Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
6-phosphofructokinase deficiency
The contribution of Ca+ calmodulin activation of human erythrocyte AMP deaminase (isoform E) to the erythrocyte metabolic dysregulation of familial phosphofructokinase deficiency.
6-phosphofructokinase deficiency
The contribution of Ca2+-calmodulin activation of human erythrocyte AMP deaminase (isoform E) to the erythrocyte metabolic dysregulation of familial phosphofructokinase deficiency.
Acantholysis
Mechanisms of synergy of autoantibodies to M3 muscarinic acetylcholine receptor and secretory pathway Ca2+/Mn2+-ATPase isoform 1 in patients with non-desmoglein pemphigus vulgaris.
Acantholysis
Protein aggregation of SERCA2 mutants associated with Darier disease elicits ER stress and apoptosis in keratinocytes.
Acantholysis
Synergy among non-desmoglein antibodies contributes to the immunopathology of desmoglein antibody-negative pemphigus vulgaris.
Acantholysis
Weak immunohistochemical expression of galectin-3 near blisters in Hailey-Hailey disease.
Acantholysis
[Dyskeratosis follicularis].
Acidosis
Acidosis alters the phosphorylation of Ser16 and Thr17 of phospholamban in rat cardiac muscle.
Acidosis
Ca2+/calmodulin-dependent protein kinase: a key component in the contractile recovery from acidosis.
Acidosis
Coronary artery acidosis: pH and calcium pump stability.
Acidosis
Effect of pH on stability of sarcoplasmic reticulum calcium pump in rabbit heart.
Acidosis
Glucose 6-phosphate and fructose 1,6-bisphosphate can be used as ATP-regenerating systems by cerebellum Ca2+-transport ATPase.
Acidosis
Glycoside inotropy in the absence of an increase in potassium efflux in the rabbit heart.
Acidosis
Magnesium role in cardiovascular diseases.
Acidosis
Mechanism of acidic pH-induced contraction in spontaneously hypertensive rat aorta: role of Ca2+ release from the sarcoplasmic reticulum.
Acidosis
Monitoring Exercise-Induced Muscle Fatigue and Adaptations: Making Sense of Popular or Emerging Indices and Biomarkers.
Acidosis
Phospholamban and cardiac function: a comparative perspective in vertebrates.
Acidosis
Sarco/endoplasmic reticulum Ca2+-ATPase isoforms: diverse responses to acidosis.
Acidosis
Sodium Accumulation in SERCA Knockout-Induced Heart Failure.
Acidosis
[The mechanism of contractile dysfunction in heart failure, focussing on SERCA2a function]
Acidosis, Respiratory
Effect of respiratory acidosis and respiratory alkalosis on renal transport enzymes.
Acute Coronary Syndrome
[The immune-enzyme technique of detection of Ca2+ ATPase of sarcoplasmic reticulum--a new biologic marker of acute cardiac infarction].
Adenocarcinoma
Advanced oxidation protein products decrease the expression of calcium transport channels in small intestinal epithelium via the p44/42 MAPK signaling pathway.
Adenocarcinoma
Altered Endoplasmic Reticulum Calcium Pump Expression during Breast Tumorigenesis.
Adenocarcinoma
Expression of endomembrane calcium pumps in colon and gastric cancer cells. Induction of SERCA3 expression during differentiation.
Adenocarcinoma
Plasma Membrane Ca2+ ATPase Isoform 4 (PMCA4) Has an Important Role in Numerous Hallmarks of Pancreatic Cancer.
Adenocarcinoma
The loss of sarco/endoplasmic reticulum calcium transport ATPase 3 expression is an early event during the multistep process of colon carcinogenesis.
Adenocarcinoma of Lung
Adam17, a Target of Mir-326, Promotes Emt-Induced Cells Invasion in Lung Adenocarcinoma.
Adenocarcinoma of Lung
Modulation of endoplasmic reticulum calcium pump expression during lung cancer cell differentiation.
Adenocarcinoma of Lung
[Effect of adenomatous polyposis coli(APC) promoter methylation on gene transcription in lung cancer cell lines]
Adenocarcinoma of Lung
[Inhibitory effects of the survivin siRNA transfection on human lung adenocarcinoma cells SPCA1 and SH77].
Adenocarcinoma of Lung
[Prolonged hypoxia induces GST-pi expression and drug resistance in lung adenocarcinoma cell line SPCA1]
Adenocarcinoma of Lung
[Serophysiological study on the effects of high-fat diet on proliferation of human lung adenocarcinoma cell line SPCA1]
Adenocarcinoma of Lung
[Toxicity of arsenic trioxide to human lung adenocarcinoma cell line SPCA1 and its mechanism.]
Adenoma
Aberrant SERCA3 expression during the colorectal adenoma-adenocarcinoma sequence.
Adenoma
Plasma membrane calcium ATPase expression in human colon multistep carcinogenesis.
Adenoma
The loss of sarco/endoplasmic reticulum calcium transport ATPase 3 expression is an early event during the multistep process of colon carcinogenesis.
Adenoviridae Infections
Adenovirus-mediated gene transfer reconstitutes depressed sarcoplasmic reticulum Ca2+-ATPase levels and shortens prolonged cardiac myocyte Ca2+ transients.
Adenoviridae Infections
Regulation of expression of cardiac sarcoplasmic reticulum proteins under pathophysiological conditions.
Adrenal Insufficiency
Cardiac impairment in adrenal insufficiency in the cat. Reduced adenosinetriphosphatase activity of myocardial contractile proteins.
Albuminuria
Enhancement of intrarenal plasma membrane calcium pump isoform 1 expression in chronic angiotensin II-infused mice.
Alkalosis
Temperature and pH effects on Ca2+ sensitivity of cardiac myofibrils: a comparison of trout with mammals.
Alkalosis, Respiratory
Effect of respiratory acidosis and respiratory alkalosis on renal transport enzymes.
Altitude Sickness
Transport ATPases in the erythrocytes of rats acclimatized to intermittent altitude hypoxia.
Alzheimer Disease
A new target for Alzheimer's disease: A small molecule SERCA activator is neuroprotective in vitro and improves memory and cognition in APP/PS1 mice.
Alzheimer Disease
Altered Ca2+ dependence of synaptosomal plasma membrane Ca2+-ATPase in human brain affected by Alzheimer's disease.
Alzheimer Disease
Highly cooperative dependence of sarco/endoplasmic reticulum calcium ATPase (SERCA) 2a pump activity on cytosolic calcium in living cells.
Alzheimer Disease
Schekwanglupaside C, a new lupane saponin from Schefflera kwangsiensis, is a potent activator of sarcoplasmic reticulum Ca2+-ATPase.
Alzheimer Disease
SERCA pump activity is physiologically regulated by presenilin and regulates amyloid beta production.
Alzheimer Disease
The endoplasmic reticulum Ca2+ -ATPase SERCA2b is upregulated in activated microglia and its inhibition causes opposite effects on migration and phagocytosis.
Anemia
Biochemical changes associated with the osmotic fragility of young and mature erythrocytes caused by parathyroid hormone in relation to the uremic syndrome.
Anemia
Effect of parathyroid hormone on the fragility and enzyme activities of red blood cells from young and mature rabbits.
Anemia
Iron deficiency anemia reduces cardiac contraction by downregulating RyR2 channels and suppressing SERCA pump activity.
Anemia
The enzymes of the red blood cell plasma membrane.
Anemia, Iron-Deficiency
Iron deficiency anemia reduces cardiac contraction by downregulating RyR2 channels and suppressing SERCA pump activity.
Anemia, Sickle Cell
[Erythrocyte membrane proteins]
Anthrax
Novel aspects of calmodulin target recognition and activation.
Aortic Aneurysm
Inactivation of cysteine 674 in the SERCA2 accelerates experimental aortic aneurysm.
Aortic Aneurysm
Inactivation of SERCA2 Cys674 accelerates aortic aneurysms by suppressing PPAR?.
Aortic Coarctation
Na,K-ATPase and Ca-ATPase activities of the myocardial sarcolemma in aging rats after aorta coarctation: role of invertors.
Aortic Stenosis, Supravalvular
Importance of SERCA2a on early isolated diastolic dysfunction induced by supravalvular aortic stenosis in rats.
Aortic Valve Stenosis
Transgenic expression of sarcoplasmic reticulum Ca(2+) atpase modifies the transition from hypertrophy to early heart failure.
Arrhythmias, Cardiac
Calcium extrusion is critical for cardiac morphogenesis and rhythm in embryonic zebrafish hearts.
Arrhythmias, Cardiac
Carbon monoxide exposure enhances arrhythmia after cardiac stress: involvement of oxidative stress.
Arrhythmias, Cardiac
Dispersion of ventricular mRNA of RyR2 and SERCA2 associated with arrhythmogenesis in rats.
Arrhythmias, Cardiac
Dyssynchronous calcium removal in heart failure-induced atrial remodeling.
Arrhythmias, Cardiac
E3 Ubiquitin ligase NEDD4 family?regulatory network in cardiovascular disease.
Arrhythmias, Cardiac
Effect of age and sex on the incidence of ventricular arrhythmia in a rat model of acute ischemia.
Arrhythmias, Cardiac
Endothelin receptor antagonist CPU0213 and vitamin E reverse downregulation of FKBP12.6 and SERCA2a: a role of hyperphosphorylation of PKCepsilon.
Arrhythmias, Cardiac
Exposure to low-level metalaxyl impacts the cardiac development and function of zebrafish embryos.
Arrhythmias, Cardiac
Improved systolic function of rat cardiocytes during heart failure by overexpression of SERCA2a.
Arrhythmias, Cardiac
Ion channelopathy and hyperphosphorylation contributing to cardiac arrhythmias.
Arrhythmias, Cardiac
PMCA4 inhibition does not affect cardiac remodelling following myocardial infarction, but may reduce susceptibility to arrhythmia.
Arrhythmias, Cardiac
SERCA in genesis of arrhythmias: what we already know and what is new?
Arrhythmias, Cardiac
Two patterns of ion channelopathy in the myocardium: perspectives for development of anti-arrhythmic agents.
Arthritis
Ca2+ signalling plays a role in celastrol-mediated suppression of synovial fibroblasts of rheumatoid arthritis patients and experimental arthritis in rats.
Arthritis, Experimental
Modulation of SERCA in the chronic phase of adjuvant arthritis as a possible adaptation mechanism of redox imbalance.
Arthritis, Experimental
Oxidative impairment of plasma and skeletal muscle sarcoplasmic reticulum in rats with adjuvant arthritis - effects of pyridoindole antioxidants.
Asthenozoospermia
Plasma membrane Ca2+-ATPase 4: interaction with constitutive nitric oxide synthases in human sperm and prostasomes which carry Ca2+/CaM-dependent serine kinase.
Asthenozoospermia
Sperm Na(+), K(+)-ATPase ?4 and plasma membrane Ca(2+)-ATPase (PMCA) 4 regulation in asthenozoospermia.
Asthma
Chromosome 17q21 Genes ORMDL3 and GSDMB in Asthma and Immune Diseases.
Asthma
Decreased sodium-potassium and calcium adenosine triphosphatase activity in asthma: modulation by inhaled and oral corticosteroids.
Asthma
Diminished sarco/endoplasmic reticulum Ca2+ ATPase (SERCA) expression contributes to airway remodelling in bronchial asthma.
Asthma
Increased intracellular calcium and decreased activities of leucocyte Na+,K+-ATPase and Ca2+-ATPase in asthma.
Asthma
ORMDL3 is an inducible lung epithelial gene regulating metalloproteases, chemokines, OAS, and ATF6.
Asthma
ORMDL3 Transgenic Mice Have Increased Airway Remodeling and Airway Responsiveness Characteristic of Asthma.
Asthma
Reduced sarcoplasmic reticulum Ca2+ ATPase activity underlies skeletal muscle wasting in asthma.
Asthma
The effect of substance P on asthmatic rat airway smooth muscle cell proliferation, migration, and cytoplasmic calcium concentration in vitro.
Asthma
[Activity of sodium-potassium adenosinetriphosphatase and cotransport of sodium, potassium and chloride ions in patients with bronchial asthma and chronic obstructive pulmonary diseases]
Astrocytoma
Histamine-induced calcium mobilization in single cultured cells expressing histamine H1 receptors: a relationship between its sensitivity and the density of H1 receptors.
Ataxia
A de novo deafwaddler mutation of Pmca2 arising in ES cells and hitchhiking with a targeted modification of the Pparg gene.
Ataxia
A novel PMCA3 mutation in an ataxic patient with hypomorphic phosphomannomutase 2 (PMM2) heterozygote mutations: Biochemical characterization of the pump defect.
Ataxia
A V1143F mutation in the neuronal-enriched isoform 2 of the PMCA pump is linked with ataxia.
Ataxia
Calcium pumps of plasma membrane and cell interior.
Ataxia
Enhanced Synaptic Inhibition in the Cerebellar Cortex of the Ataxic PMCA2(-/-) Knockout Mouse.
Ataxia
Haplo-insufficiency revealed in deafwaddler mice when tested for hearing loss and ataxia.
Ataxia
Insertion of an intracisternal A particle retrotransposon element in plasma membrane calcium ATPase 2 gene attenuates its expression and produces an ataxic phenotype in joggle mutant mice.
Ataxia
Low endolymph calcium concentrations in deafwaddler2J mice suggest that PMCA2 contributes to endolymph calcium maintenance.
Ataxia
The Effect of Passive Movement on Denervated Soleus Highlights a Differential Nerve Control on SERCA and MyHC Isoforms.
Ataxia
The plasma membrane calcium pump in health and disease.
Atherosclerosis
Activation of AMP-activated Protein Kinase Inhibits oxidized Low Density Lipoprotein-triggered Endoplasmic Reticulum (ER) Stress in vivo.
Atherosclerosis
Altered vascular smooth muscle function in the ApoE knockout mouse during the progression of atherosclerosis.
Atherosclerosis
E3 Ubiquitin ligase NEDD4 family?regulatory network in cardiovascular disease.
Atherosclerosis
S-Glutathiolation by peroxynitrite activates SERCA during arterial relaxation by nitric oxide.
Atherosclerosis
Targeting the redox regulation of SERCA in vascular physiology and disease.
Atrial Fibrillation
Angiotensin II does not influence expression of sarcoplasmic reticulum Ca2 + ATPase in atrial myocytes.
Atrial Fibrillation
Effect of SERCA2a overexpression in the pericardium mediated by the AAV1 gene transfer on rapid atrial pacing in rabbits.
Atrial Fibrillation
Modulation of SERCA in Patients with Persistent Atrial Fibrillation Treated by Epicardial Thoracoscopic Ablation: The CAMAF Study.
Atrial Fibrillation
Myocardial Expression of SERCA2a and Structural and Functional Indices in Patients with Atrial Fibrillation.
Atrial Fibrillation
Myocardial gene expression alterations in peripheral blood mononuclear cells of patients with idiopathic dilated cardiomyopathy.
Atrial Fibrillation
Prevention of Atrial Fibrillation by Using Sarcoplasmic Reticulum Calcium ATPase Pump Overexpression in a Rabbit Model of Rapid Atrial Pacing.
Atrial Fibrillation
Regulation of calcium pump through Notch/Jagged/Hes signaling pathway in canine model of chronic atrial fibrillation.
Atrioventricular Block
Increased cardiac adenylyl cyclase expression is associated with increased survival after myocardial infarction.
Blindness
The effect of glucose and calcium on Ca2+-adenosine triphosphatase in pancreatic islets isolated from a normal and a non-insulin-dependent diabetes mellitus rat model.
Blister
A calcium conducting channel akin to a calcium pump.
Blister
Diseases involving the Golgi calcium pump.
Blister
Identification of the cardiac ryanodine receptor channel in membrane blebs of sarcoplasmic reticulum.
Blister
Weak immunohistochemical expression of galectin-3 near blisters in Hailey-Hailey disease.
Bradycardia
Ca(2+)-Clock-Dependent Pacemaking in the Sinus Node Is Impaired in Mice with a Cardiac Specific Reduction in SERCA2 Abundance.
Bradycardia
SERCA2a was serotonylated and may regulate sino-atrial node pacemaker activity.
Brain Diseases
Chronic but not acute pharmacological activation of SERCA induces behavioral and neurochemical effects in male and female mice.
Brain Edema
THE RELATIONSHIP BETWEEN ADENOSINETRIPHOSPHATASE ACTIVITY AND TRIETHYLTIN TOXICITY IN THE PRODUCTION OF CEREBRAL EDEMA OF THE RAT.
Brain Edema
Ultracytochemical study of capillary Ca2+-ATPase activity in brain edema.
Brain Ischemia
Cerebral ischemia elicits aberration in myocardium contractile function and intracellular calcium handling.
Brain Ischemia
Changes in IP3R1 and SERCA2b mRNA levels in the gerbil brain after chronic ethanol administration and transient cerebral ischemia-reperfusion.
Brain Ischemia
Cleavage of the plasma membrane Na+/Ca2+ exchanger in excitotoxicity.
Brain Ischemia
Molecular pathways of protein synthesis inhibition during brain reperfusion: implications for neuronal survival or death.
Brain Ischemia
Ultracytochemical study of Ca2+-ATPase activity in isolated, superoxide-treated rat brains.
Breast Neoplasms
A Ca2+-ATPase Regulates E-cadherin Biogenesis and Epithelial-Mesenchymal Transition in Breast Cancer Cells.
Breast Neoplasms
An N-terminal Ca2+-binding motif regulates the secretory pathway Ca2+/Mn2+-transport ATPase SPCA1.
Breast Neoplasms
ATP2A3 gene as an important player for resveratrol anticancer activity in breast cancer cells.
Breast Neoplasms
Differential expression of PMCA2 mRNA isoforms in a cohort of Spanish patients with breast tumor types.
Breast Neoplasms
Disruption of the interaction between PMCA2 and calcineurin triggers apoptosis and enhances paclitaxel-induced cytotoxicity in breast cancer cells.
Breast Neoplasms
Distinct Regulation of Cytoplasmic Calcium Signals and Cell Death Pathways by Different Plasma Membrane Calcium ATPase Isoforms in MDA-MB-231 Breast Cancer Cells.
Breast Neoplasms
Down-Regulation of Store-Operated Ca2+ Entry and Na+ Ca2+ Exchange in MCF-7 Breast Cancer Cells by Pharmacological JAK3 Inhibition.
Breast Neoplasms
Epigenetic Modulation of SPCA2 Reverses Epithelial to Mesenchymal Transition in Breast Cancer Cells.
Breast Neoplasms
Expression of calcium pumps is differentially regulated by histone deacetylase inhibitors and estrogen receptor alpha in breast cancer cells.
Breast Neoplasms
Expression of plasma membrane calcium pump isoform mRNAs in breast cancer cell lines.
Breast Neoplasms
Histone Deacetylase Inhibitor Treatment Increases the Expression of the Plasma Membrane Ca(2+) Pump PMCA4b and Inhibits the Migration of Melanoma Cells Independent of ERK.
Breast Neoplasms
Histone deacetylase inhibitor- and PMA-induced upregulation of PMCA4b enhances Ca2+ clearance from MCF-7 breast cancer cells.
Breast Neoplasms
Histone deacetylase inhibitors promote ATP2A3 gene expression in hepatocellular carcinoma cells: p300 as a transcriptional regulator.
Breast Neoplasms
Inhibition of ezrin causes PKC?-mediated internalization of erbb2/HER2 tyrosine kinase in breast cancer cells.
Breast Neoplasms
NHERF1 Is Required for Localization of PMCA2 and Suppression of Early Involution in the Female Lactating Mammary Gland.
Breast Neoplasms
Plasma membrane Ca2+-ATPase expression during colon cancer cell line differentiation.
Breast Neoplasms
Plasma membrane calcium ATPase isoform 4 inhibits vascular endothelial growth factor-mediated angiogenesis through interaction with calcineurin.
Breast Neoplasms
Plasma membrane calcium-ATPase 2 and 4 in human breast cancer cell lines.
Breast Neoplasms
PMCA2 regulates apoptosis during mammary gland involution and predicts outcome in breast cancer.
Breast Neoplasms
PMCA2 regulates HER2 protein kinase localization and signaling and promotes HER2-mediated breast cancer.
Breast Neoplasms
PMCA2 silencing potentiates MDA-MB-231 breast cancer cell death initiated with the Bcl-2 inhibitor ABT-263.
Breast Neoplasms
SPCA2 regulates Orai1 trafficking and store independent Ca2+ entry in a model of lactation.
Breast Neoplasms
Store-independent activation of Orai1 by SPCA2 in mammary tumors.
Breast Neoplasms
Subtype specific targeting of calcium signaling in breast cancer.
Breast Neoplasms
Thapsigargin, Inhibitor of Sarco-Endoplasmic Ca2+-ATPase, Effectively Suppresses the Expression of S100A4 Protein in Human Breast Cancer Cell Line.
Breast Neoplasms
The calcium pump plasma membrane Ca(2+)-ATPase 2 (PMCA2) regulates breast cancer cell proliferation and sensitivity to doxorubicin.
Breast Neoplasms
The Golgi calcium pump secretory pathway calcium ATPase 1 (SPCA1) is a key regulator of insulin-like growth factor receptor (IGF1R) processing in the basal-like breast cancer cell line MDA-MB-231.
Breast Neoplasms
The interaction between endogenous calcineurin and the plasma membrane calcium-dependent ATPase is isoform specific in breast cancer cells.
Breast Neoplasms
The N and C-termini of SPCA2 regulate differently Kv10.1 function: role in the collagen 1-induced breast cancer cell survival.
Breast Neoplasms
The Plasma Membrane Ca2+ Pump PMCA4b Regulates Melanoma Cell Migration through Remodeling of the Actin Cytoskeleton.
Breast Neoplasms
The scaffolding protein NHERF1 regulates the stability and activity of the tyrosine kinase HER2.
Burkitt Lymphoma
Modulation of B-cell endoplasmic reticulum calcium homeostasis by Epstein-Barr virus latent membrane protein-1.
Calcinosis
Secretory pathway Ca(2+) -ATPases promote in vitro microcalcifications in breast cancer cells.
calpain-3 deficiency
Calpain 3 deficiency affects SERCA expression and function in the skeletal muscle.
Carcinogenesis
Aberrant SERCA3 expression during the colorectal adenoma-adenocarcinoma sequence.
Carcinogenesis
Aberrant SERCA3 expression is closely linked to pathogenesis, invasion, metastasis, and prognosis of gastric carcinomas.
Carcinogenesis
Adenosinetriphosphatase study during rat liver damage. II. ATP-ase activity of rat liver during 4-dimethylaminoazobenzene carcinogenesis.
Carcinogenesis
Altered Endoplasmic Reticulum Calcium Pump Expression during Breast Tumorigenesis.
Carcinogenesis
Endoplasmic reticulum calcium pumps and cancer.
Carcinogenesis
Expression of plasma membrane calcium pump isoform mRNAs in breast cancer cell lines.
Carcinogenesis
Herpesviral G protein-coupled receptors activate NFAT to induce tumor formation via inhibiting the SERCA calcium ATPase.
Carcinogenesis
Intracellular calcium pool emptying induces DNA synthesis in HaCaT keratinocytes.
Carcinogenesis
Novel allelic mutations in murine Serca2 induce differential development of squamous cell tumors.
Carcinogenesis
Pathogenic roles of altered calcium channels and transporters in colon tumorogenesis.
Carcinogenesis
Plasma membrane Ca2+ ATPase isoform 1 down-regulated in human oral cancer.
Carcinogenesis
Plasma membrane Ca2+-ATPase expression during colon cancer cell line differentiation.
Carcinogenesis
Plasma membrane Ca2+-permeable channels and sodium/calcium exchangers in tumorigenesis and tumor development of the upper gastrointestinal tract.
Carcinogenesis
Plasma membrane calcium ATPase expression in human colon multistep carcinogenesis.
Carcinogenesis
The loss of sarco/endoplasmic reticulum calcium transport ATPase 3 expression is an early event during the multistep process of colon carcinogenesis.
Carcinogenesis
[Expression of SERCA pumps during cell differentiation and tumorigenesis: application to colonic carcinogenesis]
Carcinoma
Aberrant SERCA3 expression during the colorectal adenoma-adenocarcinoma sequence.
Carcinoma
Aberrant SERCA3 expression is closely linked to pathogenesis, invasion, metastasis, and prognosis of gastric carcinomas.
Carcinoma
Activation of calcium entry in human carcinoma A431 cells by store depletion and phospholipase C- dependent mechanisms converge on ICRAC-like calcium channels.
Carcinoma
Artemisinin induces doxorubicin resistance in human colon cancer cells via calcium-dependent activation of HIF-1alpha and P-glycoprotein overexpression.
Carcinoma
Calcium, calcium-ATPase and cyclic AMP changes in Ehrlich ascites cells submitted to hyperthermia.
Carcinoma
Changes of adenosinetriphosphatase (ATPase) activities in lymphocytes from patients with carcinomas of the gastrointestinal tract.
Carcinoma
Endoplasmic reticulum calcium transport ATPase expression during differentiation of colon cancer and leukaemia cells.
Carcinoma
Epigenetic regulation of the human ATP2A3 gene promoter in gastric and colon cancer cell lines.
Carcinoma
Expression of endomembrane calcium pumps in colon and gastric cancer cells. Induction of SERCA3 expression during differentiation.
Carcinoma
Gene expression profiles of luteal phase fallopian tube epithelium from BRCA mutation carriers resemble high-grade serous carcinoma.
Carcinoma
Loss of RhoA expression prevents proliferation and metastasis of SPCA1 lung cancer cells in vitro.
Carcinoma
Novel allelic mutations in murine Serca2 induce differential development of squamous cell tumors.
Carcinoma
Plasma membrane Ca2+ ATPase isoform 1 down-regulated in human oral cancer.
Carcinoma
Plasma membrane calcium ATPase (PMCA4): A housekeeper for RT-PCR relative quantification of polytopic membrane proteins.
Carcinoma
Plasma membrane calcium ATPase expression in human colon multistep carcinogenesis.
Carcinoma
Purification and characterization of the Ca2+-ATPase of plasma membranes from Ehrlich ascites mammary carcinoma cells.
Carcinoma
RhoA inhibits apoptosis and increases proliferation of cultured SPCA1 lung cancer cells.
Carcinoma
Selective upregulation of the expression of plasma membrane calcium ATPase isoforms upon differentiation and 1,25(OH)2D3-vitamin treatment of colon cancer cells.
Carcinoma
The store-operated calcium entry pathways in human carcinoma A431 cells: functional properties and activation mechanisms.
Carcinoma
Tumor-derived vascular endothelial growth factor (VEGF)-A facilitates tumor metastasis through the VEGF-VEGFR1 signaling pathway.
Carcinoma
Ultraviolet Radiation-Induced Downregulation of SERCA2 Mediates Activation of NLRP3 Inflammasome in Basal Cell Carcinoma.
Carcinoma
[Adenosinetriphosphatase, 5-nucleotidase and alkaline phosphatase in the connective tissue of carcinoma including a contribution to the differentiation of carcinoma.]
Carcinoma
[Comparison of the adenosinetriphosphatase activity of the mitochondria of Guerin's T-8 epithelioma and of the rat liver.]
Carcinoma, Basal Cell
Ultraviolet Radiation-Induced Downregulation of SERCA2 Mediates Activation of NLRP3 Inflammasome in Basal Cell Carcinoma.
Carcinoma, Ductal
Altered Endoplasmic Reticulum Calcium Pump Expression during Breast Tumorigenesis.
Carcinoma, Ehrlich Tumor
Calcium metabolism in Ehrlich Ascites tumour cells.
Carcinoma, Ehrlich Tumor
[Adenosinetriphosphatase activity of nuclear envelopes and from the cells of rat liver, Zaigdel hepatoma of rats and Ehrlich ascites tumour of mice]
Carcinoma, Hepatocellular
A high-affinity (Ca2+ + Mg2+)-ATPase in plasma membranes of rat ascites hepatoma AH109A cells.
