Ligand 3-methyl-L-tyrosine

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Basic Ligand Information

Molecular Structure
Picture of 3-methyl-L-tyrosine (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C10H13NO3
3-methyl-L-tyrosine
MQHLULPKDLJASZ-QMMMGPOBSA-N
Synonyms:
3-methyl-L-Tyr, 3-methyltyrosine
Pathway Source
Pathways

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (2 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
3-methyltyrosine + H2O2 = 3-hydroxy-5-methyltyrosine + H2O
show the reaction diagram
-
3-methyl-L-tyrosine + H2O2 + H+ = 3-hydroxy-5-methyl-L-tyrosine + H2O
show the reaction diagram
-

In Vivo Product in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
S-adenosyl-L-methionine + L-tyrosine = S-adenosyl-L-homocysteine + 3-methyl-L-tyrosine
show the reaction diagram
-
-

Substrate in Enzyme-catalyzed Reactions (6 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
3-methyltyrosine + H2O2 = 3-hydroxy-5-methyltyrosine + H2O
show the reaction diagram
-
3-methyl-L-tyrosine + H2O2 + H+ = 3-hydroxy-5-methyl-L-tyrosine + H2O
show the reaction diagram
-

Product in Enzyme-catalyzed Reactions (4 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
S-adenosyl-L-methionine + L-tyrosine = S-adenosyl-L-homocysteine + 3-methyl-L-tyrosine
show the reaction diagram
-
-
3-methylphenol + pyruvate + NH3 = 3-methyl-L-Tyr + H2O
show the reaction diagram
-

Inhibitor in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE

Enzyme Kinetic Parameters

kcat Value (Turnover Number) (2 results)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE
17.8
-
in 100 mM Tris-HCl, pH 9.0, at 25C
0.476
-
pH 9.0, 25C

KM Value (3 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.64
-
in 100 mM Tris-HCl, pH 9.0, at 25C
0.63
-
pH 9.0, 25C
4.1
-
-

References & Links

Links to other databases for 3-methyl-L-tyrosine

ChEBI
PubChem
ChEBI
PubChem