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Information on EC 7.2.2.18 - ABC-type ferric citrate transporter

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IUBMB Comments
An ATP-binding cassette (ABC) type transporter, characterized by the presence of two similar ATP-binding domains/proteins and two integral membrane domains/proteins. The enzyme from Escherichia coli interacts with a periplasmic substrate binding protein and mediates the high affinity uptake of Fe3+-citrate in the form of a mononuclear (containing one iron(III) ion and two citrate molecules) or dinuclear (containing 2 iron(III) ions) complexes.
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The enzyme appears in viruses and cellular organisms
Reaction Schemes
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Fe3+-dicitrate-[dicitrate-binding protein][side 1]
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[dicitrate-binding protein][side 1]
Synonyms
fecB, fecC, fecD, fecE, ferric citrate ABC transporter, ferric citrate transporting ATPase, fhuD, iron (III) dicitrate ABC transporter, iron dicitrate transporter, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
ATP + H2O + Fe3+-dicitrate-[dicitrate-binding protein][side 1] = ADP + phosphate + Fe3+-dicitrate[side 2] + [dicitrate-binding protein][side 1]
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