Ligand N-acetyl-D-glucosamine 6-phosphate

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Basic Ligand Information

Molecular Structure
Picture of N-acetyl-D-glucosamine 6-phosphate (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C8H16NO9P
N-acetyl-D-glucosamine 6-phosphate
BRGMHAYQAZFZDJ-RTRLPJTCSA-N
Synonyms:
2-acetamido-2-deoxy-D-glucose 6-phosphate, N-acetyl-D-glucosamine-6-phosphate, N-acetyl-D-glucosamine 6-phosphate[side 2], N-acetylglucosamine-6-phosphate, N-acetylglucosamine 6-phosphate


Show all pahtways known for Show all BRENDA pathways known for N-acetyl-D-glucosamine 6-phosphate

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (7 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
(R)-lactate + N-acetyl-D-glucosamine 6-phosphate = N-acetylmuramate 6-phosphate + H2O
show the reaction diagram
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In Vivo Product in Enzyme-catalyzed Reactions (6 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
acetyl-CoA + D-glucosamine 6-phosphate = CoA + N-acetyl-D-glucosamine 6-phosphate
show the reaction diagram
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ATP + N-acetyl-D-glucosamine = ADP + N-acetyl-D-glucosamine 6-phosphate
show the reaction diagram
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N-acetylmuramate 6-phosphate + H2O = (R)-lactate + N-acetyl-D-glucosamine 6-phosphate
show the reaction diagram
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N-acetyl-alpha-D-glucosamine 1-phosphate = N-acetyl-D-glucosamine 6-phosphate
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Substrate in Enzyme-catalyzed Reactions (10 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
N-acetyl-D-glucosamine 6-phosphate + H2O = N-acetyl-D-glucosamine + phosphate
show the reaction diagram
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N-acetylglucosamine 6-phosphate + H2O = N-acetylglucosamine + phosphate
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(R)-lactate + N-acetyl-D-glucosamine 6-phosphate = N-acetylmuramate 6-phosphate + H2O
show the reaction diagram
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Product in Enzyme-catalyzed Reactions (24 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
acetyl-CoA + D-glucosamine 6-phosphate = CoA + N-acetyl-D-glucosamine 6-phosphate
show the reaction diagram
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acetyl-CoA + D-glucosamine 6-phosphate = CoA + N-acetyl-D-glucosamine 6-phosphate
show the reaction diagram
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ADP + N-acetyl-D-glucosamine = AMP + N-acetyl-D-glucosamine 6-phosphate
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[protein]-Npi-phospho-L-histidine + N-acetyl-D-glucosamine [side 1] = [protein]-L-histidine + N-acetyl-D-glucosamine 6-phosphate[side 2]
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ATP + N-acetyl-D-glucosamine = ADP + N-acetyl-D-glucosamine 6-phosphate
show the reaction diagram
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D-glucosamine 6-phosphate + acetate = N-acetyl-D-glucosamine 6-phosphate + H2O
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N-acetyl-D-glucosamine-1-phosphate = N-acetyl-D-glucosamine-6-phosphate
show the reaction diagram
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N-acetyl-D-glucosamine-1-phosphate = N-acetyl-D-glucosamine-6-phosphate
show the reaction diagram
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Activator in Enzyme-catalyzed Reactions (9 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE

Inhibitor in Enzyme-catalyzed Reactions (4 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
substrate inhibition at high concentrations
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3D Structure of Enzyme-Ligand-Complex (PDB) (4 results)

Enzyme Kinetic Parameters

kcat Value (Turnover Number) (29 results)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE

KM Value (34 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
5.9
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in 25 mM HEPES, pH 7.4, 25 mM KCl, 1 mM MgCl2, 1 mM dithiothreitol, at 37C
1.6
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References & Links

Links to other databases for N-acetyl-D-glucosamine 6-phosphate

ChEBI
PubChem
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PubChem