Carcinoma, Hepatocellular
A stress-inducible rat liver endoplasmic reticulum protein, ERp29.
Carcinoma, Hepatocellular
Fine structure and surface adenosinetriphosphatase activity of a human hepatoma.
Carcinoma, Hepatocellular
Intracellular distribution of enzymes. VII. The distribution of nucleic acids and adenosinetriphosphatase in normal mouse liver and mouse hepatoma.
Carcinoma, Hepatocellular
Intracellular distribution of enzymes; the distribution of succinic dehydrogenase, cytochrome oxidase, adenosinetriphosphatase, and phosphorus compounds in normal rat liver and in rat hepatomas.
Carcinoma, Hepatocellular
Isolation and characterization of the plasma membranes from rat ascites hepatomas and from normal rat livers, including newborn, regenerating, and adult livers.
Carcinoma, Hepatocellular
Role of G protein beta gamma subunits in the regulation of the plasma membrane Ca2+ pump.
Carcinoma, Hepatocellular
[Adenosinetriphosphatase activity of nuclear envelopes and from the cells of rat liver, Zaigdel hepatoma of rats and Ehrlich ascites tumour of mice]
Carcinoma, Hepatocellular
[Change in prostaglandin levels and ATPase activity of cardiac membrane fractions during the formation of cerebral hematomas in animals with a hereditary predisposition to stroke]
Carcinoma, Lobular
Altered Endoplasmic Reticulum Calcium Pump Expression during Breast Tumorigenesis.
Carcinoma, Non-Small-Cell Lung
Chemotherapy resistance research of lung cancer based on micro-fluidic chip system with flow medium.
Carcinoma, Squamous Cell
Novel allelic mutations in murine Serca2 induce differential development of squamous cell tumors.
Cardiac Output, Low
Combining SERCA2a activation and Na-K ATPase inhibition: a promising new approach to managing acute heart failure syndromes with low cardiac output.
Cardiomegaly
A SERCA2 pump with an increased Ca2+ affinity can lead to severe cardiac hypertrophy, stress intolerance and reduced life span.
Cardiomegaly
Ablation of phospholamban and sarcolipin results in cardiac hypertrophy and decreased cardiac contractility.
Cardiomegaly
Adeno-associated virus-mediated expression of thyroid hormone receptor isoforms-alpha1 and -beta1 improves contractile function in pressure overload-induced cardiac hypertrophy.
Cardiomegaly
Altered force-frequency response in non-failing hearts with decreased SERCA pump-level.
Cardiomegaly
An updated role of astragaloside IV in heart failure.
Cardiomegaly
Calcium regulatory proteins and their alteration by transgenic approaches.
Cardiomegaly
Cardiac hypertrophy and thyroid hormone signaling.
Cardiomegaly
Cardiac-specific overexpression of a high Ca2+ affinity mutant of SERCA2a attenuates in vivo pressure overload cardiac hypertrophy.
Cardiomegaly
Compromised Myocardial Energetics in Hypertrophied Mouse Hearts Diminish the Beneficial Effect of Overexpressing SERCA2a.
Cardiomegaly
Cyclic stretch down-regulates calcium transporter gene expression in neonatal rat ventricular myocytes.
Cardiomegaly
Differences between the effects of thyroxine and tetraiodothyroacetic acid on TSH suppression and cardiac hypertrophy.
Cardiomegaly
Doxycycline inducible expression of SERCA2a improves calcium handling and reverts cardiac dysfunction in pressure overload-induced cardiac hypertrophy.
Cardiomegaly
E3 Ubiquitin ligase NEDD4 family?regulatory network in cardiovascular disease.
Cardiomegaly
Effects of combination of irbesartan and perindopril on calcineurin expression and sarcoplasmic reticulum Ca(2+)-ATPase activity in rat cardiac pressure-overload hypertrophy.
Cardiomegaly
Effects of mild cardiac hypertrophy, induced by volume overload in turkeys, on myocardial sarcoplasmic reticulum calcium-pump and calcium-channel activities and on the creatine kinase system.
Cardiomegaly
Endurance training restores spatially distinct cardiac mitochondrial function and myocardial contractility in ovariectomized rats.
Cardiomegaly
Expression of sarcoplasmic reticulum Ca2+ -ATPase mRNA in the hypertrophied heart of young spontaneously hypertensive rats.
Cardiomegaly
Extracellular signal-regulated kinase activation during cardiac hypertrophy reduces sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (SERCA2) transcription.
Cardiomegaly
Functional polymorphism of the renalase gene is associated with cardiac hypertrophy in female patients with aortic stenosis.
Cardiomegaly
Hemodynamics and mitochondrial energy metabolism in right heart hypertrophy after acute hypoxic stress.
Cardiomegaly
Increased active elastic stiffness in tetanized papillary muscles from hypertrophied rabbit hearts.
Cardiomegaly
Interleukin-6-induced reciprocal expression of SERCA and natriuretic peptides mRNA in cultured rat ventricular myocytes.
Cardiomegaly
Isoenzyme-selective regulation of SERCA2 gene expression by protein kinase C in neonatal rat ventricular myocytes.
Cardiomegaly
Left ventricular diastolic dysfunction in Nrf2 knock out mice is associated with cardiac hypertrophy, decreased expression of SERCA2a, and preserved endothelial function.
Cardiomegaly
Left ventricular mechanical and energetic changes in long-term isoproterenol-induced hypertrophied hearts of SERCA2a transgenic rats.
Cardiomegaly
Long-term treatment with kefir probiotics ameliorates cardiac function in spontaneously hypertensive rats.
Cardiomegaly
Low density lipoprotein receptor-related protein 1 regulates cardiac hypertrophy induced by pressure overload.
Cardiomegaly
MicroRNA-328 as a regulator of cardiac hypertrophy.
Cardiomegaly
Modulation of gene expression in transgenic mouse hearts overexpressing calsequestrin.
Cardiomegaly
Molecular and functional signature of heart hypertrophy during pregnancy.
Cardiomegaly
Molecular changes in the early phase of renin-dependent cardiac hypertrophy in hypertensive cyp1a1ren-2 transgenic rats.
Cardiomegaly
Molecular cloning and analysis of the human cardiac sarco(endo)plasmic reticulum Ca(2+)-ATPase (SERCA2) gene promoter.
Cardiomegaly
Nanoscale reorganization of sarcoplasmic reticulum in pressure-overload cardiac hypertrophy visualized by dSTORM.
Cardiomegaly
On the mechanism of the reduction by thyroid hormone of beta-adrenergic relaxation rate stimulation in rat heart.
Cardiomegaly
Overexpression of junctate induces cardiac hypertrophy and arrhythmia via altered calcium handling.
Cardiomegaly
Phorbol myristate acetate-induced hypertrophy of neonatal rat cardiac myocytes is associated with decreased sarcoplasmic reticulum Ca2+ ATPase (SERCA2) gene expression and calcium reuptake.
Cardiomegaly
Phosphorylation and binding of AUF1 to the 3'-untranslated region of cardiomyocyte SERCA2a mRNA.
Cardiomegaly
Plasma membrane Ca2+-ATPase isoform 4 antagonizes cardiac hypertrophy in association with calcineurin inhibition in rodents.
Cardiomegaly
Programmed Cell Death 5 Provides Negative Feedback on Cardiac Hypertrophy Through the Stabilization of Sarco/Endoplasmic Reticulum Ca2+-ATPase 2a Protein.
Cardiomegaly
Prolonged administration of a dithiol antioxidant protects against ventricular remodeling due to ischemia-reperfusion in mice.
Cardiomegaly
Propranolol and verapamil inhibit mRNA expression of RyR2 and SERCA in L-thyroxin-induced rat ventricular hypertrophy.
Cardiomegaly
Prostaglandin F2alpha inhibits SERCA2 gene transcription through an induction of Egr-1 in cultured neonatal rat cardiac myocytes.
Cardiomegaly
Reduced myocardial sarcoplasmic reticulum Ca(2+)-ATPase protein expression in compensated primary and secondary human cardiac hypertrophy.
Cardiomegaly
Regulation of phospholamban and sarcoplasmic reticulum Ca2+-ATPase by atorvastatin: implication for cardiac hypertrophy.
Cardiomegaly
Regulation of sarco(endo)plasmic reticulum Ca(2+)-ATPase and calsequestrin gene expression in the heart.
Cardiomegaly
Regulation of sarco(endo)plasmic reticulum Ca2+ adenosine triphosphatase by phospholamban and sarcolipin: implication for cardiac hypertrophy and failure.
Cardiomegaly
Regulation of the sarcoplasmic reticulum Ca2+-ATPase expression in the hypertrophic and failing heart.
Cardiomegaly
Regulation of thyroid hormone receptor isoforms in physiological and pathological cardiac hypertrophy.
Cardiomegaly
Restoration of calcium handling properties of adult cardiac myocytes from hypertrophied hearts.
Cardiomegaly
Resveratrol ameliorates cardiac dysfunction induced by pressure overload in rats via structural protection and modulation of Ca 2+ cycling proteins.
Cardiomegaly
Sarcoplasmic reticulum Ca2+ pumps in heart and diaphragm of cardiomyopathic hamster: effects of perindopril.
Cardiomegaly
Sarcoplasmic reticulum gene expression in pressure overload-induced cardiac hypertrophy in rabbit.
Cardiomegaly
Sex Hormones Promote Opposite Effects on ACE and ACE2 Activity, Hypertrophy and Cardiac Contractility in Spontaneously Hypertensive Rats.
Cardiomegaly
Sub-antihypertensive doses of ramipril normalize sarcoplasmic reticulum calcium ATPase expression and function following cardiac hypertrophy in rats.
Cardiomegaly
Targeted overexpression of the sarcoplasmic reticulum Ca2+-ATPase increases cardiac contractility in transgenic mouse hearts.
Cardiomegaly
TGR5 activation ameliorates hyperglycemia-induced cardiac hypertrophy in H9c2 cells.
Cardiomegaly
The Ca2+ ATPase of cardiac sarcoplasmic reticulum: Physiological role and relevance to diseases.
Cardiomegaly
The effect of treatment with coenzyme Q10 on the mitochondrial function and superoxide radical formation in cardiac muscle hypertrophied by mild aortic stenosis.
Cardiomegaly
The effects of intracellular Ca2+ on cardiac K+ channel expression and activity: novel insights from genetically altered mice.
Cardiomegaly
The plasma membrane calcium ATPase 4 signalling in cardiac fibroblasts mediates cardiomyocyte hypertrophy.
Cardiomegaly
The Role of SUMO-1 in Cardiac Oxidative Stress and Hypertrophy.
Cardiomegaly
The sarco(endo)plasmic reticulum Ca(2+)-ATPase gene is regulated at the transcriptional level during compensated left ventricular hypertrophy in the rat.
Cardiomegaly
Tight interplay between the Ca2+ affinity of the cardiac SERCA2 Ca2+ pump and the SERCA2 expression level.
Cardiomegaly
Total glycosides of Ranunculus japonius prevent hypertrophy in cardiomyocytes via alleviating chronic Ca(2+) overload.
Cardiomegaly
Transcription of the SERCA2 gene is decreased in pressure-overloaded hearts: A study using in vivo direct gene transfer into living myocardium.
Cardiomegaly
Troponin I phosphorylation and myofilament calcium sensitivity during decompensated cardiac hypertrophy.
Cardiomegaly
Unchanged sarcoplasmic reticulum Ca2+-ATPase activity, reduced Ca2+ sensitivity, and negative force-frequency relationship in transgenic rats overexpressing the mouse renin gene.
Cardiomegaly
[Biochemistry of myocardium taken at autopsy. Preliminary report]
Cardiomegaly
[Depression of contractile function and decrease of the effectiveness of oxygen utilization during compensatory heart hypertrophy]
Cardiomegaly
[Effect of astragalus on calcium accumulation and SERCA2a gene expression in myocardial tissues in rats with pressure overload-induced left ventricular hypertrophy]
Cardiomyopathies
A study in Polish patients with cardiomyopathy emphasizes pathogenicity of phospholamban (PLN) mutations at amino acid position 9 and low penetrance of heterozygous null PLN mutations.
Cardiomyopathies
Adenosinetriphosphatase activity of cellular organelles in experimental potassium depletion cardiomyopathy.
Cardiomyopathies
Altered calcium regulation in the cardiac plasma membrane in experimental renal hypertension.
Cardiomyopathies
Cardiac sarcoplasmic reticulum calcium ATPase, an autoimmune antigen in experimental cardiomyopathy.
Cardiomyopathies
Circulating cytokine levels in mice with heart failure are etiology dependent.
Cardiomyopathies
Comparison of the antiremodeling effects of losartan and mirabegron in a rat model of uremic cardiomyopathy.
Cardiomyopathies
Depressed PKA activity contributes to impaired SERCA function and is linked to the pathogenesis of glucose-induced cardiomyopathy.
Cardiomyopathies
Effects of sarcoplasmic reticulum Ca2+-ATPase overexpression in postinfarction rat myocytes.
Cardiomyopathies
Exacerbation of dystrophic cardiomyopathy by phospholamban deficiency-mediated chronically increased cardiac Ca2+ cycling in vivo.
Cardiomyopathies
Gene remodeling in type 2 diabetic cardiomyopathy and its phenotypic rescue with SERCA2a.
Cardiomyopathies
Impact of oxidative posttranslational modifications of SERCA2 on heart failure exacerbation in young patients with non-ischemic cardiomyopathy: A pilot study.
Cardiomyopathies
Impaired Ca2+-ATPase oligomerization and increased phospholamban expression in dilated cardiomyopathy.
Cardiomyopathies
In vitro selection and characterization of DNA aptamers specific for phospholamban.
Cardiomyopathies
Intramyocardial injection of SERCA2a-expressing lentivirus improves myocardial function in doxorubicin-induced heart failure.
Cardiomyopathies
Mechanism of doxorubicin-induced inhibition of sarcoplasmic reticulum Ca(2+)-ATPase gene transcription.
Cardiomyopathies
Messenger RNA expression and immunological quantification of phospholamban and SR-Ca(2+)-ATPase in failing and nonfailing human hearts.
Cardiomyopathies
More severe cellular phenotype in human idiopathic dilated cardiomyopathy compared to ischemic heart disease.
Cardiomyopathies
Overexpression of the sarcoplasmic reticulum Ca(2+)-ATPase improves myocardial contractility in diabetic cardiomyopathy.
Cardiomyopathies
Oxidative posttranslational modifications mediate decreased SERCA activity and myocyte dysfunction in Galphaq-overexpressing mice.
Cardiomyopathies
Phospholamban cardiomyopathy: a Canadian perspective on a unique population.
Cardiomyopathies
Phospholamban overexpression in mice causes a centronuclear myopathy-like phenotype.
Cardiomyopathies
Rheostatic Regulation of the SERCA/Phospholamban Membrane Protein Complex Using Non-Coding RNA and Single-Stranded DNA oligonucleotides.
Cardiomyopathies
Sarcolipin haploinsufficiency prevents dystrophic cardiomyopathy in mdx mice.
Cardiomyopathies
SERCA2a activity correlates with the force-frequency relationship in human myocardium.
Cardiomyopathies
Study on the effect of doxorubicin on expressions of genes encoding myocardial sarcoplasmic reticulum Ca2+ transport proteins and the effect of taurine on myocardial protection in rabbits.
Cardiomyopathies
The role of phospholamban and GSK3 in regulating rodent cardiac SERCA function.
Cardiomyopathies
The synthetic antimicrobial peptide 19-2.5 attenuates septic cardiomyopathy and prevents down-regulation of SERCA2 in polymicrobial sepsis.
Cardiomyopathies
[Functional genomics of pressure-loaded cardiomyocytes: etomoxir in heart failure?]
Cardiomyopathy, Dilated
A mutation in the human phospholamban gene, deleting arginine 14, results in lethal, hereditary cardiomyopathy.
Cardiomyopathy, Dilated
Ca(2+)-transporting ATPase, phospholamban, and calsequestrin levels in nonfailing and failing human myocardium.
Cardiomyopathy, Dilated
cAMP-dependent protein kinase A-stimulated sarcoplasmic reticulum function in heart failure.
Cardiomyopathy, Dilated
Cellular and molecular remodeling in a heart failure model treated with the beta-blocker carteolol.
Cardiomyopathy, Dilated
Compensatory asymmetry in down-regulation and inhibition of the myocardial Ca2+ cycle in congestive heart failure produced in dogs by idiopathic dilated cardiomyopathy and rapid ventricular pacing.
Cardiomyopathy, Dilated
Impaired Ca2+-ATPase oligomerization and increased phospholamban expression in dilated cardiomyopathy.
Cardiomyopathy, Dilated
Impaired Ca2+-sequestration in dilated cardiomyopathy (review).
Cardiomyopathy, Dilated
Messenger RNA expression and immunological quantification of phospholamban and SR-Ca(2+)-ATPase in failing and nonfailing human hearts.
Cardiomyopathy, Dilated
Myocardial Ca-sequestration failure and compensatory increase in Ca-ATPase with congestive cardiomyopathy: kinetic characterization by a homogenate microassay using real-time ratiometric indo-1 spectrofluorometry.
Cardiomyopathy, Dilated
Reconstitution of the cytoplasmic interaction between phospholamban and Ca(2+)-ATPase of cardiac sarcoplasmic reticulum.
Cardiomyopathy, Dilated
Reduced Ca(2+)-sensitivity of SERCA 2a in failing human myocardium due to reduced serin-16 phospholamban phosphorylation.
Cardiomyopathy, Dilated
Single SERCA2a Therapy Ameliorated Dilated Cardiomyopathy for 18 Months in a Mouse Model of Duchenne Muscular Dystrophy.
Cardiomyopathy, Dilated
Structure-function relation of phospholamban: modulation of channel activity as a potential regulator of SERCA activity.
Cardiomyopathy, Dilated
Unchanged protein expression of sarcoplasmic reticulum Ca2+-ATPase, phospholamban, and calsequestrin in terminally failing human myocardium.
Cardiomyopathy, Dilated
Unchanged protein levels of SERCA II and phospholamban but reduced Ca2+ uptake and Ca(2+)-ATPase activity of cardiac sarcoplasmic reticulum from dilated cardiomyopathy patients compared with patients with nonfailing hearts.
Cardiomyopathy, Hypertrophic
Exploring miRNA-mRNA regulatory network in cardiac pathology in Na+/H+ exchanger isoform 1 transgenic mice.
Cardiomyopathy, Hypertrophic
Reduced myocardial sarcoplasmic reticulum Ca(2+)-ATPase mRNA expression and biphasic force-frequency relations in patients with hypertrophic cardiomyopathy.
Cardiomyopathy, Hypertrophic
Sarcoplasmic reticulum calcium defect in Ras-induced hypertrophic cardiomyopathy heart.
Cardiomyopathy, Hypertrophic, Familial
Long-term rescue of a familial hypertrophic cardiomyopathy caused by a mutation in the thin filament protein, tropomyosin, via modulation of a calcium cycling protein.
Cardiomyopathy, Hypertrophic, Familial
Neonatal gene transfer of Serca2a delays onset of hypertrophic remodeling and improves function in familial hypertrophic cardiomyopathy.
Cardiotoxicity
Anthracycline cardiotoxicity in transgenic mice overexpressing SR Ca2+-ATPase.
Cardiotoxicity
Content decline of SERCA inhibitors saikosaponin a and d attenuates cardiotoxicity and hepatotoxicity of vinegar-baked Radix bupleuri.
Cardiotoxicity
E3 Ubiquitin ligase NEDD4 family?regulatory network in cardiovascular disease.
Cardiotoxicity
Erratum: Sarcoendoplasmic Reticulum Ca2+ ATPase. A Critical Target In Chlorine Inhalation-induced Cardiotoxicity.
Cardiotoxicity
In vitro model of ischemic heart failure using human induced pluripotent stem cell-derived cardiomyocytes.
Cardiotoxicity
Melatonin protects against ischemic heart failure in rats.
Cardiotoxicity
The Tumor-Suppressive Human Circular RNA CircITCH Sponges miR-330-5p to Ameliorate Doxorubicin-Induced Cardiotoxicity Through Upregulating SIRT6, Survivin, and SERCA2a.
Cardiovascular Diseases
A Therapeutic Role for the F1FO-ATP Synthase.
Cardiovascular Diseases
Benefit of SERCA2a gene transfer to vascular endothelial and smooth muscle cells: a new aspect in therapy of cardiovascular diseases.
Cardiovascular Diseases
Detection of sequence-specific tyrosine nitration of manganese SOD and SERCA in cardiovascular disease and aging.
Cardiovascular Diseases
Modulation of vascular sarco/endoplasmic reticulum calcium ATPase in cardiovascular pathophysiology.
Cardiovascular Diseases
Role of sarco/endoplasmic reticulum calcium content and calcium ATPase activity in the control of cell growth and proliferation.
Cardiovascular Diseases
Targeting the redox regulation of SERCA in vascular physiology and disease.
Cardiovascular Diseases
Targeting the sarcolemmal calcium pump: a potential novel strategy for the treatment of cardiovascular disease.
Cardiovascular Diseases
The cardiac sarcoplasmic/endoplasmic reticulum calcium ATPase: a potent target for cardiovascular diseases.
Cardiovascular Diseases
Transgenic rat hearts overexpressing SERCA2a show improved contractility under baseline conditions and pressure overload.
Carotid Artery Injuries
Upregulation of Nox4 by TGF{beta}1 oxidizes SERCA and inhibits NO in arterial smooth muscle of the prediabetic Zucker rat.
Cataract
Changes in plasma membrane Ca2+ -ATPase expression and ATP content in lenses of hereditary cataract UPL rats.
Cataract
Comparison of the mechanisms of cataract development involving differences in Ca2+ regulation in lenses among three hereditary cataract model rats.
Cataract
Effect of disulfiram eye drops on lipid peroxide formation via excessive nitric oxide in lenses of hereditary cataract ICR/f rats.
Cataract
Effect of oxidation on Ca2+ -ATPase activity and membrane lipids in lens epithelial microsomes.
Cataract
Plasma membrane Ca-ATPase isoform expression in human cataractous lenses compared to age-matched clear lenses.
Cataract
The relationship between properties of antipsychotic drugs and cataract formation.
Cataract
[Ca(2+)-ATPase activity in the hypocalcemic cataract]
Cerebellar Ataxia
A Novel Mutation in Isoform 3 of the Plasma Membrane Ca2+ Pump Impairs Cellular Ca2+ Homeostasis in a Patient with Cerebellar Ataxia and Laminin Subunit 1? Mutations.
Cerebellar Ataxia
A novel PMCA3 mutation in an ataxic patient with hypomorphic phosphomannomutase 2 (PMM2) heterozygote mutations: Biochemical characterization of the pump defect.
Cerebellar Ataxia
A V1143F mutation in the neuronal-enriched isoform 2 of the PMCA pump is linked with ataxia.
Cerebellar Ataxia
Enhanced Synaptic Inhibition in the Cerebellar Cortex of the Ataxic PMCA2(-/-) Knockout Mouse.
Cerebellar Ataxia
Mutation of plasma membrane Ca2+ ATPase isoform 3 in a family with X-linked congenital cerebellar ataxia impairs Ca2+ homeostasis.
Cerebellar Ataxia
Survival strategies for mouse cerebellar Purkinje neurons lacking PMCA2.
Cerebellar Ataxia
The ataxia related G1107D mutation of the plasma membrane Ca(2+) ATPase isoform 3 affects its interplay with calmodulin and the autoinhibition process.
Cerebral Hemorrhage
Modulation of crucial adenosinetriphosphatase activities due to U-74389G administration in a porcine model of intracerebral hemorrhage.
Cerebral Infarction
Secretory pathway Ca2+-ATPase isoform 1 knockdown promotes Golgi apparatus stress injury in a mouse model of focal cerebral ischemia-reperfusion: In vivo and in vitro study.
Chagas Disease
Upregulation of cardiac cell plasma membrane calcium pump in a canine model of Chagas disease.
Cholera
Ca2+/calmodulin-dependent protein kinase II is an essential mediator in the coordinated regulation of electrocyte Ca2+-ATPase by calmodulin and protein kinase A.
Cholera
Glucagon-(19-29) exerts a biphasic action on the liver plasma membrane Ca2+ pump which is mediated by G proteins.
Cholera
Rapid membrane responses to dihydrotestosterone are sex dependent in growth plate chondrocytes.
Cholera
Role of G protein beta gamma subunits in the regulation of the plasma membrane Ca2+ pump.
Cholera
The effect of cholera toxin on human red cell Ca-ATPase.
Cholestasis
Induction of cholestasis in the perfused rat liver by 2-aminoethyl diphenylborate, an inhibitor of the hepatocyte plasma membrane Ca2+ channels.
Choriocarcinoma
81 MEMBRANE AND CYTOSOLIC CALCIUM PROTEINS, TRPV6, PMCA1, NCKX3, NCX1 AND CaBP-28k, APPEAR TO BE DISTINCTLY REGULATED IN HUMAN CHORIOCARCINOMA AND PLACENTAL CELLS.
Choroid Plexus Neoplasms
Loss of endoplasmic reticulum calcium pump expression in choroid plexus tumours.
Colitis
CaM kinase II in colonic smooth muscle contributes to dysmotility in murine DSS-colitis.
Colonic Neoplasms
Artemisinin induces doxorubicin resistance in human colon cancer cells via calcium-dependent activation of HIF-1alpha and P-glycoprotein overexpression.
Colonic Neoplasms
Expression of endomembrane calcium pumps in colon and gastric cancer cells. Induction of SERCA3 expression during differentiation.
Colonic Neoplasms
Induction of cell differentiation activates transcription of the Sarco/Endoplasmic Reticulum calcium-ATPase 3 gene (ATP2A3) in gastric and colon cancer cells.
Colonic Neoplasms
Plasma membrane Ca2+-ATPase expression during colon cancer cell line differentiation.
Colonic Neoplasms
Plasma membrane calcium ATPase 4 and the remodeling of calcium homeostasis in human colon cancer cells.
Colonic Neoplasms
Plasma membrane calcium ATPase expression in human colon multistep carcinogenesis.
Colonic Neoplasms
Selective upregulation of the expression of plasma membrane calcium ATPase isoforms upon differentiation and 1,25(OH)2D3-vitamin treatment of colon cancer cells.
Colonic Neoplasms
The Ca2+/Mn2+-transporting SPCA2 pump is regulated by oxygen and cell density in colon cancer cells.
Colonic Neoplasms
The loss of sarco/endoplasmic reticulum calcium transport ATPase 3 expression is an early event during the multistep process of colon carcinogenesis.
Colorectal Neoplasms
Aberrant SERCA3 expression during the colorectal adenoma-adenocarcinoma sequence.
Colorectal Neoplasms
Dihydroartemisinin-Induced Apoptosis is Associated with Inhibition of Sarco/Endoplasmic Reticulum Calcium ATPase Activity in Colorectal Cancer.
Colorectal Neoplasms
Novel role of Sarco/endoplasmic reticulum calcium ATPase 2 in development of colorectal cancer and its regulation by F36, a curcumin analog.
Colorectal Neoplasms
Sarco/endoplasmic reticulum calcium-ATPase 2 expression as a tumor marker in colorectal cancer.
Colorectal Neoplasms
Small molecule RL71 targets SERCA2 at a novel site in the treatment of human colorectal cancer.
Colorectal Neoplasms
[The activity of adenosinetriphosphatase of erythrocytes in peripheral blood of patients with colorectal cancer]
Coma
A new genetic model of activity-induced Ras signaling dependent pre-synaptic plasticity in Drosophila.
Contracture
Ca2+ handling by rat myocardium exposed to ATP solutions of different [Ca2+] and Ca2+ buffering capacity.
