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Ligand base

Basic Ligand Information

Pathway Source

Pathways

KEGG

Aminobenzoate degradation, Biosynthesis of secondary metabolites, Cutin, suberine and wax biosynthesis, Fatty acid degradation, Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate, Lysine degradation, Mannose type O-glycan biosynthesis, Microbial metabolism in diverse environments, Mucin type O-glycan biosynthesis, Nucleotide metabolism, Pantothenate and CoA biosynthesis, Pathways of neurodegeneration - multiple diseases, Purine metabolism, Selenocompound metabolism more

MetaCyc

(4R)-carveol and (4R)-dihydrocarveol degradation, (4S)-carveol and (4S)-dihydrocarveol degradation, (5R)-carbapenem carboxylate biosynthesis, (aminomethyl)phosphonate degradation, (R)-camphor degradation, (S)-camphor degradation, 1,4-dihydroxy-6-naphthoate biosynthesis I, 10,13-epoxy-11-methyl-octadecadienoate biosynthesis, 15-epi-lipoxin biosynthesis, 2,2'-bis-(4-hydroxy-3-methybut-2-enyl)-beta,beta-carotene monoglucoside biosynthesis, 2,4,6-trinitrotoluene degradation, 2,4-xylenol degradation to protocatechuate, 2-keto-L-gulonate biosynthesis, 3,4-dichlorobenzoate degradation, 3-chlorobenzoate degradation II (via protocatechuate), 3-methylquinoline degradation, 3-phenylpropanoate degradation, 4,4'-diapolycopenedioate biosynthesis, 4-aminobenzoate biosynthesis III, 4-ethylphenol degradation (anaerobic), 4-nitrotoluene degradation II, 5,6-dimethylbenzimidazole biosynthesis II (anaerobic), 5-deoxystrigol biosynthesis, 5-hydroxybenzimidazole biosynthesis (anaerobic), 5-hydroxymethylfurfural degradation, 5-methoxy-6-methylbenzimidazole biosynthesis (anaerobic), 5-methoxybenzimidazole biosynthesis (anaerobic), 6-diazo-5-oxo-L-norleucine biosynthesis, 6-methoxypodophyllotoxin biosynthesis, 7,8-dimethylmenaquinone biosynthesis, abscisic acid biosynthesis shunt, abscisic acid degradation to phaseic acid, actinorhodin biosynthesis, adamantanone degradation, adenine and adenosine salvage III, adenine salvage, adenosine nucleotides degradation I, adenosine nucleotides degradation II, adlupulone and adhumulone biosynthesis, alliin metabolism, alpha-cyclopiazonate biosynthesis, alpha-tomatine biosynthesis, Amaryllidacea alkaloids biosynthesis, ammonia oxidation I (aerobic), ammonia oxidation III, anandamide lipoxygenation, anditomin biosynthesis, androstenedione degradation I (aerobic), androstenedione degradation II (anaerobic), aniline degradation, arachidonate metabolites biosynthesis, arginomycin biosynthesis, aromatic biogenic amine degradation (bacteria), arsenate reduction (respiratory), arsonoacetate degradation, ascorbate recycling (cytosolic), aspirin triggered resolvin D biosynthesis, aspirin triggered resolvin E biosynthesis, aspoquinolone biosynthesis, astaxanthin biosynthesis (bacteria, fungi, algae), astaxanthin biosynthesis (flowering plants), atrazine degradation II, aureothin biosynthesis, aurone biosynthesis, autoinducer AI-2 biosynthesis I, autoinducer AI-2 biosynthesis II (Vibrio), bacilysin biosynthesis, bacterioruberin biosynthesis, benzene degradation IV (anaerobic), beta-carboline biosynthesis, beta-dihydromenaquinone-9 biosynthesis, beta-pyrazole-1-ylalanine biosynthesis, betacyanin biosynthesis (via dopamine), bile acid biosynthesis, neutral pathway, biotin biosynthesis from 8-amino-7-oxononanoate III, biotin-carboxyl carrier protein assembly, bis(guanylyl molybdopterin) cofactor sulfurylation, bisucaberin biosynthesis, blasticidin S biosynthesis, bombykol biosynthesis, brassinolide biosynthesis I, brassinolide biosynthesis II, brassinosteroids inactivation, bupropion degradation, butachlor degradation, C20 prostanoid biosynthesis, caffeine degradation II, calendate biosynthesis, canavanine biosynthesis, candicidin biosynthesis, cannabinoid biosynthesis, canthaxanthin biosynthesis, carbofuran degradation I, carbofuran degradation II, carbon tetrachloride degradation I, carbon tetrachloride degradation II, carnosate bioynthesis, cephamycin C biosynthesis, chanoclavine I aldehyde biosynthesis, chaxamycin biosynthesis, chitin degradation II (Vibrio), chitin degradation III (Serratia), chloramphenicol biosynthesis, chlorate reduction, chlorobactene biosynthesis, cholesterol degradation to androstenedione I (cholesterol oxidase), cholesterol degradation to androstenedione II (cholesterol dehydrogenase), cholesterol degradation to androstenedione III (anaerobic), choline degradation I, cinchona alkaloids biosynthesis, cis-geranyl-CoA degradation, cis-zeatin biosynthesis, citronellol degradation, cob(II)yrinate a,c-diamide biosynthesis I (early cobalt insertion), cocaine biosynthesis, coelimycin P1 biosynthesis, coenzyme B biosynthesis, coenzyme M biosynthesis I, coenzyme M