Ligand GDP-Man

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Basic Ligand Information

Molecular Structure
Picture of GDP-Man (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C16H25N5O16P2
GDP-Man
MVMSCBBUIHUTGJ-XIYWIPNQSA-N
Synonyms:
GDP-mannosylpyranose

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
GDP-mannosylpyranose + H2O = alpha-D-mannopyranose + GDP
show the reaction diagram
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Substrate in Enzyme-catalyzed Reactions (5 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
GDP-Man + phosphatidyl-myo-inositol = ?
show the reaction diagram
-
GDP-Man + H2O = Man-1-phosphate + GMP
show the reaction diagram
-
GDP-Man + H2O = GMP + Man-1-phosphate
show the reaction diagram
-

Inhibitor in Enzyme-catalyzed Reactions (2 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
IC50: 2 mM
-
inhibits FAD diphosphatase activity
-

Enzyme Kinetic Parameters

KM Value (1 result)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
40
-
same Km for GDP-Glc and GDP-Man

IC50 Value (1 result)

EC NUMBER
IC50 VALUE
IC50 VALUE MAXIMUM
COMMENTARY
LITERATURE
2
-
IC50: 2 mM

References & Links

Links to other databases for GDP-Man

ChEBI
PubChem
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PubChem