Contracture
Dependence of cyclopiazonic-acid-induced muscle contractures on extracellular Ca2+.
Contracture
Effect of halothane on the Ca2+-transport system of surface membranes isolated from normal and malignant hyperthermia pig skeletal muscle.
Contracture
Evidence for Mg2, ATP-dependent accumulation of Ca2+ by the intracellular non-mitochondrial calcium store in uterine smooth muscle cells.
Contracture
Inhibition of sarcoplasmic Ca2+-ATPase increases caffeine- and halothane-induced contractures in muscle bundles of malignant hyperthermia susceptible and healthy individuals.
Contracture
Mechanism of contracture on cooling of caffeine-treated frog skeletal muscle fibres.
Contracture
Mitochondrial Bioenergetics During Ischemia and Reperfusion.
Contracture
Na(+)-Ca2+ exchange induces low Na+ contracture in frog skeletal muscle fibers after partial inhibition of sarcoplasmic reticulum Ca(2+)-ATPase.
Contracture
Role of calcium in acute hyperthermic myocardial injury.
Contracture
SERCA2A overexpression decreases the incidence of aftercontractions in adult rabbit ventricular myocytes.
Contracture
The effects of quinine on the calcium and magnesium content of the sarcoplasmic reticulum and the temperature-dependence of quinine contractures.
Contracture
[Myocardial mechanical injury in acute ischemia: a pathophysiologic and histopathologic review]
Contracture
[The calcium pump in the sarcolemma controls smooth muscle relaxation]
Contracture
[Uterotonic action of sigetin and its effect on the Mg2+, ATP-dependent transport and stationary metabolism of Ca2+ through the myometrial sarcolemma]
Coronary Disease
[Study of the calmodulin-dependent regulation of calcium adenosine triphosphatase of erythrocyte membranes in patients with ischemic heart disease]
Coronary Occlusion
Ischaemia-induced changes in canine cardiac sarcoplasmic reticulum.
Craniocerebral Trauma
[Disordered phosphorus metabolism and its correction in the acute period of severe craniocerebral trauma]
Cryptorchidism
Sarco(endo)plasmic reticulum and plasmalemmal Ca(2+)-ATPase activities in cremaster muscles and sacs differ according to the associated inguinal pathology.
Cystic Fibrosis
A study of erythrocyte fatty acids, adenosinetriphosphatase and acetylcholinesterase in cystic fibrosis.
Cystic Fibrosis
Activator-associated Ca2+-ATPase in erythrocyte membranes from cystic fibrosis patients.
Cystic Fibrosis
Bcl-2 suppresses sarcoplasmic/endoplasmic reticulum Ca2+-ATPase expression in cystic fibrosis airways: role in oxidant-mediated cell death.
Cystic Fibrosis
Calcium and sodium transport processes in patients with cystic fibrosis 2. Mg2+- dependent, Ca2+ ATPase activity in fibroblast membrane preparations from cystic fibrosis patients and controls.
Cystic Fibrosis
Calcium and sodium transport processes in patients with cystic fibrosis. I. A specific decrease in Mg2+-dependent, Ca2+-adenosine triphosphatase activity in erythrocyte membranes from cystic fibrosis patients.
Cystic Fibrosis
Calcium-ATPase activity in cystic fibrosis erythrocyte membranes: decreased activity in patients with pancreatic insufficiency.
Cystic Fibrosis
Characterization of the adenosinetriphosphatase and transport activities of purified cystic fibrosis transmembrane conductance regulator.
Cystic Fibrosis
Curcumin modulation of Na,K-ATPase: phosphoenzyme accumulation, decreased K+ occlusion, and inhibition of hydrolytic activity.
Cystic Fibrosis
Erythrocyte cytosolic free Ca2+ and plasma membrane Ca2+-ATPase activity in cystic fibrosis.
Cystic Fibrosis
Identification of the cofilin-binding sites in the large cytoplasmic domain of Na,K-ATPase.
Cystic Fibrosis
Isolation and characterization of erythrocyte membrane Ca2+-ATPase in cystic fibrosis.
Cystic Fibrosis
Phosphoinositide content of erythrocyte membranes in cystic fibrosis.
Cystic Fibrosis
Red cell membrane Ca-ATPase in cystic fibrosis: increased activation by Na.
Cystic Fibrosis
SERCA Pump Inhibitors Do Not Correct Biosynthetic Arrest of {Delta}F508 CFTR in Cystic Fibrosis.
Cystinosis
Structure of the human sarco/endoplasmic reticulum Ca2+-ATPase 3 gene. Promoter analysis and alternative splicing of the SERCA3 pre-mRNA.
Cysts
Entamoeba invadens: Identification of a SERCA protein and effect of SERCA inhibitors on encystation.
Cysts
Proposed function of the accumulation of plasma membrane-type Ca2+-ATPase mRNA in resting cysts of the ciliate Sterkiella histriomuscorum.
Darier Disease
A case of segmental Darier disease treated with doxycycline monotherapy.
Darier Disease
Activity of the hSPCA1 Golgi Ca2+ pump is essential for Ca2+-mediated Ca2+ response and cell viability in Darier disease.
Darier Disease
Autosomal-dominant calcium ATPase disorders.
Darier Disease
Brain-specific heterozygous loss-of-function of ATP2A2, endoplasmic reticulum Ca2+ pump responsible for Darier's disease, causes behavioral abnormalities and a hyper-dopaminergic state.
Darier Disease
Comprehensive analysis of expression and function of 51 sarco(endo)plasmic reticulum Ca2+-ATPase mutants associated with Darier disease.
Darier Disease
Congenital acantholytic dyskeratotic epidermal naevus following Blaschko's lines versus segmental Darier's disease.
Darier Disease
Consequences of depleted SERCA2-gated calcium stores in the skin.
Darier Disease
Darier disease is associated with heart failure: a cross-sectional case-control and population based study.
Darier Disease
Darier's disease associated with bipolar affective disorder: a case report.
Darier Disease
Darier's disease following radiotherapy for carcinoma of cervix.
Darier Disease
Darier's disease: from dyskeratosis to endoplasmic reticulum calcium ATPase deficiency.
Darier Disease
Deletions of any single residues in Glu40-Ser48 loop connecting a domain and the first transmembrane helix of sarcoplasmic reticulum Ca(2+)-ATPase result in almost complete inhibition of conformational transition and hydrolysis of phosphoenzyme intermediate.
Darier Disease
Dissection of the functional differences between sarco(endo)plasmic reticulum Ca2+-ATPase (SERCA) 1 and 2 isoforms and characterization of Darier disease (SERCA2) mutants by steady-state and transient kinetic analyses.
Darier Disease
Endoplasmic reticulum calcium, stress, and cell-to-cell adhesion.
Darier Disease
Evidence for familial cosegregation of major affective disorder and genetic markers flanking the gene for Darier's disease.
Darier Disease
Exacerbation of darier disease by lithium carbonate.
Darier Disease
Exclusion of the Darier's disease gene, ATP2A2, as a common susceptibility gene for bipolar disorder.
Darier Disease
Expression of sarco/endo-plasmic reticulum Ca2+-ATPase type 2 isoforms (SERCA2) in normal human skin and mucosa, and Darier's disease skin.
Darier Disease
Expression of the sarco/endoplasmic reticulum calcium ATPase type 2 and 3 isoforms in normal skin and Darier's disease.
Darier Disease
Genotype-phenotype correlations in Darier disease: A focus on the neuropsychiatric phenotype.
Darier Disease
Haploinsufficiency of Atp2a2, encoding the sarco(endo)plasmic reticulum Ca2+-ATPase isoform 2 Ca2+ pump, predisposes mice to squamous cell tumors via a novel mode of cancer susceptibility.
Darier Disease
Heterozygous disruption of SERCA2a is not associated with impairment of cardiac performance in humans: implications for SERCA2a as a therapeutic target in heart failure.
Darier Disease
How do keratinizing disorders and blistering disorders overlap?
Darier Disease
Is Darier Disease a Multi-organ Condition?
Darier Disease
Keratinocytes cultured from patients with Hailey-Hailey disease and Darier disease display distinct patterns of calcium regulation.
Darier Disease
Lithium suppresses epidermal SERCA2 and PMR1 levels in the rat.
Darier Disease
Metabolic phenotype in Darier disease: a cross-sectional clinical study.
Darier Disease
Multiple effects of SERCA2b mutations associated with Darier's disease.
Darier Disease
Mutations in ATP2A2, encoding a Ca2+ pump, cause Darier disease.
Darier Disease
Mutations in ATP2C1, encoding a calcium pump, cause Hailey-Hailey disease.
Darier Disease
Mutations in the sarcoplasmic/endoplasmic reticulum Ca2+ ATPase isoform cause Darier's disease.
Darier Disease
Novel allelic mutations in murine Serca2 induce differential development of squamous cell tumors.
Darier Disease
Novel ATP2A2 mutations in a large sample of individuals with Darier disease.
Darier Disease
Physiological functions of plasma membrane and intracellular Ca2+ pumps revealed by analysis of null mutants.
Darier Disease
Plasticity and adaptation of Ca2+ signaling and Ca2+-dependent exocytosis in SERCA2(+/-) mice.
Darier Disease
Platelet and cardiac function in Darier's disease.
Darier Disease
Protein aggregation of SERCA2 mutants associated with Darier disease elicits ER stress and apoptosis in keratinocytes.
Darier Disease
Role of Sp1 in transcription of human ATP2A2 gene in keratinocytes.
Darier Disease
Sarco/endoplasmic reticulum Ca2+-ATPase (SERCA) activity is required for V(D)J recombination.
Darier Disease
Secretory pathway stress responses as possible mechanisms of disease involving Golgi Ca2+ pump dysfunction.
Darier Disease
SERCA pumps and human diseases.
Darier Disease
SERCA2 Dysfunction in Darier Disease Causes Endoplasmic Reticulum Stress and Impaired Cell-to-Cell Adhesion Strength: Rescue by Miglustat.
Darier Disease
SERCA2 Haploinsufficiency in a Mouse Model of Darier Disease Causes a Selective Predisposition to Heart Failure.
Darier Disease
The Focal Nature of Darier's Disease Lesions: Calcium Pumps, Stress, and Mutation?
Darier Disease
Treatment of Darier's disease with oral magnesium: a case report.
Darier Disease
Type 1 Segmental Darier Disease: Case Report and Discussion of the Treatment Options.
Darier Disease
Up-Regulation of Transient Receptor Potential Canonical 1 (TRPC1) following Sarco(endo)plasmic Reticulum Ca2+ ATPase 2 Gene Silencing Promotes Cell Survival: A Potential Role for TRPC1 in Darier's Disease.
Darier Disease
Variable response to low-dose naltrexone in patients with Darier disease: a case series.
Darier Disease
[Detection and analysis of an ATP2A2 mutation in a family with Darier-White disease].
Darier Disease
[Improvement of Darier's disease on treatment with topical 5-fluorouracil]
Deafness
Ca2+ homeostasis defects and hereditary hearing loss.
Deafness
Calcium pumps of plasma membrane and cell interior.
Deafness
Distinct phenotypes among plasma membrane Ca2+-ATPase knockout mice.
Deafness
Hair cells, plasma membrane Ca(2+) ATPase and deafness.
Deafness
Low endolymph calcium concentrations in deafwaddler2J mice suggest that PMCA2 contributes to endolymph calcium maintenance.
Deafness
Maintenance of neuronal size gradient in MNTB requires sound-evoked activity.
Deafness
Mutations in a plasma membrane Ca2+-ATPase gene cause deafness in deafwaddler mice.
Deafness
Mutations in PMCA2 and hereditary deafness: a molecular analysis of the pump defect.
Deafness
Neuroplastin expression is essential for hearing and hair cell PMCA expression.
Deafness
Phenotypes of SERCA and PMCA knockout mice.
Deafness
PMCA2 pump mutations and hereditary deafness.
Deafness
The novel PMCA2 pump mutation Tommy impairs cytosolic calcium clearance in hair cells and links to deafness in mice.
Deafness
The plasma membrane calcium pump in health and disease.
Deafness
The plasma membrane calcium pump in the hearing process: physiology and pathology.
Death, Sudden, Cardiac
Acute heart failure--basic pathomechanism and new drug targets.
Death, Sudden, Cardiac
SERCA2a gene therapy for the prevention of sudden cardiac death: a future theranostic for heart failure?
Decompression Sickness
Mutation of Gly-94 in transmembrane segment M1 of Na+,K+-ATPase interferes with Na+ and K+ binding in E2P conformation.
Dehydration
Concentration-dependent suppressive effect of shrimp head protein hydrolysate on dehydration-induced denaturation of lizardfish myofibrils.
Dehydration
Effect of proteolytic squid protein hydrolysate on the state of water and dehydration-induced denaturation of lizard fish myofibrillar protein.
Dehydration
Up-down biphasic volume response of human red blood cells to PIEZO1 activation during capillary transits.
Demyelinating Diseases
Changes in the distribution of a calcium-dependent ATPase during demyelination and remyelination in the central nervous system.
Dengue
Diverse Viruses Require the Calcium Transporter SPCA1 for Maturation and Spread.
Diabetes Insipidus, Nephrogenic
Rescue of vasopressin V2 receptor mutants by chemical chaperones: specificity and mechanism.
Diabetes Mellitus
Alterations in cardiac sarcolemmal Ca2+ pump activity during diabetes mellitus.
Diabetes Mellitus
Cardiac contracile protein ATPase activity in a diet induced model of noninsulin dependent diabetes mellitus.
Diabetes Mellitus
Cellular Ca2+ ATPase activity in diabetes mellitus.
Diabetes Mellitus
Increased myocardial SERCA expression in early type 2 diabetes mellitus is insulin dependent: In vivo and in vitro data.
Diabetes Mellitus
Inverse correlation between levels of glycated haemoglobin and expression levels of SERCA protein in Mexican patients with type 2 diabetes mellitus.
Diabetes Mellitus
Mechanical and metabolic rescue in a type II diabetes model of cardiomyopathy by targeted gene transfer.
Diabetes Mellitus
Phospholamban Antisense RNA Improves SR Ca2+-ATPase Activity and Left Ventricular Function in STZ-induced Diabetic Rats.
Diabetes Mellitus
Platelet sarcoplasmic endoplasmic reticulum Ca2+-ATPase and mu-calpain activity are altered in type 2 diabetes mellitus and restored by rosiglitazone.
Diabetes Mellitus
Regulation of SERCA pumps expression in diabetes.
Diabetes Mellitus
Transcoronary gene transfer of SERCA2a increases coronary blood flow and decreases cardiomyocyte size in a type 2 diabetic rat model.
Diabetes Mellitus, Type 1
Altered platelet membrane dynamic properties in type 1 diabetes.
Diabetes Mellitus, Type 1
ATP dependent Ca2+ transport across basal membrane of human syncytiotrophoblast in pregnancies complicated by intrauterine growth restriction or diabetes.
Diabetes Mellitus, Type 1
Carbonylation contributes to SERCA2a activity loss and diastolic dysfunction in a rat model of type 1 diabetes.
Diabetes Mellitus, Type 1
Cardiomyocyte dysfunction in models of type 1 and type 2 diabetes.
Diabetes Mellitus, Type 1
Cellular Ca2+ ATPase activity in diabetes mellitus.
Diabetes Mellitus, Type 1
Effects of type 1 diabetes, sprint training and sex on skeletal muscle sarcoplasmic reticulum Ca2+ uptake and Ca2+-ATPase activity.
Diabetes Mellitus, Type 1
Influence of low density lipoprotein from insulin-dependent diabetic patients on platelet functions.
Diabetes Mellitus, Type 1
Regulation of SERCA pumps expression in diabetes.
Diabetes Mellitus, Type 1
Resveratrol, an activator of SIRT1, upregulates sarcoplasmic calcium ATPase and improves cardiac function in diabetic cardiomyopathy.
Diabetes Mellitus, Type 1
Sensory neurons derived from diabetic rats have diminished internal Ca2+ stores linked to impaired re-uptake by the endoplasmic reticulum.
Diabetes Mellitus, Type 1
The Endoplasmic Reticulum and Calcium Homeostasis in Pancreatic Beta Cells.
Diabetes Mellitus, Type 2
Ca++, Mg++-ATPase activity in insulin-dependent and non-insulin dependent diabetic Nigerians.
Diabetes Mellitus, Type 2
Ca2+-Mg2+-ATPase activity in kidney basolateral membrane in non-insulin-dependent diabetic rats. Effect of insulin.
Diabetes Mellitus, Type 2
Cardiac contracile protein ATPase activity in a diet induced model of noninsulin dependent diabetes mellitus.
Diabetes Mellitus, Type 2
Cellular Ca2+ ATPase activity in diabetes mellitus.
Diabetes Mellitus, Type 2
Endogenously generated reactive oxygen species reduce PMCA activity in platelets from patients with non-insulin-dependent diabetes mellitus.
Diabetes Mellitus, Type 2
Gene remodeling in type 2 diabetic cardiomyopathy and its phenotypic rescue with SERCA2a.
Diabetes Mellitus, Type 2
Increased myocardial SERCA expression in early type 2 diabetes mellitus is insulin dependent: In vivo and in vitro data.
Diabetes Mellitus, Type 2
Inverse correlation between levels of glycated haemoglobin and expression levels of SERCA protein in Mexican patients with type 2 diabetes mellitus.
Diabetes Mellitus, Type 2
Isoforms of endoplasmic reticulum Ca(2+)-ATPase are differentially expressed in normal and diabetic islets of Langerhans.
Diabetes Mellitus, Type 2
Platelet sarcoplasmic endoplasmic reticulum Ca2+-ATPase and mu-calpain activity are altered in type 2 diabetes mellitus and restored by rosiglitazone.
Diabetes Mellitus, Type 2
PPAR-? activation restores pancreatic islet SERCA2 levels and prevents ?-cell dysfunction under conditions of hyperglycemic and cytokine stress.
Diabetes Mellitus, Type 2
Reduced plasma membrane Ca2+-ATPase function in platelets from patients with non-insulin-dependent diabetes mellitus.
Diabetes Mellitus, Type 2
Role of cellular calcium metabolism in abnormal glucose metabolism and diabetic hypertension.
Diabetes Mellitus, Type 2
Sarco(endo)plasmic reticulum Ca2+-ATPase 2b is a major regulator of endoplasmic reticulum stress and glucose homeostasis in obesity.
Diabetes Mellitus, Type 2
Small Molecular Allosteric Activator of the Sarco/Endoplasmic Reticulum Ca2+-ATPase (SERCA) Attenuates Diabetes and Metabolic Disorders.
Diabetes Mellitus, Type 2
The effect of glucose and calcium on Ca2+-adenosine triphosphatase in pancreatic islets isolated from a normal and a non-insulin-dependent diabetes mellitus rat model.
Diabetes Mellitus, Type 2
The Endoplasmic Reticulum and Calcium Homeostasis in Pancreatic Beta Cells.
Diabetes Mellitus, Type 2
The pathobiochemical role of the dystrophin-dystroglycan complex and the Ca2+-handling apparatus in diabetes-related muscle weakness (Review).
Diabetes Mellitus, Type 2
Transcoronary gene transfer of SERCA2a increases coronary blood flow and decreases cardiomyocyte size in a type 2 diabetic rat model.
Diabetic Cardiomyopathies
A novel endothelin receptor antagonist CPU0213 improves diabetic cardiac insufficiency attributed to up-regulation of the expression of FKBP12.6, SERCA2a, and PLB in rats.
Diabetic Cardiomyopathies
Cardiomyocyte dysfunction in models of type 1 and type 2 diabetes.
Diabetic Cardiomyopathies
Conditional increase in SERCA2a protein is able to reverse contractile dysfunction and abnormal calcium flux in established diabetic cardiomyopathy.
Diabetic Cardiomyopathies
Enhanced L-type calcium currents in cardiomyocytes from transgenic rats overexpressing SERCA2a.
Diabetic Cardiomyopathies
Gene remodeling in type 2 diabetic cardiomyopathy and its phenotypic rescue with SERCA2a.
Diabetic Cardiomyopathies
Impaired cardiac function and IGF-I response in myocytes from calmodulin-diabetic mice: role of Akt and RhoA.
Diabetic Cardiomyopathies
Left ventricular diastolic dysfunction in type 2 diabetes mellitus model rats.
Diabetic Cardiomyopathies
Leukocytic toll-like receptor 2 knockout protects against diabetes-induced cardiac dysfunction.
Diabetic Cardiomyopathies
Overexpression of the sarcoplasmic reticulum Ca(2+)-ATPase improves myocardial contractility in diabetic cardiomyopathy.
Diabetic Cardiomyopathies
Regulation of SERCA pumps expression in diabetes.
Diabetic Cardiomyopathies
SERCA2a stimulation by istaroxime improves intracellular Ca2+ handling and diastolic dysfunction in a model of diabetic cardiomyopathy.
Diabetic Cardiomyopathies
Sildenafil and FDP-Sr attenuate diabetic cardiomyopathy by suppressing abnormal expression of myocardial CASQ2, FKBP12.6, and SERCA2a in rats.
Diabetic Cardiomyopathies
Total triterpene acids, active ingredients from Fructus Corni, attenuate diabetic cardiomyopathy by normalizing ET pathway and expression of FKBP12.6 and SERCA2a in streptozotocin-rats.
Diabetic Cardiomyopathies
Transgenic overexpression of the sarcoplasmic reticulum Ca2+ATPase improves reticular Ca2+ handling in normal and diabetic rat hearts.
Diabetic Retinopathy
Inactivation of cysteine 674 in the sarcoplasmic/endoplasmic reticulum calcium ATPase 2 causes retinopathy in the mouse.
dna topoisomerase (atp-hydrolysing) deficiency
Plasma membrane calcium ATPase deficiency causes neuronal pathology in the spinal cord: a potential mechanism for neurodegeneration in multiple sclerosis and spinal cord injury.
Down Syndrome
Cardiac expression of sarcoplasmic reticulum calcium ATPase in fetuses with trisomy 21 and trisomy 18 presenting with nuchal translucency.
Duodenal Ulcer
Effect of daily oral omeprazole on 24 hour intragastric acidity.
Dyskinesias
A new target for Parkinson's disease: Small molecule SERCA activator CDN1163 ameliorates dyskinesia in 6-OHDA-lesioned rats.
Dyslipidemias
Exercise training prevents Ca2+ dysregulation in coronary smooth muscle from diabetic dyslipidemic yucatan swine.
Dyslipidemias
Green tea impedes dyslipidemia, lipid peroxidation, protein glycation and ameliorates Ca2+ -ATPase and Na+/K+ -ATPase activity in the heart of streptozotocin-diabetic rats.
Dyslipidemias
Increased calcium buffering in coronary smooth muscle cells from diabetic dyslipidemic pigs.
Dyslipidemias
[Metabolic syndrome. Part III: Its prevention and therapeutic management.]
Eclampsia
Association of ATP2B1 gene polymorphism with incidence of eclampsia.
Encephalomyelitis
Pathological pain processing in mouse models of multiple sclerosis and spinal cord injury: contribution of plasma membrane calcium ATPase 2 (PMCA2).
Encephalomyelitis
Plasma membrane calcium ATPase deficiency causes neuronal pathology in the spinal cord: a potential mechanism for neurodegeneration in multiple sclerosis and spinal cord injury.
Encephalomyelitis
Reduced expression of plasma membrane calcium ATPase 2 and collapsin response mediator protein 1 promotes death of spinal cord neurons.
Encephalomyelitis
Role of plasma membrane calcium ATPase 2 in spinal cord pathology.
Encephalomyelitis
Temporal pattern of plasma membrane calcium ATPase 2 expression in the spinal cord correlates with the course of clinical symptoms in two rodent models of autoimmune encephalomyelitis.
Encephalomyelitis, Autoimmune, Experimental
Pathological pain processing in mouse models of multiple sclerosis and spinal cord injury: contribution of plasma membrane calcium ATPase 2 (PMCA2).
Encephalomyelitis, Autoimmune, Experimental
Plasma membrane calcium ATPase deficiency causes neuronal pathology in the spinal cord: a potential mechanism for neurodegeneration in multiple sclerosis and spinal cord injury.
Encephalomyelitis, Autoimmune, Experimental
Reduced expression of plasma membrane calcium ATPase 2 and collapsin response mediator protein 1 promotes death of spinal cord neurons.
Encephalomyelitis, Autoimmune, Experimental
Role of plasma membrane calcium ATPase 2 in spinal cord pathology.
Endolymphatic Hydrops
Changes in Ca2+-ATPase in a guinea pig endolymphatic hydrops model.
Endolymphatic Hydrops
Na+,K+-ATPase and Ca2+-ATPase activities in the cochlear lateral wall following surgical induction of hydrops.
Endotoxemia
Resveratrol protects against lipopolysaccharide-induced cardiac dysfunction by enhancing SERCA2a activity through promoting the phospholamban oligomerization.
Endotoxemia
Thaliporphine ameliorates cardiac depression in endotoxemic rats through attenuating TLR4 signaling in the downstream of TAK-1 phosphorylation and NF-?B signaling.
Essential Hypertension
Ca2+ ATPase activity in essential and renal hypertension.
Essential Hypertension
Calmodulin distribution and Ca2+ transport in the erythrocytes of patients with essential hypertension.
Essential Hypertension
Combined SSCP and heteroduplex analysis of the human plasma membrane Ca(2+)-ATPase isoform 1 in patients with essential hypertension.
Essential Hypertension
Comparison of calcium, magnesium-ATPase activity and membrane fluidity in patients with essential hypertension and in normotensive controls.
Essential Hypertension
Erythrocyte membrane Ca2+-pumping ATPase of hypertensive humans: reduced stimulation by calmodulin.
Essential Hypertension
Investigation of the Met-267 Arg exchange in isoform 1 of the human plasma membrane calcium pump in patients with essential hypertension by the amplification-created restriction site technique.
Essential Hypertension
Platelet membrane calmodulin-stimulated calcium-adenosine triphosphatase. Altered activity in essential hypertension.
Essential Hypertension
Red blood cells Ca2+ pump is not altered in essential hypertension of humans and Kyoto rats.
Essential Hypertension
[Hemodynamics and cell membrane effects of angiotensin II receptor antagonists in treatment of hypertension]
Essential Hypertension
[Role of the M235T (c.704c>T) polymorphism of angiotensynogen gene as well as A724A (c.2171G>A) polymorphism of SERCA2a gene in ethiopathogenesis of left ventricular hypertrophy in essential hypertension]
Euthyroid Sick Syndromes
Thyroxine increases Serca2 and Ryr2 gene expression in heart failure rats with euthyroid sick syndrome.
Exocrine Pancreatic Insufficiency
Calcium-ATPase activity in cystic fibrosis erythrocyte membranes: decreased activity in patients with pancreatic insufficiency.
Fatty Liver
MicroRNA-30b Regulates Insulin Sensitivity by Targeting SERCA2b in Non-alcoholic Fatty Liver Disease.
Favism
Impairment of the calcium pump of human erythrocytes by divicine.
Favism
Mechanisms of perturbation of erythrocyte calcium homeostasis in favism.
Fetal Growth Retardation
Changes in calcium channel proteins according to magnesium sulfate administration in placentas from pregnancies with pre-eclampsia or fetal growth restriction.
Fetal Growth Retardation
IFPA 2005 Award in Placentology Lecture. Human placental transport in altered fetal growth: does the placenta function as a nutrient sensor? -- a review.
Gangliosidoses
An exposed carboxyl group on sialic acid is essential for gangliosides to inhibit calcium uptake via the sarco/endoplasmic reticulum Ca2+-ATPase: relevance to gangliosidoses.
Gaucher Disease
Endoplasmic reticulum Ca2+ increases enhance mutant glucocerebrosidase proteostasis.