biosynthesis II, colibactin biosynthesis, colupulone and cohumulone biosynthesis, creatinine degradation III, crocetin biosynthesis, cuticular wax biosynthesis, cyclohexane-1-carboxyl-CoA biosynthesis, cyclooctatin biosynthesis, cytidylyl molybdenum cofactor sulfurylation, cytochrome c biogenesis (system I type), D-arginine degradation, D-cycloserine inhibition of pyridoxal 5'-phosphate, D-xylose degradation IV, decaprenoxanthin diglucoside biosynthesis, dehydroabietic acid biosynthesis, desferrioxamine B biosynthesis, desferrioxamine E biosynthesis, di-homo-gamma-linolenate metabolites biosynthesis, diadinoxanthin and fucoxanthin biosynthesis, diazepinomicin biosynthesis, dimethylsulfoniopropanoate biosynthesis III (algae and phytoplankton), dimorphecolate biosynthesis, diphenylamine degradation, docosahexaenoate biosynthesis I (lower eukaryotes), docosahexaenoate biosynthesis III (6-desaturase, mammals), docosahexaenoate biosynthesis IV (4-desaturase, mammals), docosahexaenoate metabolites biosynthesis, dTDP-beta-L-evernitrose biosynthesis, dTDP-D-desosamine biosynthesis, ecdysone and 20-hydroxyecdysone biosynthesis, ellagic acid degradation to urolithins, Entner-Doudoroff pathway II (non-phosphorylative), ergotamine biosynthesis, ergothioneine biosynthesis I (bacteria), ergothioneine biosynthesis II (fungi), ethylbenzene degradation (anaerobic), eumelanin biosynthesis, factor 430 biosynthesis, fatty acid alpha-oxidation I (plants), firefly bioluminescence, flexixanthin biosynthesis, fosfomycin biosynthesis, FR-900098 and FR-33289 antibiotics biosynthesis, furfural degradation, gamma-coniciene and coniine biosynthesis, gentamicin biosynthesis, gibberellin biosynthesis IV (Gibberella fujikuroi), gibberellin biosynthesis V, ginkgotoxin biosynthesis, glucose degradation (oxidative), glucosinolate biosynthesis from dihomomethionine, glutathione amide metabolism, glutathione-mediated detoxification I, glutathione-mediated detoxification II, glycine betaine biosynthesis I (Gram-negative bacteria), glycogen biosynthesis II (from UDP-D-Glucose), glycolipid desaturation, glycosaminoglycan-protein linkage region biosynthesis, glyphosate degradation III, heliocides biosynthesis, heme a biosynthesis, heme b biosynthesis III (from siroheme), heme d1 biosynthesis, heme degradation III, heme degradation IV, heme degradation VI, heme degradation VII, hispidol and hispidol 4'-O-beta-D-glucoside biosynthesis, holomycin biosynthesis, hopanoid biosynthesis (bacteria), hydrogen oxidation I (aerobic), hypericin biosynthesis, hypoglycin biosynthesis, hypusine biosynthesis, icosapentaenoate biosynthesis I (lower eukaryotes), icosapentaenoate biosynthesis II (6-desaturase, mammals), icosapentaenoate metabolites biosynthesis, indole glucosinolate activation (herbivore attack), indole-3-acetate biosynthesis II, indole-3-acetate degradation II, indole-3-acetate inactivation I, indole-3-acetate inactivation II, indole-3-acetate inactivation IV, indole-3-acetate inactivation VII, isethionate degradation, isoprene degradation, isorenieratene biosynthesis I (actinobacteria), isorenieratene biosynthesis II (Chlorobiaceae), juglone biosynthesis, K-252 biosynthesis, L-arabinose degradation IV, L-arginine degradation XII, L-ascorbate biosynthesis III (D-sorbitol pathway), L-ascorbate biosynthesis V (euglena, D-galacturonate pathway), L-ascorbate biosynthesis VIII (engineered pathway), L-ascorbate degradation V, L-asparagine degradation II, L-cysteine biosynthesis V (mycobacteria), L-cysteine biosynthesis VI (reverse transsulfuration), L-dopa degradation II (bacterial), L-histidine degradation VI, L-lysine degradation V, L-methionine degradation I (to L-homocysteine), L-tryptophan degradation V (side chain pathway), L-tryptophan degradation XI (mammalian, via kynurenine), labdane-type diterpenes biosynthesis, lactucaxanthin biosynthesis, leinamycin biosynthesis, limonene degradation IV (anaerobic), linoleate metabolites biosynthesis, lipoate biosynthesis and incorporation I, lipoate biosynthesis and incorporation II, lipoate biosynthesis and incorporation III (Bacillus), lipoate biosynthesis and incorporation V (mammals), lipoate salvage I, lipoate salvage II, lipoxin biosynthesis, lupulone and humulone biosynthesis, lycopadiene biosynthesis, m-xylene degradation (anaerobic), malbrancheamide biosynthesis, mandelate degradation I, melatonin degradation II, methiin metabolism, methylamine degradation II, methylarsonous acid detoxification III, methylphosphonate degradation I, methylphosphonate degradation II, mitomycin biosynthesis, molybdenum cofactor sulfulylation (eukaryotes), molybdopterin biosynthesis, mycofactocin biosynthesis, mycolate biosynthesis, myxol-2' fucoside biosynthesis, NAD salvage pathway V (PNC V