Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Acetyl-CoA carboxylase from rat liver. EC 6.4.1.2 Acetyl-CoA:carbon-dioxide ligase (ADP-forming)
1981
Tanabe, T.; Nakanishi, S.; Hashimoto, T.; Ogiwara, H.; Nikawa, J.I.; Numa, S.
Methods Enzymol.
71
5-16
-
Fatty acyl-CoA esters inhibit glucose-6-phosphatase in rat liver microsomes
1995
Fulceri, R.; Gamerucci, A.; Scott, H.M.; Giunti, R.; Burchell, A.; Benedetti, A.
Biochem. J.
307
391-397
Isolation of mutants of Acinetobacter calcoceticus deficient in wax ester synthesis and complementation of one mutation with a gene encoding a fatty acyl coenzyme A reductase
1997
Reiser, S.; Somerville, C.
J. Bacteriol.
179
2969-2975
Purification and characterization of short-chain, medium-chain, and long-chain acyl-CoA dehydrogenases from rat liver mitochondria. Isolation of the holo- and apoenzymes and conversion of the apoenzyme to the holoenzyme
1985
Ikeda, Y.; Okamura-Ikeda, K.; Tanaka, K.
J. Biol. Chem.
260
1311-1325
Purification and properties of rat liver acyl-CoA dehydrogenases and electron transfer flavoprotein
1981
Furuta, S.; Miyazawa, S.; Hashimoto, T.
J. Biochem.
90
1739-1750
Partial purification and characterization of sphingosine N-acyltransferase (ceramide synthase) from bovine liver mitochondrion-rich fraction
1998
Shimeno, H.; Soeda, S.; Sakamoto, M.; Kouchi, T.; Kowakame, T.; Kihara, T.
Lipids
33
601-605
Alteration of the fatty acid substrate specificity of lysophosphatidate acyltransferase by site-directed mutagenesis
1998
Morand, L.Z.; Patil, S.; Quasney, M.; German, J.B.
Biochem. Biophys. Res. Commun.
244
79-84
Acyl-CoA oxidase activity from Beauveria bassiana, an entomopathogenic fungus
2006
Alconada, T.M.; Juarez, M.P.
J. Basic Microbiol.
46
435-443
Human acyl-CoA dehydrogenase-9 plays a novel role in the mitochondrial beta-oxidation of unsaturated fatty acids
2005
Ensenauer, R.; He, M.; Willard, J.M.; Goetzman, E.S.; Corydon, T.J.; Vandahl, B.B.; Mohsen, A.W.; Isaya, G.; Vockley, J.
J. Biol. Chem.
280
32309-32316
Substrate specificity of Arabidopsis 3-ketoacyl-CoA synthases
2006
Blacklock, B.; Jaworski, J.
Biochem. Biophys. Res. Commun.
346
583-590
Gaining insight into the role of serine 282 in B. napus FAE1 condensing enzyme
2004
Katavic, V.; Barton, D.; Giblin, E.; Reed, D.; Kumar, A.; Taylor, D.
FEBS Lett.
562
118-124
Isolation and characterization of a gene affecting fatty acid elongation in Saccharomyces cerevisiae
1996
Toke, D.; Martin, C.
J. Biol. Chem.
271
18413-18422
ELO2 and ELO3, homologues of the Saccharomyces cerevisiae ELO1 gene, function in fatty acid elongation and are required for sphingolipid formation
1997
Oh, C.; Toke, D.; Mandala, S.; Martin, C.
J. Biol. Chem.
272
17376-17384
Inhibition of saturated very-long-chain fatty acid biosynthesis by mefluidide and perfluidone, selective inhibitors of 3-ketoacyl-CoA synthases
2012
Tresch, S.; Heilmann, M.; Christiansen, N.; Looser, R.; Grossmann, K.
Phytochemistry
76
162-171
Misexpression of fatty acid elongation1 in the Arabidopsis epidermis induces cell death and suggests a critical role for phospholipase A2 in this process
2009
Reina-Pinto, J.; Voisin, D.; Kurdyukov, S.; Faust, A.; Haslam, R.; Michaelson, L.; Efremova, N.; Franke, B.; Schreiber, L.; Napier, J.; Yephremov, A.
Plant Cell
21
1252-1272
Two Arabidopsis 3-ketoacyl CoA synthase genes, KCS20 and KCS2/DAISY, are functionally redundant in cuticular wax and root suberin biosynthesis, but differentially controlled by osmotic stress
2009
Lee, S.; Jung, S.; Go, Y.; Kim, H.; Kim, J.; Cho, H.; Park, O.; Suh, M.
Plant J.
60
462-475
Two modes of regulation of the fatty acid elongase ELOVL6 by the 3-ketoacyl-CoA reductase KAR in the fatty acid elongation cycle
2014
Naganuma, T.; Kihara, A.
PLoS ONE
9
e101823
Mammalian Lass6 and its related family members regulate synthesis of specific ceramides
2005
Mizutani, Y.; Kihara, A.; Igarashi, Y.
Biochem. J.
390
263-271
LASS3 (longevity assurance homologue 3) is a mainly testis-specific (dihydro)ceramide synthase with relatively broad substrate specificity
2006
Mizutani, Y.; Kihara, A.; Igarashi, Y.
Biochem. J.
398
531-538
Ceramide synthase 4 and de novo production of ceramides with specific N-acyl chain lengths are involved in glucolipotoxicity-induced apoptosis of INS-1 beta-cells
2011
Veret, J.; Coant, N.; Berdyshev, E.V.; Skobeleva, A.; Therville, N.; Bailbe, D.; Gorshkova, I.; Natarajan, V.; Portha, B.; Le Stunff, H.
