine methosulfate

0

-

1.1.2.8

1,3-butanediol + phenazine methosulfate = ? + reduced phenazine methosulfate

0

-

1.1.2.8

1-butanol + phenazine methosulfate = butanal + reduced phenazine methosulfate

0

-

1.1.2.8

1-cyclohexylethanol + phenazine methosulfate = ? + reduced phenazine methosulfate

0

-

1.1.2.8

1-hexanol + phenazine methosulfate = hexanal + reduced phenazine methosulfate

0

-

1.1.2.8

1-octanol + phenazine methosulfate = octanal + reduced phenazine methosulfate

0

-

1.1.2.8

2,3-butanediol + phenazine methosulfate = ? + reduced phenazine methosulfate

0

-

1.1.2.8

2,4-pentanediol + phenazine methosulfate = ? + reduced phenazine methosulfate

0

-

1.1.2.8

2-butanol + phenazine methosulfate = ? + reduced phenazine methosulfate

0

-

1.1.2.8

2-butanol + phenazine methosulfate = butan-2-one + reduced phenazine methosulfate

0

-

1.1.2.8

2-hexanol + phenazine methosulfate = ? + reduced phenazine methosulfate

0

-

1.1.2.8

2-phenylethanol + phenazine methosulfate = phenylacetaldehyde + reduced phenazine methosulfate

0

-

1.1.2.8

acetaldehyde + phenazine methosulfate = ? + reduced phenazine methosulfate

0

-

1.1.2.8

butyraldehyde + phenazine methosulfate = ? + reduced phenazine methosulfate

0

-

1.1.2.8

cinnamyl alcohol + phenazine methosulfate = cinnamyl aldehyde + reduced phenazine methosulfate

0

-

1.1.2.8

cis-1,2-cyclohexanediol + phenazine methosulfate = ? + reduced phenazine methosulfate

0

-

1.1.2.8

cyclohexanol + phenazine methosulfate = ? + reduced phenazine methosulfate

0

-

1.1.2.8

D-arabinose + phenazine methosulfate = ? + reduced phenazine methosulfate

0

-

1.1.2.8

D-arabitol + phenazine methosulfate = ? + reduced phenazine methosulfate

0

-

1.1.2.8

D-galactose + phenazine methosulfate = ? + reduced phenazine methosulfate

0

-

1.1.2.8

D-gluconate + phenazine methosulfate = ? + reduced phenazine methosulfate

0

-

1.1.2.8

D-lyxose + phenazine methosulfate = ? + reduced phenazine methosulfate

0

-

1.1.2.8

D-mannitol + phenazine methosulfate = ? + reduced phenazine methosulfate

0

-

1.1.2.8

D-ribose + phenazine methosulfate = ? + reduced phenazine methosulfate

0

-

1.1.2.8

D-sorbitol + phenazine methosulfate = ? + reduced phenazine methosulfate

0

-

1.1.2.8

D-xylose + phenazine methosulfate = ? + reduced phenazine methosulfate

0

-

1.1.2.8

ethanol + phenazine methosulfate = acetaldehyde + reduced phenazine methosulfate

0

-

1.1.2.8

ethanolamine + phenazine methosulfate = ? + reduced phenazine methosulfate

0

-

1.1.2.8

farnesol + phenazine methosulfate = farnesal + reduced phenazine methosulfate

0

-

1.1.2.8

glyceraldehyde + phenazine methosulfate = ? + reduced phenazine methosulfate

0

-

1.1.2.8

glycerol + phenazine methosulfate = ? + reduced phenazine methosulfate

0

-

1.1.2.8

hexanal + phenazine methosulfate = ? + reduced phenazine methosulfate

0

-

1.1.2.8

isopropanol + phenazine methosulfate = ? + reduced phenazine methosulfate

0

-

1.1.2.8

L-arabinose + phenazine methosulfate = ? + reduced phenazine methosulfate

0

-

1.1.2.8

L-ribose + phenazine methosulfate = ? + reduced phenazine methosulfate

0

-

1.1.2.8

meso-erythritol + phenazine methosulfate = ? + reduced phenazine methosulfate

0

-

1.1.2.8

methanol + phenazine methosulfate = formaldehyde + reduced phenazine methosulfate

0

-

1.1.2.8

octanal + phenazine methosulfate = ? + reduced phenazine methosulfate

0

-

1.1.2.8

ribitol + phenazine methosulfate = ? + reduced phenazine methosulfate

0

-

1.1.2.8

threitol + phenazine methosulfate = ? + reduced phenazine methosulfate

0

-

1.1.2.8

trans-1,2-cyclohexanediol + phenazine methosulfate = ? + reduced phenazine methosulfate

0

-

1.1.2.8

42 entries

1.1.2.B5

L-fucose + phenazine methosulfate = 2-dehydro-L-fucose + reduced phenazine methosulfate

0

-

1.1.3.15

glycolate + phenazine methosulfate = glyoxylate + reduced phenazine methosulfate

0

-

1.1.3.15

L-lactate + phenazine methosulfate = ? + reduced phenazine methosulfate

0

-

1.1.3.15

2 entries

1.1.3.38

vanillyl alcohol + phenazine methosulfate = vanillin + reduced phenazine methosulfate