cycle), naphthalene degradation (anaerobic), naphthomycin biosynthesis, neurosporaxanthin biosynthesis, neurosporene biosynthesis, nicotinate degradation II, nicotine degradation I (pyridine pathway), nicotine degradation II (pyrrolidine pathway), nicotine degradation IV, nicotine degradation V, NiFe(CO)(CN)2 cofactor biosynthesis, nitrilotriacetate degradation, nopaline degradation, octane oxidation, octopine degradation, okenone biosynthesis, oligomeric urushiol biosynthesis, papaverine biosynthesis, penigequinolone biosynthesis, perchlorate reduction, phenylethylamine degradation II, phenylphenalenone biosynthesis, phosalacine biosynthesis, phosphinothricin tripeptide biosynthesis, phylloquinol biosynthesis, picolinate degradation, pinoresinol degradation, plasmalogen biosynthesis II (anaerobic), platensimycin biosynthesis, polyacyltrehalose biosynthesis, procollagen hydroxylation and glycosylation, protein O-glycosylation (Neisseria), protein Pupylation and dePupylation, protein S-nitrosylation and denitrosylation, protein SAMPylation and SAMP-mediated thiolation, protein ubiquitination, purine deoxyribonucleosides degradation I, purine deoxyribonucleosides degradation II, purine nucleobases degradation I (anaerobic), purine nucleobases degradation II (anaerobic), purine ribonucleosides degradation, pyoverdine I biosynthesis, pyrrolnitrin biosynthesis, pyrroloquinoline quinone biosynthesis, pyruvate fermentation to (R)-acetoin I, pyruvate fermentation to (S)-acetoin, queuosine biosynthesis I (de novo), queuosine biosynthesis III (queuosine salvage), quinoxaline-2-carboxylate biosynthesis, rifamycin B biosynthesis, roseoflavin biosynthesis, rotenoid biosynthesis I, rotenoid biosynthesis II, roxarsone (and nitarsone) degradation III, roxarsone degradation I, S-methyl-5'-thioadenosine degradation III, salicin biosynthesis, salicortin biosynthesis, saliniketal A biosynthesis, salinosporamide A biosynthesis, sarcinaxanthin diglucoside biosynthesis, seleno-amino acid detoxification and volatilization II, seleno-amino acid detoxification and volatilization III, sesaminol glucoside biosynthesis, sesquiterpenoid phytoalexins biosynthesis, shikonin biosynthesis, sitosterol degradation to androstenedione, solasodine and soladulcidine biosynthesis, sorgoleone biosynthesis, spectinabilin biosynthesis, spheroidene and spheroidenone biosynthesis, spirilloxanthin and 2,2'-diketo-spirilloxanthin biosynthesis, staphyloxanthin biosynthesis, staurosporine biosynthesis, sterculate biosynthesis, sterigmatocystin biosynthesis, streptomycin biosynthesis, streptorubin B biosynthesis, streptovaricin biosynthesis, streptozotocin biosynthesis, sulfolactate degradation II, sulfolactate degradation III, sulfur oxidation IV (intracellular sulfur), superpathway of phylloquinol biosynthesis, superpathway of sulfide oxidation (Acidithiobacillus ferrooxidans), synechoxanthin biosynthesis, taurine degradation II, terminal olefins biosynthesis II, terrequinone A biosynthesis, testosterone and androsterone degradation to androstendione (aerobic), testosterone degradation (anaerobic), tetrachloroethene degradation, tetrahydromethanopterin biosynthesis, tetrathionate reduction I (to thiosulfate), thiamine phosphate formation from pyrithiamine and oxythiamine (yeast), thiazole component of thiamine diphosphate biosynthesis II, thiazole component of thiamine diphosphate biosynthesis III, thioredoxin pathway, thiosulfate oxidation II (via tetrathionate), thyroid hormone biosynthesis, thyroid hormone metabolism I (via deiodination), thyroid hormone metabolism II (via conjugation and/or degradation), thyronamine and iodothyronamine metabolism, trans-4-hydroxy-L-proline degradation II, trans-lycopene biosynthesis I, trans-zeatin biosynthesis, tRNA-uridine 2-thiolation (cytoplasmic), tRNA-uridine 2-thiolation (mammalian mitochondria), tRNA-uridine 2-thiolation (thermophilic bacteria), tRNA-uridine 2-thiolation (yeast mitochondria), tRNA-uridine 2-thiolation and selenation (bacteria), ubiquinol-10 biosynthesis (early decarboxylation), ubiquinol-10 biosynthesis (late decarboxylation), ubiquinol-6 biosynthesis (late decarboxylation), ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast), ubiquinol-7 biosynthesis (early decarboxylation), ubiquinol-7 biosynthesis (late decarboxylation), ubiquinol-8 biosynthesis (early decarboxylation), ubiquinol-8 biosynthesis (late decarboxylation), ubiquinol-9 biosynthesis (early decarboxylation), ubiquinol-9 biosynthesis (late decarboxylation), uracil degradation II (oxidative), urate conversion to allantoin III, validamycin biosynthesis, vindoline, vindorosine and vinblastine biosynthesis, vitamin B6 degradation I, vitamin B6 degradation II, xanthommatin biosynthesis, zealexin biosynthesis more

