Ligand deferiprone

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Basic Ligand Information

Molecular Structure
Picture of deferiprone (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C7H9NO2
deferiprone
TZXKOCQBRNJULO-UHFFFAOYSA-N
Synonyms:
1,2-dimethyl-3-hydroxypyrid-4-one

Show all pahtways known for Show all pathways known for deferiprone

Roles as Enzyme Ligand

Substrate in Enzyme-catalyzed Reactions (2 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE

Inhibitor in Enzyme-catalyzed Reactions (7 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
the loss of aconitase activity observed in cells should be ascribed to the chelation of available iron rather than to a direct effect of the chelator on the iron-sulfur clusters of the enzyme
-

Enzyme Kinetic Parameters

KM Value (4 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE

IC50 Value (1 result)

EC NUMBER
IC50 VALUE
IC50 VALUE MAXIMUM
COMMENTARY
LITERATURE
0.117
-
IC50 0.117 mM

References & Links

Links to other databases for deferiprone

ChEBI
PubChem
ChEBI
PubChem