Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
inosine 5'-phosphate + 3-acetylpyridine adenine dinucleotide + H2O = xanthosine 5'-phosphate + reduced 3-acetylpyridine adenine dinucleotide
-
inosine 5'-phosphate + 3-acetylpyridine adenine dinucleotide + H2O = xanthosine 5'-phosphate + reduced 3-acetylpyridine adenine dinucleotide
-
inosine 5'-phosphate + 3-acetylpyridine adenine dinucleotide + H2O = xanthosine 5'-phosphate + reduced 3-acetylpyridine adenine dinucleotide
-
inosine 5'-phosphate + 3-acetylpyridine adenine dinucleotide + H2O = xanthosine 5'-phosphate + reduced 3-acetylpyridine adenine dinucleotide
-
inosine 5'-phosphate + 3-acetylpyridine adenine dinucleotide + H2O = xanthosine 5'-phosphate + reduced 3-acetylpyridine adenine dinucleotide
-
inosine 5'-phosphate + 3-acetylpyridine adenine dinucleotide + H2O = xanthosine 5'-phosphate + reduced 3-acetylpyridine adenine dinucleotide
-
inosine 5'-phosphate + 3-acetylpyridine adenine dinucleotide + H2O = xanthosine 5'-phosphate + reduced 3-acetylpyridine adenine dinucleotide
-
inosine 5'-phosphate + 3-acetylpyridine adenine dinucleotide + H2O = xanthosine 5'-phosphate + reduced 3-acetylpyridine adenine dinucleotide
-
inosine 5'-phosphate + acetylpyridine adenine dinucleotide + H2O = xanthosine 5'-phosphate + reduced acetylpyridine adenine dinucleotide
-
inosine 5'-phosphate + acetylpyridine adenine dinucleotide + H2O = xanthosine 5'-phosphate + reduced acetylpyridine adenine dinucleotide
-
inosine 5'-phosphate + acetylpyridine adenine dinucleotide + H2O = xanthosine 5'-phosphate + reduced acetylpyridine adenine dinucleotide
-
inosine 5'-phosphate + acetylpyridine adenine dinucleotide + H2O = xanthosine 5'-phosphate + reduced acetylpyridine adenine dinucleotide
-
inosine 5'-phosphate + acetylpyridine adenine dinucleotide + H2O = xanthosine 5'-phosphate + reduced acetylpyridine adenine dinucleotide
-
inosine 5'-phosphate + acetylpyridine adenine dinucleotide + H2O = xanthosine 5'-phosphate + reduced acetylpyridine adenine dinucleotide
-
inosine 5'-phosphate + acetylpyridine adenine dinucleotide + H2O = xanthosine 5'-phosphate + reduced acetylpyridine adenine dinucleotide
-
inosine 5'-phosphate + acetylpyridine adenine dinucleotide + H2O = xanthosine 5'-phosphate + reduced acetylpyridine adenine dinucleotide
-
inosine 5'-phosphate + NAD+ + H2O = xanthosine 5'-phosphate + NADH
-
inosine 5'-phosphate + NAD+ + H2O = xanthosine 5'-phosphate + NADH
-
inosine 5'-phosphate + NAD+ + H2O = xanthosine 5'-phosphate + NADH
-
inosine 5'-phosphate + NAD+ + H2O = xanthosine 5'-phosphate + NADH
-
inosine 5'-phosphate + NAD+ + H2O = xanthosine 5'-phosphate + NADH
-
inosine 5'-phosphate + NAD+ + H2O = xanthosine 5'-phosphate + NADH
-
inosine 5'-phosphate + NAD+ + H2O = xanthosine 5'-phosphate + NADH
-
inosine 5'-phosphate + NAD+ + H2O = xanthosine 5'-phosphate + NADH
-
inosine 5'-phosphate + NAD+ + H2O = xanthosine 5'-phosphate + NADH + H+
-
inosine 5'-phosphate + NAD+ + H2O = xanthosine 5'-phosphate + NADH + H+
-
inosine 5'-phosphate + NAD+ + H2O = xanthosine 5'-phosphate + NADH + H+
-
inosine 5'-phosphate + NAD+ + H2O = xanthosine 5'-phosphate + NADH + H+
-
inosine 5'-phosphate + NAD+ + H2O = xanthosine 5'-phosphate + NADH + H+
-
inosine 5'-phosphate + NAD+ + H2O = xanthosine 5'-phosphate + NADH + H+
-
inosine 5'-phosphate + NAD+ + H2O = xanthosine 5'-phosphate + NADH + H+
-
inosine 5'-phosphate + NAD+ + H2O = xanthosine 5'-phosphate + NADH + H+
-
inosine 5'-phosphate + NAD+ = xanthosine 5'-phosphate + NADH + H+
-
inosine 5'-phosphate + NAD+ = xanthosine 5'-phosphate + NADH + H+
-
inosine 5'-phosphate + NAD+ = xanthosine 5'-phosphate + NADH + H+
-
inosine 5'-phosphate + NAD+ = xanthosine 5'-phosphate + NADH + H+
-
inosine 5'-phosphate + NAD+ = xanthosine 5'-phosphate + NADH + H+
-
inosine 5'-phosphate + NAD+ = xanthosine 5'-phosphate + NADH + H+