10666

-

1.1.5.12

(R)-lactate + oxidized phenazine methosulfate = pyruvate + reduced phenazine methosulfate

0

-

1.1.5.12

(R)-lactate + phenazine methosulfate = pyruvate + reduced phenazine methosulfate

0

-

1.1.5.12

2 entries

1.1.5.14

fructose + phenazine methosulfate = 5-dehydro-D-fructose + reduced phenazine methosulfate

0

-

1.1.5.2

2-deoxy-D-glucose + oxidized N-methylphenazonium methyl sulfate = 2-deoxy-D-glucono-1,5-lactone + reduced N-methylphenazonium methyl sulfate

0

-

1.1.5.2

D-fucose + oxidized N-methylphenazonium methyl sulfate = 6-deoxy-D-galactono-1,5-lactone + reduced N-methylphenazonium methyl sulfate

0

-

1.1.5.2

D-galactose + oxidized N-methylphenazonium methyl sulfate = D-galactono-1,5-lactone + reduced N-methylphenazonium methyl sulfate

0

-

1.1.5.2

D-glucose + oxidized N-methylphenazonium methyl sulfate = D-glucono-1,5-lactone + reduced N-methylphenazonium methyl sulfate

0

-

1.1.5.2

D-xylose + oxidized N-methylphenazonium methyl sulfate = D-xylono-1,5-lactone + reduced N-methylphenazonium methyl sulfate

0

-

1.1.5.2

L-arabinose + oxidized N-methylphenazonium methyl sulfate = L-arabino-1,5-lactone + reduced N-methylphenazonium methyl sulfate

0

-

1.1.5.2

2-deoxy-D-glucose + phenazine methosulfate = 2-deoxy-D-glucono-1,5-lactone + reduced phenazine methosulfate

0

-

1.1.5.2

alpha-D-lactose + phenazine methosulfate = alpha-D-lactono-1,5-lactone + reduced phenazine methosulfate

0

-

1.1.5.2

D-cellobiose + phenazine methosulfate = D-cellobiono-1,5-lactone + reduced phenazine methosulfate

0

-

1.1.5.2

D-galactose + phenazine methosulfate = D-galactono-1,5-lactone + reduced phenazine methosulfate

0

-

1.1.5.2

D-glucosamino-1,5-lactone + reduced phenazine methosulfate = D-glucosamine + reduced phenazine methosulfate

0

-

1.1.5.2

D-glucose + phenazine methosulfate = D-glucono-1,5-lactone + reduced phenazine methosulfate

0

-

1.1.5.2

D-glucose 6-phosphate + phenazine methosulfate = 6-phospho-D-glucono-1,5-lactone + reduced phenazine methosulfate

0

-

1.1.5.2

D-mannose + phenazine methosulfate = D-mannono-1,5-lactone + reduced phenazine methosulfate

0

-

1.1.5.2

D-ribose + phenazine methosulfate = D-ribono-1,4-lactone + reduced phenazine methosulfate

0

-

1.1.5.2

D-xylose + phenazine methosulfate = D-xylono-1,5-lactone + reduced phenazine methosulfate

0

-

1.1.5.2

ethanol + phenazine methosulfate = acetaldehyde + reduced phenazine methosulfate

0

-

1.1.5.2

L-arabinose + phenazine methosulfate = D-arabinono-1,5-lactone + reduced phenazine methosulfate

0

-

1.1.5.2

maltose + phenazine methosulfate = D-maltono-1,5-lactone + reduced phenazine methosulfate

0

-

1.1.5.2

maltotriose + phenazine methosulfate = D-maltotriono-1,5-lactone + reduced phenazine methosulfate

0

-

1.1.5.2

methanol + phenazine methosulfate = formaldehyde + reduced phenazine methosulfate

0

-

1.1.5.2

21 entries

1.1.5.3

sn-glycerol 3-phosphate + phenazine methosulfate = glycerone phosphate + reduced phenazine methosulfate

0

-

1.1.5.5

1-propanol + phenazine methosulfate = propionaldehyde + reduced phenazine methosulfate

0

-

1.1.5.5

5-(hydroxymethyl)furfural + phenazine methosulfate = ? + reduced phenazine methosulfate

0

-

1.1.5.5

5-(hydroxymethyl)furoic acid + phenazine methosulfate = ? + reduced phenazine methosulfate

0

-

1.1.5.5

5-formylfurfural + phenazine methosulfate = ? + reduced phenazine methosulfate

0

-

1.1.5.5

ethanol + phenazine methosulfate = acetaldehyde + reduced phenazine methosulfate

0

-

1.1.5.5

methanol + phenazine methosulfate = formaldehyde + reduced phenazine methosulfate

0

-

1.1.5.8

quinate + phenazine methosulfate = 3-dehydroquinate + reduced phenazine methosulfate

0

-

1.1.5.8

shikimate + phenazine methosulfate = 3-dehydroshikimate + reduced phenazine methosulfate

