Ligand L-m-Tyr

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Basic Ligand Information

Molecular Structure
Picture of L-m-Tyr (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C9H11NO3
L-m-Tyr
JZKXXXDKRQWDET-QMMMGPOBSA-N
Synonyms:
(2S)-2-amino-3-(3-hydroxyphenyl)propanoic acid, 3-hydroxy-L-phenylalanine, 3-L-tyrosine, L-m-tyrosine, m-hydroxyphenylalanine, m-Tyr

Roles as Enzyme Ligand

In Vivo Product in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
L-phenylalanine + tetrahydrobiopterin + O2 = 3-hydroxy-L-phenylalanine + 4a-hydroxytetrahydrobiopterin
show the reaction diagram
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Substrate in Enzyme-catalyzed Reactions (8 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
dimethylallyl diphosphate + L-m-tyrosine = diphosphate + 4-(3-methylbut-2-enyl)-L-m-tyrosine + 6-(3-methylbut-2-enyl)-L-m-tyrosine
show the reaction diagram
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m-Tyr = ?
show the reaction diagram
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L-m-Tyr + pyridoxal phosphate = pyridoxamine phosphate + keto acid
show the reaction diagram
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(2S)-2-amino-3-(3-hydroxyphenyl)propanoic acid = (2E)-3-(3-hydroxyphenyl)prop-2-enoic acid + NH3
show the reaction diagram
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Product in Enzyme-catalyzed Reactions (4 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
3-hydroxy-trans-cinnamate + NH3 = 3-hydroxy-L-phenylalanine
show the reaction diagram
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3-hydroxy-trans-cinnamate + NH3 = 3-hydroxy-L-phenylalanine
show the reaction diagram
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Inhibitor in Enzyme-catalyzed Reactions (3 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
competitive
-

3D Structure of Enzyme-Ligand-Complex (PDB) (16 results)

Enzyme Kinetic Parameters

kcat Value (Turnover Number) (4 results)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE
0.0065
-
pH 7.5, 37°C, recombinant enzyme
0.00268
-
transamination
0.89
-
pH 8.3, 30°C
26
-
at pH 7.5 and 37°C

KM Value (5 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.9
-
pH 7.5, 37°C, recombinant enzyme
0.52
-
-
0.94
-
transamination
1.11
-
pH 8.3, 30°C
1.15
-
at pH 7.5 and 37°C

References & Links

Links to other databases for L-m-Tyr

ChEBI
PubChem
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PubChem