-
inosine 5'-phosphate + NAD+ = xanthosine 5'-phosphate + NADH + H+
-
inosine 5'-phosphate + NAD+ = xanthosine 5'-phosphate + NADH + H+
-
IMP + APAD+ + H2O = XMP + APADH + H+
-
IMP + APAD+ + H2O = XMP + APADH + H+
-
IMP + APAD+ + H2O = XMP + APADH + H+
-
IMP + APAD+ + H2O = XMP + APADH + H+
-
IMP + APAD+ + H2O = XMP + APADH + H+
-
IMP + APAD+ + H2O = XMP + APADH + H+
-
IMP + APAD+ + H2O = XMP + APADH + H+
-
IMP + APAD+ + H2O = XMP + APADH + H+
-
IMP + beta-NAD+ + H2O = XMP + beta-NADH + H+
-
IMP + beta-NAD+ + H2O = XMP + beta-NADH + H+
-
IMP + beta-NAD+ + H2O = XMP + beta-NADH + H+
-
IMP + beta-NAD+ + H2O = XMP + beta-NADH + H+
-
IMP + beta-NAD+ + H2O = XMP + beta-NADH + H+
-
IMP + beta-NAD+ + H2O = XMP + beta-NADH + H+
-
IMP + beta-NAD+ + H2O = XMP + beta-NADH + H+
-
IMP + beta-NAD+ + H2O = XMP + beta-NADH + H+
-
IMP + NAD+ + H2O = XMP + NADH + H+
-
IMP + NAD+ + H2O = XMP + NADH + H+
-
IMP + NAD+ + H2O = XMP + NADH + H+
-
IMP + NAD+ + H2O = XMP + NADH + H+
-
IMP + NAD+ + H2O = XMP + NADH + H+
-
IMP + NAD+ + H2O = XMP + NADH + H+
-
IMP + NAD+ + H2O = XMP + NADH + H+
-
IMP + NAD+ + H2O = XMP + NADH + H+
-
IMP + NAD+ = XMP + NADH + H+
-
IMP + NAD+ = XMP + NADH + H+
-
IMP + NAD+ = XMP + NADH + H+
-
IMP + NAD+ = XMP + NADH + H+
-
IMP + NAD+ = XMP + NADH + H+
-
IMP + NAD+ = XMP + NADH + H+
-
IMP + NAD+ = XMP + NADH + H+
-
IMP + NAD+ = XMP + NADH + H+
-
IMP + thiazole-4-carboxamide adenine dinucleotide + H2O = XMP + reduced thiazole-4-carboxamide adenine dinucleotide + H+
-
IMP + thiazole-4-carboxamide adenine dinucleotide + H2O = XMP + reduced thiazole-4-carboxamide adenine dinucleotide + H+
-
IMP + thiazole-4-carboxamide adenine dinucleotide + H2O = XMP + reduced thiazole-4-carboxamide adenine dinucleotide + H+
-
IMP + thiazole-4-carboxamide adenine dinucleotide + H2O = XMP + reduced thiazole-4-carboxamide adenine dinucleotide + H+
-
IMP + thiazole-4-carboxamide adenine dinucleotide + H2O = XMP + reduced thiazole-4-carboxamide adenine dinucleotide + H+
-
IMP + thiazole-4-carboxamide adenine dinucleotide + H2O = XMP + reduced thiazole-4-carboxamide adenine dinucleotide + H+
-
IMP + thiazole-4-carboxamide adenine dinucleotide + H2O = XMP + reduced thiazole-4-carboxamide adenine dinucleotide + H+
-
IMP + thiazole-4-carboxamide adenine dinucleotide + H2O = XMP + reduced thiazole-4-carboxamide adenine dinucleotide + H+
-
5-phospho-alpha-D-ribose 1-diphosphate + xanthine = 9-(5-phospho-beta-D-ribosyl)xanthine + diphosphate
-
5-phospho-alpha-D-ribose 1-diphosphate + xanthine = XMP + diphosphate
-
-
xanthine + 5-phospho-alpha-D-ribose 1-diphosphate = XMP + diphosphate
-
-
xanthine + 5-phospho-alpha-D-ribose 1-diphosphate = xanthosine 5'-phosphate + diphosphate
-
-
xanthine + 5-phospho-alpha-D-ribose 1-diphosphate = xanthosine 5'-phosphate + diphosphate
-
xanthine + 5-phospho-alpha-D-ribose 1-diphosphate = xanthosine 5'-phosphate + diphosphate
-
xanthine + 5-phospho-alpha-D-ribose 1-diphosphate = XMP + diphosphate
xanthine + 5-phospho-alpha-D-ribose 1-diphosphate = XMP + diphosphate
ATP + xanthosine = ADP + XMP
-
-
diphosphate + xanthosine = phosphate + 5'-XMP
-
4-nitrophenyl phosphate + xanthosine = 4-nitrophenol + XMP
-
-
5'-CMP + xanthosine = XMP + cytidine
-
-
5'-GMP + xanthosine = XMP + guanosine
-
-
5'-IMP + xanthosine = XMP + inosine
-
-
5'-UMP + xanthosine = XMP + uridine
-
-
GMP + H2O = XMP + NH3
-
-
P1,P4-bis(5'-xanthosyl) tetraphosphate + H2O = XTP + XMP
-
XDP + H2O = XMP + phosphate
-
-
XDP + H2O = XMP + phosphate
-
-
XTP + H2O = XMP + diphosphate
-
-
xanthosine 5'-triphosphate + H2O = xanthosine 5'-monophosphate + diphosphate
-
-
XDP + H2O = XMP + phosphate
-
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Purification and characterization of GMP synthetase from Yoshida sarcoma ascites cells
1987
Hirai, K.; Matsuda, Y.; Nakagawa, H.
