Ligand 4-hydroxypyridine

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Basic Ligand Information

Molecular Structure
Picture of 4-hydroxypyridine (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C5H5NO
4-hydroxypyridine
GCNTZFIIOFTKIY-UHFFFAOYSA-N
Synonyms:
pyridine-4-alcohol, pyridine-4-ol

Roles as Enzyme Ligand

Substrate in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
pyridine-4-ol + NADP+ = 3H-pyridine-4-one + NADPH
show the reaction diagram
-

Product in Enzyme-catalyzed Reactions (4 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
pyridine-4-aldehyde + NADH = pyridine-4-alcohol + NAD+
show the reaction diagram
-
pyridine-4-aldehyde + NADPH = pyridine-4-alcohol + NADP+
show the reaction diagram
-

Inhibitor in Enzyme-catalyzed Reactions (8 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
IC50: 2.3 mM
-
competitive inhibition
-

3D Structure of Enzyme-Ligand-Complex (PDB) (19 results)

Enzyme Kinetic Parameters

Ki Value (1 result)

EC NUMBER
KI VALUE [MM]
KI VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
1.4
-
pH 7.5, 25°C

IC50 Value (1 result)

EC NUMBER
IC50 VALUE
IC50 VALUE MAXIMUM
COMMENTARY
LITERATURE
2.3
-
IC50: 2.3 mM

References & Links

Links to other databases for 4-hydroxypyridine

ChEBI
PubChem
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PubChem