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Ligand [Skp1-protein]-O-(N-acetyl-alpha-D-glucosaminyl)-trans-4-hydroxy-L-proline Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
Basic Ligand Information
C1 4 H2 1 N3 O8 R2
[Skp1-protein]-O-(N-acetyl-alpha-D-glucosaminyl)-trans-4-hydroxy-L-proline
[Skp1-protein]-O-(N-acetyl-D-glucosaminyl)hydroxyproline
Roles as Enzyme Ligand
In Vivo Product in Enzyme-catalyzed Reactions (1 result)
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UDP-N-acetylglucosamine + [Skp1-protein]-hydroxyproline = UDP + [Skp1-protein]-O-(N-acetyl-D-glucosaminyl)hydroxyproline
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Product in Enzyme-catalyzed Reactions (2 results)
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UDP-N-acetyl-alpha-D-glucosamine + [Skp1-protein]-trans-4-hydroxy-L-proline = UDP + [Skp1-protein]-O-(N-acetyl-alpha-D-glucosaminyl)-trans-4-hydroxy-L-proline
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UDP-N-acetylglucosamine + [Skp1-protein]-hydroxyproline = UDP + [Skp1-protein]-O-(N-acetyl-D-glucosaminyl)hydroxyproline
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Enzyme Kinetic Parameters
References & Links Literature References (3)
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Molecular cloning and expression of a UDP-N-acetylglucosamine (GlcNAc):hydroxyproline polypeptide GlcNAc-transferase that modifies Skp1 in the cytoplasm of Dictyostelium
2002
van der Wel, H.; Morris, H.R.; Panico, M.; Paxton, T.; Dell, A.; Kaplan, L.; West, C.M.
J. Biol. Chem.
277
46328-46337
Identification of a UDP-GlcNAc:Skp1-hydroxyproline GlcNAc-transferase in the cytoplasm of Dictyostelium
1999
Teng-umnuay, P.; van der Wel, H.; West, C.M.
J. Biol. Chem.
274
36392-36402
Complex glycosylation of Skp1 in Dictyostelium: implications for the modification of other eukaryotic cytoplasmic and nuclear proteins
2002
West, C.M.; van der Wel, H.; Gaucher, E.A.
Glycobiology
12
17R-27R
Links to other databases for [Skp1-protein]-O-(N-acetyl-alpha-D-glucosaminyl)-trans-4-hydroxy-L-proline