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Ligand 6-phospho-2-dehydro-D-gluconate

Basic Ligand Information

Molecular Structure

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Roles as Enzyme Ligand

In Vivo Product in Enzyme-catalyzed Reactions (4 results)

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Show Natural Product (4 entries)

EC NUMBER

PROVEN IN VIVO REACTION

REACTION DIAGRAM

LITERATURE

ENZYME 3D STRUCTURE

1.1.1.43

6-phospho-D-gluconate + NAD(P)+ = 6-phospho-2-dehydro-D-gluconate + NAD(P)H

0

-

1.1.1.43

6-phosphono-D-gluconate + NAD(P)+ = 6-phospho-2-dehydro-D-gluconate + NAD(P)H

0

-

2.7.1.13

ATP + 2-dehydro-D-gluconate = ADP + 2-dehydro-6-phosphogluconate

640804

-

2.7.1.13

ATP + 2-dehydro-D-gluconate = ADP + 6-phospho-2-dehydro-D-gluconate

0

-

1.1.1.43

2 entries

2.7.1.13

2 entries

Substrate in Enzyme-catalyzed Reactions (1 result)

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Show Substrate (1 entry)

EC NUMBER

REACTION

REACTION DIAGRAM

LITERATURE

ENZYME 3D STRUCTURE

1.1.1.43

6-phospho-2-dehydro-D-gluconate + NAD(P)H = 6-phospho-D-gluconate + NAD(P)+

286814

-

Product in Enzyme-catalyzed Reactions (10 results)

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Show Product (10 entries)

EC NUMBER

REACTION

REACTION DIAGRAM

LITERATURE

ENZYME 3D STRUCTURE

1.1.1.43

6-phospho-D-gluconate + NAD(P)+ = 6-phospho-2-dehydro-D-gluconate + NAD(P)H

0

-

1.1.1.43

6-phospho-D-gluconate + NAD(P)+ = 6-phospho-2-dehydro-D-gluconate + NAD(P)H + H+

0

-

1.1.1.43

6-phospho-D-gluconate + NADP+ = 6-phospho-2-dehydro-D-gluconate + NADPH + H+

0

-

1.1.1.43

6-phosphono-D-gluconate + NAD(P)+ = 6-phospho-2-dehydro-D-gluconate + NAD(P)H

0

-

1.1.99.30

6-phospho-D-gluconate + oxidized anthraquinone-2,6-disulfonate = 6-phospho-D-arabino-hex-2-ulosonate + reduced anthraquinone-2,6-disulfonate

0

-

1.1.99.30

6-phospho-D-gluconate + oxidized benzyl viologen = 6-phospho-D-arabino-hex-2-ulosonate + reduced benzyl viologen

0

-

1.1.99.30

6-phospho-D-gluconate + oxidized carboxamido-methyl viologen = 6-phospho-D-arabino-hex-2-ulosonate + reduced carboxamido-methyl viologen

0

-

2.7.1.13

ATP + 2-dehydro-D-gluconate = ADP + 2-dehydro-6-phosphogluconate

640804, 640803, 640802

-

2.7.1.13

ATP + 2-dehydro-D-gluconate = ADP + 6-phospho-2-dehydro-D-gluconate

0

-

1.1.1.43

4 entries

1.1.99.30

3 entries

2.7.1.13

2 entries

2.7.1.45

ATP + 2-keto-D-gluconate = ADP + 6-phospho-2-keto-D-gluconate

0

-

Enzyme Kinetic Parameters

K_M Value (2 results)

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Show KM Value (2 entries)

EC NUMBER

KM VALUE [MM]

KM VALUE MAXIMUM [MM]

COMMENTARY

LITERATURE

1.1.1.43

0.38

-

with NADPH as coenzyme

286814

1.1.1.43

0.66

-

with NADH as coenzyme

286814

1.1.1.43

2 entries

References & Links

Literature References (4)

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Show Reference (4 entries)

BRENDA REFERENCE ID

PUBMED ID

TITLE

YEAR

AUTHORS

JOURNAL

VOLUME

PAGES

286814

13894458

Carbohydrate oxidation by Pseudomonas fluorescens VI. Conversion of 2-keto-6-phosphogluconate to pyruvate

1961

Frampton, E.W.; Wood, W.A.

J. Biol. Chem.

236

2571-2577

640802

13894459

Purification and properties of 2-ketogluconokinase from Aerobacter aerogenes

1961

Frampton, E.W.; Wood, W.A.

J. Biol. Chem.

236

2578-2580

640803

4212460

The utilization of 2-ketogluconate by Hydrogenomonas eutropha H 16

1974

Nandadasa, H.G.; Andreesen, M.; Schlegel, H.G.

Arch. Microbiol.

99

15-23

640804

10931350

Characterization of the 2-ketogluconate utilization operon in Pseudomonas aeruginosa PAO1

2000

Swanson, B.L.; Hager, P.; Phibbs, P.Jr.; Ochsner, U.; Vasil, M.L.; Hamood, A.N.

Mol. Microbiol.

37

561-573

Links to other databases for 6-phospho-2-dehydro-D-gluconate

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Show Links (1 entry)

ChEBI

PubChem