0

-

1.1.5.5

6 entries

1.1.5.8

2 entries

1.1.5.9

D-glucose + phenazine methosulfate = D-glucono-1,5-lactone + reduced phenazine methosulfate

0

-

1.1.99.1

choline + phenazine methosulfate = betaine aldehyde + reduced phenazine methosulfate

0

-

1.1.99.22

glycerol + phenazine methosulfate = glycerone + reduced phenazine methosulfate

0

-

1.1.99.27

(R)-Pantolactone + phenazine methosulfate = 2-Dehydropantonolactone + reduced phenazine methosulfate

0

-

1.1.99.32

L-sorbose + phenazine methosulfate = L-sorbosone + reduced phenazine methosulfate

0

-

1.1.99.35

D-galactose + oxidized N-methylphenazonium methyl sulfate = D-galactono-1,5-lactone + reduced N-methylphenazonium methyl sulfate

0

-

1.1.99.35

D-glucose + oxidized N-methylphenazonium methyl sulfate = D-glucono-1,5-lactone + reduced N-methylphenazonium methyl sulfate

0

-

1.1.99.35

D-xylose + oxidized N-methylphenazonium methyl sulfate = D-xylono-1,5-lactone + reduced N-methylphenazonium methyl sulfate

0

-

1.1.99.35

lactose + oxidized N-methylphenazonium methyl sulfate = 4-O-beta-D-galactopyranosyl-D-glucono-1,5-lactone + reduced N-methylphenazonium methyl sulfate

0

-

1.1.99.35

D-glucose + phenazine methosulfate = D-glucono-1,5-lactone + reduced phenazine methosulfate

0

-

1.1.99.39

(R)-2-hydroxyglutarate + phenazine methosulfate = 2-oxoglutarate + reduced phenazine methosulfate

0

-

1.1.99.39

D-malate + phenazine methosulfate = ? + reduced phenazine methosulfate

0

-

1.1.99.39

(R)-2-hydroxyglutarate + phenazinemethosulfate = 2-oxoglutarate + reduced phenazinemethosulfate

0

-

1.1.99.35

5 entries

1.1.99.39

3 entries

1.1.99.42

4-pyridoxate + phenazine methosulfate = 5-formyl-3-hydroxy-2-methylpyridine-4-carboxylate + reduced phenazine methosulfate

0

-

1.12.99.6

H2 + oxidized phenazine methosulfate = reduced phenazine methosulfate + H+

0

-

1.12.99.6

H2 + phenazine methosulfate = H+ + reduced phenazine methosulfate

0

-

1.13.12.2

alanine + propylamine + phenazine methosulfate = pyruvate + NH3 + reduced phenazine methosulfate

440265

-

1.13.12.2

L-arginine + phenazine methosulfate = 2-keto-5-guanidinovalerate + NH3 + reduced phenazine methosulfate

440265

-

1.13.12.2

L-lysine + phenazine methosulfate = 2-keto-6-amino-n-hexanoate + NH3 + reduced phenazine methosulfate

440265

-

1.13.12.2

L-ornithine + phenazine methosulfate = 2-keto-5-aminopentanoate + NH3 + reduced phenazine methosulfate

440265

-

1.12.99.6

2 entries

1.13.12.2

4 entries

1.17.1.5

nicotinate + H2O + phenazine methosulfate = 6-hydroxynicotinate + reduced phenazine methosulfate

0

-

1.17.1.9

formate + phenazine methosulfate = CO2 + reduced phenazine methosulfate

0

-

1.17.9.1

2,4-xylenol + phenazine methosulfate + H2O = 4-hydroxy-3-methylbenzaldehyde + reduced phenazine methosulfate + H+

0

-

1.17.9.1

4-cresol + phenazine methosulfate + H2O = 4-hydroxybenzyl alcohol + reduced phenazine methosulfate

0

-

1.17.9.1

4-methylphenol + phenazine methosulfate + H2O = 4-hydroxybenzaldehyde + reduced phenazine methosulfate + H+

0

-

1.17.9.1

3 entries

1.17.99.2

ethylbenzene + H2O + phenazine methosulfate = (S)-1-phenylethanol + reduced phenazine methosulfate

0

-

1.2.5.2

acetaldehyde + oxidized phenazine methosulfate = acetic acid + reduced phenazine methosulfate

0

-

1.2.5.2

acetaldehyde + phenazine methosulfate = acetate + reduced phenazine methosulfate

0

-

1.2.5.2

glutaraldehyde + oxidized phenazine methosulfate = glutaric acid + reduced phenazine methosulfate

0

-

1.2.5.2

propanal + oxidized phenazine methosulfate = propanoic acid + reduced phenazine methosulfate

0

-

1.2.7.4

CO + H2O + oxidized phenazine methosulfate = CO2 + reduced phenazine methosulfate

0

-

1.2.7.4

CO + H2O + phenazine methosulfate = CO2 + reduced phenazine methosulfate

390449

-

1.2.5.2

4 entries

1.2.7.4

2 entries

1.3.2.3

L-galactono-1,4-lactone + phenazine methosulfate = L-ascorbate + reduced phenazine methosulfate