J. Biochem.
102
893-902
-
Construction of a plasmid for high level expression of XMP aminase in Escherichia coli
1986
Maruyama, A.; Nishi, T.; Ozaki, A.; Ito, S.; Fujio, T.
Agric. Biol. Chem.
50
1879-1884
High level expression of XMP aminase in Escherichia coli and its application for the industrial production of 5-guanylic acid
1997
Fujio, T.; Nishi, T.; Ito, S.; Maruyama, A.
Biosci. Biotechnol. Biochem.
61
840-845
GMP synthetase
1985
Zalkin, H.
Methods Enzymol.
113
273-278
Nucleotide sequence of the guaA gene encoding GMP synthetase of Escherichia coli K12
1985
Tiedeman, A.A.; Smith, J.M.; Zalkin, H.
J. Biol. Chem.
260
8676-8679
GMP synthetase from Ehrlich ascites cells
1978
Spector, T.
Methods Enzymol.
51
219-224
GMP synthetase (Escherichia coli)
1978
Sakamoto, N.
Methods Enzymol.
51
213-218
Guanosine monophosphate synthetase from Ehrlich ascites cells. Multiple inhibition by pyrophosphate and nucleosides
1976
Spector, T.; Jones, T.E.; Krenitsky, T.A.; Harvey, R.J.
Biochim. Biophys. Acta
452
597-607
Guanosine monophosphate synthetase from Escherichia coli B-96. Inhibition by nucleosides
1975
Spector, T.; Beacham III, L.M.
J. Biol. Chem.
250
3101-3107
Studies with GMP synthetase from Ehrlich ascites cells. Purification, properties, and interactions with nucleotide analogs
1975
Spector, T.
J. Biol. Chem.
250
7372-7376
GMP synthetase from Escherichia coli B-96. Interactions with substrate analogs
1974
Spector, T.; Miller, R.L.; Fyfe, J.A.; Krenitsky, T.A.
Biochim. Biophys. Acta
370
585-591
Preferential utilization of glutamine for amination of xanthosine 5'-phosphate to guanosine 5'-phosphate by purified enzymes from Escherichia coli
1974
Lee, B.H.; Hartman, S.C.
Biochem. Biophys. Res. Commun.
60
918-925
Denaturation and renaturation of xanthosine 5¦-phosphate aminase
1972
Sakamoto, N.; Hatfield, G.W.; Moyed, H.S.
J. Biol. Chem.
247
5888-5891
Physical properties and subunit structure of xanthosine 5'-phosphate aminase
1972
Sakamoto, N.; Hatfield, G.W.; Moyed, H.S.
J. Biol. Chem.
247
5880-5887
-
Guanosine production and purine nucleotide biosynthetic enzymes in guanosine mutants of Bacillus subtilis
1979
Matsui, H.; Sato, K.; Enei, H.; Hirose, Y.
Agric. Biol. Chem.
43
1317-1323
Human GMP synthetase. Protein purification, cloning, and functional expression of cDNA
1994
Hirst, M.; Haliday, E.; Nakamura, J.; Lou, L.
J. Biol. Chem.
269
23830-23837
Biochemical characterization of human GMP synthetase
1995
Nakamura, J.; Lou, L.
J. Biol. Chem.
270
7347-7353
The glutamine hydrolysis function of human GMP synthetase. Identification of an essential active site cysteine
1995
Nakamura, J.; Straub, K.; Wu, J.; Lou, L.
J. Biol. Chem.
270
23450-23455
High-level production from a baculovirus expression system and biochemical characterization of human GMP synthetase
1995
Lou, L.; Nakamura, J.; Tsing, S.; Nguyen, B.; Chow, J.; Straub, K.; Chan, H.; Barnett, J.
Protein Expr. Purif.
