Ligand gamma-butyrobetaine

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Basic Ligand Information

Molecular Structure
Picture of gamma-butyrobetaine (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C7H15NO2
gamma-butyrobetaine
JHPNVNIEXXLNTR-UHFFFAOYSA-N
Synonyms:
3-deydrocarnitine, 4-(trimethylammonio)butanoic acid, 4-butyrobetaine, 4-N-trimethylaminobutanoate, 4-N-trimethylaminobutyrate, 4-N-trmethylaminobutanoate, 4-trimethylaminobutanoate, 4-trimethylaminobutyrate, 4-Trimethylammoniobutanoate, alpha-actinin, alpha actinin, deoxycarnitine, deoxynorcarnitine


Show all pahtways known for Show all BRENDA pathways known for gamma-butyrobetaine

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (2 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
4-trimethylammoniobutanoate + 2-oxoglutarate + O2 = 3-hydroxy-4-trimethylammoniobutanoate + succinate + CO2
show the reaction diagram
alpha-actinin + H2O = ?
show the reaction diagram
-

In Vivo Product in Enzyme-catalyzed Reactions (5 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
phosphorylated alpha-actinin + H2O = alpha-actinin + phosphate
show the reaction diagram
-
-

Substrate in Enzyme-catalyzed Reactions (6 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
alpha-actinin + H2O = ?
show the reaction diagram
-
ATP + gamma-butyrobetaine + CoA = AMP + diphosphate + gamma-butyrobetainyl-CoA
show the reaction diagram
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Product in Enzyme-catalyzed Reactions (14 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
4-trimethylamino-1-butanol + 2 O2 + H2O = 4-trimethylaminobutanoate + 2 H2O2
show the reaction diagram
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-
N,N,N-trimethyl-3-aminopropionaldehyde + NAD+ + H2O = gamma-butyrobetaine + NADH + H+
show the reaction diagram
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crotonobetaine + reduced benzylviologen = gamma-butyrobetaine + oxidized benzylviologen
show the reaction diagram
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phosphorylated alpha-actinin + H2O = alpha-actinin + phosphate
show the reaction diagram
-
-

Inhibitor in Enzyme-catalyzed Reactions (14 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
competitive inhibition vs. L-carnitine
-
competitive inhibitor of (S)-carnitine oxidation; D-carnitine dehydrogenase, competitive inhibition
-
competitive inhibition
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3D Structure of Enzyme-Ligand-Complex (PDB) (1 result)

EC NUMBER
ENZYME 3D STRUCTURE

Enzyme Kinetic Parameters

kcat Value (Turnover Number) (5 results)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE

KM Value (10 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE

Ki Value (5 results)

EC NUMBER
KI VALUE [MM]
KI VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.03
-
pH 8.0, 37°C

References & Links

Links to other databases for gamma-butyrobetaine

ChEBI
PubChem
ChEBI
PubChem