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Information on EC 7.2.2.12 - P-type Zn2+ transporter and Organism(s) Oryza sativa and UniProt Accession A3BF39

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EC Tree
IUBMB Comments
A P-type ATPase that undergoes covalent phosphorylation during the transport cycle. The enzyme, present in prokaryotes and photosynthetic eukaryotes, exports Zn2+ and the related cations Cd2+ and Pb2+.
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This record set is specific for:
Oryza sativa
UNIPROT: A3BF39
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Word Map
The taxonomic range for the selected organisms is: Oryza sativa
The expected taxonomic range for this enzyme is: Bacteria, Eukaryota
Synonyms
zinc transporter, athma4, p1b-type atpase, p1b-atpase, tchma4, zinc transporter 2, npunr4017, heavy metal atpase 2, atpase znta, zn(2+)-atpase, more
SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
heavy metal ATPase 2
E7EC32
-
HMA2
E7EC32
-
Zn(II)-translocating P-type ATPase
-
-
-
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Zn,Cd-transporting P-type ATPase
-
-
-
-
REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
hydrolysis of phosphoric ester
-
-
-
-
transmembrane transport
-
-
-
-
SYSTEMATIC NAME
IUBMB Comments
ATP phosphohydrolase (P-type, Zn2+-exporting)
A P-type ATPase that undergoes covalent phosphorylation during the transport cycle. The enzyme, present in prokaryotes and photosynthetic eukaryotes, exports Zn2+ and the related cations Cd2+ and Pb2+.
CAS REGISTRY NUMBER
COMMENTARY hide
9000-83-3
-
SOURCE TISSUE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
SOURCE
E7EC32
-
Manually annotated by BRENDA team
E7EC32
-
Manually annotated by BRENDA team
LOCALIZATION
ORGANISM
UNIPROT
COMMENTARY hide
GeneOntology No.
LITERATURE
SOURCE
GENERAL INFORMATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
malfunction
E7EC32
hma2 mutants have a significantly lower translocation ratio of Cd2+ and Zn2+ than the wild type enzyme
physiological function
E7EC32
HMA2 is not responsible for the uptake of heavy metals but is a major transporter of zinc and cadmium from roots to shoots
EXPRESSION
ORGANISM
UNIPROT
LITERATURE
there is no significant difference in HMA2 expression after Cd2+ or Zn2+ treatment
E7EC32
REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Satoh-Nagasawa, N.; Mori, M.; Nakazawa, N.; Kawamoto, T.; Nagato, Y.; Sakurai, K.; Takahashi, H.; Watanabe, A.; Akagi, H.
Mutations in rice (Oryza sativa) heavy metal ATPase 2 (OsHMA2) restrict the translocation of zinc and cadmium
Plant Cell Physiol.
53
213-224
2012
Oryza sativa (E7EC32), Oryza sativa
Manually annotated by BRENDA team