Genetic Diseases, Inborn
Characterization of Hailey-Hailey Disease-mutants in presence and absence of wild type SPCA1 using Saccharomyces cerevisiae as model organism.
Genetic Diseases, Inborn
[Antidesmoglein antibodies in a patient with Hailey-Hailey disease].
Glioblastoma
Changes in intracellular Ca2+ and pH in response to thapsigargin in human glioblastoma cells and normal astrocytes.
Glioma
5-HT2A receptor activation leads to increased BDNF mRNA expression in C6 glioma cells.
Glioma
ACYP2 contributes to malignant progression of glioma through promoting Ca2+ efflux and subsequently activating c-Myc and STAT3 signals.
Glioma
Bradykinin and muscarine induce Ca(2+)-dependent oscillations of membrane potential in rat glioma cells indicating a rhythmic Ca2+ release from internal stores: thapsigargin and 2,5-di(tert-butyl)-1, 4-benzohydroquinone deplete InsP3-sensitive Ca2+ stores in glioma and in neuroblastoma-glioma hybrid cells.
Glioma
Differentiation of answer of glioma C6 cells to SERCA pump inhibitors by actin disorganization.
Glioma
Sulindac sulfide inhibits sarcoendoplasmic reticulum Ca2+ ATPase, induces endoplasmic reticulum stress response, and exerts toxicity in glioma cells: relevant similarities to and important differences from celecoxib.
Glomerulonephritis
[The functional properties of the erythrocyte membranes in patients with chronic glomerulonephritis]
Glucose Intolerance
Phospholamban Deficiency Does Not Alter Skeletal Muscle SERCA Pumping Efficiency or Predispose Mice to Diet-Induced Obesity.
Glycogen Storage Disease Type V
A Transcriptomic Approach to Search for Novel Phenotypic Regulators in McArdle Disease.
Glycogen Storage Disease Type VII
Increased erythrocyte content of Ca2+ in patients with Tarui's disease.
Goiter
[Cytochemical definition of oxidation-reduction enzyme activity peripheral blood lymphocytes in patients with thyrotoxic goiter]
Gray Platelet Syndrome
Abnormal cAMP-induced phosphorylation of rap 1 protein in grey platelet syndrome platelets.
Hearing Disorders
Characterization of the deafwaddler mutant of the rat plasma membrane calcium-ATPase 2.
Hearing Loss
A de novo deafwaddler mutation of Pmca2 arising in ES cells and hitchhiking with a targeted modification of the Pparg gene.
Hearing Loss
A functional study of plasma-membrane calcium-pump isoform 2 mutants causing digenic deafness.
Hearing Loss
A V1143F mutation in the neuronal-enriched isoform 2 of the PMCA pump is linked with ataxia.
Hearing Loss
Ca2+ homeostasis defects and hereditary hearing loss.
Hearing Loss
Haplo-insufficiency revealed in deafwaddler mice when tested for hearing loss and ataxia.
Hearing Loss
Modification of human hearing loss by plasma-membrane calcium pump PMCA2.
Hearing Loss
Plasma membrane Ca(2+)-ATPase: from a housekeeping function to a versatile signaling role.
Hearing Loss
The development, distribution and density of the plasma membrane calcium ATPase 2 calcium pump in rat cochlear hair cells.
Hearing Loss
The novel mouse mutation Oblivion inactivates the PMCA2 pump and causes progressive hearing loss.
Hearing Loss
The plasma membrane calcium ATPase and disease.
Hearing Loss
The plasma membrane calcium pump in the hearing process: physiology and pathology.
Hearing Loss
[Age-related expression of plasma membrane Ca(2+) -ATPase isoform 2 in the cochleas of C57BL/6J mice].
Hearing Loss, High-Frequency
Maintenance of neuronal size gradient in MNTB requires sound-evoked activity.
Hearing Loss, High-Frequency
The development, distribution and density of the plasma membrane calcium ATPase 2 calcium pump in rat cochlear hair cells.
Hearing Loss, Noise-Induced
Deficiency in plasma membrane calcium ATPase isoform 2 increases susceptibility to noise-induced hearing loss in mice.
Hearing Loss, Noise-Induced
[Protective effect of indirect activator of calcium pump on noise-induced hearing loss]
Heart Defects, Congenital
Molecular genetic analysis of the 3p- syndrome.
Heart Defects, Congenital
SERCA2a, phospholamban, sarcolipin, and ryanodine receptors gene expression in children with congenital heart defects.
Heart Diseases
Accelerated onset of heart failure in mice during pressure overload with chronically decreased SERCA2 calcium pump activity.
Heart Diseases
Calcium Upregulation by Percutaneous Administration of Gene Therapy in Cardiac Disease (CUPID): A Phase 2 Trial of Intracoronary Gene Therapy of Sarcoplasmic Reticulum Ca2+-ATPase in Patients With Advanced Heart Failure.
Heart Diseases
Circulating cytokine levels in mice with heart failure are etiology dependent.
Heart Diseases
Conditional mutations in SERCA, the Sarco-endoplasmic reticulum Ca(2+)-ATPase, alter heart rate and rhythmicity in Drosophila.
Heart Diseases
Conditional Up-Regulation of SERCA2a Exacerbates RyR2-Dependent Ventricular and Atrial Arrhythmias.
Heart Diseases
Design of a Phase 2b Trial of Intracoronary Administration of AAV1/SERCA2a in Patients With Advanced Heart Failure: The CUPID 2 Trial (Calcium Up-Regulation by Percutaneous Administration of Gene Therapy in Cardiac Disease Phase 2b).
Heart Diseases
Hypoxia and HIF-1 suppress SERCA2a expression in embryonic cardiac myocytes through two interdependent hypoxia response elements.
Heart Diseases
Left Ventricular Remodelling: A Problem in Search of Solutions.
Heart Diseases
Lnc'ing Ca2+, SERCA and cardiac disease.
Heart Diseases
Long Term Effects of AAV1/SERCA2a Gene Transfer in Patients with Severe Heart Failure: Analysis of Recurrent Cardiovascular Events and Mortality.
Heart Diseases
Role of cAMP in modulating relaxation kinetics and the force-frequency relation in mitral regurgitation heart failure.
Heart Diseases
Sarcoendoplasmic reticulum Ca(2+) ATPase. A critical target in chlorine inhalation-induced cardiotoxicity.
Heart Diseases
SERCA2 Haploinsufficiency in a Mouse Model of Darier Disease Causes a Selective Predisposition to Heart Failure.
Heart Diseases
SERCA2a gene therapy can improve symptomatic heart failure in delta-sarcoglycan deficient animals.
Heart Diseases
SPEG Controls Calcium Re-Uptake into the Sarcoplasmic Reticulum Through Regulating SERCA2a by Its Second Kinase-Domain.
Heart Diseases
Targeting sarcoplasmic reticulum calcium ATPase by gene therapy.
Heart Diseases
The emergence of plasma membrane calcium pump as a novel therapeutic target for heart disease.
Heart Diseases
The sarco-endoplasmic reticulum Ca2+ ATPase is required for development and muscle function in Caenorhabditis elegans.
Heart Diseases
[Biochemistry of myocardium taken at autopsy. Preliminary report]
Heart Failure
?-Arrestin2 Improves Post-Myocardial Infarction Heart Failure via Sarco[endo]plasmic Reticulum Ca(2+)-ATPase-Dependent Positive Inotropy in Cardiomyocytes.
Heart Failure
A human phospholamban promoter polymorphism in dilated cardiomyopathy alters transcriptional regulation by glucocorticoids.
Heart Failure
A pyridone derivative activates SERCA2a by attenuating the inhibitory effect of phospholamban.
Heart Failure
A SERCA2 pump with an increased Ca2+ affinity can lead to severe cardiac hypertrophy, stress intolerance and reduced life span.
Heart Failure
Accelerated onset of heart failure in mice during pressure overload with chronically decreased SERCA2 calcium pump activity.
Heart Failure
Acetylation of SERCA2a, Another Target for Heart Failure Treatment?
Heart Failure
Acute cellular actions of thyroid hormone and myocardial function.
Heart Failure
Acute heart failure--basic pathomechanism and new drug targets.
Heart Failure
Acute Inotropic and Lusitropic Effects of Cardiomyopathic R9C Mutation of Phospholamban.
Heart Failure
Adeno-associated virus-mediated expression of thyroid hormone receptor isoforms-alpha1 and -beta1 improves contractile function in pressure overload-induced cardiac hypertrophy.
Heart Failure
Adenoviral gene transfer of phospholamban in isolated rat cardiomyocytes. Rescue effects by concomitant gene transfer of sarcoplasmic reticulum Ca(2+)-ATPase.
Heart Failure
Adenoviral gene transfer of SERCA2a improves left-ventricular function in aortic-banded rats in transition to heart failure.
Heart Failure
Adenovirus gene transfer of SERCA in heart failure. A promising therapeutic approach ?
Heart Failure
Adenovirus-mediated gene transfer reconstitutes depressed sarcoplasmic reticulum Ca2+-ATPase levels and shortens prolonged cardiac myocyte Ca2+ transients.
Heart Failure
Adrenergic and muscarinic receptor regulation and therapeutic implications in heart failure.
Heart Failure
Advances in gene therapy for heart failure.
Heart Failure
Age-dependent suppression of SERCA2a mRNA in pediatric atrial myocardium.
Heart Failure
Alterations of phospholamban function can exhibit cardiotoxic effects independent of excessive sarcoplasmic reticulum Ca2+-ATPase inhibition.
Heart Failure
Altered force-frequency response in non-failing hearts with decreased SERCA pump-level.
Heart Failure
Altered sarcoplasmic reticulum Ca2+ ATPase gene expression in congestive heart failure: effect of chronic norepinephrine infusion.
Heart Failure
Ameliorated stress related proteins are associated with improved cardiac function by sarcoplasmic reticulum calcium ATPase gene transfer in heart failure.
Heart Failure
AQP4 knockout mice manifest abnormal expressions of calcium handling proteins possibly due to exacerbating pro-inflammatory factors in the heart.
Heart Failure
Astragalosides Rescue Both Cardiac Function and Sarcoplasmic Reticulum Ca(2+) Transport in Rats with Chronic Heart Failure.
Heart Failure
Augmentation of left ventricular mechanics by recirculation-mediated AAV2/1-SERCA2a gene delivery in experimental heart failure.
Heart Failure
Benefit of SERCA2a gene transfer to vascular endothelial and smooth muscle cells: a new aspect in therapy of cardiovascular diseases.
Heart Failure
Biventricular pacing cardiac contractility modulation improves cardiac contractile function via upregulating SERCA2 and miR-133 in a rabbit model of congestive heart failure.
Heart Failure
C33(S), a novel PDE9A inhibitor, protects against rat cardiac hypertrophy through upregulating cGMP signaling.
Heart Failure
Ca2+ uptake by the sarcoplasmic reticulum in ventricular myocytes of the SERCA2b/b mouse is impaired at higher Ca2+ loads only.
Heart Failure
Ca2+-ATPases in non-failing and failing heart: evidence for a novel cardiac sarco/endoplasmic reticulum Ca2+-ATPase 2 isoform (SERCA2c).
Heart Failure
Calcium cycling proteins and heart failure: mechanisms and therapeutics.
Heart Failure
Calcium pump overexpression and myocardial function. Implications for gene therapy of myocardial failure.
Heart Failure
Calcium pumps of plasma membrane and cell interior.
Heart Failure
Calcium signaling phenomena in heart diseases: a perspective.
Heart Failure
Calcium upregulation by percutaneous administration of gene therapy in cardiac disease (CUPID Trial), a first-in-human phase 1/2 clinical trial.
Heart Failure
Calcium Upregulation by Percutaneous Administration of Gene Therapy in Cardiac Disease (CUPID): A Phase 2 Trial of Intracoronary Gene Therapy of Sarcoplasmic Reticulum Ca2+-ATPase in Patients With Advanced Heart Failure.
Heart Failure
Calcium-induced delayed afterdepolarizations are triggered by dyadic subspace calcium affirming that increasing SERCA reduces aftercontractions.
Heart Failure
CaMKII?B mediates aberrant NCX1 expression and the imbalance of NCX1/SERCA in transverse aortic constriction-induced failing heart.
Heart Failure
cAMP-dependent protein kinase A-stimulated sarcoplasmic reticulum function in heart failure.
Heart Failure
cAMP-mediated signal transduction and sarcoplasmic reticulum function in heart failure.
Heart Failure
Cardiac contractility modulation improves left ventricular systolic function partially via miR-25 mediated SERCA2A expression in rabbit trans aortic constriction heart failure model.
Heart Failure
Cardiac expression of sarcoplasmic reticulum calcium ATPase in fetuses with trisomy 21 and trisomy 18 presenting with nuchal translucency.
Heart Failure
Cardiac function evaluation for a novel one-step detoxification product of Aconiti Lateralis Radix Praeparata.
Heart Failure
Cardiac gene therapy with SERCA2a: From bench to bedside.
Heart Failure
Cardiac SERCA2A/B: therapeutic targets for heart failure.
Heart Failure
Cardiac surgical delivery of the sarcoplasmic reticulum calcium ATPase rescues myocytes in ischemic heart failure.
Heart Failure
Cardiac-specific overexpression of sarcolipin inhibits sarco(endo)plasmic reticulum Ca2+ ATPase (SERCA2a) activity and impairs cardiac function in mice.
Heart Failure
Cardiomyocyte-specific disruption of Serca2 in adult mice causes sarco(endo)plasmic reticulum stress and apoptosis.
Heart Failure
Cardioprotective effect of salvianolic acid B on large myocardial infarction mediated by reversing upregulation of leptin, endothelin pathways, and abnormal expression of SERCA2a, phospholamban in rats.
Heart Failure
Cardioprotective Effects of Serca2a Overexpression Against Ischemiareperfusion- induced Injuries in Rats.
Heart Failure
Changes in intracellular Na+ in heart failure following SERCA knockout--more of a solution or more of a problem?
Heart Failure
Changes in skeletal muscle SR Ca2+ pump in congestive heart failure due to myocardial infarction are prevented by angiotensin II blockade.
Heart Failure
Chronic phospholamban-sarcoplasmic reticulum calcium ATPase interaction is the critical calcium cycling defect in dilated cardiomyopathy.
Heart Failure
Circulating Sphingosine-1-Phosphate as A Non-Invasive Biomarker of Heart Transplant Rejection.
Heart Failure
Combining SERCA2a activation and Na-K ATPase inhibition: a promising new approach to managing acute heart failure syndromes with low cardiac output.
Heart Failure
Comparative analysis of parvalbumin and SERCA2a cardiac myocyte gene transfer in a large animal model of diastolic dysfunction.
Heart Failure
Comparison of heart sarcolemmal enzyme activities in normal and cardiomyopathic (UM-X7.1) hamsters.
Heart Failure
Compartmentalized expression of three novel sarco/endoplasmic reticulum Ca2+ATPase 3 isoforms including the switch to ER stress, SERCA3f, in non-failing and failing human heart.
Heart Failure
Compensatory asymmetry in down-regulation and inhibition of the myocardial Ca2+ cycle in congestive heart failure produced in dogs by idiopathic dilated cardiomyopathy and rapid ventricular pacing.
Heart Failure
Compromised Myocardial Energetics in Hypertrophied Mouse Hearts Diminish the Beneficial Effect of Overexpressing SERCA2a.
Heart Failure
Constitutive cardiac overexpression of sarcoplasmic/endoplasmic reticulum Ca2+-ATPase delays myocardial failure after myocardial infarction in rats at a cost of increased acute arrhythmias.
Heart Failure
Contractile Behavior of Mouse Aorta Depends on SERCA2 Isoform Distribution: Effects of Replacing SERCA2a by SERCA2b.
Heart Failure
Contribution of abnormal sarcoplasmic reticulum ATPase activity to systolic and diastolic dysfunction in human heart failure.
Heart Failure
Control of protein expression through mRNA stability in calcium signalling.
Heart Failure
Correcting Calcium Dysregulation in Chronic Heart Failure Using SERCA2a Gene Therapy.
Heart Failure
Correction to: Role of SIRT1 in Modulating Acetylation of the Sarco- Endoplasmic Reticulum Ca2+-ATPase in Heart Failure.
Heart Failure
CYP2J2-derived epoxyeicosatrienoic acids suppress endoplasmic reticulum stress in heart failure.
Heart Failure
Cytosolic H2O2 mediates hypertrophy, apoptosis and decreased SERCA activity in mice with chronic hemodynamic overload.
Heart Failure
Darier disease is associated with heart failure: a cross-sectional case-control and population based study.
Heart Failure
Differential expression of sarcolipin protein during muscle development and cardiac pathophysiology.
Heart Failure
Dilated cardiomyopathy and sudden death resulting from constitutive activation of protein kinase a.
Heart Failure
Diminished posttetanic potentiation in failing human myocardium.
Heart Failure
Direct detection of SERCA calcium transport and small-molecule inhibition in giant unilamellar vesicles.
Heart Failure
Down-regulation of FKBP12.6 and SERCA2a contributes to acute heart failure in septic shock and is related to an up-regulated endothelin signalling pathway.
Heart Failure
Downregulation of sarcoplasmic reticulum Ca(2+)-ATPase during progression of left ventricular hypertrophy.
Heart Failure
Drug Interactions With the Ca2+-ATPase From Sarco(Endo)Plasmic Reticulum (SERCA).
Heart Failure
E3 Ubiquitin ligase NEDD4 family?regulatory network in cardiovascular disease.
Heart Failure
Early expression of natriuretic peptides and SERCA in mild heart failure: association with severity of the disease.
Heart Failure
Effect of angiotensin-converting enzyme inhibition on protein kinase C and SR proteins in heart failure.
Heart Failure
Effect of Valsartan on Sarcoplasmic Reticulum Ca2+-ATPase Pump of the Left Ventricular Myocardium in Rats with Heart Failure with Preserved Ejection Fraction.
Heart Failure
Effects of inhibition of sarcoplasmic reticulum calcium uptake on contraction in myocytes isolated from failing human ventricle.
Heart Failure
Effects of mutant and antisense RNA of phospholamban on SR Ca(2+)-ATPase activity and cardiac myocyte contractility.
Heart Failure
Elevated afterload, neuroendocrine stimulation, and human heart failure increase BNP levels and inhibit preload-dependent SERCA upregulation.
Heart Failure
Elevated sarcoplasmic reticulum Ca2+ leak in intact ventricular myocytes from rabbits in heart failure.
Heart Failure
Endomyocardial gene expression during development of pacing tachycardia-induced heart failure in the dog.
Heart Failure
Endothelin receptor antagonist CPU0213 and vitamin E reverse downregulation of FKBP12.6 and SERCA2a: a role of hyperphosphorylation of PKCepsilon.
Heart Failure
Enhanced phosphorylation of phospholamban and downregulation of sarco/endoplasmic reticulum Ca2+ ATPase type 2 (SERCA 2) in cardiac sarcoplasmic reticulum from rabbits with heart failure.
Heart Failure
Epigallocatechin-3 gallate prevents pressure overload-induced heart failure by up-regulating SERCA2a via histone acetylation modification in mice.
Heart Failure
Evidence for calcineurin-mediated regulation of SERCA 2a activity in human myocardium.
Heart Failure
Excessive sarcoplasmic/endoplasmic reticulum Ca2+-ATPase expression causes increased sarcoplasmic reticulum Ca2+ uptake but decreases myocyte shortening.
Heart Failure
Exercise training prior to cardiac-specific Serca2 disruption attenuates the decline in cardiac function in mice.
Heart Failure
Expression of A-, B-, and C-type natriuretic peptide genes in failing and developing human ventricles. Correlation with expression of the Ca(2+)-ATPase gene.
Heart Failure
Expression of skeletal muscle sarcoplasmic reticulum calcium-ATPase is reduced in rats with postinfarction heart failure.
Heart Failure
Fine-tuning SERCA activity to treat distinct heart failure syndromes.
Heart Failure
Frequency-dependent contractile strength in mice over- and underexpressing the sarco(endo)plasmic reticulum calcium-ATPase.
Heart Failure
Function and regulation of sarcoplasmic reticulum Ca2+-ATPase: advances during the past decade and prospects for the coming decade.
Heart Failure
Gender influences on sarcoplasmic reticulum Ca2+-handling in failing human myocardium.
Heart Failure
Gene therapy for heart failure.
Heart Failure
Gene therapy for heart failure: where do we stand?
Heart Failure
Gene therapy in heart failure. SERCA2a as a therapeutic target.
Heart Failure
Gene transfer of a phospholamban-targeted antibody improves calcium handling and cardiac function in heart failure.
Heart Failure
GL Brown Prize Lecture Matters of the Heart: The Physiology of Cardiac Function and Failure.
Heart Failure
Glycogen synthase kinase-3beta regulates growth, calcium homeostasis, and diastolic function in the heart.
Heart Failure
Hemodynamics and mitochondrial energy metabolism in right heart hypertrophy after acute hypoxic stress.
Heart Failure
Heterozygous disruption of SERCA2a is not associated with impairment of cardiac performance in humans: implications for SERCA2a as a therapeutic target in heart failure.
Heart Failure
HIF-1 regulation of miR-29c impairs SERCA2 expression and cardiac contractility.
Heart Failure
High resolution mapping of the cardiac transmural proteome using reverse phase protein microarrays.
Heart Failure
Highly cooperative dependence of sarco/endoplasmic reticulum calcium ATPase (SERCA) 2a pump activity on cytosolic calcium in living cells.
Heart Failure
HuR regulates phospholamban expression in isoproterenol-induced cardiac remodeling.
Heart Failure
Hydralazine-induced promoter demethylation enhances sarcoplasmic reticulum Ca(2+)-ATPase and calcium homeostasis in cardiac myocytes.
Heart Failure
Hypoxia-driven sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (SERCA2) downregulation depends on low-density lipoprotein receptor-related protein 1 (LRP1)-signalling in cardiomyocytes.
Heart Failure
Identification of Small Ankyrin 1 as a Novel Sarco(endo)plasmic Reticulum Ca2+-ATPase 1 (SERCA1) Regulatory Protein in Skeletal Muscle.
Heart Failure
Immunohistochemical evidence for expression of fast-twitch type sarco(endo)plasmic reticulum Ca(2+) ATPase (SERCA1) in German shepherd dogs with dilated cardiomyopathy myocardium.
Heart Failure
Immunosuppression Decreases Inflammation and Increases AAV6-hSERCA2a-Mediated SERCA2a Expression.
Heart Failure
Impact of oxidative posttranslational modifications of SERCA2 on heart failure exacerbation in young patients with non-ischemic cardiomyopathy: A pilot study.
Heart Failure
Impaired Ca2+-ATPase oligomerization and increased phospholamban expression in dilated cardiomyopathy.
Heart Failure
Importance of SERCA2a on early isolated diastolic dysfunction induced by supravalvular aortic stenosis in rats.
Heart Failure
Improved cardiac function after sarcoplasmic reticulum Ca(2+)-ATPase gene transfer in a heart failure model induced by chronic myocardial ischaemia.
Heart Failure
Improved exercise capacity and reduced systemic inflammation after adenoviral-mediated SERCA-2a gene transfer.
Heart Failure
Improved systolic function of rat cardiocytes during heart failure by overexpression of SERCA2a.
Heart Failure
Improvement in cardiac function after sarcoplasmic reticulum Ca2+-ATPase gene transfer in a beagle heart failure model.
Heart Failure
Improvement in survival and cardiac metabolism after gene transfer of sarcoplasmic reticulum Ca(2+)-ATPase in a rat model of heart failure.
Heart Failure
Improving cardiac Ca?² transport into the sarcoplasmic reticulum in heart failure: lessons from the ubiquitous SERCA2b Ca?² pump.
Heart Failure
In vitro selection and characterization of DNA aptamers specific for phospholamban.
Heart Failure
In vivo effects of nitrosyl hydrogen on cardiac function and sarcoplasmic reticulum calcium pump (SERCA2a) in rats with heart failure after myocardial infarction.
Heart Failure
Increased Ca2+ sensitivity and protein expression of SERCA 2a in situations of chronic beta3-adrenoceptor deficiency.
Heart Failure
Increased FOG-2 in failing myocardium disrupts thyroid hormone-dependent SERCA2 gene transcription.
Heart Failure
Increased nitration of sarcoplasmic reticulum Ca2+-ATPase in human heart failure.
Heart Failure
Increased SR Ca2+ cycling contributes to improved contractile performance in SERCA2a-overexpressing transgenic rats.
Heart Failure
Influence of long-term treatment of imidapril on mortality, cardiac function, and gene expression in congestive heart failure due to myocardial infarction.
Heart Failure
Influences of increased expression of the Ca2+ ATPase of the sarcoplasmic reticulum by a transgenic approach on cardiac contractility.
Heart Failure
Inhibition of carnitine synthesis modulates protein contents of the cardiac sarcoplasmic reticulum Ca2+-ATPase and hexokinase type I in rat hearts with myocardial infarction.
Heart Failure
Interleukin-17 upregulation participates in the pathogenesis of heart failure in mice via NF-?B-dependent suppression of SERCA2a and Cav1.2 expression.
Heart Failure
Interleukin-6-induced reciprocal expression of SERCA and natriuretic peptides mRNA in cultured rat ventricular myocytes.
Heart Failure
Intramyocardial injection of SERCA2a-expressing lentivirus improves myocardial function in doxorubicin-induced heart failure.
Heart Failure
Investigation of the safety and feasibility of AAV1/SERCA2a gene transfer in patients with chronic heart failure supported with a left ventricular assist device - the SERCA-LVAD TRIAL.
Heart Failure
Isoenzyme-selective regulation of SERCA2 gene expression by protein kinase C in neonatal rat ventricular myocytes.
Heart Failure
Istaroxime stimulates SERCA2a and accelerates calcium cycling in heart failure by relieving phospholamban inhibition.
Heart Failure
LabHEART: an interactive computer model of rabbit ventricular myocyte ion channels and Ca transport.
Heart Failure
Left ventricular mechanical and energetic changes in long-term isoproterenol-induced hypertrophied hearts of SERCA2a transgenic rats.
Heart Failure
Left ventricular SERCA2a gene down-regulation does not parallel ANP gene up-regulation during post-MI remodelling in rats.
Heart Failure
Lentiviral vector-mediated SERCA2 gene transfer protects against heart failure and left ventricular remodeling after myocardial infarction in rats.
Heart Failure
Limited functional and metabolic improvements in hypertrophic and healthy rat heart overexpressing the skeletal muscle isoform of SERCA1 by adenoviral gene transfer in vivo.
Heart Failure
Local energetic regulation of sarcoplasmic and myosin ATPase is differently impaired in rats with heart failure.
Heart Failure
Long Term Effects of AAV1/SERCA2a Gene Transfer in Patients with Severe Heart Failure: Analysis of Recurrent Cardiovascular Events and Mortality.
Heart Failure
Matters of the heart: the physiology of cardiac function and failure.
Heart Failure
Mechanisms of altered excitation-contraction coupling in canine tachycardia-induced heart failure, II: model studies.
Heart Failure
Messenger RNA expression and immunological quantification of phospholamban and SR-Ca(2+)-ATPase in failing and nonfailing human hearts.
Heart Failure
miR-132/212 Impairs Cardiomyocytes Contractility in the Failing Heart by Suppressing SERCA2a.
Heart Failure
miR-25 Tough Decoy Enhances Cardiac Function in Heart Failure.
Heart Failure
Moderate heart dysfunction in mice with inducible cardiomyocyte-specific excision of the Serca2 gene.
Heart Failure
Modulation of rabbit muscle sarcoplasmic reticulum Ca(2+)-ATPase activity by novel quercetin derivatives.
Heart Failure
Modulation of SERCA: implications for the failing human heart.
Heart Failure
Modulation of vascular sarco/endoplasmic reticulum calcium ATPase in cardiovascular pathophysiology.
