Ligand cholesta-5,7-dien-3beta-ol

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Basic Ligand Information

Molecular Structure
Picture of cholesta-5,7-dien-3beta-ol (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C27H44O
cholesta-5,7-dien-3beta-ol
UCTLRSWJYQTBFZ-DDPQNLDTSA-N
Synonyms:
(3beta)-cholesta-5,7-dien-3-ol, 5,7-cholestadien-3beta-ol, 7-dehydrocholesterol, cholest-5,7-dien-3beta-ol, cholesta-5,7-dien-3 beta-ol, cholesta-5,7-dien-3-beta-ol

Show all pahtways known for Show all pathways known for cholesta-5,7-dien-3beta-ol

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (4 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
7-dehydrocholesterol + NADPH + H+ = 7-oxocholesterol + NADP+ + H2O
show the reaction diagram
-

In Vivo Product in Enzyme-catalyzed Reactions (11 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
cholesta-5,7,24-trien-3beta-ol + NADPH = cholest-5,7-dien-3beta-ol + NADP+
show the reaction diagram
-
-

Substrate in Enzyme-catalyzed Reactions (8 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
7-dehydrocholesterol + NADPH + H+ = 7-oxocholesterol + NADP+ + H2O
show the reaction diagram
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7-dehydrocholesterol + 4 reduced adrenodoxin + 2 H+ + 2 O2 = 25-hydroxy-7-dehydrocholesterol + 26/27-hydroxy-7-dehydrocholesterol + 4 oxidzed adrenodoxin + 2 H2O
show the reaction diagram
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UDP-glucose + 7-dehydrocholesterol = UDP + 7-dehydrocholesterol 3-beta-D-glucoside
show the reaction diagram
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Product in Enzyme-catalyzed Reactions (17 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE

Inhibitor in Enzyme-catalyzed Reactions (3 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE

Enzyme Kinetic Parameters

kcat Value (Turnover Number) (1 result)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE
0.04
-
pH 7.4, 30°C

KM Value (4 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.0055
-
-
0.0011
-
pH 7.4, 30°C

Ki Value (1 result)

EC NUMBER
KI VALUE [MM]
KI VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.5
-
-

References & Links

Links to other databases for cholesta-5,7-dien-3beta-ol

ChEBI
PubChem
ChEBI
PubChem