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Information on EC 7.4.2.2 - ABC-type nonpolar-amino-acid transporter

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IUBMB Comments
An ATP-binding cassette (ABC) type transporter, characterized by the presence of two similar ATP-binding domains/proteins and two integral membrane domains/proteins. The enzyme, found in bacteria, interacts with an extracytoplasmic substrate binding protein. This entry comprises enzymes that import Leu, Ile and Val.
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Word Map
The expected taxonomic range for this enzyme is: Bacteria, Eukaryota
Reaction Schemes
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nonpolar amino acid-[nonpolar amino acid-binding protein][side 1]
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nonpolar amino acid[side 2]
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[nonpolar amino acid-binding protein][side 1]
Synonyms
AAP1, ABC-type high-affinity basic amino acid uptake transporter, acidic amino acid permease, amino acid permease 1, ATB0, ATP phosphohydrolase (nonpolar-amino-acid-transporting), ATPase, AVT3, B0AT1, BCAA permease, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
ATP + H2O + nonpolar amino acid-[nonpolar amino acid-binding protein][side 1] = ADP + phosphate + nonpolar amino acid[side 2] + [nonpolar amino acid-binding protein][side 1]
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