Ligand 2-bromophenol

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Basic Ligand Information

Molecular Structure
Picture of 2-bromophenol (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C6H5BrO
2-bromophenol
VADKRMSMGWJZCF-UHFFFAOYSA-N
Synonyms:
o-bromophenol
Pathway Source
Pathways

Roles as Enzyme Ligand

Substrate in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
2-bromophenol + pyruvate + NH3 = 2-bromo-L-Tyr + H2O
show the reaction diagram
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Product in Enzyme-catalyzed Reactions (5 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
2-bromo-L-Tyr + H2O = 2-bromophenol + pyruvate + NH3
show the reaction diagram
-

Inhibitor in Enzyme-catalyzed Reactions (2 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
competitive inhibition; competitive inhibition
-
cleavage of Tyr
-

3D Structure of Enzyme-Ligand-Complex (PDB) (1 result)

EC NUMBER
ENZYME 3D STRUCTURE

Enzyme Kinetic Parameters

Ki Value (1 result)

EC NUMBER
KI VALUE [MM]
KI VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.00174
-
isoform UGT1A6, at pH 7.4 and 37°C

IC50 Value (1 result)

EC NUMBER
IC50 VALUE
IC50 VALUE MAXIMUM
COMMENTARY
LITERATURE
0.0019
-
isoform UGT1A6, at pH 7.4 and 37°C

References & Links

Links to other databases for 2-bromophenol

ChEBI
PubChem
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PubChem