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Roles as Enzyme Ligand

In Vivo Product in Enzyme-catalyzed Reactions (2 results)

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Show Natural Product (2 entries)

EC NUMBER

PROVEN IN VIVO REACTION

REACTION DIAGRAM

LITERATURE

ENZYME 3D STRUCTURE

2.4.2.6

purine base + 2-deoxy-D-ribosyl-base = purine deoxyribonucleoside + base

0

-

2.4.2.6

pyrimidine base + 2-deoxy-D-ribosyl-base = pyrimidine deoxyribonucleoside + base

0

-

2.4.2.6

2 entries

Substrate in Enzyme-catalyzed Reactions (6 results)

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Show Substrate (6 entries)

EC NUMBER

REACTION

REACTION DIAGRAM

LITERATURE

ENZYME 3D STRUCTURE

2.4.2.6

dAMP + base = dNMP + adenine

674900

-

2.4.2.6

dCMP + base = dNMP + cytidine

674900

-

2.4.2.6

dGMP + base = dNMP + guanine

674900

-

2.4.2.6

dIMP + base = dNMP + hypoxanthine

674900

-

2.4.2.6

dTMP + base = dNMP + thymine

674900

-

2.4.2.6

dUMP + base = dNMP + uracil

674900

-

2.4.2.6

6 entries

Product in Enzyme-catalyzed Reactions (2 results)

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Show Product (2 entries)

EC NUMBER

REACTION

REACTION DIAGRAM

LITERATURE

ENZYME 3D STRUCTURE

2.4.2.6

purine base + 2-deoxy-D-ribosyl-base = purine deoxyribonucleoside + base

0

-

2.4.2.6

pyrimidine base + 2-deoxy-D-ribosyl-base = pyrimidine deoxyribonucleoside + base

0

-

2.4.2.6

2 entries

Enzyme Kinetic Parameters

References & Links

Literature References (1)

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Show Reference (1 entry)

BRENDA REFERENCE ID

PUBMED ID

TITLE

YEAR

AUTHORS

JOURNAL

VOLUME

PAGES

674900

17234634

The c-Myc target gene Rcl (C6orf108) encodes a novel enzyme, deoxynucleoside 5-monophosphate N-glycosidase

2007

Ghiorghi, Y.K.; Zeller, K.I.; Dang, C.V.; Kaminski, P.A.

J. Biol. Chem.

282

8150-8156

Links to other databases for base

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Show Links (1 entry)