6
487-495
Preliminary X-ray analysis of Escherichia coli GMP synthetase: determination of anomalous scattering factors for a cysteinyl mercury derivative
1994
Tesmer, J.J.G.; Stemmler, T.L.; Penner-Hahn, J.E.; Davisson, V.J.; Smith, J.L.
Proteins Struct. Funct. Genet.
18
394-403
-
The crystal structure of GMP synthetase reveals a novel catalytic triad and is a structural paradigm for two enzyme families
1996
Tesmer, J.J.G.; Klem, T.J.; Deras, M.L.; Davisson, V.J.; Smith, J.L.
Nat. Struct. Biol.
1
74-86
-
Production of guanosine by psicofuranine and decoyinine resistant mutants of Bacillus subtilis
1979
Matsui, H.; Sato, K.; Enei, H.; Hirose, Y.
Agric. Biol. Chem.
43
1739-1744
Properties of xanthosine 5'-monophosphate-amidotransferase from Escherichia coli
1977
Patel, N.; Moyed, H.S.; Kane, J.F.
Arch. Biochem. Biophys.
178
652-661
Characterization of the glutamine site of Escherichia coli guanosine 5'-monophosphate synthetase
1977
Zalkin, H.; Truitt, C.D.
J. Biol. Chem.
252
5431-5436
Xanthosine-5'-phosphate amidotransferase from Escherichia coli
1975
Patel, N.; Moyed, H.S.; Kane, J.F.
J. Biol. Chem.
250
2609-2613
Biosynthesis of guanosine 5'-phosphate. II. Amination of xanthosine 5'-phosphate by purified enzyme from pigeon liver
1958
Lagerkvist, U.
J. Biol. Chem.
233
143-149
Guanosine-5'-phosphate synthetase and guanosine-5'-phosphate kinase in rat hepatomas and kidney tumors
1981
Boritzki, T.J.; Jackson, R.C.; Morris, H.P.; Weber, G.
Biochim. Biophys. Acta
658
102-110
Purification and properties of adenylosuccinate synthetase from Yoshida sarcoma ascites tumor cells
1980
Matsuda, Y.; Shimura, K.; Shiraki, H.; Nakagawa, H.
Biochim. Biophys. Acta
616
340-350
Mammalian adenylosuccinate synthetase. Nucleotide monophosphate substrates and inhibitors
1976
Spector, T.; Miller, R.L.
Biochim. Biophys. Acta
445
509-517
Human adenylosuccinate synthetase. Partial purification, kinetic and regulatory properties of the enzyme from placenta
1974
Van der Weyden, M.B.; Kelly, W.N.
J. Biol. Chem.
249
7282-7289
carbamyl phosphate synthetase (glutamine-utilizing) from Escherichia coli
1985
Kaseman, D.S.; Meister, A.
Methods Enzymol.
113
305-326
High Km soluble 5'-nucleotidase from human placenta. Properties and allosteric regulation by IMP and ATP
1988
Spychala, J.; Madrid-Marina, V.; Fox, I.H.
J. Biol. Chem.
263
18759-18765
-
Properties of 5'-nucleotidase from nodules of pigeonpea (Cajanus cajan)
1986
Singh, A.; Singh, R.
Phytochemistry
25
2267-2270
Human placental cytoplasmic 5'-nucleotidase. Kinetic properties and inhibition
1986
Madrid-Marina, V.; Fox, I.H.
J. Biol. Chem.
261
444-452
Purification and some properties of cytosol 5'-nucleotidase from rat liver
1981
Itoh, R.
Biochim. Biophys. Acta
657
402-410
5-Aminoimidazole-4-carboxamide ribotide transformylase-IMP cyclohydrolase from human CCRF-CEM leukemia cells: purification, pH dependence and inhibitors
1994
Szabados, E.; Hindmarsh, E.J.; Phillips, L.; Duggleby, R.G.; Christopherson, R.I.
Biochemistry
33
14237-14245
Inhibitors of dihydroorotase, amidophosphoribosyltransferase and IMP cyclohydrolase as potential drugs
1995
Christopherson, R.I.; Williams, N.K.; Schoettle, S.L.; Szabados, E.; Hambley, T.W.; Manthey, M.K.
Biochem. Soc. Trans.
23
888-893
Guanine deaminase from rat brain. Purification, characteristics, and contribution to ammoniagenesis in the brain
1982
Miyamoto, S.; Ogawa, H.; Shiraki, H.; Nakagawa, H.
J. Biochem.
91
167-176
Dinucleosidasetetraphosphatase in rat liver and Artemia salina
1976
Vallejo, C.G.; Lobaton, C.D.; Quintanilla, M.; Sillero, A.; Sillero, M.A.G.
Biochim. Biophys. Acta
438
304-309
Dinucleosidetetraphosphatase from Ehrlich ascites tumour cells: inhibition by adenosine, guanosine and uridine 5-tetraphosphates
1982
Moreno, A.; Lobaton, C.D.; Sillero, M.A.G.; Sillero, A.
Int. J. Biochem.