0

-

1.3.5.1

succinate + oxidized phenazine methosulfate = fumarate + reduced phenazine methosulfate

0

-

1.3.5.1

succinate + phenazine methosulfate = fumarate + reduced phenazine methosulfate

0

-

1.3.5.1

2 entries

1.3.8.4

isovaleryl-CoA + phenazine methosulfate = 3-methylcrotonyl-CoA + reduced phenazine methosulfate

0

-

1.3.8.6

glutaryl-CoA + phenazine methosulfate = crotonyl-CoA + CO2 + reduced phenazine methosulfate

0

-

1.3.8.8

arachidonoyl-CoA + phenazine methosulfate = (2E,5Z,8Z,11Z,14Z)-2,5,8,11,14-eicosapentaenoyl-CoA + reduced phenazine methosulfate

391272

-

1.3.8.8

butyryl-CoA + phenazine methosulfate = 2-butenoyl-CoA + reduced phenazine methosulfate

391282

-

1.3.8.8

decanoyl-CoA + phenazine methosulfate = (2E)-2-decenoyl-CoA + reduced phenazine methosulfate

394661, 394662, 391047, 391203, 391272, 391282, 394642, 394667, 391268

-

1.3.8.8

docosanoyl-CoA + phenazine methosulfate = 2-docosenoyl-CoA + reduced phenazine methosulfate

391272, 391282

-

1.3.8.8

dodecanoyl-CoA + phenazine methosulfate = (2E)-2-dodecenoyl-CoA + reduced phenazine methosulfate

394662, 391047, 391203, 391272, 391282, 394642, 394667, 391268

-

1.3.8.8

eicosanoyl-CoA + phenazine methosulfate = trans-2-eicosenoyl-CoA + reduced phenazine methosulfate

391203, 391272, 391282

-

1.3.8.8

erucoyl-CoA + phenazine methosulfate = (2E,13Z)-2,13-docosadienoyl-CoA + reduced phenazine methosulfate

391272

-

1.3.8.8

hexanoyl-CoA + phenazine methosulfate = 2-hexenoyl-CoA + reduced phenazine methosulfate

391282, 394667, 391268

-

1.3.8.8

linolenoyl-CoA + phenazine methosulfate = (2E,6Z,9Z,12Z)2,6,9,12-octadecatetraenoyl-CoA + reduced phenazine methosulfate

391272

-

1.3.8.8

linoleoyl-CoA + phenazine methosulfate = (2E,9Z,12Z)-2,9,12-octadecatrienoyl-CoA + reduced phenazine methosulfate

391272

-

1.3.8.8

octanoyl-CoA + phenazine methosulfate = 2-octenoyl-CoA + reduced phenazine methosulfate

394661, 391203, 391272, 391282, 394642, 394667, 391268

-

1.3.8.8

oleoyl-CoA + phenazine methosulfate = (2E,9Z)-2,9-octadecadienoyl-CoA + reduced phenazine methosulfate

391272

-

1.3.8.8

omega-phenyldecanoyl-CoA + phenazine methosulfate = 10-phenyl-2-decenoyl-CoA + reduced phenazine methosulfate

394642

-

1.3.8.8

omega-phenyldodecanoyl-CoA + phenazine methosulfate = 12-phenyl-2-dodecenoyl-CoA + reduced phenazine methosulfate

394642

-

1.3.8.8

palmitoleoyl-CoA + phenazine methosulfate = (2E,9Z)-2,9-hexadecadienoyl-CoA + reduced phenazine methosulfate

391272

-

1.3.8.8

palmitoyl-CoA + phenazine methosulfate = 2-hexadecenoyl-CoA + reduced phenazine methosulfate

394661, 391047, 391203, 391270, 391272, 391282, 394653, 394667, 391268

-

1.3.8.8

stearoyl-CoA + phenazine methosulfate = 2-octadecenoyl-CoA + reduced phenazine methosulfate

391047, 391203, 391272, 391282, 394667, 391268

-

1.3.8.8

tetradecanoyl-CoA + phenazine methosulfate = 2-tetradecenoyl-CoA + reduced phenazine methosulfate

394662, 391047, 391203, 391272, 391282, 394667, 391268

-

1.3.99.4

11beta,17alpha,21-trihydroxypregn-4-ene-3,20-dione + phenazine methosulfate = 1,4-pregnene-17alpha,21-diol-3,11,20-trione + reduced phenazine methosulfate

0

-

1.3.99.4

4-androstene-3,17-dione + phenazine methosulfate = 1,4-androstadiene-3,17-dione + reduced phenazine methosulfate

0

-

1.3.99.4

4-androstene-3,17-dione + phenazine methosulfate = 1,4-androstene-3,17-dione + reduced phenazine methosulfate

0

-

1.3.99.5

1-androstene-3,17-dione + phenazine methosulfate = 1,4-androstadiene-3,17-dione + reduced phenazine methosulfate

0

-

1.3.99.5

1-estrene-3,17-dione + phenazine methosulfate = 1,4-estradiene-3,17-dione + reduced phenazine methosulfate