Heart Failure
Molecular cloning and analysis of the human cardiac sarco(endo)plasmic reticulum Ca(2+)-ATPase (SERCA2) gene promoter.
Heart Failure
Myeloid-Derived Growth Factor Protects Against Pressure Overload-Induced Heart Failure by Preserving Sarco/Endoplasmic Reticulum Ca2+-ATPase Expression in Cardiomyocytes.
Heart Failure
New insights into SERCA2a gene therapy in heart failure: pay attention to the negative effects of B-type natriuretic peptides.
Heart Failure
Novel therapies in acute and chronic heart failure.
Heart Failure
Observations on atrial natriuretic peptide, sympathetic activity and renal Ca2+ pump in diabetic and hypertensive rats.
Heart Failure
Ophiopogonin D Increases SERCA2a Interaction with Phospholamban by Promoting CYP2J3 Upregulation.
Heart Failure
Overexpression of Sarcoendoplasmic Reticulum Calcium ATPase 2a Promotes Cardiac Sympathetic Neurotransmission via Abnormal Endoplasmic Reticulum and Mitochondria Ca(2+) Regulation.
Heart Failure
Overwhelming evidence of the beneficial effects of SERCA gene transfer in heart failure.
Heart Failure
Pak1 is required to maintain ventricular Ca²? homeostasis and electrophysiological stability through SERCA2a regulation in mice.
Heart Failure
Phospholamban ablation in hearts expressing the high affinity SERCA2b isoform normalizes global Ca²? homeostasis but not Ca²?-dependent hypertrophic signaling.
Heart Failure
Phospholamban Ablation Using CRISPR/Cas9 System Improves Mortality in a Murine Heart Failure Model.
Heart Failure
Phospholamban degradation is induced by phosphorylation-mediated ubiquitination and inhibited by interaction with cardiac type Sarco(endo)plasmic reticulum Ca(2+)-ATPase.
Heart Failure
Phospholamban mutants compete with wild type for SERCA binding in living cells.
Heart Failure
Phospholamban phosphorylation, mutation, and structural dynamics: a biophysical approach to understanding and treating cardiomyopathy.
Heart Failure
Phospholamban, a predicted candidate for early cardiac problem detection using signal processing techniques.
Heart Failure
Phospholamban: a crucial regulator of cardiac contractility.
Heart Failure
Phospholamban: a promising therapeutic target in heart failure?
Heart Failure
Phosphorylated phospholamban stabilizes a compact conformation of the cardiac calcium-ATPase.
Heart Failure
Phosphorylation and binding of AUF1 to the 3'-untranslated region of cardiomyocyte SERCA2a mRNA.
Heart Failure
Physiological effects of adenoviral gene transfer of sarcoplasmic reticulum calcium ATPase in isolated rat myocytes.
Heart Failure
Plasma membrane Ca2+-ATPase isoform 4 antagonizes cardiac hypertrophy in association with calcineurin inhibition in rodents.
Heart Failure
Polymorphic SERCA2a variants do not account for inter-individual differences in phospholamban-SERCA2a interactions in human heart failure.
Heart Failure
Post-translational Modifications in Heart Failure: Small Changes, Big Impact.
Heart Failure
Potential of gene therapy as a treatment for heart failure.
Heart Failure
Prevalence of AAV1 neutralizing antibodies and consequences for a clinical trial of gene transfer for advanced heart failure.
Heart Failure
Primary Effect of SERCA 2a Gene Transfer on Conduction Reserve in Chronic Myocardial Infarction.
Heart Failure
Prominent heart organ-level performance deficits in a genetic model of targeted severe and progressive SERCA2 deficiency.
Heart Failure
Protective effect of oxymatrine on chronic rat heart failure.
Heart Failure
Protective effect of the endothelin antagonist CPU0213 against isoprenaline-induced heart failure by suppressing abnormal expression of leptin, calcineurin and SERCA2a in rats.
Heart Failure
PYK2 regulates SERCA2 gene expression in neonatal rat ventricular myocytes.
Heart Failure
Redox-Resistant SERCA [Sarco(endo)plasmic Reticulum Calcium ATPase] Attenuates Oxidant-Stimulated Mitochondrial Calcium and Apoptosis in Cardiac Myocytes and Pressure Overload-Induced Myocardial Failure in Mice.
Heart Failure
Reduced Ca(2+)-sensitivity of SERCA 2a in failing human myocardium due to reduced serin-16 phospholamban phosphorylation.
Heart Failure
Reduced cardiac myosin adenosinetriphosphatase activity in dogs with spontaneously occurring heart failure.
Heart Failure
Reduced level of serine(16) phosphorylated phospholamban in the failing rat myocardium: a major contributor to reduced SERCA2 activity.
Heart Failure
Regional diastolic dysfunction in post-infarction heart failure: role of local mechanical load and SERCA expression.
Heart Failure
Regional Differences in the Ghrelin-Growth Hormone Secretagogue Receptor Signalling System in Human Heart Disease.
Heart Failure
Regulation of expression of cardiac sarcoplasmic reticulum proteins under pathophysiological conditions.
Heart Failure
Regulation of myocardial SERCA2a expression in ventricular hypertrophy and heart failure.
Heart Failure
Regulation of SERCA pumps expression in diabetes.
Heart Failure
Regulation of the sarcoplasmic reticulum Ca2+-ATPase expression in the hypertrophic and failing heart.
Heart Failure
Research on the Effects of the Chronic Treatment With Different Doses of Urocortin 2 in Heart Failure Rats.
Heart Failure
Restoration of contractile function in isolated cardiomyocytes from failing human hearts by gene transfer of SERCA2a.
Heart Failure
Restoration of sarcoplasmic reticulum protein level by thyroid hormone contributes to partial improvement of myocardial function, but not to glucose metabolism in an early failing heart.
Heart Failure
Retraction. The correlation between angiogenesis and abnormal expression of SERCA2a, phospholamban and the endothelin pathway in heart failure, and improvement by puerarin.
Heart Failure
Reversal of cardiac dysfunction after long-term expression of SERCA2a by gene transfer in a pre-clinical model of heart failure.
Heart Failure
Rg3 promotes the SUMOylation of SERCA2a and corrects cardiac dysfunction in heart failure.
Heart Failure
Right Ventricular Beneficial Effects of Intracoronary SERCA2a Gene Transfer in an Experimental Model of Heart Failure.
Heart Failure
Role of Reduced Sarco-Endoplasmic Reticulum Ca2+-ATPase Function on Sarcoplasmic Reticulum Ca2+ Alternans in the Intact Rabbit Heart.
Heart Failure
Role of SIRT1 in Modulating Acetylation of the Sarco-Endoplasmic Reticulum Ca2+-ATPase in Heart Failure.
Heart Failure
Role of SR Ca2+-ATPase in contractile dysfunction of myocytes in tachycardia-induced heart failure.
Heart Failure
Role of the PRC2-Six1-miR-25 signaling axis in heart failure.
Heart Failure
Sarco(endo)plasmic Reticulum Calcium ATPase (SERCA) Inhibition by Sarcolipin Is Encoded in Its Luminal Tail.
Heart Failure
Sarcoendoplasmic reticulum calcium transport ATPase 2a: a potential gene therapy target in heart failure.
Heart Failure
Sarcolipin and phospholamban inhibit the calcium pump by populating a similar metal ion-free intermediate state.
Heart Failure
Sarcoplasmic reticular Ca2+ pump ATPase activity in congestive heart failure due to myocardial infarction.
Heart Failure
Sarcoplasmic reticulum adenosine triphosphatase overexpression in the L-type Ca2+ channel mouse results in cardiomyopathy and Ca2+ -induced arrhythmogenesis.
Heart Failure
Sarcoplasmic reticulum ATPase activity in type I and II skeletal muscle fibres of chronic heart failure patients.
Heart Failure
Sarcoplasmic reticulum Ca(2+) ATPase as a therapeutic target for heart failure.
Heart Failure
Sarcoplasmic reticulum Ca(2+)-ATPase overexpression by adenovirus mediated gene transfer and in transgenic mice.
Heart Failure
Sarcoplasmic Reticulum Ca-ATPase and Heart Failure 20 Years Later.
Heart Failure
Sarcoplasmic reticulum Ca2+ ATPase gene expression to the rescue of myocardial contractility in hypothyroid associated heart failure.
Heart Failure
Sarcoplasmic reticulum calcium mishandling: central tenet in heart failure?
Heart Failure
Sensitivity analysis revealing the effect of modulating ionic mechanisms on calcium dynamics in simulated human heart failure.
Heart Failure
SERCA in genesis of arrhythmias: what we already know and what is new?
Heart Failure
SERCA in heterogeneity of diastolic dysfunction in post-infarction heart failure with reduced ejection fraction.
Heart Failure
SERCA pump isoforms: their role in calcium transport and disease.
Heart Failure
SERCA pump level is a critical determinant of Ca(2+)homeostasis and cardiac contractility.
Heart Failure
SERCA pumps and human diseases.
Heart Failure
SERCA2 Haploinsufficiency in a Mouse Model of Darier Disease Causes a Selective Predisposition to Heart Failure.
Heart Failure
SERCA2a gene therapy can improve symptomatic heart failure in delta-sarcoglycan deficient animals.
Heart Failure
SERCA2a gene therapy for heart failure: ready for primetime?
Heart Failure
SERCA2a gene therapy in heart failure: an anti-arrhythmic positive inotrope.
Heart Failure
SERCA2a gene therapy restores microRNA-1 expression in heart failure via an Akt/FoxO3A-dependent pathway.
Heart Failure
SERCA2a Gene Transfer Decreases SR Calcium Leak and Reduces Ventricular Arrhythmias in a Model of Chronic Heart Failure.
Heart Failure
SERCA2a in heart failure: role and therapeutic prospects.
Heart Failure
SERCA2a, a Potential Gene Therapy Target in Heart Failure.
Heart Failure
SERCA2a-phospholamban interaction monitored by an interposed circularly permutated green fluorescent protein.
Heart Failure
SERCA2a: a key protein in the Ca2+ cycle of the heart failure.
Heart Failure
SERCA2a: a prime target for modulation of cardiac contractility during heart failure.
Heart Failure
Serendipitous discovery of a novel protein signaling mechanism in heart failure.
Heart Failure
Short-term effects of ?2-AR blocker ICI 118,551 on sarcoplasmic reticulum SERCA2a and cardiac function of rats with heart failure.
Heart Failure
Simvastatin prevents decreased SERCA2a activity in non-ischemic heart failure in rabbits via inhibition of ?-adrenergic signaling.
Heart Failure
Skeletal muscle sarcoplasmic reticulum Ca(2+)-ATPase gene expression in congestive heart failure.
Heart Failure
Sleeve gastrectomy in obese Wistar rats improves diastolic function and promotes cardiac recovery independent of weight loss.
Heart Failure
Small-molecule activation of SERCA2a SUMOylation for the treatment of heart failure.
Heart Failure
Sodium Accumulation in SERCA Knockout-Induced Heart Failure.
Heart Failure
Sodium accumulation promotes diastolic dysfunction in end-stage heart failure following Serca2 knockout.
Heart Failure
SPEG Controls Calcium Re-Uptake into the Sarcoplasmic Reticulum Through Regulating SERCA2a by Its Second Kinase-Domain.
Heart Failure
Structures of the heart specific SERCA2a Ca2+-ATPase.
Heart Failure
SUMO1-dependent modulation of SERCA2a in heart failure.
Heart Failure
Targeted overexpression of the sarcoplasmic reticulum Ca2+-ATPase increases cardiac contractility in transgenic mouse hearts.
Heart Failure
Targeted sarcoplasmic reticulum Ca2+ ATPase 2a gene delivery to restore electrical stability in the failing heart.
Heart Failure
Targeting phospholamban by gene transfer in human heart failure.
Heart Failure
Targeting protein-protein interactions for therapeutic discovery via FRET-based high-throughput screening in living cells.
Heart Failure
Targeting sarcoplasmic reticulum calcium ATPase by gene therapy.
Heart Failure
Targeting SERCA2a as an innovative approach to the therapy of congestive heart failure.
Heart Failure
The cardiac sarcoplasmic/endoplasmic reticulum calcium ATPase: a potent target for cardiovascular diseases.
Heart Failure
The correlation between angiogenesis and abnormal expression of SERCA2a, phospholamban and the endothelin pathway in heart failure, and improvement by puerarin.
Heart Failure
The Current and Future Landscape of SERCA Gene Therapy for Heart Failure: A Clinical Perspective.
Heart Failure
The DWORF micropeptide enhances contractility and prevents heart failure in a mouse model of dilated cardiomyopathy.
Heart Failure
The effects of a thyroid hormone analog on left ventricular performance and contractile and calcium cycling proteins in the baboon.
Heart Failure
The Ku protein complex interacts with YY1, is up-regulated in human heart failure, and represses alpha myosin heavy-chain gene expression.
Heart Failure
The regulation of sarco(endo)plasmic reticulum calcium-ATPases (SERCA).
Heart Failure
The relative phospholamban and SERCA2 ratio: a critical determinant of myocardial contractility.
Heart Failure
The role of CaMKII regulation of phospholamban activity in heart disease.
Heart Failure
The role of phospholamban and GSK3 in regulating rodent cardiac SERCA function.
Heart Failure
The Role of SUMO-1 in Cardiac Oxidative Stress and Hypertrophy.
Heart Failure
The sarcoplasmic reticulum Ca2+-ATPase (SERCA2) gene promoter activity is decreased in response to severe left ventricular pressure-overload hypertrophy in rat hearts.
Heart Failure
The transmembrane peptide DWORF activates SERCA2a via dual mechanisms.
Heart Failure
The war against heart failure: the Lancet lecture.
Heart Failure
Thyroxine increases Serca2 and Ryr2 gene expression in heart failure rats with euthyroid sick syndrome.
Heart Failure
Tight interplay between the Ca2+ affinity of the cardiac SERCA2 Ca2+ pump and the SERCA2 expression level.
Heart Failure
Toll-Like Receptor 9 Promotes Survival in SERCA2a KO Heart Failure Mice.
Heart Failure
Transcriptional changes following restoration of SERCA2a levels in failing rat hearts.
Heart Failure
Transgenic expression of sarcoplasmic reticulum Ca(2+) atpase modifies the transition from hypertrophy to early heart failure.
Heart Failure
Transgenic mouse models for cardiac dysfunction by a specific gene manipulation.
Heart Failure
Transgenic rat hearts overexpressing SERCA2a show improved contractility under baseline conditions and pressure overload.
Heart Failure
Tumor necrosis factor-alpha decreases sarcoplasmic reticulum Ca2+-ATPase expressions via the promoter methylation in cardiomyocytes*
Heart Failure
Two-variable nullcline analysis of ionic general equilibrium predicts calcium homeostasis in ventricular myocytes.
Heart Failure
Upregulation of leptin pathway correlates with abnormal expression of SERCA2a, phospholamban and the endothelin pathway in heart failure and reversal by CPU86017.
Heart Failure
Velvet Antler Ameliorates Cardiac Function by Restoring Sarcoplasmic Reticulum Ca2+-ATPase Activity in Rats With Heart Failure After Myocardial Infarction.
Heart Failure
Weighing in on heart failure: the role of SERCA2a SUMOylation.
Heart Failure
[Abnormal abundances of calcium cycling regulatory proteins in rabbit myocytes with heart failure]
Heart Failure
[Abnormal calcium re-uptake in myocardium sarcoplasmic reticulum in rabbits with heart failure and the influencing factors].
Heart Failure
[Adeno-associated viral gene transfer of SERCA2a improves heart function in chronic congestive heart failure rats]
Heart Failure
[Bone marrow stem cells-based SERCA2a gene therapy for heart failure after acute myocardium infarction]
Heart Failure
[Calcium kinetics in the progression of heart failure]
Heart Failure
[Changes of sarcolemma Na+/K+ ATPase and sarcoplasmic reticulum membrane Ca2+ ATPase activity after stem cell transplantation in chronic heart failure]
Heart Failure
[Effect of losartan on sarcoplasmic reticulum Ca2+ handing proteins in heart failure rabbit]
Heart Failure
[Effect of Yixinshu Capsules on calcium regulatory protein in cardiac myocytes of rats with heart failure].
Heart Failure
[Effects of Astragalus membranaccus on cardiac function and SERCA2a gene expression in myocardial tissues of rats with chronic heart failure]
Heart Failure
[Effects of curcumin on sarcoplasmic reticulum Ca2+-ATPase in rabbits with heart failure]
Heart Failure
[Effects of valsartan on sarcoplasmic reticulum calcium adenodine triphosphatase, protein kinase A and protein phosphatase 1 alpha in a rabbit model of heart failure]
Heart Failure
[Expressions of SERCA2a and miR-25-3p/5p in myocardium of rats with heart failure and therapeutic effects of Xiefei Lishui recipe].
Heart Failure
[Gene therapy in heart failure: the unexpected results from the CUPID 2 trial].
Heart Failure
[Genetic complementation studies using genetically engineered mice have revealed the impact of phospholamban on progression of cardiomyopathy]
Heart Failure
[Molecular mechanism of the changes in ventricular electrical remodeling caused by mechano-electrical feedback in rabbits with congestive heart failure]
Heart Failure
[Myocardial metabolism of calcium in heart failure: from physiology to new therapeutic perspectives]
Heart Failure
[Overexpression of sarcoplasmic reticulum calcium ATPase induced hemodynamic and proteomic changes in a dog model of heart failure]
Heart Failure
[Preliminary study on mechanism of electroacupuncture with the involvement of SERCA2a/PLB on the synergistic and attenuated effect of aconitine in treatment of heart failure].
Heart Failure
[Research progress of sarcolipin-a new regulatory protein of sarcoplasmic reticulum Ca2+ ATPase].
Heart Failure
[The effect of the relative amount of sarcoplasmic reticulum Ca2+ -ATPase on the cardiac contractile and relaxation function]
Heart Failure
[The mechanism of contractile dysfunction in heart failure, focussing on SERCA2a function]
Heart Failure
[Treatment of chronic heart failure by overexpressing sarcoplasmic reticulum calcium ATPase through gene therapy: an experiment with rats]
Heart Failure, Diastolic
Plasma levels of tumor necrosis factor-? and interleukin-6 are associated with diastolic heart failure through downregulation of sarcoplasmic reticulum Ca2+ ATPase.
Heart Failure, Diastolic
Sustained Toll-Like Receptor 9 Activation Promotes Systemic and Cardiac Inflammation, and Aggravates Diastolic Heart Failure in SERCA2a KO Mice.
Heart Rupture
N-acetyl-seryl-aspartyl-lysyl-proline treatment protects heart against excessive myocardial injury and heart failure in mice.
Heart Valve Diseases
Analysis of azide-insensitive Ca2+-dependent ATPase activity in atrial specimens from patients with coronary or valvular heart disease.
Heart Valve Diseases
E3 Ubiquitin ligase NEDD4 family?regulatory network in cardiovascular disease.
Hepatic Encephalopathy
Ammonium increases Ca(2+) signalling and up-regulates expression of TRPC1 gene in astrocytes in primary cultures and in the in vivo brain.
Hepatitis
ADENOSINETRIPHOSPHATASE OF LIVER MITOCHONDRIA IN VIRUS HEPATITIS OF MICE.
Hepatitis
[Lactate dehydrogenase, glucosephosphate dehydrogenase, glutathione reductase and adenosine triphosphatase activities in the erythrocytes of patients with acute viral hepatitis]
Hepatitis B
Hepatitis B virus-related insertional mutagenesis implicates SERCA1 gene in the control of apoptosis.
Hepatolenticular Degeneration
ATP-dependent copper transporter, in the Golgi apparatus of rat hepatocytes, transports Cu(II) not Cu(I).
Hernias, Diaphragmatic, Congenital
Myocardium expression of connexin 43, SERCA2a, and myosin heavy chain isoforms are preserved in nitrofen-induced congenital diaphragmatic hernia rat model.
Herpes Zoster
Neuronal nitric oxide synthase signaling in the heart is regulated by the sarcolemmal calcium pump 4b.
Herpes Zoster
[Action of adenosinetriphosphatase on zona.]
Huntington Disease
Evaluating the SERCA2 and VEGF mRNAs as Potential Molecular Biomarkers of the Onset and Progression in Huntington's Disease.
Hypercalcemia
Ca2+-dependent phosphatase and Ca2+-dependent ATPase activities in plasma membranes of eel gill epithelium--III. Stimulation of branchial high-affinity Ca2+-ATPase activity during prolactin-induced hypercalcemia in American eels.
Hypercalcemia
Calcitropic actions of prolactin in freshwater North American eel (Anguilla rostrata LeSueur).
Hypercholesterolemia
Targeting the redox regulation of SERCA in vascular physiology and disease.
Hypercholesterolemia
[Change in the molecular properties of sarcoplasmic reticulum Ca-ATPase during modification of the membranes with cholesterol]
Hypercholesterolemia
[Effect of cholesterol on the cooperativeness of the Ca-ATPase of the sarcoplasmic reticulum in rabbit skeletal muscle]
Hypercholesterolemia
[Lipid peroxidation as a major factor in the modification of the catalytic function of Ca-ATPase of the sarcoplasmic reticulum in hypercholesterolemia]
Hypercholesterolemia
[Modification of the functional properties of sarcoplasmic reticulum Ca-ATPase in hypercholesterolemia]
Hypercholesterolemia
[Protective effect of alpha-tocopherol on the Ca2+-transport system of the sarcoplasmic reticulum membranes in hypercholesterolemia]
Hypercholesterolemia
[Role of lipid peroxidation in changes in the structure of Ca-ATPase in skeletal muscle sarcoplasmic reticulum during hypercholesterolemia]
Hypercholesterolemia
[Several properties of the Ca-pump of rabbit skeletal muscle sarcoplasmic reticulum in hypercholesteremia]
Hypercholesterolemia
[Spin labels in the analysis of Ca-ATPase in the sarcoplasmic reticulum of rabbit skeletal muscles in hypercholesteremia]
Hyperglycemia
Cardiac contractile dysfunction during acute hyperglycemia due to impairment of SERCA by polyol pathway-mediated oxidative stress.
Hyperglycemia
Corneal hydration control in normal and alloxan-induced diabetic rabbits.
Hyperglycemia
Critical reduction in beta-cell mass results in two distinct outcomes over time. Adaptation with impaired glucose tolerance or decompensated diabetes.
Hyperglycemia
Effects of Hyperglycemia on Vascular Smooth Muscle Ca(2+) Signaling.
Hyperglycemia
Influence of hyperglycemia on Ca2+-Mg2+ -ATPase of red blood cells from diabetic patients.
Hyperglycemia
Inhibition of diabetic-cataract by vitamin K1 involves modulation of hyperglycemia-induced alterations to lens calcium homeostasis.
Hyperglycemia
Pharmacological inhibition of soluble epoxide hydrolase provides cardioprotection in hyperglycemic rats.
Hyperglycemia
Protective effects of a calcium channel blocker on apoptosis in thymus of neonatal STZ-diabetic rats.
Hyperglycemia
Sarcoplasmic reticulum Ca(2+) ATPase pump is a major regulator of glucose transport in the healthy and diabetic heart.
Hyperglycemia
The effect of in vivo glucose administration on human erythrocyte Ca2+-ATPase activity and on enzyme responsiveness in vitro to thyroid hormone and calmodulin.
Hyperhomocysteinemia
Response of secretory pathways Ca(2+) ATPase gene expression to hyperhomocysteinemia and/or ischemic preconditioning in rat cerebral cortex and hippocampus.
Hyperhomocysteinemia
Taurine protected myocardial mitochondria injury induced by hyperhomocysteinemia in rats.
Hyperkalemia
Works on heart, how about brain? Effect of hyperkalemia on focal cerebral ischemia/reperfusion injury in rats.
Hyperlipidemias
Blocking the urotensin II receptor pathway ameliorates the metabolic syndrome and improves cardiac function in obese mice.
Hyperlipidemias
Regulation of rabbit erythrocyte Ca(2+)-pump sensitivity to calmodulin in experimental hyperlipidemia.
Hyperparathyroidism, Secondary
Depression of calcium pump activity in renal cortex of vitamin D-deficient rats with secondary hyperparathyroidism.
Hypersensitivity
A plant Ca2+ pump, ACA2, relieves salt hypersensitivity in yeast. Modulation of cytosolic calcium signature and activation of adaptive Na+ homeostasis.
Hypersensitivity
Endogenously generated reactive oxygen species reduce PMCA activity in platelets from patients with non-insulin-dependent diabetes mellitus.
Hypersensitivity
Hypersensitivity to calcium associated with an increased sarcolemmal Ca2+-ATPase activity in diabetic rat heart.
Hypersensitivity
In vitro model of ischemic heart failure using human induced pluripotent stem cell-derived cardiomyocytes.
Hypertension
(Na+,K+)-activated adenosinetriphosphatase and hypertension in DAHL salt- sensitive and -resistant rats.
Hypertension
Alteration of cellular calcium metabolism as primary cause of hypertension.
Hypertension
Ca2+ buffering function of the sarcoplasmic reticulum is increased in the carotid artery from spontaneously hypertensive rats.
Hypertension
Calcium and abnormal reactivity of vascular smooth muscle in hypertension.
Hypertension
Calcium handling and sarcoplasmic-reticular protein functions during heart-failure transition in ventricular myocardium from rats with hypertension.
Hypertension
Cellular Ca2+ ATPase activity in diabetes mellitus.
Hypertension
Combined SSCP and heteroduplex analysis of the human plasma membrane Ca(2+)-ATPase isoform 1 in patients with essential hypertension.
Hypertension
E3 Ubiquitin ligase NEDD4 family?regulatory network in cardiovascular disease.
Hypertension
Effects of sarcoplasmic reticulum calcium pump inhibitors on vascular smooth muscle.
Hypertension
Enhancement of intrarenal plasma membrane calcium pump isoform 1 expression in chronic angiotensin II-infused mice.
Hypertension
Expression of sarcoplasmic reticulum Ca2+ -ATPase mRNA in the hypertrophied heart of young spontaneously hypertensive rats.
Hypertension
Functional characterization of alternatively spliced human SERCA3 transcripts.
Hypertension
Genotypes of sarco(endo)plasmic reticulum Ca(2+)-dependent ATPase II gene in substrains of spontaneously hypertensive rats.
Hypertension
Impaired calcium metabolism associated with hypertension in Zucker obese rats.
Hypertension
Inactivation of Cys674 in SERCA2 increases BP by inducing endoplasmic reticulum stress and soluble epoxide hydrolase.
Hypertension
Increased expression of plasma membrane Ca(2+)ATPase 4b in platelets from hypertensives: A new sign of abnormal thrombopoiesis?
Hypertension
Inhibition of sarco(endo)plasmic reticulum Ca2+-ATPase differentially regulates contractile function in cardiac myocytes from normotensive and spontaneously hypertensive rats: role of Ca2+ regulatory proteins.
Hypertension
Intra-tracheal gene delivery of aerosolized SERCA2a to the lung suppresses ventricular arrhythmias in a model of pulmonary arterial hypertension.
Hypertension
Kinetic study of the Ca2+ pump in erythrocytes from essential hypertensive patients.
Hypertension
Localisation of calcium-activated adenosine-triphosphatase (Ca2+-ATPase) in intracerebral arterioles in acute hypertension.
Hypertension
Membrane transport and disease.
Hypertension
Neuroendocrine humoral and vascular components in the pressor pathway for brain angiotensin II: a new axis in long term blood pressure control.
Hypertension
NO donors-relaxation is impaired in aorta from hypertensive rats due to a reduced involvement of K(+) channels and sarcoplasmic reticulum Ca(2+)-ATPase.
Hypertension
Plasma membrane calcium ATPases (PMCAs) as potential targets for the treatment of essential hypertension.
