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Information on EC 7.4.2.10 - ABC-type glutathione transporter

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IUBMB Comments
A prokaryotic ATP-binding cassette (ABC) type transporter, characterized by the presence of two similar ATP-binding domains/proteins and two integral membrane domains/proteins. The enzyme from the bacterium Escherichia coli is a heterotrimeric complex that interacts with an extracytoplasmic substrate binding protein to mediate the uptake of glutathione.
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The expected taxonomic range for this enzyme is: Eukaryota, Bacteria
Reaction Schemes
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glutathione-[glutathione-binding protein][side 1]
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[glutathione-binding protein][side 1]
Synonyms
ABCC3(6), ABCC3-type transporter, ATM1, Bpt1p, glutathione ABC transporter, glutathione transporting ATPase, glutathione-conjugate transporter, GSI, gsiACD, MOAT3, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
ATP + H2O + glutathione-[glutathione-binding protein][side 1] = ADP + phosphate + glutathione[side 2] + [glutathione-binding protein][side 1]
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