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Basic Ligand Information
(dA)845-935, Oligo(dA), oligo(dA)12-18, poly(dA)50
Roles as Enzyme Ligand
Substrate in Enzyme-catalyzed Reactions (4 results)
dGTP + oligo(dA)12-18 = ?
dATP + poly(dA)50 = diphosphate + poly(dA)51
poly(dA) + H2O = 5'-phosphooligonucleotides + ?
Product in Enzyme-catalyzed Reactions (1 result)
poly(dm1A) + 2-oxoglutarate + O2 = poly(dA) + formaldehyde + succinate + CO2
Activator in Enzyme-catalyzed Reactions (4 results)
1.7-3.3 mM, activation of ATPase activity to 170-180% of control
170-180% activation at 1.7-3.3 mM, no activation by other polynucleotides
strong stimulation of ATPase activity
Inhibitor in Enzyme-catalyzed Reactions (1 result)
Enzyme Kinetic Parameters
KM Value (3 results)
Mn2+-activated enzyme, pH 8.2, 35°C
Mg2+-activated, pH 7.5, 35°C
References & Links
Links to other databases for poly(dA)