Ligand lipid II
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Basic Ligand Information
Molecular Structure

C94H157N9O25P2
lipid II
CALJPWOWZPDIQK-HZCKIVJASA-N
MurNAc-L-Ala-D-isoglutaminyl-L-Lys-D-Ala-D-Ala-diphospho-ditrans,octacis-undecaprenyl-GlcNAc, N-acetylmuramoyl-L-alanyl-D-isoglutaminyl-L-lysyl-D-alanyl-D-alanine-diphospho-ditrans,octacis-undecaprenyl-N-acetyl-D-glucosamine, N-acetylmuramoyl-L-alanyl-D-isoglutaminyl-L-lysyl-D-alanyl-D-alanine-diphosphoundecaprenyl-N-acetylglucosamine
Roles as Enzyme Ligand
Substrate in Enzyme-catalyzed Reactions (1 result)
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glycyl-tRNAGly + N-acetylmuramoyl-L-alanyl-D-isoglutaminyl-L-lysyl-D-alanyl-D-alanine-diphosphoundecaprenyl-N-acetylglucosamine = tRNAGly + N-acetylmuramoyl-L-alanyl-D-isoglutaminyl-L-lysyl-(N6-glycyl)-D-alanyl-D-alanine-diphosphoundecaprenyl-N-acetylglucosamine
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Product in Enzyme-catalyzed Reactions (1 result)
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UDP-N-acetylglucosamine + lipid I = UDP + lipid II
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Enzyme Kinetic Parameters
References & Links
Literature References (1)
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In vitro assembly of a complete, pentaglycine interpeptide bridge containing cell wall precursor (lipid II-Gly5) of Staphylococcus aureus
2004
Schneider, T.; Senn, M.M.; Berger-Bachi, B.; Tossi, A.; Sahl, H.G.; Wiedemann, I.
Mol. Microbiol.
53
675-685
Links to other databases for lipid II