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Information on EC 7.4.2.11 - ABC-type methionine transporter

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IUBMB Comments
ABC-type (ATP-binding cassette-type) transporter, characterized by the presence of two similar ATP-binding domains/proteins and two integral membrane domains/proteins. A bacterial enzyme that interacts with an extracytoplasmic substrate binding protein and functions to import methionine. The enzyme from Escherichia coli K-12 mediates the high affinity transport of both L- and D-methionine, as well as methionine-S-oxide and N-acetyl-DL-methionine.
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The expected taxonomic range for this enzyme is: Escherichia coli
Reaction Schemes
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L-methionine-[methionine-binding protein][side 1]
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[methionine-binding protein][side 1]
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D-methionine-[methionine-binding protein][side 1]
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[methionine-binding protein][side 1]
Synonyms
D-methionine transporter, metD, methionine ABC transporter, methionine ATP binding cassette transporter, methionine importer, methionine transporting ATPase, methionine uptake transporter, metI, metN, MetNI, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
ATP + H2O + D-methionine-[methionine-binding protein][side 1] = ADP + phosphate + D-methionine[side 2] + [methionine-binding protein][side 1]
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(2)
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ATP + H2O + L-methionine-[methionine-binding protein][side 1] = ADP + phosphate + L-methionine[side 2] + [methionine-binding protein][side 1]
show the reaction diagram
(1)
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