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Information on EC 7.6.2.6 - ABC-type guanine transporter

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IUBMB Comments
An ATP-binding cassette (ABC) type transporter found in insects that transports guanine and other purines into pigment granules in the eye, where they are converted to pteridine pigments. The transporter is a hererodimer composed of two different peptides, each containing one membrane-spanning and one cytoplasmic ATP-binding domain. In Drosophila, this transporter is encoded by the white and brown genes.
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The expected taxonomic range for this enzyme is: Drosophila melanogaster
Synonyms
guanine-transporting ATPase, more
REACTION
REACTION DIAGRAM
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ORGANISM
UNIPROT
LITERATURE
ATP + H2O + guanine[side 1] = ADP + phosphate + guanine[side 2]
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ABC-type (ATP-binding cassette) ATPase. Does not undergo phosphorylation during the transport process. A bacterial enzyme that imports guanine and tryptophan (it contains a single ATP-binding site)
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