Ligand 5,10-methylenetetrahydropteroylhexaglutamate

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Basic Ligand Information

Molecular Structure
Picture of 5,10-methylenetetrahydropteroylhexaglutamate (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C45H58N12O21
5,10-methylenetetrahydropteroylhexaglutamate
WHTOOBRINZIYQS-LEFGHKRGSA-N
Synonyms:
5,10-methylenetetrahydrofolate-pentaglutamate, 5,10-methylenetetrahydrofolylpentaglutamate

Roles as Enzyme Ligand

Substrate in Enzyme-catalyzed Reactions (2 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
5-methyltetrahydropteroylmonoglutamate + 5,10-methylenetetrahydropteroylhexaglutamate = 5,10-methylenetetrahydropteroylmonoglutamate + 5-methyltetrahydropteroylhexaglutamate
show the reaction diagram
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5,10-methylenetetrahydrofolylpentaglutamate + 2'-deoxyuridylate = 7,8-dihydrofolylpentaglutamate + thymidine phosphate
show the reaction diagram
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Product in Enzyme-catalyzed Reactions (2 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
tetrahydropteroylhexaglutamate + 2-dehydropantoate = 5,10-methylenetetrahydropteroylhexaglutamate + 3-methyl-2-oxobutanoate + H2O
show the reaction diagram
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ATP + 5-formyltetrahydrofolate-pentaglutamate = ADP + phosphate + 5,10-methylenetetrahydrofolate-pentaglutamate
show the reaction diagram
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Enzyme Kinetic Parameters

References & Links

Links to other databases for 5,10-methylenetetrahydropteroylhexaglutamate

ChEBI
PubChem
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PubChem