14
629-634
Inhibition of inosine monophosphate dehydrogenase by sesquiterpene lactones
1987
Page, J.D.; Chaney, S.G.; Hall, I.H.; Lee, K.H.; Holbrook, D.J.
Biochim. Biophys. Acta
926
186-194
Action of the active metabolites of tiazofurin and ribavirin on purified IMP dehydrogenase
1988
Yamada, Y.; Natsumeda, Y.; Weber, G.
Biochemistry
27
2193-2196
Clinical and molecular impact of inhibition of IMP dehydrogenase activity by tiazofurin
1989
Weber, G.; Yamaji, Y.; Olah, E.; Natsumeda, Y.; Jayaram, H.N.; Lapis, E.; Zhen, W.; Prajda, N.; Hoffman, R.; Tricot, G.J.
Adv. Enzyme Regul.
28
335-356
IMP dehydrogenase and action of antimetabolites in human cultured blast cells
1990
Yamada, Y.; Goto, H.; Yoshino, M.; Ogasawara, N.
Biochim. Biophys. Acta
1051
209-214
Regulation of purine ribonucleotide synthesis by end product inhibition. I. Effect of purine nucleotides on inosine-5-phosphate dehydrogenase, xanthosine-5-phosphate aminase and adenylosuccinate lyase of Bacillus subtilis
1968
Ishii, K.; Shiio, I.
J. Biochem.
63
661-669
Inosine 5-phosphate dehydrogenase. Kinetic mechanism and evidence for selective reaction of the 6-chloro analog of inosine 5-phosphate with a cysteine residue at the inosine 5-phosphate site
1968
Brox, L.W.; Hampton, A.
Biochemistry
7
2589-2596
Studies on inosine monophosphate dehydrogenase. Steady state kinetics
1976
Heyde, E.; Nagabhushanam, A.; Vonarx, M.; Morrison, J.F.
Biochim. Biophys. Acta
429
645-660
Analogs of inosine 5-phosphate with phosphorus-nitrogen and phosphorus-sulfur bonds. Binding and kinetic studies with inosine 5-phosphate dehydrogenase
1969
Hampton, A.; Brox, L.W.; Bayer, M.
Biochemistry
8
2303-2311
Human IMP dehydrogenase. Kinetics and regulatory properties
1974
Holmes, E.W.; Pehlke, D.M.; Kelley, W.N.
Biochim. Biophys. Acta
364
209-217
IMP dehydrogenase, an enzyme linked with proliferation and malignancy
1975
Jackson, R.C.; Weber, G.
Nature
256
331-333
IMP dehydrogenase. II. Purification and properties of the enzyme from Yoshida sarcoma ascites tumor cells
1983
Okada, M.; Shimura, K.; Shiraki, H.; Nakagawa, H.
J. Biochem.
94
1605-1613
Partial purification, properties and regulation of inosine 5-phosphate dehydrogenase in normal and malignant rat tissues
1977
Jackson, R.C.; Morris, H.P.; Weber, G.
Biochem. J.
166
1-10
Inosinic acid dehydrogenase of sarcoma 180 cells
1968
Anderson, J.H.; Sartorelli, A.C.
J. Biol. Chem.
243
4762-4768
Rajagopalan KV, Handler P: Purification and properties of inosinic acid dehydrogenase from Escherichia coli
1969
Powell, G.; Rajagopalan, K.V.; Handler, P.
J. Biol. Chem.
244
4793-4797
Inosine monophosphate dehydrogenase from porcine (Sus scrofa domestica) thymus: Purification and properties
1993
Pugh, M.E.; Skibo, E.B.
Comp. Biochem. Physiol. B
2
381-387
Monovalent cation activation and kinetic mechanism of inosine 5'-monophosphate dehydrogenase
1996
Xiang,B.; Taylor, J.C.; Markham, G.D.
J. Biol. Chem.
271
1435-1440
Expression, purification, and characterization of inosine 5'-monophosphate dehydrogenase from Borrelia burgdorferi
1997
Zhou, X.; Cahoon, M.; Rosa, P.; Hedstrom, L.
J. Biol. Chem.
35
21977-21981
Characterization of human type I and type II IMP dehydrogenases
1993
Carr, S.F.; Papp, E.; Wu, J.C.; Natsumeda, Y.
J. Biol. Chem.
36
27286-27290
Calf thymus GMP reductase: control by XMP
1973
Stephens, R.W.; Whittaker, V.K.
Biochem. Biophys. Res. Commun.
53
975-981
Reaction mechanism and specificity of human GMP reductase. Substrates, inhibitors, activators, and inactivators
1979
Spector, T.; Jones, T.E.; Miller, R.L.
J. Biol. Chem.
254
2308-2315
Guanosine monophosphate reductase from Artemia salina: Inhibition by xanthosine monophosphate and activation by diguanosine tetraphosphate
1976
Renart, M.F.; Renart, J.; Sillero, M.A.G.; Sillero, A.
