Any feedback?
Please rate this page
(enzyme.php)
(0/150)

BRENDA support

BRENDA Home
show all | hide all No of entries

Information on EC 7.2.2.10 - P-type Ca2+ transporter and Organism(s) Procambarus clarkii and UniProt Accession Q6SLH6

for references in articles please use BRENDA:EC7.2.2.10
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
EC Tree
IUBMB Comments
A P-type ATPase that undergoes covalent phosphorylation during the transport cycle. This enzyme family comprises three types of Ca2+-transporting enzymes that are found in the plasma membrane, the sarcoplasmic reticulum, in yeast, and in some bacteria. The enzymes from plasma membrane and from yeast have been shown to transport one ion per ATP hydrolysed whereas those from the sarcoplasmic reticulum transport two ions per ATP hydrolysed. In muscle cells Ca2+ is transported from the cytosol (side 1) into the sarcoplasmic reticulum (side 2).
Specify your search results
Select one or more organisms in this record: ?
This record set is specific for:
Procambarus clarkii
UNIPROT: Q6SLH6
Show additional data
Do not include text mining results
Include (text mining) results
Include results (AMENDA + additional results, but less precise)
Word Map
The taxonomic range for the selected organisms is: Procambarus clarkii
The enzyme appears in selected viruses and cellular organisms
Synonyms
serca, ca2+-atpase, serca2a, ca2+ pump, serca2, ca-atpase, calcium pump, ca2+ atpase, serca1, serca2b, more
SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
plasma membrane Ca2+ ATPase
-
ATP-dependent Ca2+ pump PMR1
-
-
-
-
ATPase 2C1
-
-
-
-
Ca2+ ATPase
-
-
-
-
Ca2+-ATPase, isoform 10
-
-
-
-
Ca2+-ATPase, isoform 11
-
-
-
-
Ca2+-ATPase, isoform 12
-
-
-
-
Ca2+-ATPase, isoform 13
-
-
-
-
Ca2+-pumping ATPase
-
-
-
-
Ca2+-transporting ATPase
-
-
-
-
calcium pump
-
-
-
-
Calcium-transporting ATPase sarcoplasmic reticulum type, fast twitch skeletal muscle isoform
-
-
-
-
Calcium-transporting ATPase sarcoplasmic reticulum type, slow twitch skeletal muscle isoform
-
-
-
-
ChkSERCA3
-
-
-
-
endoplasmic reticulum class 1/2 Ca(2+) ATPase
-
-
-
-
Golgi Ca2+-ATPase
-
-
-
-
HUSSY-28
-
-
-
-
P-type calcium ATPase
-
-
-
-
phosphatase, adenosine tri
-
-
-
-
plasma membrane Ca-ATPase
-
-
-
-
PMCA1
-
-
-
-
PMCA2
-
-
-
-
PMCA3
-
-
-
-
PMCA4
-
-
-
-
sarco(endo)plasmic reticulum Ca2+-ATPase
-
-
-
-
sarcoplasmic reticulum ATPase
-
-
-
-
Secretory pathway Ca2+ transporting ATPase
-
-
-
-
SERCA
-
-
-
-
SERCA1
-
-
-
-
SERCA2
-
-
-
-
SERCA3
-
-
-
-
Vacuolar Ca2+-ATPase
-
-
-
-
REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
hydrolysis of phosphoric ester
-
-
-
-
SYSTEMATIC NAME
IUBMB Comments
ATP phosphohydrolase (P-type, Ca2+-transporting)
A P-type ATPase that undergoes covalent phosphorylation during the transport cycle. This enzyme family comprises three types of Ca2+-transporting enzymes that are found in the plasma membrane, the sarcoplasmic reticulum, in yeast, and in some bacteria. The enzymes from plasma membrane and from yeast have been shown to transport one ion per ATP hydrolysed whereas those from the sarcoplasmic reticulum transport two ions per ATP hydrolysed. In muscle cells Ca2+ is transported from the cytosol (side 1) into the sarcoplasmic reticulum (side 2).
CAS REGISTRY NUMBER
COMMENTARY hide
9000-83-3
-
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
ATP + H2O + Ca2+/cis
ADP + phosphate + Ca2+/trans
show the reaction diagram
-
-
-
?
additional information
?
-
NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
ATP + H2O + Ca2+/cis
ADP + phosphate + Ca2+/trans
show the reaction diagram
-
-
-
?
additional information
?
-
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
red swamp crayfish
SwissProt
Manually annotated by BRENDA team
SOURCE TISSUE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
SOURCE
expression and activity during molting cycle, overview
Manually annotated by BRENDA team
expression and activity during molting cycle, overview
Manually annotated by BRENDA team
expression and activity during molting cycle, overview
Manually annotated by BRENDA team
expression and activity during molting cycle, overview
Manually annotated by BRENDA team
axial abdominal muscle, expression and activity during molting cycle, overview
Manually annotated by BRENDA team
LOCALIZATION
ORGANISM
UNIPROT
COMMENTARY hide
GeneOntology No.
LITERATURE
SOURCE
UNIPROT
ENTRY NAME
ORGANISM
NO. OF AA
NO. OF TRANSM. HELICES
MOLECULAR WEIGHT[Da]
SOURCE
SEQUENCE
LOCALIZATION PREDICTION?
Q6SLH6_PROCL
1190
6
131139
TrEMBL
other Location (Reliability: 2)
MOLECULAR WEIGHT
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
130000
x * 130000, SDS-PAGE
SUBUNIT
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
?
x * 130000, SDS-PAGE
CLONED (Commentary)
ORGANISM
UNIPROT
LITERATURE
PMCA3 DNA and amino acid sequence determination and analysis, phylogenetic tree, expression analysis during molting cycle
REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Gao, Y.; Wheatly, M.G.
Characterization and expression of plasma membrane Ca2+ ATPase (PMCA3) in the crayfish Procambarus clarkii antennal gland during molting
J. Exp. Biol.
207
2991-3002
2004
Procambarus clarkii (Q6SLH6), Procambarus clarkii
Manually annotated by BRENDA team