Hypertension
Platelet Ca(2+)ATPases : a plural, species-specific, and multiple hypertension-regulated expression system.
Hypertension
Preeclampsia and calcium-ATPase activity of plasma membranes from human myometrium and placental trophoblast.
Hypertension
Reduced expression of PMCA1 is associated with increased blood pressure with age which is preceded by remodelling of resistance arteries.
Hypertension
Role of cellular calcium metabolism in abnormal glucose metabolism and diabetic hypertension.
Hypertension
Sarcoplasmic reticulum Ca2+ uptake is not decreased in aorta from deoxycorticosterone acetate hypertensive rats: functional assessment with cyclopiazonic acid.
Hypertension
Serum from patients with hypertension promotes endothelial dysfunction to induce trophoblast invasion through the miR?27b?3p/ATPase plasma membrane Ca2+ transporting 1 axis.
Hypertension
Thapsigargin-insensitive calcium pools in vascular smooth muscle cells.
Hypertension
[Calcium pump changes in patients with essential arterial hypertension]
Hypertension
[INCREASE OF SERUM ADENOSINETRIPHOSPHATASE IN ARTERIAL HYPERTENSION.]
Hypertension, Pulmonary
E3 Ubiquitin ligase NEDD4 family?regulatory network in cardiovascular disease.
Hypertension, Pulmonary
Intratracheal Gene Delivery of SERCA2a Ameliorates Chronic Post-Capillary Pulmonary Hypertension: A Large Animal Model.
Hypertension, Renal
Ca2+ ATPase activity in essential and renal hypertension.
Hypertension, Renovascular
Effects of systolic overload and swim training on cardiac mechanics and biochemistry in rats.
Hypertension, Renovascular
Senescent heart compared with pressure overload-induced hypertrophy.
Hyperthyroidism
Cardiac microRNA-133 is down-regulated in thyroid hormone-mediated cardiac hypertrophy partially via Type 1 Angiotensin II receptor.
Hyperthyroidism
Cardiac sarcoplasmic reticulum Ca2+-ATPase: heat production and phospholamban alterations promoted by cold exposure and thyroid hormone.
Hyperthyroidism
Cellular mechanisms of reduced sarcoplasmic reticulum Ca2+ content in L-thyroxininduced rat ventricular hypertrophy.
Hyperthyroidism
Compensatory adaptation of the heart to chronic rate overload: increase in calcium transport ATPase activity of myocardial sarcoplasmic reticulum.
Hyperthyroidism
Coordinate downregulation of CaM kinase II and phospholamban accompanies contractile phenotype transition in the hyperthyroid rabbit soleus.
Hyperthyroidism
Coordinated fast-to-slow transitions of myosin and SERCA isoforms in chronically stimulated muscles of euthyroid and hyperthyroid rabbits.
Hyperthyroidism
Different time course of changes in sarcoplasmic reticulum and myosin isoforms in rat soleus muscle at early stage of hyperthyroidism.
Hyperthyroidism
Differential effects of thyroid hormone on the expression of sarcoplasmic reticulum Ca(2+)-ATPase isoforms in rat skeletal muscle fibers.
Hyperthyroidism
Differential influences of carnitine palmitoyltransferase-1 inhibition and hyperthyroidism on cardiac growth and sarcoplasmic reticulum phosphorylation.
Hyperthyroidism
Effects of hyperthyroidism and hypothyroidism on human red blood cell Ca2+-ATPase activity.
Hyperthyroidism
Effects of thyroid hormones on contractility and cation transport in skeletal muscle.
Hyperthyroidism
Hyperthyroid dog left ventricle has the same oxygen consumption versus pressure-volume area (PVA) relation as euthyroid dog.
Hyperthyroidism
Hyperthyroidism and cation pumps in human skeletal muscle.
Hyperthyroidism
Hyperthyroidism causes mechanical insufficiency of myocardium with possibly increased SR Ca2+-ATPase activity.
Hyperthyroidism
Hyperthyroidism increases the uncoupled ATPase activity and heat production by the sarcoplasmic reticulum Ca2+-ATPase.
Hyperthyroidism
Increased acylphosphatase levels in erythrocytes from hyperthyroid patients.
Hyperthyroidism
Myosin and SERCA isoform expression in denervated slow-twitch muscle of euthyroid and hyperthyroid rabbits.
Hyperthyroidism
Possible activation of NRF2 by Vitamin E/Curcumin against altered thyroid hormone induced oxidative stress via NF?B/AKT/mTOR/KEAP1 signalling in rat heart.
Hyperthyroidism
Reconstitution of heavy chain and light chain 1 in cardiac subfragment-1 from hyperthyroid and euthyroid rabbit hearts.
Hyperthyroidism
Role of sarco/endoplasmic reticulum Ca(2+)-ATPase in thermogenesis.
Hyperthyroidism
Special sensitization pattern in adenosine-induced myocardial responses after thyroxine-treatment.
Hyperthyroidism
The thermogenic function of the sarcoplasmic reticulum Ca2+-ATPase of normal and hyperthyroid rabbit.
Hyperthyroidism
Thyroid control of sarcolemmal Na+/Ca2+ exchanger and SR Ca2+-ATPase in developing rat heart.
Hyperthyroidism
Thyroid hormone differentially affects mRNA levels of Ca-ATPase isozymes of sarcoplasmic reticulum in fast and slow skeletal muscle.
Hyperthyroidism
Thyroid hormone downregulates the expression and function of sarcoplasmic reticulum-associated CaM kinase II in the rabbit heart.
Hyperthyroidism
Thyroid hormone enhances Ca2+ pumping activity of the cardiac sarcoplasmic reticulum by increasing Ca2+ ATPase and decreasing phospholamban expression.
Hyperthyroidism
Thyroid hormone markedly increases the mRNA coding for sarcoplasmic reticulum Ca2+-ATPase in the rat heart.
Hyperthyroidism
Thyroid hormone-induced alterations in phospholamban-deficient mouse hearts.
Hyperthyroidism
Thyroid hormones differentially regulate the distribution of rabbit skeletal muscle Ca(2+)-ATPase (SERCA) isoforms in light and heavy sarcoplasmic reticulum.
Hyperthyroidism
Type 2 iodothyronin deiodinase transgene expression in the mouse heart causes cardiac-specific thyrotoxicosis.
Hyperthyroidism
[Increased activity of sarcoplasmic reticulum Ca(2+)-ATPase in soleus of hyperthyroid rat accelerates fatigue during intermittent tetanic contraction.]
Hypertrophy, Left Ventricular
Blockade of the renin-angiotensin system in cardiac pressure-overload hypertrophy in rats.
Hypertrophy, Left Ventricular
Calcium homeostasis behavior and cardiac function on left ventricular remodeling by pressure overload.
Hypertrophy, Left Ventricular
Downregulation of sarcoplasmic reticulum Ca(2+)-ATPase during progression of left ventricular hypertrophy.
Hypertrophy, Left Ventricular
PYK2 regulates SERCA2 gene expression in neonatal rat ventricular myocytes.
Hypertrophy, Left Ventricular
The sarco(endo)plasmic reticulum Ca(2+)-ATPase gene is regulated at the transcriptional level during compensated left ventricular hypertrophy in the rat.
Hypertrophy, Left Ventricular
[Effect of astragalus on calcium accumulation and SERCA2a gene expression in myocardial tissues in rats with pressure overload-induced left ventricular hypertrophy]
Hypertrophy, Left Ventricular
[Role of the M235T (c.704c>T) polymorphism of angiotensynogen gene as well as A724A (c.2171G>A) polymorphism of SERCA2a gene in ethiopathogenesis of left ventricular hypertrophy in essential hypertension]
Hypertrophy, Right Ventricular
Restoration of calcium handling properties of adult cardiac myocytes from hypertrophied hearts.
Hypocalcemia
Alkaline phosphatases in endochondral ossification of rats low in calcium and vitamin D deficient.
Hypocalcemia
Chronic hypocalcemia of vitamin D deficiency leads to lower intracellular calcium concentrations in rat hepatocytes.
Hypocalcemia
The sarcolemmal Ca2+-ATPase of the ischemic-reperfused myocardium: protective effect of hypocalcemia on calmodulin-stimulated activity.
Hypokinesia
[Energy-dependent transport of Ca2+ and lipid peroxidation in the sarcoplasmic reticular membranes of rats during hypokinesia]
Hypophosphatemia
[Disordered phosphorus metabolism and its correction in the acute period of severe craniocerebral trauma]
Hypotension
[Treatment of heart failure patients with inotropic drugs: beyond traditional agents].
Hypothyroidism
Cardiac sarcoplasmic reticulum calcium transport activity of thyroidectomized rats: the role of endogenous myocardial acylcarnitines and calcium pump protein.
Hypothyroidism
Decreased cardiac SERCA2 expression, SR Ca uptake, and contractile function in hypothyroidism are attenuated in SERCA2 overexpressing transgenic rats.
Hypothyroidism
Effects of experimentally-induced maternal hypothyroidism on crucial offspring rat brain enzyme activities.
Hypothyroidism
Effects of hyperthyroidism and hypothyroidism on human red blood cell Ca2+-ATPase activity.
Hypothyroidism
Influence of hypothyroidism on testicular mitochondrial oxidative stress by activating the p38 mitogen-activated protein kinase and c-Jun NH2-terminal kinase signaling pathways in rats.
Hypothyroidism
Low thyroid function leads to cardiac atrophy with chamber dilatation, impaired myocardial blood flow, loss of arterioles, and severe systolic dysfunction.
Hypothyroidism
Overexpression myocardial inducible nitric oxide synthase exacerbates cardiac dysfunction and beta-adrenergic desensitization in experimental hypothyroidism.
Hypothyroidism
Overexpression of sarcoplasmic reticulum Ca(2+)-ATPase improves cardiac contractile function in hypothyroid mice.
Hypothyroidism
SERCA2 Haploinsufficiency in a Mouse Model of Darier Disease Causes a Selective Predisposition to Heart Failure.
Hypothyroidism
The Change of Left Ventricular Function in Rats with Subclinical Hypothyroid and the Effects of Thyroxine Replacement.
Hypothyroidism
Thyroid control of sarcolemmal Na+/Ca2+ exchanger and SR Ca2+-ATPase in developing rat heart.
Hypothyroidism
Thyroid hormone differentially affects mRNA levels of Ca-ATPase isozymes of sarcoplasmic reticulum in fast and slow skeletal muscle.
Hypothyroidism
Thyroid hormone influences muscle mechanics in carp (Cyprinus carpio) independently from SERCA activity.
Hypothyroidism
Thyroid hormone regulates muscle function during cold acclimation in zebrafish (Danio rerio).
Hypothyroidism
Thyroid hormone regulates Na(+)-Ca2+ exchanger expression during postnatal maturation and in adult rabbit ventricular myocardium.
Hypothyroidism
Thyroid hormone response of slow and fast sarcoplasmic reticulum Ca2+ ATPase mRNA in striated muscle.
Hypothyroidism
Thyroid hormone-induced alterations in phospholamban-deficient mouse hearts.
Hypothyroidism
Thyroid hormones differentially regulate the distribution of rabbit skeletal muscle Ca(2+)-ATPase (SERCA) isoforms in light and heavy sarcoplasmic reticulum.
Hypothyroidism
Ventricular myosin from young and adult animals with respect to the thyroid state.
Hypoxia, Brain
Nuclear mechanisms of hypoxic cerebral injury in the newborn.
Infections
Abnormalities in heart membranes and myofibrils during bacterial infective cardiomyopathy in the rabbit.
Infections
Adenoviral SERCA1 overexpression triggers an apoptotic response in cultured neonatal but not in adult rat cardiomyocytes.
Infections
Artemether resistance in vitro is linked to mutations in PfATP6 that also interact with mutations in PfMDR1 in travellers returning with Plasmodium falciparum infections.
Infections
Cardiac protective effect of astragalus on viral myocarditis mice: comparison with perindopril.
Infections
Cell-specific expression of SERCA, the exogenous Ca2+ transport ATPase, in cardiac myocytes.
Infections
Chronic treatment with insulin-like growth factor I enhances myocyte contraction by upregulation of Akt-SERCA2a signaling pathway.
Infections
Differential expression of the plasma membrane Mg2+ ATPase and Ca2+ ATPase activity during adhesion and interiorization of Leishmania amazonensis in fibroblasts in vitro.
Infections
Effects of mutant and antisense RNA of phospholamban on SR Ca(2+)-ATPase activity and cardiac myocyte contractility.
Infections
Effects of peroxynitrite on sarco/endoplasmic reticulum Ca2+ pump isoforms SERCA2b and SERCA3a.
Infections
Evaluation of artemether-lumefantrine efficacy in the treatment of uncomplicated malaria and its association with pfmdr1, pfatpase6 and K13-propeller polymorphisms in Luanda, Angola.
Infections
Excessive sarcoplasmic/endoplasmic reticulum Ca2+-ATPase expression causes increased sarcoplasmic reticulum Ca2+ uptake but decreases myocyte shortening.
Infections
Improved expression and characterization of Ca2+-ATPase and phospholamban in High-Five cells.
Infections
Influences of increased expression of the Ca2+ ATPase of the sarcoplasmic reticulum by a transgenic approach on cardiac contractility.
Infections
Inhibitor of Sarco/Endoplasmic Reticulum Calcium-ATPase Impairs Multiple Steps of Paramyxovirus Replication.
Infections
Intracellular disassembly of infectious rotavirus particles by depletion of Ca2+ sequestered in the endoplasmic reticulum at the end of virus cycle.
Infections
Localization of intracellular Ca2+ stores in HeLa cells during infection with Chlamydia trachomatis.
Infections
Membrane transport and disease.
Infections
Mitochondrial ATP-ASE as a measure of uncoupling of rat muscle mitochondria in experimental infection with Trichinella spiralis and Trichinella pseudospiralis.
Infections
Modulation of B-cell endoplasmic reticulum calcium homeostasis by Epstein-Barr virus latent membrane protein-1.
Infections
Overexpression of Na+/Ca2+ exchanger alters contractility and SR Ca2+ content in adult rat myocytes.
Infections
Overexpression of SERCA2a accelerates repolarisation in rabbit ventricular myocytes.
Infections
Physiological effects of adenoviral gene transfer of sarcoplasmic reticulum calcium ATPase in isolated rat myocytes.
Infections
PYK2 regulates SERCA2 gene expression in neonatal rat ventricular myocytes.
Infections
Regulation and rate limiting mechanisms of Ca2+ ATPase (SERCA2) expression in cardiac myocytes.
Infections
Restoration of diastolic function in senescent rat hearts through adenoviral gene transfer of sarcoplasmic reticulum Ca(2+)-ATPase.
Infections
SERCA2a gene transfer prevents intimal proliferation in an organ culture of human internal mammary artery.
Infections
Tacaribe virus infection may induce inhibition of the activity of the host cell Ca2+ and Na+/K+ pumps.
Infections
The effect of Mycoplasma pneumoniae infection on human erythrocytes: changes in osmotic fragility, lipid composition, sialic acid content, Ca2+-ATPase activities, and ATP concentration.
Infections
The Golgi calcium ATPase pump plays an essential role in AAV trafficking and transduction.
Infections
The influence of porcine epidemic diarrhea virus on pig small intestine mucosal epithelial cell function.
Infections
The Na+/Ca2+ exchanger/SR Ca2+ ATPase transport capacity regulates the contractility of normal and hypertrophied feline ventricular myocytes.
Infections
The plasma membrane calcium ATPase 4 does not influence parasite levels but partially promotes experimental cerebral malaria during murine blood stage malaria.
Infections
The t-SNARE protein FgPep12, associated with FgVam7, is essential for ascospore discharge and plant infection by trafficking Ca2+ ATPase FgNeo1 between Golgi and endosome/vacuole in Fusarium graminearum.
Infections
Total Flavonoids of Astragalus Plays a Cardioprotective Role in Viral Myocarditis.
Infections
Viral myocarditis involves the generation of autoreactive T cells with multiple antigen specificities that localize in lymphoid and non-lymphoid organs in the mouse model of CVB3 infection.
Infections
[Effects of lentivirus-mediated heat shock protein 70 gene on endoplasmic reticulum calcium homeostasis and calcium channels of PC12 cells induced by ischemia and hypoxia].
Infections
[Expression of sarco/endoplasmic reticulum Ca(2+)-ATPase from Bombyx mori by baculovirus expression system].
Infertility
A New Baltic Population-Specific Human Genetic Marker in the PMCA4 Gene.
Infertility
Abnormal deficiency of both Mg2+ and Ca2+-dependent adenosine triphosphatase and secretory granules and vesicles in human seminal plasma.
Infertility
Evaluation of plasma membrane calcium/calmodulin-dependent ATPase isoform 4 as a potential target for fertility control.
Infertility
Optimisation and validation of a high throughput screening compatible assay to identify inhibitors of the plasma membrane calcium ATPase pump - a novel therapeutic target for contraception and malaria.
Infertility
Plasma membrane Ca(2+)-ATPase: from a housekeeping function to a versatile signaling role.
Infertility
Plasma membrane Ca2+-ATPase 4 in murine epididymis: secretion of splice variants in the luminal fluid and a role in sperm maturation.
Infertility
Plasma membrane Ca2+-ATPase 4: interaction with constitutive nitric oxide synthases in human sperm and prostasomes which carry Ca2+/CaM-dependent serine kinase.
Infertility
Plasma membrane calcium ATPase 4 (PMCA4) co-ordinates calcium and nitric oxide signaling in regulating murine sperm functional activity.
Infertility, Male
Expression and secretion of plasma membrane Ca2+-ATPase 4a (PMCA4a) during murine estrus: association with oviductal exosomes and uptake in sperm.
Infertility, Male
Oviductal extracellular vesicles (oviductosomes, OVS) are conserved in humans: murine OVS play a pivotal role in sperm capacitation and fertility.
Infertility, Male
Phenotypes of SERCA and PMCA knockout mice.
Infertility, Male
Plasma membrane Ca2+-ATPase 4: interaction with constitutive nitric oxide synthases in human sperm and prostasomes which carry Ca2+/CaM-dependent serine kinase.
Influenza, Human
Sarco/Endoplasmic Reticulum Ca2+ Transporting ATPase (SERCA) Modulates Autophagic, Inflammatory, and Mitochondrial Responses during Influenza A Virus Infection in Human Lung Cells.
Influenza, Human
Thapsigargin at Non-Cytotoxic Levels Induces a Potent Host Antiviral Response that Blocks Influenza A Virus Replication.
Influenza, Human
Thapsigargin Is a Broad-Spectrum Inhibitor of Major Human Respiratory Viruses: Coronavirus, Respiratory Syncytial Virus and Influenza A Virus.
Insulin Resistance
A natural compound jaceosidin ameliorates endoplasmic reticulum stress and insulin resistance via upregulation of SERCA2b.
Insulin Resistance
DEL-1 ameliorates high-fat diet-induced insulin resistance in mouse skeletal muscle through SIRT1/SERCA2-mediated ER stress suppression.
Insulin Resistance
Hugan Qingzhi medication ameliorates free fatty acid-induced L02 hepatocyte endoplasmic reticulum stress by regulating the activation of PKC-?.
Insulin Resistance
Inverse correlation between levels of glycated haemoglobin and expression levels of SERCA protein in Mexican patients with type 2 diabetes mellitus.
Insulin Resistance
MicroRNA-30b Regulates Insulin Sensitivity by Targeting SERCA2b in Non-alcoholic Fatty Liver Disease.
Insulin Resistance
Palmitic acid but not palmitoleic acid induces insulin resistance in a human endothelial cell line by decreasing SERCA pump expression.
Insulin Resistance
Prolonged preoperative fasting induces postoperative insulin resistance by ER-stress mediated Glut4 down-regulation in skeletal muscles.
Insulin Resistance
Small Molecular Allosteric Activator of the Sarco/Endoplasmic Reticulum Ca2+-ATPase (SERCA) Attenuates Diabetes and Metabolic Disorders.
Insulinoma
Apoptosis of insulin-secreting cells induced by endoplasmic reticulum stress is amplified by overexpression of group VIA calcium-independent phospholipase A2 (iPLA2 beta) and suppressed by inhibition of iPLA2 beta.
Insulinoma
HDL inhibits endoplasmic reticulum stress-induced apoptosis of pancreatic ?-cells in vitro by activation of Smoothened.
Iron Overload
Oxidative damage to sarcoplasmic reticulum Ca2+-ATPase AT submicromolar iron concentrations: evidence for metal-catalyzed oxidation.
Isaacs Syndrome
A defective SERCA1 protein is responsible for congenital pseudomyotonia in Chianina cattle.
Isaacs Syndrome
Fast-twitch skeletal muscle fiber adaptation to SERCA1 deficiency in a Dutch Improved Red and White calf pseudomyotonia case.
Isaacs Syndrome
Identification of a missense mutation in the bovine ATP2A1 gene in congenital pseudomyotonia of Chianina cattle: an animal model of human Brody disease.
Isaacs Syndrome
Inhibition of ubiquitin proteasome system rescues the defective sarco(endo)plasmic reticulum Ca2+-ATPase (SERCA1) protein causing Chianina cattle pseudomyotonia.
Ischemic Contracture
[Role of disorders of calcium homeostasis in the development of ischemic contracture of the heart]
Ischemic Stroke
Olfactory Mucosa Mesenchymal Stem Cells Alleviate Cerebral Ischemia/Reperfusion Injury Via Golgi Apparatus Secretory Pathway Ca2+ -ATPase Isoform1.
Kidney Diseases
Endoplasmic Reticulum Calcium Homeostasis in Kidney Disease: Pathogenesis and Therapeutic Targets.
Kidney Diseases
[Behavior of adenosinetriphosphatase activity of the kidneys in some experimental and human kidney diseases.]
Kidney Failure, Chronic
A circulating inhibitor of the RBC membrane calcium pump in chronic renal failure.
Kidney Failure, Chronic
Biochemical changes associated with the osmotic fragility of young and mature erythrocytes caused by parathyroid hormone in relation to the uremic syndrome.
Kidney Failure, Chronic
Characterization of dimethylguanosine, phenylethylamine, and phenylacetic acid as inhibitors of Ca2+ ATPase in end-stage renal failure.
Kidney Failure, Chronic
Characterization of p-hydroxy-hippuric acid as an inhibitor of Ca2+-ATPase in end-stage renal failure.
Kidney Failure, Chronic
Effect of chronic renal failure on Ca2+ ATPase of brain synaptosomes.
Kidney Failure, Chronic
Effect of end-stage renal disease on responsiveness to calmodulin and thyroid hormone of calcium-ATPase in human red blood cells.
Kidney Failure, Chronic
Effect of parathyroid hormone on the fragility and enzyme activities of red blood cells from young and mature rabbits.
Kidney Failure, Chronic
Effects of chronic renal failure with and without excess parathyroid hormone on calmodulin content of pancreatic islets and on the response of their Ca2+ ATPase to calmodulin.
Kidney Failure, Chronic
[Calpain-calpastatin system in erythrocytes of children with chronc renal failure]
Kidney Failure, Chronic
[The immune-enzyme technique of detection of Ca2+ ATPase of sarcoplasmic reticulum--a new biologic marker of acute cardiac infarction].
Kwashiorkor
Erythrocyte membrane (Ca2+ + Mg2+)-ATPase in human protein-energy malnutrition.
Leishmaniasis
Immunomodulator mediated changes in plasma membrane calcium ATPase in controlling visceral leishmaniasis.
Leishmaniasis
Regulation of PKC mediated signaling by calcium during visceral leishmaniasis.
Leishmaniasis, Visceral
Immunomodulator mediated changes in plasma membrane calcium ATPase in controlling visceral leishmaniasis.
Leukemia
Association of enzymes: adenosinetriphosphatase and alkaline phosphatase with the virions of murine leukemias.
Leukemia
Ca2+-ATPase inhibitors and PKC activation synergistically stimulate TNF-alpha production in RBL-2H3 cells.
Leukemia
Complementary Genomic Screens Identify SERCA as a Therapeutic Target in NOTCH1 Mutated Cancer.
Leukemia
Distribution of inositol 1,4,5-trisphosphate receptor isoforms, SERCA isoforms and Ca2+ binding proteins in RBL-2H3 rat basophilic leukemia cells.
Leukemia
Endoplasmic Reticulum Calcium Pumps and Tumor Cell Differentiation.
Leukemia
Induction of endoplasmic reticulum calcium pump expression during early leukemic B cell differentiation.
Leukemia
Leukemia Inhibitory Factor and Interleukin-6 downregulate sarcoplasmic reticulum Ca2+ ATPase (SERCA2) in cardiac myocytes.
Leukemia
Lineage-specific modulation of calcium pump expression during myeloid differentiation.
Leukemia
[Changes in Ca2+-ATPase activity in blast cells of acute leukemia patients]
Leukemia
[Expression of SERCA pumps during cell differentiation and tumorigenesis: application to colonic carcinogenesis]
Leukemia, Erythroblastic, Acute
Early transient suppression of c-myb mRNA levels and induction of differentiation in Friend erythroleukemia cells by the [Ca2+]i-increasing agents cyclopiazonic acid and thapsigargin.
Leukemia, Erythroblastic, Acute
Role of the glycoprotein IIb-IIIa complex in plasma membrane Ca2+ transport: a comparison of results obtained with platelets and human erythroleukemia cells.
Leukemia, Lymphocytic, Chronic, B-Cell
Blockade of Oncogenic NOTCH1 with the SERCA Inhibitor CAD204520 in T Cell Acute Lymphoblastic Leukemia.
Leukemia, Myeloid, Acute
A Novel SERCA Inhibitor Demonstrates Synergy with Classic SERCA Inhibitors and Targets Multidrug-Resistant AML.
Leukemia, Myeloid, Acute
Tipifarnib-induced apoptosis in acute myeloid leukemia and multiple myeloma cells is dependent on Ca2+ influx through plasma membrane Ca2+ channels.
Leukemia, Promyelocytic, Acute
Lineage-specific modulation of calcium pump expression during myeloid differentiation.
Liposarcoma
High expression of sarcoplasmic/endoplasmic reticulum Ca(2+)-ATPase 2b blocks cell differentiation in human liposarcoma cells.
Liposarcoma
Targeting Sarcoplasmic/Endoplasmic Reticulum Ca2+-ATPase 2 by Curcumin Induces ER Stress-Associated Apoptosis for Treating Human Liposarcoma.
Liver Diseases
Correction to: Matrine attenuates endoplasmic reticulum stress and mitochondrion dysfunction in nonalcoholic fatty liver disease by regulating SERCA pathway.
Liver Diseases
Matrine attenuates endoplasmic reticulum stress and mitochondrion dysfunction in nonalcoholic fatty liver disease by regulating SERCA pathway.
Liver Diseases
MicroRNA-30b Regulates Insulin Sensitivity by Targeting SERCA2b in Non-alcoholic Fatty Liver Disease.
Liver Neoplasms, Experimental
Deoxyribonucleic acid dependent adenosinetriphosphatases from the Novikoff hepatoma. Characterization of a homogeneous adenosinetriphosphatase that stimulates DNA polymerase beta.
Lung Diseases
Activator-associated Ca2+-ATPase in erythrocyte membranes from cystic fibrosis patients.
Lung Neoplasms
Analysis of chemoresistance in lung cancer with a simple microfluidic device.
Lung Neoplasms
Chemotherapy resistance research of lung cancer based on micro-fluidic chip system with flow medium.
Lung Neoplasms
Effect of long non-coding RNA long stress-induced noncoding transcript 5 on erlotinib resistance to lung cancer cells and the underlying mechanisms.
Lung Neoplasms
GRP78 upregulation-induced increase in cisplatin sensitivity of SPCA1 lung cancer cells.
Lung Neoplasms
Histone deacetylase inhibitors promote the expression of ATP2A3 gene in breast cancer cell lines.
