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Ligand 4-methyltryptophan
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Basic Ligand Information
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open all tablesRoles as Enzyme Ligand
Substrate in Enzyme-catalyzed Reactions (7 results)
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EC NUMBER 
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
4-methyltryptophan + 6-methyltetrahydropterin + O2 = 5-hydroxy-4-methyltryptophan + 6-methyldihydropterin + H2O
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dimethylallyl diphosphate + 4-methyl-L-tryptophan = diphosphate + 4-methyl-3a-(2-methylbut-3-en-2-yl)-1,2,3,3a,8,8a-hexahydropyrrolo[2,3-b]indole-2-carboxylic acid + 4-methyl-3a-(3-methylbut-2-en-1-yl)-1,2,3,3a,8,8a-hexahydropyrrolo[2,3-b]indole-2-carboxylic acid + 4-methyl-5-(3-methylbut-2-en-1-yl)-L-tryptophan + 4-methyl-1-(3-methylbut-2-en-1-yl)-L-tryptophan
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dimethylallyl diphosphate + 4-methyl-L-tryptophan = diphosphate + 4-methyl-5-(3-methylbut-2-enyl)-L-tryptophan
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Product in Enzyme-catalyzed Reactions (1 result)
EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
Inhibitor in Enzyme-catalyzed Reactions (2 results)
EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
4-methyltryptophan is a competitive dead-end analogue of tryptophan used in kinetic studies of 4-DMATS
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Enzyme Kinetic Parameters
kcat Value (Turnover Number) (2 results)
EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE
KM Value (2 results)
EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
References & Links
Literature References (8)
Links to other databases for 4-methyltryptophan
ChEBI
PubChem
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Release 2023.1 (January 2023)
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