Biochemistry
15
4962-4966
Guanosine 5-phosphate reductase of human erythrocytes
1973
Mackenzie, J.J.; Sorensen, L.B.
Biochim. Biophys. Acta
327
282-294
NADPH-dependent GMP reductase isoenzyme of human (GMPR2). Expression, purification, and kinetic properties
2002
Deng, Y.; Wang, Z.; Ying, K.; Gu, S.; Ji, C.; Huang, Y.; Gu, X.; Wang, Y.; Xu, Y.; Li, Y.; Xie, Y.; Mao, Y.
Int. J. Biochem. Cell Biol.
34
1035-1050
Human AICAR transformylase: Role of the 4-Carboxamide of AICAR in binding and catalysis
2000
Wall, M.; Shim, J.H.; Benkovic, S.J.
Biochemistry
39
11303-11311
-
Orotate Phosphoribosyltransferase and orotidine-5'-monophosphate decarboxylase of black gram (phaseolus mungo) seedlings
1978
Ashihara, H.
Z. Pflanzenphysiol.
87
225-241
Glutamine phosphoribosylpyrophosphate amidotransferase from Escherichia coli. Purification and properties
1979
Messenger, L.J.; Zalkin, H.
J. Biol. Chem.
254
3382-3392
Human glutamine phosphoribosylpyrophosphate amidotransferase. Kinetic and regulatory properties
1973
Holmes, E.W.; McDonald, J.A.; McCord, J.M.; Wyngaarden, J.B.; Kelley, W.N.
J. Biol. Chem.
248
144-150
5-Phosphoribosylpyrophosphate amidotransferase from soybean root nodules: kinetic and regulatory properties
1984
Reynoldds, P.H.S.; Blevins, D.G.; Randall, D.D.
Arch. Biochem. Biophys.
229
623-631
Guanine and xanthine phosphoribosyltransfer activities of Lactobacillus casei and Escherichia coli. Their relationship to hypoxanthine and adenine phosphoribosyltransfer activities
1970
Krenitsky, T.A.; Neil, S.M.; Miller, R.L.
J. Biol. Chem.
245
2605-2611
Xanthine phosphoribosyltransferase in Leishmania: divalent cation activation
1982
Kidder, G.W.; Nolan, L.L.
J. Protozool.
29
405-409
Purine phosphoribosyltransferases from Leishmania donovani
1980
Tuttle, J.V.; Krenitsky, T.A.
J. Biol. Chem.
255
909-916
Xanthine phosphoribosyltransferase from Streptococcus faecalis. Properties and specificity
1974
Miller, R.L.; Adamczyk, D.L.; Fyfe, J.A.; Elion, G.B.
Arch. Biochem. Biophys.
165
349-358
Purification and comparative study of adenine and guanine phosphoribosyltransferases from Schizosaccharomyces pombe
1977
Nagy, M.; Ribet, A.M.
Eur. J. Biochem.
77
77-85
Crystal structure of Toxoplasma gondii hypoxanthine-guanine phosphoribosyltransferase with XMP, pyrophosphate, and two Mg2+ Ions Bound: insights into the catalytic mechanism
1999
Heroux, A.; White, E.L.; Ross, L.J.; Davis, R.L.; Borhani, D.W.
Biochemistry
38
14495-14506
Crystal structures of the Toxoplasma gondii hypoxanthine-guanine phosphoribosyltransferase-GMP and -IMP complexes: comparison of purine binding interactions with the XMP complex
1999
Heroux, A.; White, E.L.; Ross, L.J.; Borhani, D.W.
Biochemistry
38
14485-14494
Steady-state kinetics of the hypoxanthine-guanine-xanthine phosphoribosyltransferase from Tritrichomonas foetus: the role of threonine-47
1998
Munagala, N.R.; Chin, M.S.; Wang, C.C.
Biochemistry
37
4045-4051
Hypoxanthine, guanine, xanthine phosphoribosyltransferase activity in Cryptosporidium parvum
1998
Doyle, P.S.; Kanaani, J.; Wang, C.C.
Exp. Parasitol.
89
9-15
Altering the purine specificity of hypoxanthine-guanine-xanthine phosphoribosyltransferase from Tritrichomonas foetus by structure-based point mutations in the enzyme protein
1998
Munagala, N.R.; Wang, C.C.
Biochemistry
37
16612-16619
Purification and characterization of Plasmodium falciparum hypoxanthine-guanine-xanthine phosphoribosyltransferase and comparison with the human enzyme
1999
Keough, D.T.; Ng, A.L.; Winzor, D.J.; Emmerson, B.T.; de Jersey, J.
Mol. Biochem. Parasitol.
98
29-41
Unusual substrate specificity of a chimeric hypoxanthine-guanine phosphoribosyltransferase containing segments from the Plasmodium falciparum and human enzymes
2000
Sujay Subbayya, I.N.; Sukumaran, S.; Shivashankar, K.; Balaram, H.
Biochem. Biophys. Res. Commun.