Lung Neoplasms
Loss of RhoA expression prevents proliferation and metastasis of SPCA1 lung cancer cells in vitro.
Lung Neoplasms
Modulation of endoplasmic reticulum calcium pump expression during lung cancer cell differentiation.
Lung Neoplasms
RhoA inhibits apoptosis and increases proliferation of cultured SPCA1 lung cancer cells.
Lung Neoplasms
Tunicamycin enhances the suppressive effects of cisplatin on lung cancer growth through PTX3 glycosylation via AKT/NF-?B signaling pathway.
Lung Neoplasms
Zebrafish xenograft model of human lung cancer for studying the function of LINC00152 in cell proliferation and invasion.
Lung Neoplasms
[Ca2+, Mg2+-ATPase activity of the erythrocyte membrane in patients with lung cancer]
Lung Neoplasms
[Effect of adenomatous polyposis coli(APC) promoter methylation on gene transcription in lung cancer cell lines]
Lupus Erythematosus, Discoid
Incidental Focal Acantholytic Dyskeratosis in a Patient with Discoid Lupus Erythematosus: A Possible Role for SPCA1 in the Pathogenesis of the Disease.
Lymphatic Metastasis
Aberrant SERCA3 expression during the colorectal adenoma-adenocarcinoma sequence.
Lymphatic Metastasis
Aberrant SERCA3 expression is closely linked to pathogenesis, invasion, metastasis, and prognosis of gastric carcinomas.
Lymphatic Metastasis
Plasma membrane calcium ATPase expression in human colon multistep carcinogenesis.
Lymphatic Metastasis
Sarco/endoplasmic reticulum calcium-ATPase 2 expression as a tumor marker in colorectal cancer.
Lymphatic Metastasis
SBF-1 exerts strong anticervical cancer effect through inducing endoplasmic reticulum stress-associated cell death via targeting sarco/endoplasmic reticulum Ca(2+)-ATPase 2.
Lymphoma
Maintenance of calcium homeostasis in the endoplasmic reticulum by Bcl-2.
Lymphoma
Paradoxical effect of testosterone supplementation therapy on cardiac ischemia/reperfusion injury in aged rats.
Lymphoma, B-Cell
Paradoxical effect of testosterone supplementation therapy on cardiac ischemia/reperfusion injury in aged rats.
Lymphopenia
Sarco/endoplasmic reticulum Ca2+-ATPase (SERCA) activity is required for V(D)J recombination.
Magnesium Deficiency
Thalasselis' syndrome and other theories on keratoconus.
Malaria
Artemisinin dimer anticancer activity correlates with heme-catalyzed reactive oxygen species generation and endoplasmic reticulum stress induction.
Malaria
Assessment and Characterization of Ca2+ - ATPase expression in selected isolates and clones of Plasmodium Falciparum.
Malaria
Calcium-dependent Protein Kinases in Malaria Parasite Development and Infection.
Malaria
Considerations on the mechanism of action of artemisinin antimalarials: part 1--the 'carbon radical' and 'heme' hypotheses.
Malaria
Detecting adenosine triphosphatase 6 (pfATP6) point mutations that may be associated with Plasmodium falciparum resistance to artemisinin: prevalence at baseline, before policy change in Uganda.
Malaria
Effect of chloroquine phosphate and toxic concentrations of lead acetate on Ca2+-ATPase activity in isolates and clones of Plasmodium Falciparum.
Malaria
Fragment Molecular Orbital Study of the Interaction between Sarco/Endoplasmic Reticulum Ca2+-ATPase and its Inhibitor Thapsigargin toward Anti-Malarial Development.
Malaria
Genome-wide association study indicates two novel resistance loci for severe malaria.
Malaria
Mechanism of artemisinin resistance for malaria PfATP6 L263 mutations and discovering potential antimalarials: An integrated computational approach.
Malaria
Modulation of the Human Erythroid Plasma Membrane Calcium Pump (PMCA4b) Expression by Polymorphic Genetic Variants.
Malaria
Molecular epidemiology of malaria in Cameroon. XXVIII. In vitro activity of dihydroartemisinin against clinical isolates of Plasmodium falciparum and sequence analysis of the P. falciparum ATPase 6 gene.
Malaria
Molecular markers of anti-malarial drug resistance in Central, West and East African children with severe malaria.
Malaria
Optimisation and validation of a high throughput screening compatible assay to identify inhibitors of the plasma membrane calcium ATPase pump - a novel therapeutic target for contraception and malaria.
Malaria
Plasmodium falciparum: Genetic diversity and complexity of infections in an isolated village in western Thailand.
Malaria
Questions over high frequency of mutant PfATP6 haplotypes in traveller isolates.
Malaria
Successful application of virtual screening and molecular dynamics simulations against antimalarial molecular targets.
Malaria
The plasma membrane calcium ATPase 4 does not influence parasite levels but partially promotes experimental cerebral malaria during murine blood stage malaria.
Malaria, Cerebral
The plasma membrane calcium ATPase 4 does not influence parasite levels but partially promotes experimental cerebral malaria during murine blood stage malaria.
Malnutrition
Effect of exercise during rehabilitation on swimming performance, metabolism and function of muscle in rats.
Malnutrition
Effects of thyroid hormones on contractility and cation transport in skeletal muscle.
Malnutrition
The Ca2+-transporting activity of rat liver microsomes in response to protein undernutrition: implications for liver tumor promotion.
Mania
RBC membrane adenosine triphosphatase activities in patients with major affective disorders.
Mastocytoma
Synthesis and activation of mitotic Ca2+-adenosinetriphosphatase during the cell cycle of mouse mastocytoma cells.
Measles
Diverse Viruses Require the Calcium Transporter SPCA1 for Maturation and Spread.
Melanoma
Histone Deacetylase Inhibitor Treatment Increases the Expression of the Plasma Membrane Ca(2+) Pump PMCA4b and Inhibits the Migration of Melanoma Cells Independent of ERK.
Melanoma
P38 MAPK Promotes Migration and Metastatic Activity of BRAF Mutant Melanoma Cells by Inducing Degradation of PMCA4b.
Melanoma
Properties of adenosinetriphosphatase in sub-cellular particles of mouse melanoma.
Melanoma
Synthetic peptides corresponding to the calmodulin-binding domains of skeletal muscle myosin light chain kinase and human erythrocyte Ca2+ pump interact with and permeabilize liposomes and cell membranes.
Melanoma
The plasma membrane Ca(2+) pump PMCA4b inhibits the migratory and metastatic activity of BRAF mutant melanoma cells.
Melanoma
The Plasma Membrane Ca2+ Pump PMCA4b Regulates Melanoma Cell Migration through Remodeling of the Actin Cytoskeleton.
Metabolic Diseases
Roles of sarcoplasmic reticulum Ca2+ ATPase pump in the impairments of lymphatic contractile activity in a metabolic syndrome rat model.
Metabolic Syndrome
Early cardiac dysfunction is rescued by upregulation of SERCA2a pump activity in a rat model of metabolic syndrome.
Metabolic Syndrome
Metabolic Syndrome Abolishes Glucagon-Like Peptide 1 Receptor Agonist Stimulation of SERCA in Coronary Smooth Muscle.
Metabolic Syndrome
New Insights on the Role of SERCA During Vessel Remodeling in Metabolic Syndrome.
Metabolic Syndrome
Nox2 mediates high fat high sucrose diet-induced nitric oxide dysfunction and inflammation in aortic smooth muscle cells.
Metabolic Syndrome
OXIDATIVE STRESS IN CARDIOMYOCYTES CONTRIBUTES TO DECREASED SERCA2a ACTIVITY IN METABOLIC SYNDROME RATS.
Metabolic Syndrome
Oxidative stress in early metabolic syndrome impairs cardiac RyR2 and SERCA2a activity and modifies the interplay of these proteins during Ca2+ waves.
Metabolic Syndrome
Roles of sarcoplasmic reticulum Ca2+ ATPase pump in the impairments of lymphatic contractile activity in a metabolic syndrome rat model.
Mitochondrial Diseases
Acute rhabdomyolysis and inflammation.
Mitochondrial Diseases
Multifunctional Single-Layered Graphene Quantum Dots Used for Diagnosis of Mitochondrial Malfunction-Related Diseases.
Mitochondrial Myopathies
Calcium regulation and muscle disease.
Mitochondrial Myopathies
Changes in motor innervation and histochemical pattern of muscle fibers in some congenital myopathies.
Mitral Valve Insufficiency
Alteration of myocardial sarcoplasmic reticulum Ca2+-ATPase and Na+-Ca2+ exchanger expression in human left ventricular volume overload.
Mitral Valve Insufficiency
Gene delivery of sarcoplasmic reticulum calcium ATPase inhibits ventricular remodeling in ischemic mitral regurgitation.
Mitral Valve Insufficiency
Role of cAMP in modulating relaxation kinetics and the force-frequency relation in mitral regurgitation heart failure.
Mitral Valve Insufficiency
SERCA2a gene transfer enhances eNOS expression and activity in endothelial cells.
Mouth Neoplasms
Histone deacetylase inhibitors promote the expression of ATP2A3 gene in breast cancer cell lines.
Mouth Neoplasms
Plasma membrane Ca2+ ATPase isoform 1 down-regulated in human oral cancer.
Multiple Myeloma
Tipifarnib-induced apoptosis in acute myeloid leukemia and multiple myeloma cells is dependent on Ca2+ influx through plasma membrane Ca2+ channels.
Multiple Sclerosis
Mechanisms of neuronal damage in multiple sclerosis and its animal models: role of calcium pumps and exchangers.
Multiple Sclerosis
Muscle fiber type-specific myofibrillar actomyosin Ca2+ ATPase activity in multiple sclerosis.
Multiple Sclerosis
Pathological pain processing in mouse models of multiple sclerosis and spinal cord injury: contribution of plasma membrane calcium ATPase 2 (PMCA2).
Multiple Sclerosis
Plasma membrane calcium ATPase deficiency causes neuronal pathology in the spinal cord: a potential mechanism for neurodegeneration in multiple sclerosis and spinal cord injury.
Multiple Sclerosis
Reduced expression of plasma membrane calcium ATPase 2 and collapsin response mediator protein 1 promotes death of spinal cord neurons.
Multiple Sclerosis
Role of plasma membrane calcium ATPase 2 in spinal cord pathology.
Muscle Hypotonia
A novel PMCA3 mutation in an ataxic patient with hypomorphic phosphomannomutase 2 (PMM2) heterozygote mutations: Biochemical characterization of the pump defect.
Muscle Spasticity
Tail muscle parvalbumin content is decreased in chronic sacral spinal cord injured rats with spasticity.
Muscle Weakness
Aerobic exercise training improves skeletal muscle function and Ca2+ handling-related protein expression in sympathetic hyperactivity-induced heart failure.
Muscle Weakness
Biochemical changes in primary culture of skeletal muscle cells following dimethoate exposure.
Muscle Weakness
From excitation to intracellular Ca2+ movements in skeletal muscle: Basic aspects and related clinical disorders.
Muscle Weakness
Oxidative stress-induced dysregulation of excitation-contraction coupling contributes to muscle weakness.
Muscle Weakness
Reduced sarcoplasmic reticulum Ca2+ ATPase activity underlies skeletal muscle wasting in asthma.
Muscle Weakness
Restoration of SERCA ATPase prevents oxidative stress-related muscle atrophy and weakness.
Muscular Atrophy
Reduced sarcoplasmic reticulum Ca2+ ATPase activity underlies skeletal muscle wasting in asthma.
Muscular Atrophy
Restoration of Sarcoplasmic Reticulum Ca2+ ATPase (SERCA) Activity Prevents Age-Related Muscle Atrophy and Weakness in Mice.
Muscular Atrophy
Restoration of SERCA ATPase prevents oxidative stress-related muscle atrophy and weakness.
Muscular Atrophy
Sarcolipin deletion exacerbates soleus muscle atrophy and weakness in phospholamban overexpressing mice.
Muscular Atrophy
The Effect of Passive Movement on Denervated Soleus Highlights a Differential Nerve Control on SERCA and MyHC Isoforms.
Muscular Atrophy, Spinal
Elevated calmodulin levels and reduced calmodulin-stimulated calcium-ATPase in Duchenne progressive muscular dystrophy.
Muscular Diseases
Acute rhabdomyolysis and inflammation.
Muscular Diseases
Characterization of sarcoplasmic reticulum Ca(2+) ATPase pumps in muscle of patients with myotonic dystrophy and with hypothyroid myopathy.
Muscular Diseases
Effect of Stem Cells, Ascorbic Acid and SERCA1a Gene Transfected Stem Cells in Experimentally Induced Type I Diabetic Myopathy.
Muscular Diseases
Elevated calmodulin levels and reduced calmodulin-stimulated calcium-ATPase in Duchenne progressive muscular dystrophy.
Muscular Diseases
Exome analysis identifies Brody myopathy in a family diagnosed with malignant hyperthermia susceptibility.
Muscular Diseases
Fast-twitch skeletal muscle fiber adaptation to SERCA1 deficiency in a Dutch Improved Red and White calf pseudomyotonia case.
Muscular Diseases
Identification of a missense mutation in the bovine ATP2A1 gene in congenital pseudomyotonia of Chianina cattle: an animal model of human Brody disease.
Muscular Diseases
Modulation of rabbit muscle sarcoplasmic reticulum Ca(2+)-ATPase activity by novel quercetin derivatives.
Muscular Diseases
Pinpointing oxidative stress behind the white striping myopathy: depletion of antioxidant defenses, accretion of oxidized proteins and impaired proteostasis.
Muscular Diseases
Sarcolipin deletion exacerbates soleus muscle atrophy and weakness in phospholamban overexpressing mice.
Muscular Diseases
Sarcoplasmic reticulum Ca2+ pumps in heart and diaphragm of cardiomyopathic hamster: effects of perindopril.
Muscular Diseases
SERCA pumps and human diseases.
Muscular Diseases
SERCA1 and calsequestrin storage myopathy: a new surplus protein myopathy.
Muscular Diseases
SERCA1 attenuates diaphragm relaxation and uptake rate of SERCA in rats with acute sepsis.
Muscular Disorders, Atrophic
Remarkable plasticity of Na(+), K(+)-ATPase, Ca(2+)-ATPase and SERCA contributes to muscle disuse atrophy resistance in hibernating Daurian ground squirrels.
Muscular Dystrophies
Abnormal response to calmodulin in vitro of dystrophic chicken muscle membrane Ca2+-ATPase activity.
Muscular Dystrophies
Calpain 3 deficiency affects SERCA expression and function in the skeletal muscle.
Muscular Dystrophies
Elevated whole muscle phosphatidylcholine: phosphatidylethanolamine ratio coincides with reduced SERCA activity in murine overloaded plantaris muscles.
Muscular Dystrophies
Identification of Small Ankyrin 1 as a Novel Sarco(endo)plasmic Reticulum Ca2+-ATPase 1 (SERCA1) Regulatory Protein in Skeletal Muscle.
Muscular Dystrophies
Lipogenesis mitigates dysregulated sarcoplasmic reticulum calcium uptake in muscular dystrophy.
Muscular Dystrophies
Membrane crystals of Ca2+-ATPase in sarcoplasmic reticulum of normal and dystrophic muscle.
Muscular Dystrophies
Membrane-bound enzymes of erythrocytes in human muscular dystrophy: (Na+ + K+-ATPase, Ca2+-ATPase, K+- and Ca2+-p-nitrophenylphosphatase.
Muscular Dystrophies
Mitigation of muscular dystrophy in mice by SERCA overexpression in skeletal muscle.
Muscular Dystrophies
Oxidative stress and muscular dystrophy.
Muscular Dystrophies
Phospholamban overexpression in mice causes a centronuclear myopathy-like phenotype.
Muscular Dystrophies
Postnatal development of Ca2+-sequestration by the sarcoplasmic reticulum of fast and slow muscles in normal and dystrophic mice.
Muscular Dystrophies
Sarcolipin overexpression impairs myogenic differentiation in Duchenne muscular dystrophy.
Muscular Dystrophies
Saturation of SERCA's lipid annulus may protect against its thermal inactivation.
Muscular Dystrophies
The enzymes of the red blood cell plasma membrane.
Muscular Dystrophies
The neonatal sarcoplasmic reticulum Ca(2+)-ATPase gives a clue to development and pathology in human muscles.
Muscular Dystrophies
[Changes in the ATP-ase activity of skeletal muscle nuclei of rabbits with dystrophy and following their delipidation]
Muscular Dystrophies
[Electron-cytochemical study of the localization and properties of ATPases in the isolated nuclei of rabbit skeletal muscle under normal conditions and in experimental muscular dystrophy]
Muscular Dystrophies
[Erythrocyte membrane proteins]
Muscular Dystrophy, Duchenne
DP71 and SERCA2 alteration in human neurons of a Duchenne muscular dystrophy patient.
Muscular Dystrophy, Duchenne
Elevated calmodulin levels and reduced calmodulin-stimulated calcium-ATPase in Duchenne progressive muscular dystrophy.
Muscular Dystrophy, Duchenne
Overexpression of SERCA1a in the mdx diaphragm reduces susceptibility to contraction induced damage.
Muscular Dystrophy, Duchenne
Sarcolipin haploinsufficiency prevents dystrophic cardiomyopathy in mdx mice.
Muscular Dystrophy, Duchenne
Sarcoplasmic reticulum Ca2+-ATPase and acylphosphatase activities in muscle biopsies from patients with Duchenne muscular dystrophy.
Muscular Dystrophy, Duchenne
Single SERCA2a Therapy Ameliorated Dilated Cardiomyopathy for 18 Months in a Mouse Model of Duchenne Muscular Dystrophy.
Myalgia
Ca2+-ATPase deficiency in a patient with an exertional muscle pain syndrome.
Myalgia
Investigation of the relationships between different enzymes and postmortem duck muscle tenderization.
Myocardial Infarction
Activin type II receptor ligand signaling inhibition after experimental ischemic heart failure attenuates cardiac remodeling and prevents fibrosis.
Myocardial Infarction
Cardioprotective effect of salvianolic acid B on large myocardial infarction mediated by reversing upregulation of leptin, endothelin pathways, and abnormal expression of SERCA2a, phospholamban in rats.
Myocardial Infarction
Changes in skeletal muscle SR Ca2+ pump in congestive heart failure due to myocardial infarction are prevented by angiotensin II blockade.
Myocardial Infarction
Circulating cytokine levels in mice with heart failure are etiology dependent.
Myocardial Infarction
Constitutive cardiac overexpression of sarcoplasmic/endoplasmic reticulum Ca2+-ATPase delays myocardial failure after myocardial infarction in rats at a cost of increased acute arrhythmias.
Myocardial Infarction
Decreased expression of cardiac sarcoplasmic reticulum Ca(2+)-pump ATPase in congestive heart failure due to myocardial infarction.
Myocardial Infarction
Differences in expression of sarcoplasmic reticulum Ca2+-ATPase and Na+-Ca2+ exchanger genes between adjacent and remote noninfarcted myocardium after myocardial infarction.
Myocardial Infarction
Digitoxin Attenuates Heart Failure, Reduces Myocardial Hypertrophy, and Preserves the Calcium-Binding Proteins in Infarcted Rats.
Myocardial Infarction
E3 Ubiquitin ligase NEDD4 family?regulatory network in cardiovascular disease.
Myocardial Infarction
Effects of chronic dobutamine on cardiac mechanics and biochemistry after myocardial infarction in rats.
Myocardial Infarction
Effects of sarcoplasmic reticulum Ca2+-ATPase overexpression in postinfarction rat myocytes.
Myocardial Infarction
Expression of SERCA isoform with faster Ca2+ transport properties improves postischemic cardiac function and Ca2+ handling and decreases myocardial infarction.
Myocardial Infarction
Heat Shock Protein 70 Protects the Heart from Ischemia/Reperfusion Injury through Inhibition of p38 MAPK Signaling.
Myocardial Infarction
In vivo effects of nitrosyl hydrogen on cardiac function and sarcoplasmic reticulum calcium pump (SERCA2a) in rats with heart failure after myocardial infarction.
Myocardial Infarction
Influence of long-term treatment of imidapril on mortality, cardiac function, and gene expression in congestive heart failure due to myocardial infarction.
Myocardial Infarction
Inhibition of carnitine synthesis modulates protein contents of the cardiac sarcoplasmic reticulum Ca2+-ATPase and hexokinase type I in rat hearts with myocardial infarction.
Myocardial Infarction
JNK/PI3K/Akt signaling pathway is involved in myocardial ischemia/reperfusion injury in diabetic rats: effects of salvianolic acid A intervention.
Myocardial Infarction
Lentiviral vector-mediated SERCA2 gene transfer protects against heart failure and left ventricular remodeling after myocardial infarction in rats.
Myocardial Infarction
lncRNA-ZFAS1 induces mitochondria-mediated apoptosis by causing cytosolic Ca2+ overload in myocardial infarction mice model.
Myocardial Infarction
Low-Dose Empagliflozin Improves Systolic Heart Function after Myocardial Infarction in Rats: Regulation of MMP9, NHE1, and SERCA2a.
Myocardial Infarction
Luteolin Modulates SERCA2a Leading to Attenuation of Myocardial Ischemia/ Reperfusion Injury via Sumoylation at Lysine 585 in Mice.
Myocardial Infarction
Luteolin modulates SERCA2a via Sp1 upregulation to attenuate myocardial ischemia/reperfusion injury in mice.
Myocardial Infarction
MicroRNAs and cardiac sarcoplasmic reticulum calcium ATPase-2 in human myocardial infarction: expression and bioinformatic analysis.
Myocardial Infarction
Mitigation of myocardial fibrosis by molecular cardiac surgery-mediated gene overexpression.
Myocardial Infarction
PMCA4 inhibition does not affect cardiac remodelling following myocardial infarction, but may reduce susceptibility to arrhythmia.
Myocardial Infarction
Primary Effect of SERCA 2a Gene Transfer on Conduction Reserve in Chronic Myocardial Infarction.
Myocardial Infarction
rAAV-asPLB transfer attenuates abnormal sarcoplasmic reticulum Ca2+ -ATPase activity and cardiac dysfunction in rats with myocardial infarction.
Myocardial Infarction
Sarcolemmal Ca2+-ATPase ability to transport Ca2+ gradually diminishes after myocardial infarction in the rat.
Myocardial Infarction
Sarcolemmal calcium transport in congestive heart failure due to myocardial infarction in rats.
Myocardial Infarction
Sarcoplasmic reticular Ca2+ pump ATPase activity in congestive heart failure due to myocardial infarction.
Myocardial Infarction
Separate mechanisms cause anemia in ischemic vs. nonischemic murine heart failure.
Myocardial Infarction
SERCA2a gene therapy in heart failure: an anti-arrhythmic positive inotrope.
Myocardial Infarction
SNX17 produces anti-arrhythmic effects by preserving functional SERCA2a protein in myocardial infarction.
Myocardial Infarction
Therapeutic Benefit and Gene Network Regulation by Combined Gene Transfer of Apelin, FGF2, and SERCA2a into Ischemic Heart.
Myocardial Infarction
Time course of changes in the expression of DHPR, RyR(2), and SERCA2 after myocardial infarction in the rat left ventricle.
Myocardial Infarction
Total Saponins of Aralia Elata (Miq) Seem Alleviate Calcium Homeostasis Imbalance and Endoplasmic Reticulum Stress-Related Apoptosis Induced by Myocardial Ischemia/Reperfusion Injury.
Myocardial Infarction
Velvet Antler Ameliorates Cardiac Function by Restoring Sarcoplasmic Reticulum Ca2+-ATPase Activity in Rats With Heart Failure After Myocardial Infarction.
Myocardial Infarction
Vitamins C and E attenuate apoptosis, beta-adrenergic receptor desensitization, and sarcoplasmic reticular Ca2+ ATPase downregulation after myocardial infarction.
Myocardial Infarction
[Effect of riboxine on the ATPase activity and adenine nucleotide content in the myocardium in experimental myocardial infarct]
Myocardial Infarction
[Lentiviral vector-mediated in vivo SERCA2a gene transfer improved cardiac function and remodeling of failing heart induced by myocardial infarction in the rat]
Myocardial Infarction
[The changes of cardioelectrical activity of rat with myocardial infarction receiving sarcoplasmic reticulum Ca(2+)-ATPase gene modified bone marrow stem cell transplantation by microelectrode array technology].
Myocardial Ischemia
An updated role of astragaloside IV in heart failure.
Myocardial Ischemia
Attenuation of Endoplasmic Reticulum Stress-Related Myocardial Apoptosis by SERCA2a Gene Delivery in Ischemic Heart Disease.
Myocardial Ischemia
Differential expression of sarcolipin protein during muscle development and cardiac pathophysiology.
Myocardial Ischemia
Gene Expression of the Na-Ca(2+) Exchanger, SERCA2a and Calsequestrin after Myocardial Ischemia in the Neonatal Rabbit Heart.
Myocardial Ischemia
Palmitylcarnitine inhibition of the calcium pump in cardiac sarcoplasmic reticulum: a possible role in myocardial ischemia.
Myocardial Ischemia
Possible mechanism responsible for mechanical dysfunction of ischemic myocardium: a role of oxygen free radicals.
Myocardial Ischemia
Protective effects of cyclopiazonic acid on ischemia-reperfusion injury in rabbit hearts.
Myocardial Ischemia
Therapeutic Benefit and Gene Network Regulation by Combined Gene Transfer of Apelin, FGF2, and SERCA2a into Ischemic Heart.
Myocardial Ischemia
[Effects of acupuncture at the points of the Pericardium Meridian on the activity of myocardial Ca2+-ATPase and gene expression in the rat of myocardial ischemia and reperfusion injury]
Myocardial Reperfusion Injury
Injury to the Ca2+ ATPase of the sarcoplasmic reticulum in anesthetized dogs contributes to myocardial reperfusion injury.
Myocardial Reperfusion Injury
Melatonin-Induced Protective Effects on Cardiomyocytes Against Reperfusion Injury Partly Through Modulation of IP3R and SERCA2a Via Activation of ERK1.
Myocardial Stunning
Effect of increased free [Mg2+]i with myocardial stunning on sarcoplasmic reticulum Ca(2+)-ATPase activity.
Myocardial Stunning
Increased activity of the sarcoplasmic reticular calcium pump in porcine stunned myocardium.
Myocardial Stunning
Involvement of the sarcoplasmic reticulum calcium pump in myocardial contractile dysfunction: comparison between chronic pressure-overload and stunning.
Myocardial Stunning
Is reduced SERCA2a expression detrimental or beneficial to postischemic cardiac function and injury? Evidence from heterozygous SERCA2a knockout mice.
Myocardial Stunning
Mechanisms underlying myocardial stunning.
Myocardial Stunning
The sarcoplasmic reticulum Ca(2+)-ATPase is depressed in stunned myocardium after ischemia-reperfusion, but remains functionally coupled to sarcoplasmic reticulum-bound glycolytic enzymes.
Myocarditis
An evidence for surface expression of an immunogenic epitope of sarcoplasmic/endoplasmic reticulum calcium-ATPase2a on antigen-presenting cells from naive mice in the mediation of autoimmune myocarditis.
Myocarditis
Cardiac protective effect of astragalus on viral myocarditis mice: comparison with perindopril.
Myocarditis
Cardiac sarcoplasmic reticulum calcium ATPase, an autoimmune antigen in experimental cardiomyopathy.
Myocarditis
Epitope Mapping of SERCA2a Identifies an Antigenic Determinant That Induces Mainly Atrial Myocarditis in A/J Mice.
Myocarditis
SR-Ca2+ ATPase as an autoimmunogen in experimental myocarditis.
Myocarditis
[Effects of Astragaloside in treating myocardial injury and myocardial Sarco/Endoplasmic Ca(2+)-ATPase of viral myocarditis mice]
Myopathies, Structural, Congenital
Detection of a new polymorphism in the plasma-membrane Ca2+ ATPase isoform-3 gene and its exclusion as a candidate for X-linked myotubular myopathy (MTM1).
