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Information on EC - ABC-type ferric citrate transporter

for references in articles please use BRENDA:EC7.2.2.18
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EC Tree
IUBMB Comments
An ATP-binding cassette (ABC) type transporter, characterized by the presence of two similar ATP-binding domains/proteins and two integral membrane domains/proteins. The enzyme from Escherichia coli interacts with a periplasmic substrate binding protein and mediates the high affinity uptake of Fe3+-citrate in the form of a mononuclear (containing one iron(III) ion and two citrate molecules) or dinuclear (containing 2 iron(III) ions) complexes.
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The expected taxonomic range for this enzyme is: Bacteria, Eukaryota
Reaction Schemes
Fe3+-dicitrate-[dicitrate-binding protein][side 1]
[dicitrate-binding protein][side 1]
fecB, fecC, fecD, fecE, ferric citrate ABC transporter, ferric citrate transporting ATPase, fhuD, iron (III) dicitrate ABC transporter, iron dicitrate transporter, more
ATP + H2O + Fe3+-dicitrate-[dicitrate-binding protein][side 1] = ADP + phosphate + Fe3+-dicitrate[side 2] + [dicitrate-binding protein][side 1]
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