Biochem. J.
438
177-189
Characterization of ceramide synthase 2 tissue distribution, substrate specificity, and inhibition by sphingosine 1-phosphate
2008
Laviad, E.L.; Albee, L.; Pankova-Kholmyansky, I.; Epstein, S.; Park, H.; Merrill, A.H.; Futerman, A.H.
J. Biol. Chem.
283
5677-5684
Ceramide synthesis is modulated by the sphingosine analog FTY720 via a mixture of uncompetitive and noncompetitive inhibition in an Acyl-CoA chain length-dependent manner
2009
Lahiri, S.; Park, H.; Laviad, E.L.; Lu, X.; Bittman, R.; Futerman, A.H.
J. Biol. Chem.
284
16090-16098
FTY720 inhibits ceramide synthases and up-regulates dihydrosphingosine 1-phosphate formation in human lung endothelial cells
2009
Berdyshev, E.V.; Gorshkova, I.; Skobeleva, A.; Bittman, R.; Lu, X.; Dudek, S.M.; Mirzapoiazova, T.; Garcia, J.G.; Natarajan, V.
J. Biol. Chem.
284
5467-5477
A critical role for ceramide synthase 2 in liver homeostasis II. insights into molecular changes leading to hepatopathy
2010
Pewzner-Jung, Y.; Brenner, O.; Braun, S.; Laviad, E.L.; Ben-Dor, S.; Feldmesser, E.; Horn-Saban, S.; Amann-Zalcenstein, D.; Raanan, C.; Berkutzki, T.; Erez-Roman, R.; Ben-David, O.; Levy, M.; Holzman, D.; Park, H.; Nyska, A.; Merrill, A.H.; Futerman, A.H.
J. Biol. Chem.
285
10911-10923
Modulation of ceramide synthase activity via dimerization
2012
Laviad, E.L.; Kelly, S.; Merrill, A.H.; Futerman, A.H.
J. Biol. Chem.
287
21025-21033
Enzyme activities of the ceramide synthases CERS2-6 are regulated by phosphorylation in the C-terminal region
2016
Sassa, T.; Hirayama, T.; Kihara, A.
J. Biol. Chem.
291
7477-7487
2-Hydroxy-ceramide synthesis by ceramide synthase family enzymatic basis for the preference of FA chain length
2008
Mizutani, Y.; Kihara, A.; Chiba, H.; Tojo, H.; Igarashi, Y.
J. Lipid Res.
49
2356-2364
Partial purification and characterization of sphingosine N-acyltransferase (ceramide synthase) from bovine liver mitochondrion-rich fraction
1998
Shimeno, H.; Soeda, S.; Sakamoto, M.; Kouchi, T.; Kowakame, T.; Kihara, T.
Lipids
33
601-605
Assaying ceramide synthase activity in vitro and in living cells using liquid chromatography-mass spectrometry
2016
Lim, X.Y.; Pickford, R.; Don, A.S.
Methods Mol. Biol.
1376
11-22
Cooperative synthesis of ultra long-chain fatty acid and ceramide during keratinocyte differentiation
2013
Mizutani, Y.; Sun, H.; Ohno, Y.; Sassa, T.; Wakashima, T.; Obara, M.; Yuyama, K.; Kihara, A.; Igarashi, Y.
PLoS ONE
8
e67317
The beta-ketoacyl-CoA synthase HvKCS1, encoded by Cer-zh, plays a key role in synthesis of barley leaf wax and germination of barley powdery mildew
2018
Li, C.; Haslam, T.M.; Krueger, A.; Schneider, L.M.; Mishina, K.; Samuels, L.; Yang, H.; Kunst, L.; Schaffrath, U.; Nawrath, C.; Chen, G.; Komatsuda, T.; von Wettstein-Knowles, P.
Plant Cell Physiol.
59
806-822
A beta-ketoacyl-CoA synthase is involved in rice leaf cuticular wax synthesis and requires a CER2-LIKE protein as a cofactor
2017
Wang, X.; Guan, Y.; Zhang, D.; Dong, X.; Tian, L.; Qu, L.Q.
Plant Physiol.
173
944-955
Production of long chain fatty alcohols found in bumblebee pheromones by Yarrowia lipolytica
2020
Hambalko, J.; Gajdos, P.; Nicaud, J.M.; Ledesma-Amaro, R.; Tupec, M.; Pichova, I.; Certik, M.
Front. Bioeng. Biotechnol.
8
593419
Three fatty acyl-coenzyme A reductases, BdFAR1, BdFAR2 and BdFAR3, are involved in cuticular wax primary alcohol biosynthesis in Brachypodium distachyon
2018
Wang, Y.; Sun, Y.; You, Q.; Luo, W.; Wang, C.; Zhao, S.; Chai, G.; Li, T.; Shi, X.; Li, C.; Jetter, R.; Wang, Z.
Plant Cell Physiol.
59
527-543
BdFAR4, a root-specific fatty acyl-coenzyme A reductase, is involved in fatty alcohol synthesis of root suberin polyester in Brachypodium distachyon
2021
Wang, Y.; Xu, J.; He, Z.; Hu, N.; Luo, W.; Liu, X.; Shi, X.; Liu, T.; Jiang, Q.; An, P.; Liu, L.; Sun, Y.; Jetter, R.; Li, C.; Wang, Z.
Plant J.
106
1468-1483