272
596-602
A novel selective nucleoside phosphorylating enzyme from Morganella morganii
1999
Asano, Y.; Mihara, Y.; Yamada, H.
J. Biosci. Bioeng.
87
732-738
-
Pyrophosphate-dependent phosphofructokinase from the amoeba Naegleria fowleri, an AMP-sensitive enzyme
1993
Mertens, E.; De Jonckheere, J.; Van Schaftingen, E.
Biochem. J.
292
797-803
A mutation that alters the nucleotide specificity of elongation factor Tu, a GTP regulatory protein
1987
Hwang, Y.W.; Miller, D.L.
J. Biol. Chem.
262
13081-13085
N2-hydroxyguanosine 5'-monophosphate is a time-dependent inhibitor of Escherichia coli guanosine monophosphate synthetase
1999
Deras, M.L.; Chittur, S.V.; Davisson, V.J.
Biochemistry
38
303-310
Yeast orotidine-5'-phosphate decarboxylase: steady-state and pre-steady-state analysis of the kinetic mechanism of substrate decarboxylation
2000
Porter, D.J.T.; Short, S.A.
Biochemistry
39
11788-11800
Role of enzyme-ribofuranosyl contacts in the ground state and transition state for orotidine 5'-phosphate decarboxylase: a role for substrate destabilization?
2001
Miller, B.G.; Butterfoss, G.L.; Short, S.A.; Wolfenden, R.
Biochemistry
40
6227-6232
Mechanism for acivicin inactivation of triad glutamine amidotransferases
2001
Chittur, S.V.; Klem, T.J.; Shafer, C.M.; Davisson, V.J.
Biochemistry
40
876-887
Dissecting a charged network at the active site of orotidine-5'-phosphate decarboxylase
2001
Miller, B.G.; Snider, M.J.; Wolfenden, R.; Short, S.A.
J. Biol. Chem.
276
15174-15176
Adenosine is the primary precursor of all purine nucleotides in Trichomonas vaginalis
2003
Munagala, N.R.; Wang, C.C.
Mol. Biochem. Parasitol.
127
143-149
Characteristics, substrate analysis, and intracellular location of Saccharomyces cerevisiae UMP kinase
1993
Jong, A.; Yeh, Y.; Ma, J.J.
Arch. Biochem. Biophys.
304
197-204
-
corresponding Author: Dr. Alexander Yakunin, C.H. Best Institute, 112 College St. Room 72, Toronto On M5G 1L6, Canada
2007
Proudfoot, M.
Private Communication
10
1-1
Kinetic and biochemical characterization of Plasmodium falciparum guanosine 5-monophosphate synthetase
2007
Bhat, J.Y.; Shastri, B.G.; Balaram, H.
Biochem. J.
409
263-273
The effects of removing the GAT domain from E. coli GMP synthetase
2006
Abbott, J.L.; Newell, J.M.; Lightcap, C.M.; Olanich, M.E.; Loughlin, D.T.; Weller, M.A.; Lam, G.; Pollack, S.; Patton, W.A.
Protein J.
25
483-491
Adenosine as a metabolic regulator of tissue function: production of adenosine by cytoplasmic 5'-nucleotidases
2006
Borowiec, A.; Lechward, K.; Tkacz-Stachowska, K.; Skladanowski, A.C.
Acta Biochim. Pol.
53
269-278
The extraordinary specificity of xanthine phosphoribosyltransferase from Bacillus subtilis elucidated by reaction kinetics, ligand binding, and crystallography
2006
Arent, S.; Kadziola, A.; Larsen, S.; Neuhard, J.; Jensen, K.F.
Biochemistry
45
6615-6627
Kinetic characterization of inosine monophosphate dehydrogenase of Leishmania donovani
2007
Dobie, F.; Berg, A.; Boitz, J.M.; Jardim, A.
Mol. Biochem. Parasitol.
152
11-21
Structure and inhibition of orotidine 5-monophosphate decarboxylase from Plasmodium falciparum
2008
Langley, D.B.; Shojaei, M.; Chan, C.; Lok, H.C.; Mackay, J.P.; Traut, T.W.; Guss, J.M.; Christopherson, R.I.
Biochemistry
47
3842-3854
Structural diversity and plasticity associated with nucleotides targeting orotidine monophosphate decarboxylase
2008
Poduch, E.; Wei, L.; Pai, E.F.; Kotra, L.P.
J. Med. Chem.
51
432-438
Inhibition of orotidine 5-monophosphate decarboxylase and its therapeutic potential
2008
Meza-Avina, M.E.; Wei, L.; Buhendwa, M.G.; Poduch, E.; Bello, A.M.; Pai, E.F.; Kotra, L.P.
Mini Rev. Med. Chem.
8
239-247
Acidic residues in the purine binding site govern the 6-oxopurine specificity of the Leishmania donovani xanthine phosphoribosyltransferase
2010
Ullman, B.; Cyr, N.; Choi, K.; Jardim, A.
Int. J. Biochem. Cell Biol.
