Ligand (-)-menthol

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Basic Ligand Information

Molecular Structure
Picture of (-)-menthol (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C10H20O
(-)-menthol
NOOLISFMXDJSKH-ZDGBYWQASA-N
Synonyms:
(1R)-(-)-menthol, (1R)-menthol, (2S,5R)-5-methyl-2-(propan-2-yl)cyclohexan-1-ol, L-menthol

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (2 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
(-)-menthol + NADPH + O2 = p-menthane-3,8-diol + NADP+ + H2O
show the reaction diagram
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UDPglucose + L-menthol = UDP + L-menthyl-beta-D-glucoside
show the reaction diagram
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In Vivo Product in Enzyme-catalyzed Reactions (2 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
(-)-menthone + NADPH + H+ = (-)-menthol + NADP+
show the reaction diagram
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(2S,5R)-5-methyl-2-(propan-2-yl)cyclohexan-1-one + NADP+ = (2S,5R)-5-methyl-2-(propan-2-yl)cyclohexan-1-ol + (1S,2R,5R)-5-methyl-2-(propan-2-yl)cyclohexan-1-ol + NADPH + H+
show the reaction diagram
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Substrate in Enzyme-catalyzed Reactions (5 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
(1R)-menthol + NAD+ = (1R)-trans-p-menthan-3-one + NADH
show the reaction diagram
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l-menthol + O2 = menthone + H2O2
show the reaction diagram
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(-)-menthol + NADPH + O2 = p-menthane-3,8-diol + NADP+ + H2O
show the reaction diagram
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acetyl-CoA + (-)-menthol = CoA + (-)-menthyl acetate
show the reaction diagram
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UDPglucose + L-menthol = UDP + L-menthyl-beta-D-glucoside
show the reaction diagram
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Product in Enzyme-catalyzed Reactions (5 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
(2S,5R)-5-methyl-2-(propan-2-yl)cyclohexan-1-one + NADP+ = (2S,5R)-5-methyl-2-(propan-2-yl)cyclohexan-1-ol + (1S,2R,5R)-5-methyl-2-(propan-2-yl)cyclohexan-1-ol + NADPH + H+
show the reaction diagram
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-

Enzyme Kinetic Parameters

KM Value (4 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.059
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References & Links

Links to other databases for (-)-menthol

ChEBI
PubChem
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PubChem