0

-

1.3.99.6

3,12-dioxo-5beta-cholan-24-oic acid methyl ester + phenazine methosulfate = 3,12-dioxo-4-cholen-24 oic acid methyl ester + reduced phenazine methosulfate

0

-

1.3.99.6

3-oxo-5beta-24-cholan-oic acid + phenazine methosulfate = 3-oxo-4-cholen-24-oic acid + reduced phenazine methosulfate

0

-

1.4.99.2

hypotaurine + H2O + phenazine methosulfate = ? + NH3 + reduced phenazine methosulfate

395284, 395285

-

1.4.99.2

taurine + H2O + phenazine methosulfate = sulfoacetaldehyde + NH3 + reduced phenazine methosulfate

395284, 395285

-

1.4.99.6

D-alanine + phenazine methosulfate + H2O = pyruvate + NH3 + reduced phenazine methosulfate

0

-

1.4.99.6

D-arginine + phenazine methosulfate + H2O = 5-guanidino-2-oxopentanoate + NH3 + reduced phenazine methosulfate

0

-

1.4.99.6

D-arginine + phenazine methosulfate = 5-guanidino-2-oxopentanoate + NH3 + reduced phenazine methosulfate

0

-

1.4.99.6

D-asparagine + phenazine methosulfate + H2O = 2-oxobutanedioate + NH3 + reduced phenazine methosulfate

0

-

1.4.99.6

D-glutamine + phenazine methosulfate + H2O = 5-amino-2,5-dioxopentanoate + NH3 + reduced phenazine methosulfate

0

-

1.4.99.6

D-histidine + phenazine methosulfate + H2O = 3-(1H-imidazol-4-yl)-2-oxopropanoate + NH3 + reduced phenazine methosulfate

0

-

1.4.99.6

D-histidine + phenazine methosulfate = 3-(1H-imidazol-4-yl)-2-oxopropanoate + NH3 + reduced phenazine methosulfate

0

-

1.4.99.6

D-isoleucine + phenazine methosulfate + H2O = 3-methyl-2-oxopentanoate + NH3 + reduced phenazine methosulfate

0

-

1.4.99.6

D-leucine + phenazine methosulfate + H2O = 4-methyl-2-oxopentanoate + NH3 + reduced phenazine methosulfate

0

-

1.4.99.6

D-leucine + phenazine methosulfate = ? + NH3 + reduced phenazine methosulfate

0

-

1.4.99.6

D-lysine + phenazine methosulfate + H2O = 7-amino-2-oxoheptanoic acid + NH3 + reduced phenazine methosulfate

0

-

1.4.99.6

D-lysine + phenazine methosulfate = 6-amino-2-oxohexanoate + NH3 + reduced phenazine methosulfate

0

-

1.4.99.6

D-methionine + phenazine methosulfate + H2O = 4-methylsulfanyl-2-oxobutanoate + NH3 + reduced phenazine methosulfate

0

-

1.4.99.6

D-methionine + phenazine methosulfate = 4-methylsulfanyl-2-oxobutanoate + NH3 + reduced phenazine methosulfate

0

-

1.4.99.6

D-phenylalanine + phenazine methosulfate + H2O = 2-oxo-3-phenylpropanoate + NH3 + reduced phenazine methosulfate

0

-

1.4.99.6

D-phenylalanine + phenazine methosulfate = 2-oxo-3-phenylpropanoate + NH3 + reduced phenazine methosulfate

0

-

1.4.99.6

D-proline + phenazine methosulfate + H2O = DELTA1-pyrroline-2-carboxylate + NH3 + reduced phenazine methosulfate

0

-

1.4.99.6

D-serine + phenazine methosulfate + H2O = 3-hydroxy-2-oxopropanoate + NH3 + reduced phenazine methosulfate

0

-

1.4.99.6

D-threonine + phenazine methosulfate + H2O = 3-hydroxy-2-oxobutanoate + NH3 + reduced phenazine methosulfate

0

-

1.4.99.6

D-tryptophan + phenazine methosulfate + H2O = 3-indole-2-oxopropanoate + NH3 + reduced phenazine methosulfate

0

-

1.4.99.6

D-tyrosine + phenazine methosulfate + H2O = (4-hydroxyphenyl)pyruvate + NH3 + reduced phenazine methosulfate

0

-

1.4.99.6

D-tyrosine + phenazine methosulfate = 3-(4-hydroxyphenyl)-2-oxopropanoate + NH3 + reduced phenazine methosulfate

0

-

1.4.99.6

D-valine + phenazine methosulfate + H2O = 2-oxopentanoate + NH3 + reduced phenazine methosulfate

0

-

1.3.8.8

18 entries

1.3.99.4

3 entries

1.3.99.5

2 entries

1.3.99.6

2 entries

1.4.99.2

2 entries

1.4.99.6

23 entries

1.5.3.1

sarcosine + H2O + phenazine methosulfate = glycine + formaldehyde + reduced phenazine methosulfate

0

-

1.5.5.2

L-proline + oxidized phenazine methosulfate = (S)-1-pyrroline-5-carboxylate + reduced phenazine methosulfate

