Ligand 3-Methylguanine
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
Basic Ligand Information
Molecular Structure

C6H7N5O
3-Methylguanine
XHBSBNYEHDQRCP-UHFFFAOYSA-N
Roles as Enzyme Ligand
In Vivo Product in Enzyme-catalyzed Reactions (2 results)
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
alkylated DNA + H2O = 3-methylguanine + ?
-
alkylated DNA + H2O = 7-methyladenine + 7-methylguanine + 3-methyladenine + 3-methylguanine + purine + 6-chloropurine + xanthine + DNA
-
Product in Enzyme-catalyzed Reactions (7 results)
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
alkylated DNA + H2O = 3-methyladenine + 3-methylguanine + ?
-
alkylated DNA + H2O = 3-methylguanine + ?
-
alkylated DNA + H2O = 3-methyladenine + 3-methylguanine + 7-methyladenine + 7-methylguanine + DNA
-
alkylated DNA + H2O = 3-methyladenine + 3-methylguanine + 7-methylguanine + 7-methyladenine + ?
-
alkylated DNA + H2O = 3-methyladenine + 7-methylguanine + 3-methylguanine
-
alkylated DNA + H2O = 7-methyladenine + 7-methylguanine + 3-methyladenine + 3-methylguanine + purine + 6-chloropurine + xanthine + DNA
-
3-methylguanosine + H2O = 3-methylguanine + D-ribose
-
Activator in Enzyme-catalyzed Reactions (2 results)
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
5 mM, enzyme activity 120%
-
Enzyme Kinetic Parameters
References & Links
Literature References (2)
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Purification and characterization of 3-methyladenine DNA glycosylase I from Escherichia coli
1987
Bjelland, S.; Seeberg, E.
Nucleic Acids Res.
15
2787-2801
Methylpurine DNA glycosylase of the hyperthermophilic archaeon Archaeoglobus fulgidus
2002
Birkeland, N.K.; Anensen, H.; Knaevelsrud, I.; Kristoffersen, W.; Bjoras, M.; Robb, F.T.; Klungland, A.; Bjelland, S.
Biochemistry
41
12697-12705
Links to other databases for 3-Methylguanine