42
253-262
Crystal structure of the ATPPase subunit and its substrate-dependent association with the GATase subunit: a novel regulatory mechanism for a two-subunit-type GMP synthetase from Pyrococcus horikoshii OT3
2010
Maruoka, S.; Horita, S.; Lee, W.C.; Nagata, K.; Tanokura, M.
J. Mol. Biol.
395
417-429
Ammonia channeling in Plasmodium falciparum GMP synthetase: investigation by NMR spectroscopy and biochemical assays
2011
Bhat, J.Y.; Venkatachala, R.; Singh, K.; Gupta, K.; Sarma, S.P.; Balaram, H.
Biochemistry
50
3346-3356
-
5'-Nucleotidases and their new roles in NAD+ and phosphate metabolism
2010
Bogan, K.; Brenner, C.
New J. Chem.
34
845-853
Bacillus anthracis inosine 5-monophosphate dehydrogenase in action: the first bacterial series of structures of phosphate ion-, substrate-, and product-bound complexes
2012
Makowska-Grzyska, M.; Kim, Y.; Wu, R.; Wilton, R.; Gollapalli, D.R.; Wang, X.K.; Zhang, R.; Jedrzejczak, R.; Mack, J.C.; Maltseva, N.; Mulligan, R.; Binkowski, T.A.; Gornicki, P.; Kuhn, M.L.; Anderson, W.F.; Hedstrom, L.; Joachimiak, A.
Biochemistry
51
6148-6163
Biochemical characterization of recombinant guaA-encoded guanosine monophosphate synthetase (EC 6.3.5.2) from Mycobacterium tuberculosis H37Rv strain
2012
Franco, T.M.; Rostirolla, D.C.; Ducati, R.G.; Lorenzini, D.M.; Basso, L.A.; Santos, D.S.
Arch. Biochem. Biophys.
517
1-11
Substrate activation and conformational dynamics of guanosine 5'-monophosphate synthetase
2013
Oliver, J.C.; Linger, R.S.; Chittur, S.V.; Davisson, V.J.
Biochemistry
52
5225-5235
Substrate-induced conformational changes in Plasmodium falciparum guanosine monophosphate synthetase
2011
Bhat, J.Y.; Venkatachala, R.; Balaram, H.
FEBS J.
278
3756-3768
Substrate specificity and oligomerization of human GMP synthetase
2013
Welin, M.; Lehtiö, L.; Johansson, A.; Flodin, S.; Nyman, T.; Trésaugues, L.; Hammarström, M.; Gräslund, S.; Nordlund, P.
J. Mol. Biol.
425
4323-4333
Kinetic mechanism of Plasmodium falciparum hypoxanthine-guanine-xanthine phosphoribosyltransferase
2015
Roy, S.; Nagappa, L.K.; Prahladarao, V.S.; Balaram, H.
Mol. Biochem. Parasitol.
204
111-120
Increased riboflavin production by manipulation of inosine 5-monophosphate dehydrogenase in Ashbya gossypii
2015
Buey, R.M.; Ledesma-Amaro, R.; Balsera, M.; de Pereda, J.M.; Revuelta, J.L.
Appl. Microbiol. Biotechnol.
99
9577-9589
Mucin biosynthesis. Enzymic properties of human-tracheal epithelial GDP-L-fucose:beta-D-galactoside alpha-(1->2)-L-fucosyltransferase
1986
Cheng, P.W.; DeVries, A.
Carbohydr. Res.
149
253-261
-
Biochemical characterization of Mycobacterium tuberculosis IMP dehydrogenase: kinetic mechanism, metal activation and evidence of a cooperative system
2014
Rostirolla, D.; Milech De Assuncao, T.; Bizarro, C.; Basso, L.; Santos, D.
RSC Adv.
4
26271-26287
Conformational changes involving ammonia tunnel formation and allosteric control in GMP synthetase
2014
Oliver, J.C.; Gudihal, R.; Burgner, J.W.; Pedley, A.M.; Zwierko, A.T.; Davisson, V.J.; Linger, R.S.
Arch. Biochem. Biophys.
545
22-32
Identification, heterologous expression, and functional characterization of Bacillus subtilis YutF, a HAD superfamily 5'-nucleotidase with broad substrate specificity
2016
Zakataeva, N.P.; Romanenkov, D.V.; Yusupova, Y.R.; Skripnikova, V.S.; Asahara, T.; Gronskiy, S.V.
PLoS ONE
11
e0167580
Polyphosphate-dependent synthesis of ATP and ADP by the family-2 polyphosphate kinases in bacteria
2008
Nocek, B.; Kochinyan, S.; Proudfoot, M.; Brown, G.; Evdokimova, E.; Osipiuk, J.; Edwards, A.; Savchenko, A.; Joachimiaka, A.; Yakunin, A.
Proc. Natl. Acad. Sci. USA
105
17730-17735
HOME
login
history
all enzymes
BRENDA home
Show all BRENDA pathways known for XMP
close all tables 
open all tables
top
Information