0

-

1.5.8.1

dimethylamine + H2O + phenazine methosulfate = methylamine + formaldehyde + reduced phenazine methosulfate

0

-

1.5.8.2

2-aminoethyldimethylamine + H2O + phenazine methosulfate = ? + reduced phenazine methosulfate

393923

-

1.5.8.2

2-chloroethyldimethylamine + H2O + phenazine methosulfate = ? + reduced phenazine methosulfate

393923

-

1.5.8.2

2-hydroxyethyldimethylamine + H2O + phenazine methosulfate = ? + reduced phenazine methosulfate

393923

-

1.5.8.2

diethylamine + H2O + phenazine methosulfate = ethylamine + acetaldehyde + reduced phenazine methosulfate

393920, 393923

-

1.5.8.2

diethylmethylamine + H2O + phenazine methosulfate = diethylamine + ethylmethylamine + formaldehyde + acetaldehyde + reduced phenazine methosulfate

393923

-

1.5.8.2

ethyldimethylamine + H2O + phenazine methosulfate = ethylmethylamine + formaldehyde + reduced phenazine methosulfate

393923

-

1.5.8.2

triethylamine + H2O + phenazine methosulfate = diethylamine + acetaldehyde + reduced phenazine methosulfate

393923

-

1.5.8.2

trimethylamine + H2O + phenazine methosulfate = dimethylamine + formaldehyde + reduced phenazine methosulfate

393892, 393911, 393920, 393923, 393924, 393922, 393900

-

1.5.8.2

8 entries

1.5.8.3

sarcosine + H2O + phenazine methosulfate = glycine + formaldehyde + reduced phenazine methosulfate

0

-

1.5.99.13

D-proline + oxidized phenazine methosulfate = DELTA1-pyrroline 2-carboxylate + reduced phenazine methosulfate

0

-

1.5.99.14

1-(6-hydroxypyridin-3-yl)-4-(methylamino)butan-1-one + phenazine methosulfate + H2O = 1-(2,6-dihydroxypyridin-3-yl)-4-(methylamino)butan-1-one + reduced phenazine methosulfate

0

-

1.5.99.5

N-methylglutamate + phenazine methosulfate + H2O = L-glutamate + formaldehyde + reduced phenazine methosulfate

0

-

1.5.99.6

spermidine + phenazine methosulfate = 1,3-diaminopropane + 4-aminobutyraldehyde + reduced phenazine methosulfate

0

-

1.5.99.6

spermidine + phenazine methosulfate = 1,3-diaminopropane + DELTA1-pyrroline + reduced phenazine methosulfate

0

-

1.5.99.6

spermine + phenazine methosulfate = spermidine + 3-aminopropionaldehyde + reduced phenazine methosulfate

0

-

1.5.99.6

3 entries

1.5.99.B2

L-proline + oxidized phenazine methosulfate = (S)-1-pyrroline-5-carboxylate + reduced phenazine methosulfate

0

-

1.7.2.1

nitric oxide + H2O + oxidized phenazine methosulfate = nitrite + reduced phenazine methosulfate + 2 H+

0

-

1.7.2.5

N2O + phenazine methosulfate + H2O = NO + reduced phenazine methosulfate

0

-

1.7.2.6

hydrazine + phenazine methosulfate = N2 + reduced phenazine methosulfate

394326

-

1.7.2.6

hydroxylamine + H2O + phenazine methosulfate = nitric oxide + reduced phenazine methosulfate + H+

0

-

1.7.2.8

hydrazine + phenazine methosulfate = ? + reduced phenazine methosulfate

0

-

1.7.2.8

hydroxylamine + NH3 + phenazine methosulfate = NO2 + H2O + reduced phenazine methosulfate

0

-

1.7.2.6

2 entries

1.7.2.8

2 entries

Enzyme Kinetic Parameters

References & Links

Literature References (38)

top print hide

Show Reference (38 entries)

BRENDA REFERENCE ID

PUBMED ID

TITLE

YEAR

AUTHORS

JOURNAL

VOLUME

PAGES

10666

1396672

Purification and characterization of vanillyl-alcohol oxidase from Penicillium simplicissimum. A novel aromatic alcohol oxidase containing covalently bound FAD

1992

De Jong, E.; van Berkel, W.J.H.; van der Zwan, R.P.; de Bont, J.A.M.

Eur. J. Biochem.

208

651-657

390449

3818661

Carbon monoxide dehydrogenase from Methanosarcina barkeri. Disaggregation, purification, and physicochemical properties of the enzyme

1987

Grahame, D.A.; Stadtman, T.C.

J. Biol. Chem.

262

3706-3712

391047

2914148

Compartmentation of dicarboxylic acid beta-oxidation in rat liver: importance of peroxisomes in the metabolism of dicarboxylic acids

1989

Suzuki, H.; Yamada, J.; Watanabe, T.; Suga, T.

Biochim. Biophys. Acta

990

25-30

391203

6401712

Separation and properties of five distinct acyl-CoA dehydrogenases from rat liver mitochondria. Identification of a new 2-methyl branched chain acyl-CoA dehydrogenase

1983

Ikeda, Y.; Dabrowski, C.; Tanaka, K.

