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Ligand N-acetylglucosamine-(1-4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
Basic Ligand Information Molecular Structure
C9 4 H1 5 6 N8 O2 6 P2
N-acetylglucosamine-(1-4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol
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Roles as Enzyme Ligand
In Vivo Product in Enzyme-catalyzed Reactions (1 result)
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UDP-N-acetylglucosamine + Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol = UDP + N-acetylglucosamine-(1-4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol
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Product in Enzyme-catalyzed Reactions (1 result)
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UDP-N-acetylglucosamine + Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol = UDP + N-acetylglucosamine-(1-4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol
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Enzyme Kinetic Parameters
References & Links Literature References (2)
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The murG gene of Escherichia coli codes for the UDP-N-acetylglucosamine:N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase involved in the membrane steps of peptidoglycan synthesis
1991
Mengin-Lecreulx, D.; Textier, L.; Rousseau, M.; van Heijenoort, J.
J. Bacteriol.
173
4625-4636
Assay for identification of inhibitors for bacterial MraY translocase or MurG transferase
2000
Branstrom, A.A.; Midha, S.; Longley, C.B.; Han, K.; Baizman, E.R.; Axelrod, H.R.
Anal. Biochem.
280
315-319
Links to other databases for N-acetylglucosamine-(1-4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol