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Information on EC 7.2.2.16 - ABC-type ferric hydroxamate transporter

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IUBMB Comments
An ATP-binding cassette (ABC) type transporter, characterized by the presence of two similar ATP-binding domains/proteins and two integral membrane domains/proteins. A bacterial enzyme that interacts with an extracytoplasmic substrate binding protein and mediates the import of Fe3+-complexed hydroxamate siderophores such as coprogen, ferrichrome and the ferric hydroxamate antibiotic, albomycin.
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The enzyme appears in viruses and cellular organisms
Synonyms
alpha-amyrin 28-hydroxylase, FhuA, fhuACDB, fluB, iron(III) hydroxamate ABC transporter, iron(III) hydroxamate transporting ATPase, lupeol 28-hydroxylase, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
ATP + H2O + Fe3+-hydroxamate complex-[hydroxamate-binding protein][side 1] = ADP + phosphate + Fe3+-hydroxamate complex[side 2] + [hydroxamate-binding protein][side 1]
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