J. Biol. Chem.

258

1066-1076

391268

4084576

Spectroscopic analysis of the interaction of rat liver short-chain, medium-chain, and long-chain acyl coenzyme A dehydrogenases with acyl coenzyme A substrates

1985

Ikeda, Y.; Okamura-Ikeda, K.; Tanaka, K.

Biochemistry

24

7192-7199

391270

3968065

An essential cysteine residue located in the vicinity of the FAD-binding site in short-chain, medium-chain, and long-chain acyl-CoA dehydrogenases from rat liver mitochondria

1985

Okamura-Ikeda, K.; Ikeda, Y.; Tanaka, K.

J. Biol. Chem.

260

1338-1345

391272

3968063

Purification and characterization of short-chain, medium-chain, and long-chain acyl-CoA dehydrogenases from rat liver mitochondria. Isolation of the holo- and apoenzymes and conversion of the apoenzyme to the holoenzyme

1985

Ikeda, Y.; Okamura-Ikeda, K.; Tanaka, K.

J. Biol. Chem.

260

1311-1325

391282

7334008

Purification and properties of rat liver acyl-CoA dehydrogenases and electron transfer flavoprotein

1981

Furuta, S.; Miyazawa, S.; Hashimoto, T.

J. Biochem.

90

1739-1750

393892

9725623

Probing the stabilizing role of C-terminal residues in trimethylamine dehydrogenase

1998

Ertrughrul, O.W.D.; Errington, N.; Raza, S.; Sutcliffe, M.J.; Rowe, A.J.; Scrutton, N.S.

Protein Eng.

11

447-455

393900

3223938

Microcoulometric analysis of trimethylamine dehydrogenase

1988

Barber, M.J.; Pollock, V.; Spence, J.T.

Biochem. J.

256

657-659

393911

7169636

Crystallographic study of the iron-sulfur flavoprotein trimethylamine dehydrogenase from the bacterium W3A1

1982

Lim, L.W.; Mathews, F.S.

J. Mol. Biol.

162

869-876

393920

-

Trimethylamine dehydrogenase from a methylotrophic bacterium. I. Isolation and steady-state kinetics

1976

Steenkamp, D.J.; Mallinson, J.

Biochim. Biophys. Acta

429

7005-719

393922

1137092

An enzymatic method for the microestimation of trimethylamine

1975

Large, P.J.; McDougall, H.

Anal. Biochem.

64(1)

304-310

393923

4462741

Purification and properties of the trimethylamine dehydrogenase of bacterium 4B6

1974

Colby, J.; Zatman, L.J.

Biochem. J.

143

555-567

393924

4722893

Trimethylamine metabolism in obligate and facultative methylotrophs

1973

Colby, J.; Zatman, L.J.

Biochem. J.

132

101-112

394326

199251

Hydroxylamine oxidoreductase of Nitrosomonas. Oxidation of diethyldithiocarbamate concomitant with stimulation of nitrite synthesis

1977

Hooper, A.B.; Terry, K.R.; Maxwell, P.C.

Biochim. Biophys. Acta

462

141-152

394642

3651489

Participation of peroxisomes in the metabolism of xenobiotic acyl compounds: comparison between peroxisomal and mitochondrial beta-oxidation of omega-phenyl fatty acids in rat liver

1987

Yamada, J.; Ogawa, S.; Horie, S.; Watanabe, T.; Suga, T.

Biochim. Biophys. Acta

921

292-301

394653

7334009

Induction of acyl-CoA dehydrogenases and electron transfer flavoprotein and their roles in fatty acid oxidation in rat liver mitochondria

1981

Furuta, S.; Miyazawa, S.; Hashimoto, T.

J. Biochem.

90

1751-1756

394661

8155643

Identification of the catalytic base in long chain acyl-CoA dehydrogenase

1994

Djordjevic, S.; Dong, Y.; Paschke, R.; Frerman, F.E.; Strauss, A.W.; Kim, J.J.

Biochemistry

33

4258-4264

394662

7769092

Purification of human very-long-chain acyl-coenzyme A dehydrogenase and characterization of its deficiency in seven patients

1995

Aoyama, T.; Souri, M.; Ushikubo, S.; Kamijo, T.; Yamaguchi, S.; Kelley, R.I.; Rhead, W.J.; Uetake, K.; Tanaka, K.; Hashimoto, T.

J. Clin. Invest.

95

2465-2473

394667

10198089

Identification, separation, and characterization of acyl-coenzyme A dehydrogenases involved in mitochondrial beta-oxidation in higher plants

1999

Bode, K.; Hooks, M.A.; Couee, I.

Plant Physiol.

119

1305-1314

395284

3657561

Taurine dehydrogenase

1987

Kondo, H.; Ishimoto, M.

Methods Enzymol.

143

496-499

395285

4724302

Purification and some properties of taurine dehydrogenase from a bacterium

1973

Kondo, H.; Kagotani, K.; Oshima, M.; Ishimoto, M.

