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Ligand 4-hydroxyestrone 4-O-glucuronide

Basic Ligand Information

Molecular Structure

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Roles as Enzyme Ligand

Product in Enzyme-catalyzed Reactions (1 result)

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Show Product (1 entry)

EC NUMBER

REACTION

REACTION DIAGRAM

LITERATURE

ENZYME 3D STRUCTURE

2.4.1.17

4-hydroxyestrone + UDP-glucuronate = UDP + 4-hydroxyestrone 4-O-glucuronide

488785, , 488790, 488782

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Enzyme Kinetic Parameters

References & Links

Literature References (3)

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Show Reference (3 entries)

BRENDA REFERENCE ID

PUBMED ID

TITLE

YEAR

AUTHORS

JOURNAL

VOLUME

PAGES

488782

9264550

Characterization of rabbit UDP-glucuronosyltransferase UGT1A7: tertiary amine glucuronidation is catalyzed by UGT1A7 and UGT1A4

1997

Bruck, M.; Li, Q.; Lamb, J.G.; Tukey, R.H.

Arch. Biochem. Biophys.

344

357-364

488785

9848110

Glucuronidation of catechol estrogens by expressed human UDP-glucuronosyltransferases (UGTs) 1A1, 1A3, and 2B7

1998

Cheng, Z.; Rios, G.R.; King, C.D.; Coffman, B.L.; Green, M.D.; Mojarrabi, B.; Mackenzie, P.I.; Tephly, T.R.

Toxicol. Sci.

45

52-57

488790

10575553

Structural and functional studies of UDP-Glucuronosyltransferases

1999

Radominska-Pandya, A.; Czernik, P.J.; Little, J.M.; Battaglia, E.; Mackenzie, P.I.

Drug Metab. Rev.

31

817-899

Links to other databases for 4-hydroxyestrone 4-O-glucuronide

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Show Links (1 entry)

ChEBI

PubChem

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