J. Biochem.

73

1269-1278

440265

818961

A dehydrogenase reaction catalyzed by lysine monooxygenase, a flavooxygenase

1976

Maruyama, K.; Yamauchi, T.; Yamamoto, S.; Hayaishi, O.

Arch. Biochem. Biophys.

173

480-489

644598

1313286

Xanthine dehydrogenase from Drosophila melanogaster: Purification and properties of the wild-type enzyme and of a variant lacking iron-sulfur centers

1992

Hughes, R.K.; Bennett, B.; Bray, R.C.

Biochemistry

31

3073-3083

699991

18433624

The respiratory nitric oxide reductase (NorBC) from Paracoccus denitrificans

2008

Field, S.J.; Thorndycroft, F.H.; Matorin, A.D.; Richardson, D.J.; Watmough, N.J.

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437

79-101

707545

19103151

Purification, characterization and crystallization of menaquinol:fumarate oxidoreductase from the green filamentous photosynthetic bacterium Chloroflexus aurantiacus

2009

Xin, Y.; Lu, Y.K.; Fromme, R.; Fromme, P.; Blankenship, R.E.

Biochim. Biophys. Acta

1787

86-96

740121

24036413

The two-step electrochemical oxidation of alcohols using a novel recombinant PQQ alcohol dehydrogenase as a catalyst for a bioanode

2013

Takeda, K.; Matsumura, H.; Ishida, T.; Samejima, M.; Igarashi, K.; Nakamura, N.; Ohno, H.

Bioelectrochemistry

94

75-78

742793

27573017

Pyrroloquinoline quinone ethanol dehydrogenase in Methylobacterium extorquens AM1 extends lanthanide-dependent metabolism to multicarbon substrates

2016

Good, N.M.; Vu, H.N.; Suriano, C.J.; Subuyuj, G.A.; Skovran, E.; Martinez-Gomez, N.C.

J. Bacteriol.

198

3109-3118

746918

27592307

Biochemical and structural characterization of quinoprotein aldose sugar dehydrogenase from Thermus thermophilus HJ6 Mutational analysis of Tyr156 in the substrate-binding site

2016

Kim, H.; Wang, J.; Lee, J.; Park, A.; Park, H.; Jeon, S.

Arch. Biochem. Biophys.

608

20-26

756794

29997591

Lanthanide-dependent methanol dehydrogenases of XoxF4 and XoxF5 clades are differentially distributed among methylotrophic bacteria and they reveal different biochemical properties

2018

Huang, J.; Yu, Z.; Chistoserdova, L.

Front. Microbiol.

9

1366

759395

25564306

An unusual peroxo intermediate of the arylamine oxygenase of the chloramphenicol biosynthetic pathway

2015

Makris, T.; Vu, V.; Meier, K.; Komor, A.; Rivard, B.; Muenck, E.; Que, L.; Lipscomb, J.

J. Am. Chem. Soc.

137

1608-1617

759397

27203126

Mechanism for six-electron aryl-N-oxygenation by the non-heme diiron enzyme CmlI

2016

Komor, A.; Rivard, B.; Fan, R.; Guo, Y.; Que, L.; Lipscomb, J.

J. Am. Chem. Soc.

138

7411-7421

760212

24347692

CmlI is an N-oxygenase in the biosynthesis of chloramphenicol

2012

Lu, H.; Chanco, E.; Zhao, H.

Tetrahedron

68

7651-7654

763797

32051772

Unexpected roles of a tether harboring a tyrosine gatekeeper residue in modular nitrite reductase catalysis

2019

Hedison, T.M.; Shenoy, R.T.; Iorgu, A.I.; Heyes, D.J.; Fisher, K.; Wright, G.S.A.; Hay, S.; Eady, R.R.; Antonyuk, S.V.; Hasnain, S.S.; Scrutton, N.S.

ACS Catal.

9

6087-6099

764656

32255260

Reverse protein engineering of a novel 4-domain copper nitrite reductase reveals functional regulation by protein-protein interaction

2021

Sasaki, D.; Watanabe, T.F.; Eady, R.R.; Garratt, R.C.; Antonyuk, S.V.; Hasnain, S.S.

FEBS J.

288

262-280

764943

32431838

Structures of substrate- and product-bound forms of a multi-domain copper nitrite reductase shed light on the role of domain tethering in protein complexes

2020

Sasaki, D.; Watanabe, T.F.; Eady, R.R.; Garratt, R.C.; Antonyuk, S.V.; Hasnain, S.S.

IUCrJ

7

557-565

765354

30318500

Nitric oxide production from nitrite reduction and hydroxylamine oxidation by copper-containing dissimilatory nitrite reductase (NirK) from the aerobic ammonia-oxidizing archaeon, Nitrososphaera viennensis

2018

Kobayashi, S.; Hira, D.; Yoshida, K.; Toyofuku, M.; Shida, Y.; Ogasawara, W.; Yamaguchi, T.; Araki, N.; Oshiki, M.

Microbes Environ.

33

428-434

Links to other databases for reduced phenazine methosulfate

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Show Links (1 entry)

ChEBI

PubChem

-