Myopathies, Structural, Congenital
Diaphragm assessment in mice overexpressing phospholamban in slow-twitch type I muscle fibers.
Myopathy, Central Core
Changes in motor innervation and histochemical pattern of muscle fibers in some congenital myopathies.
Myositis
Acute rhabdomyolysis and inflammation.
Myotonia
From excitation to intracellular Ca2+ movements in skeletal muscle: Basic aspects and related clinical disorders.
Myotonia
Sarcoplasmic reticulum ATPase in tibialis anterior muscle from rats with experimental myotonia.
Myotonia Congenita
Immunochemical quantification of sarcoplasmic reticulum Ca(2+)-ATPase and calsequestrin in muscle biopsies from patients with myotonia congenita and paramyotonia congenita Eulenburg.
Myotonic Disorders
Immunochemical quantification of sarcoplasmic reticulum Ca(2+)-ATPase and calsequestrin in muscle biopsies from patients with myotonia congenita and paramyotonia congenita Eulenburg.
Myotonic Dystrophy
Altered mRNA splicing of the skeletal muscle ryanodine receptor and sarcoplasmic/endoplasmic reticulum Ca2+-ATPase in myotonic dystrophy type 1.
Myotonic Dystrophy
Characterization of sarcoplasmic reticulum Ca(2+) ATPase pumps in muscle of patients with myotonic dystrophy and with hypothyroid myopathy.
Myotonic Dystrophy
Deficiency of Na+/K(+)-ATPase and sarcoplasmic reticulum Ca(2+)-ATPase in skeletal muscle and cultured muscle cells of myotonic dystrophy patients.
Myotonic Dystrophy
Endoplasmic reticulum stress in myotonic dystrophy type 1 muscle.
Myotonic Dystrophy
Functional analysis of SERCA1b, a highly expressed SERCA1 variant in myotonic dystrophy type 1 muscle.
Myotonic Dystrophy
Ion transport in human skeletal muscle cells: disturbances in myotonic dystrophy and Brody's disease.
Myotonic Dystrophy
Molecular mechanisms responsible for aberrant splicing of SERCA1 in myotonic dystrophy type 1.
Myotonic Dystrophy
The neonatal sarcoplasmic reticulum Ca(2+)-ATPase gives a clue to development and pathology in human muscles.
Myotonic Dystrophy
Three-dimensional imaging in myotonic dystrophy type 1: Linking molecular alterations with disease phenotype.
Myotoxicity
Differential Effect of Articaine on Sarcoendoplasmic Reticulum Calcium Adenosine Triphosphatase of Medial Pterygoid Muscle.
Neoplasm Metastasis
A Ca2+-ATPase Regulates E-cadherin Biogenesis and Epithelial-Mesenchymal Transition in Breast Cancer Cells.
Neoplasm Metastasis
Aberrant SERCA3 expression during the colorectal adenoma-adenocarcinoma sequence.
Neoplasm Metastasis
Aberrant SERCA3 expression is closely linked to pathogenesis, invasion, metastasis, and prognosis of gastric carcinomas.
Neoplasm Metastasis
Epigenetic Modulation of SPCA2 Reverses Epithelial to Mesenchymal Transition in Breast Cancer Cells.
Neoplasm Metastasis
Loss of RhoA expression prevents proliferation and metastasis of SPCA1 lung cancer cells in vitro.
Neoplasm Metastasis
Novel role of Sarco/endoplasmic reticulum calcium ATPase 2 in development of colorectal cancer and its regulation by F36, a curcumin analog.
Neoplasm Metastasis
P38 MAPK Promotes Migration and Metastatic Activity of BRAF Mutant Melanoma Cells by Inducing Degradation of PMCA4b.
Neoplasm Metastasis
Plasma membrane calcium ATPase expression in human colon multistep carcinogenesis.
Neoplasm Metastasis
Sarco/endoplasmic reticulum calcium-ATPase 2 expression as a tumor marker in colorectal cancer.
Neoplasm Metastasis
SBF-1 exerts strong anticervical cancer effect through inducing endoplasmic reticulum stress-associated cell death via targeting sarco/endoplasmic reticulum Ca(2+)-ATPase 2.
Neoplasm Metastasis
shRNA-mediated knockdown of Bmi-1 inhibit lung adenocarcinoma cell migration and metastasis.
Neoplasm Metastasis
The calcium pump PMCA4 prevents epithelial-mesenchymal transition by inhibiting NFATc1-ZEB1 pathway in gastric cancer.
Neoplasm Metastasis
The plasma membrane Ca(2+) pump PMCA4b inhibits the migratory and metastatic activity of BRAF mutant melanoma cells.
Neoplasms
A Ca2+-ATPase Regulates E-cadherin Biogenesis and Epithelial-Mesenchymal Transition in Breast Cancer Cells.
Neoplasms
Aberrant SERCA3 expression is closely linked to pathogenesis, invasion, metastasis, and prognosis of gastric carcinomas.
Neoplasms
Activation of calcium oscillations by thapsigargin in parotid acinar cells.
Neoplasms
Adenosinetriphosphatase as the factor inhibiting the enzymic synthesis of diphosphopyridine nucleotides in the tissues of rats and mice with transplanted tumours.
Neoplasms
Altered Endoplasmic Reticulum Calcium Pump Expression during Breast Tumorigenesis.
Neoplasms
Annonacin promotes selective cancer cell death via NKA-dependent and SERCA-dependent pathways.
Neoplasms
Anticancer ruthenium(III) complex KP1019 interferes with ATP-dependent Ca2+ translocation by sarco-endoplasmic reticulum Ca2+-ATPase (SERCA).
Neoplasms
Aralia elata var. mandshurica (Rupr. & Maxim.) J.Wen: An overview of pharmacological studies.
Neoplasms
Artemisinin-Resistant Mutants of Toxoplasma gondii Have Altered Calcium Homeostasis.
Neoplasms
Assignment of 20 microsatellite markers to the porcine linkage map.
Neoplasms
ATP2A3 gene as an important player for resveratrol anticancer activity in breast cancer cells.
Neoplasms
Attenuation of the upregulation of NF??B and AP?1 DNA?binding activities induced by tunicamycin or hypoxia/reoxygenation in neonatal rat cardiomyocytes by SERCA2a overexpression.
Neoplasms
Blockade of Oncogenic NOTCH1 with the SERCA Inhibitor CAD204520 in T Cell Acute Lymphoblastic Leukemia.
Neoplasms
Ca2+ translocation in Ehrlich ascites tumor cells.
Neoplasms
Cab45S promotes cell proliferation through SERCA2b inhibition and Ca2+ signaling.
Neoplasms
Calcium metabolism in Ehrlich Ascites tumour cells.
Neoplasms
Calcium permeability of Ehrlich ascites tumour cell plasma membrane in vivo.
Neoplasms
Calcium pump expression in human bone and soft tissue tumours.
Neoplasms
Calcium transport by HeLa cell mitochondria.
Neoplasms
Cardiac remodeling and dysfunction in nephrotic syndrome.
Neoplasms
Celecoxib inhibits interleukin-12 alphabeta and beta2 folding and secretion by a novel COX2-independent mechanism involving chaperones of the endoplasmic reticulum.
Neoplasms
Changes in intracellular Ca2+ and pH in response to thapsigargin in human glioblastoma cells and normal astrocytes.
Neoplasms
Clinical significance of P-class pumps in cancer.
Neoplasms
Complementary Genomic Screens Identify SERCA as a Therapeutic Target in NOTCH1 Mutated Cancer.
Neoplasms
Correlated expression of the 97 kDa sarcoendoplasmic reticulum Ca(2+)-ATPase and Rap1B in platelets and various cell lines.
Neoplasms
Critical roles of hydrophobicity and orientation of side chains for inactivation of sarcoplasmic reticulum Ca2+-ATPase with thapsigargin and thapsigargin analogs.
Neoplasms
Differential expression of PMCA2 mRNA isoforms in a cohort of Spanish patients with breast tumor types.
Neoplasms
Direct detection of SERCA calcium transport and small-molecule inhibition in giant unilamellar vesicles.
Neoplasms
Discovery of novel SERCA inhibitors by virtual screening of a large compound library.
Neoplasms
Disruption of the interaction between PMCA2 and calcineurin triggers apoptosis and enhances paclitaxel-induced cytotoxicity in breast cancer cells.
Neoplasms
Drug Interactions With the Ca2+-ATPase From Sarco(Endo)Plasmic Reticulum (SERCA).
Neoplasms
Dual mechanisms of sHA 14-1 in inducing cell death through endoplasmic reticulum and mitochondria.
Neoplasms
Effect of drug resistance modulator, NO donor, on membrane structure and function of membrane-bound Ca2+-activated Mg2+-dependent ATPase.
Neoplasms
Effect of Pro-Inflammatory Cytokines on Regulation of Sarcoplasmic Reticulum Ca2+ Reuptake in Human Airway Smooth Muscle.
Neoplasms
Endoplasmic reticulum calcium pumps and cancer cell differentiation.
Neoplasms
Endoplasmic Reticulum Calcium Pumps and Tumor Cell Differentiation.
Neoplasms
Endoplasmic reticulum calcium transport ATPase expression during differentiation of colon cancer and leukaemia cells.
Neoplasms
Endothelial cell intracellular Ca2+ concentration is increased upon breast tumor cell contact and mediates tumor cell transendothelial migration.
Neoplasms
Epigenetic Modulation of SPCA2 Reverses Epithelial to Mesenchymal Transition in Breast Cancer Cells.
Neoplasms
Epigenetic regulation of the human ATP2A3 gene promoter in gastric and colon cancer cell lines.
Neoplasms
ER functions of oncogenes and tumor suppressors: Modulators of intracellular Ca(2+) signaling.
Neoplasms
Ethyl 2-Amino-6-(3,5-dimethoxyphenyl)-4-(2-ethoxy-2-oxoethyl)-4H-chromene-3-carboxylate (CXL017): a novel scaffold that resensitizes multidrug resistant leukemia cells to chemotherapy.
Neoplasms
Evidence for a novel parathyroid hormone-related protein in fetal lamb parathyroid glands and sheep placenta: comparisons with a similar protein implicated in humoral hypercalcaemia of malignancy.
Neoplasms
Expression of calcium pumps is differentially regulated by histone deacetylase inhibitors and estrogen receptor alpha in breast cancer cells.
Neoplasms
Expression of endomembrane calcium pumps in colon and gastric cancer cells. Induction of SERCA3 expression during differentiation.
Neoplasms
FCY-302, a Novel Small Molecule, Induces Apoptosis in Leukemia and Myeloma Cells by Attenuating Key Antioxidant and Mitochondrial Enzymes.
Neoplasms
Gene expression profiles of luteal phase fallopian tube epithelium from BRCA mutation carriers resemble high-grade serous carcinoma.
Neoplasms
Growth inhibition of human tumor cells in soft-agar cultures by treatment with low levels of adenosine 5'-triphosphate.
Neoplasms
Haploinsufficiency of Atp2a2, encoding the sarco(endo)plasmic reticulum Ca2+-ATPase isoform 2 Ca2+ pump, predisposes mice to squamous cell tumors via a novel mode of cancer susceptibility.
Neoplasms
Hepatitis B virus-related insertional mutagenesis implicates SERCA1 gene in the control of apoptosis.
Neoplasms
Herpesviral G protein-coupled receptors activate NFAT to induce tumor formation via inhibiting the SERCA calcium ATPase.
Neoplasms
Highly cooperative dependence of sarco/endoplasmic reticulum calcium ATPase (SERCA) 2a pump activity on cytosolic calcium in living cells.
Neoplasms
Histone deacetylase inhibitor- and PMA-induced upregulation of PMCA4b enhances Ca2+ clearance from MCF-7 breast cancer cells.
Neoplasms
Hsp60 and IL-8 axis promotes apoptosis resistance in cancer.
Neoplasms
Induction of cell differentiation activates transcription of the Sarco/Endoplasmic Reticulum calcium-ATPase 3 gene (ATP2A3) in gastric and colon cancer cells.
Neoplasms
Inhibition of ezrin causes PKC?-mediated internalization of erbb2/HER2 tyrosine kinase in breast cancer cells.
Neoplasms
Investigation of dose-dependent effects of berberine against renal ischemia/reperfusion injury in experimental diabetic rats.
Neoplasms
Isoform-specific up-regulation of plasma membrane Ca(2+)ATPase expression during colon and gastric cancer cell differentiation.
Neoplasms
LINC01619 promotes non-small cell lung cancer development via regulating PAX6 by suppressing microRNA-129-5p.
Neoplasms
Lipopolysaccharide acutely suppresses right-ventricular strain in rats with pulmonary artery hypertension.
Neoplasms
Loss of endoplasmic reticulum calcium pump expression in choroid plexus tumours.
Neoplasms
Loss of the Atp2c1 secretory pathway Ca(2+)-ATPase (SPCA1) in mice causes Golgi stress, apoptosis, and midgestational death in homozygous embryos and squamous cell tumors in adult heterozygotes.
Neoplasms
Markers of squamous cell carcinoma in sarco/endoplasmic reticulum Ca(2+) ATPase 2 heterozygote mice keratinocytes.
Neoplasms
Molecular dynamics in mouse atrial tumor sarcoplasmic reticulum.
Neoplasms
Multiplicity of cell response to the BAI strain A (myeloblastosis) avian tumor virus. IV. Ultrastructural characters of the thymus in myeloblastosis and the adenosinetriphosphatase activity of thymic cells and associated virus.
Neoplasms
Multiplicity of cell response to the BAI strain A (myeloblastosis) avian tumor virus. VI. Ultrastructural aspects of adenosinetriphosphatase activity of nephroblastoma cells and virus.
Neoplasms
N-Desmethyldauricine Induces Autophagic Cell Death in Apoptosis-Defective Cells via Ca(2+) Mobilization.
Neoplasms
Nifetepimine, a dihydropyrimidone, ensures CD4+ T cell survival in tumor micro-environment by maneuvering Sarco(endo)plasmic reticulum Ca2+ ATPase (SERCA).
Neoplasms
Novel allelic mutations in murine Serca2 induce differential development of squamous cell tumors.
Neoplasms
Novel functional interaction between the plasma membrane Ca2+ pump 4b and the proapoptotic tumor suppressor Ras-associated factor 1 (RASSF1).
Neoplasms
Novel phenolic inhibitors of the sarco/endoplasmic reticulum calcium ATPase: identification and characterization by quantitative structure-activity relationship modeling and virtual screening.
Neoplasms
Novel role of Sarco/endoplasmic reticulum calcium ATPase 2 in development of colorectal cancer and its regulation by F36, a curcumin analog.
Neoplasms
Nox2 mediates high fat high sucrose diet-induced nitric oxide dysfunction and inflammation in aortic smooth muscle cells.
Neoplasms
One-megabase yeast artificial chromosome and 400-kilobase cosmid-phage contigs containing the von Hippel-Lindau tumor suppressor and Ca(2+)-transporting adenosine triphosphatase isoform 2 genes.
Neoplasms
Original association of ion transporters mediates the ECM-induced breast cancer cell survival: Kv10.1-Orai1-SPCA2 partnership.
Neoplasms
Ovarian Metabolic activity in Dehydroepiandrosterone-Induced Polycystic Ovary in Wistar rats Treated with Aspirin.
Neoplasms
p53 and Ca(2+) signaling from the endoplasmic reticulum: partners in anti-cancer therapies.
Neoplasms
Phenotypes of SERCA and PMCA knockout mice.
Neoplasms
Physiological functions of plasma membrane and intracellular Ca2+ pumps revealed by analysis of null mutants.
Neoplasms
Plasma levels of tumor necrosis factor-? and interleukin-6 are associated with diastolic heart failure through downregulation of sarcoplasmic reticulum Ca2+ ATPase.
Neoplasms
Plasma membrane Ca2+ ATPase isoform 1 down-regulated in human oral cancer.
Neoplasms
Plasma Membrane Ca2+ ATPase Isoform 4 (PMCA4) Has an Important Role in Numerous Hallmarks of Pancreatic Cancer.
Neoplasms
Plasma membrane Ca2+-permeable channels and sodium/calcium exchangers in tumorigenesis and tumor development of the upper gastrointestinal tract.
Neoplasms
Plasma membrane calcium ATPase 4 and the remodeling of calcium homeostasis in human colon cancer cells.
Neoplasms
Plasma membrane calcium ATPase expression in human colon multistep carcinogenesis.
Neoplasms
Plasma membrane calcium pumps and their emerging roles in cancer.
Neoplasms
Plasma membrane calcium-ATPase 2 and 4 in human breast cancer cell lines.
Neoplasms
Platelet-derived growth factor isoforms AA, AB, and BB differentially activate poly r(I):r(C)-induced genes in human fibroblast FS4 cells.
Neoplasms
PMCA2 regulates apoptosis during mammary gland involution and predicts outcome in breast cancer.
Neoplasms
PMCA2 regulates HER2 protein kinase localization and signaling and promotes HER2-mediated breast cancer.
Neoplasms
PMCA2 silencing potentiates MDA-MB-231 breast cancer cell death initiated with the Bcl-2 inhibitor ABT-263.
Neoplasms
PMCA4b as tumor suppressor: The Ca
Neoplasms
Prognostic significance of left ventricular diastolic function in burn patients.
Neoplasms
Quantification of ATP-producing and consuming processes of Ehrlich ascites tumour cells.
Neoplasms
Reduced SERCA Function Preferentially Affects Wnt Signaling by Retaining E-Cadherin in the Endoplasmic Reticulum.
Neoplasms
Regulation of sarco(endo)plasmic reticulum Ca(2+)-ATPase and calsequestrin gene expression in the heart.
Neoplasms
Resistance to tumor necrosis factor-induced cell death mediated by PMCA4 deficiency.
Neoplasms
Resveratrol Specifically Kills Cancer Cells by a Devastating Increase in the Ca2+ Coupling Between the Greatly Tethered Endoplasmic Reticulum and Mitochondria.
Neoplasms
Role of sarco/endoplasmic reticulum calcium content and calcium ATPase activity in the control of cell growth and proliferation.
Neoplasms
Sarco/Endoplasmic Reticulum Calcium ATPase Inhibitors: Beyond Anticancer Perspective.
Neoplasms
Sarco/endoplasmic reticulum calcium-ATPase 2 expression as a tumor marker in colorectal cancer.
Neoplasms
Secretory pathway stress responses as possible mechanisms of disease involving Golgi Ca2+ pump dysfunction.
Neoplasms
Selective Blockade of Transport via SERCA Inhibition: The Answer for Oncogenic Forms of Notch?
Neoplasms
SERCA and P-glycoprotein inhibition and ATP depletion are necessary for celastrol-induced autophagic cell death and collateral sensitivity in multidrug-resistant tumor cells.
Neoplasms
SERCA control of cell death and survival.
Neoplasms
Squamous cell tumors in mice heterozygous for a null allele of Atp2a2, encoding the sarco(endo)plasmic reticulum Ca2+-ATPase isoform 2 Ca2+ pump.
Neoplasms
Src tyrosine kinase mediates stimulation of Raf-1 and mitogen-activated protein kinase by the tumor promoter thapsigargin.
Neoplasms
Store-independent activation of Orai1 by SPCA2 in mammary tumors.
Neoplasms
Structural Changes of Sarco/Endoplasmic Reticulum Ca2+-ATPase Induced by Rutin Arachidonate: A Molecular Dynamics Study.
Neoplasms
Structure, function and subcellular localization of a human platelet Ca2+-ATPase.
Neoplasms
Structure-based virtual screening for novel inhibitors of the sarco/endoplasmic reticulum calcium ATPase and their experimental evaluation.
Neoplasms
Survival of Cancer Stem-Like Cells Under Metabolic Stress via CaMK2?-mediated Upregulation of Sarco/Endoplasmic Reticulum Calcium ATPase Expression.
Neoplasms
Susceptibility of lysosomes to rupture is a determinant for plasma membrane disruption in tumor necrosis factor alpha-induced cell death.
Neoplasms
Switching to instant black coffee modulates sodium selenite-induced cataract in rats.
Neoplasms
Synthesis, computational docking and biological evaluation of celastrol derivatives as dual inhibitors of SERCA and P-glycoprotein in cancer therapy.
Neoplasms
Thapsigargin--from Thapsia L. to mipsagargin.
Neoplasms
The Ca2+-transporting activity of rat liver microsomes in response to protein undernutrition: implications for liver tumor promotion.
Neoplasms
The calcium pump plasma membrane Ca(2+)-ATPase 2 (PMCA2) regulates breast cancer cell proliferation and sensitivity to doxorubicin.
Neoplasms
The Endoplasmic Reticulum and Calcium Homeostasis in Pancreatic Beta Cells.
Neoplasms
The expression of the sarco/endoplasmic reticulum Ca2+-ATPases in thyroid and its down-regulation following neoplastic transformation.
Neoplasms
The Focal Nature of Darier's Disease Lesions: Calcium Pumps, Stress, and Mutation?
Neoplasms
The Golgi calcium pump secretory pathway calcium ATPase 1 (SPCA1) is a key regulator of insulin-like growth factor receptor (IGF1R) processing in the basal-like breast cancer cell line MDA-MB-231.
Neoplasms
The loss of sarco/endoplasmic reticulum calcium transport ATPase 3 expression is an early event during the multistep process of colon carcinogenesis.
Neoplasms
The SERCA pump as a therapeutic target: making a "smart bomb" for prostate cancer.
Neoplasms
Trilobolide-porphyrin conjugates: on synthesis and biological effects evaluation.
Neoplasms
Tumor necrosis factor-alpha decreases sarcoplasmic reticulum Ca2+-ATPase expressions via the promoter methylation in cardiomyocytes*
Neoplasms
Tumour promoter tert-butyl-hydroperoxide induces peroxynitrite formation in human erythrocytes.
Neoplasms
[Activity of water-soluble adenosinetriphosphatase in transplanted tumors and in the spleen.]
Neoplasms
[Actomyosin from a low-differentiation skeletal muscle tumor]
Neoplasms
[Adenosinetriphosphatase activity of nuclear envelopes and from the cells of rat liver, Zaigdel hepatoma of rats and Ehrlich ascites tumour of mice]
Neoplasms
[Behavior of adenosinetriphosphatase activity in cerebral tumor.]
Neoplasms
[Cytochemical determination of adenosinetriphosphatase (ATP-ase) in the cells of an ascites tumor in the mouse.]
Neoplasms
[Dependence of adhesive properties on Ca2+-ATPase activity in tumor cells]
Neoplasms
[Expression of SERCA pumps during cell differentiation and tumorigenesis: application to colonic carcinogenesis]
Neoplasms
[Fibrolamellar liver carcinoma]
Neoplasms
[HCO3-sensitive adenosinetriphosphatase from ascites tumour cells]
Neoplasms
[Na+,K+-ATPase and Ca2+-ATPase isozymes in malignant neoplasms]
Neoplasms, Squamous Cell
Phenotypes of SERCA and PMCA knockout mice.
Neoplasms, Squamous Cell
Physiological functions of plasma membrane and intracellular Ca2+ pumps revealed by analysis of null mutants.
Nephrolithiasis
[Lipid peroxidation and Ca-dependent ATPase activity in the microsomal fraction of renal tissue in patients with nephrolithiasis and chronic pyelonephritis]
Neural Tube Defects
Secretory pathway calcium ATPase 1 (SPCA1) controls mouse neural tube closure by regulating cytoskeletal dynamics.
Neuralgia
Pathological pain processing in mouse models of multiple sclerosis and spinal cord injury: contribution of plasma membrane calcium ATPase 2 (PMCA2).
Neuralgia
Schekwanglupaside C, a new lupane saponin from Schefflera kwangsiensis, is a potent activator of sarcoplasmic reticulum Ca2+-ATPase.
Neuritis
[Expression of plasma membrane Ca(2+)-ATPase isoform 2 in spiral ganglion cells of newborn rats.]
Neurobehavioral Manifestations
Dysregulation of presynaptic calcium and synaptic plasticity in a mouse model of 22q11 deletion syndrome.
Neuroblastoma
Depletion of intracellular calcium stores is toxic to SH-SY5Y neuronal cells.
Neuroblastoma
Influence of inositol 1,4,5-trisphosphate and guanine nucleotides on intracellular calcium release within the N1E-115 neuronal cell line.
Neuroblastoma
Interaction between acylphosphatase and SERCA in SH-SY5Y cells.
Neuroblastoma
PMCA4 (ATP2B4) mutation in familial spastic paraplegia causes delay in intracellular calcium extrusion.
Neuroblastoma
Regulation of the sarco/endoplasmic reticulum Ca(2+)-ATPase (SERCA) 2 gene transcript in neuronal cells.
Neuroblastoma
RNA--induced silencing of the plasma membrane Ca2+-ATPase 2 in neuronal cells: effects on Ca2+ homeostasis and cell viability.
Neuroblastoma
Sarco(endo)plasmic reticulum ATPase is a molecular partner of Wolfram syndrome 1 protein, which negatively regulates its expression.
Neuroblastoma
Silencing the SPCA1 (secretory pathway Ca2+-ATPase isoform 1) impairs Ca2+ homeostasis in the Golgi and disturbs neural polarity.
Neurodegenerative Diseases
A Role for SERCA Pumps in the Neurobiology of Neuropsychiatric and Neurodegenerative Disorders.
Neurodegenerative Diseases
Schekwanglupaside C, a new lupane saponin from Schefflera kwangsiensis, is a potent activator of sarcoplasmic reticulum Ca2+-ATPase.
Nevus
Congenital acantholytic dyskeratotic epidermal naevus following Blaschko's lines versus segmental Darier's disease.
Nevus
The plasma membrane Ca(2+) pump PMCA4b inhibits the migratory and metastatic activity of BRAF mutant melanoma cells.
Niemann-Pick Disease, Type A
Sphingomyelin-induced inhibition of the plasma membrane calcium ATPase causes neurodegeneration in type A Niemann-Pick disease.
Niemann-Pick Diseases
Sphingomyelin-induced inhibition of the plasma membrane calcium ATPase causes neurodegeneration in type A Niemann-Pick disease.
Non-alcoholic Fatty Liver Disease
Correction to: Matrine attenuates endoplasmic reticulum stress and mitochondrion dysfunction in nonalcoholic fatty liver disease by regulating SERCA pathway.
Non-alcoholic Fatty Liver Disease
Matrine attenuates endoplasmic reticulum stress and mitochondrion dysfunction in nonalcoholic fatty liver disease by regulating SERCA pathway.
Non-alcoholic Fatty Liver Disease
Mesenchymal stromal cells protect hepatocytes from lipotoxicity through alleviation of endoplasmic reticulum stress by restoring SERCA activity.
Non-alcoholic Fatty Liver Disease
MicroRNA-30b Regulates Insulin Sensitivity by Targeting SERCA2b in Non-alcoholic Fatty Liver Disease.
Non-alcoholic Fatty Liver Disease
Sarco(endo)plasmic reticulum Ca2+-ATPase 2b is a major regulator of endoplasmic reticulum stress and glucose homeostasis in obesity.
Obesity
ATP consumption by sarcoplasmic reticulum Ca2+ pumps accounts for 50% of resting metabolic rate in mouse fast and slow twitch skeletal muscle.
Obesity
ATP consumption by sarcoplasmic reticulum Ca²? pumps accounts for 40-50% of resting metabolic rate in mouse fast and slow twitch skeletal muscle.
Obesity
Calcium and magnesium ATPase activities in women with varying BMIs.
Obesity
Cardiac contractile dysfunction in Lep/Lep obesity is accompanied by NADPH oxidase activation, oxidative modification of sarco(endo)plasmic reticulum Ca2+-ATPase and myosin heavy chain isozyme switch.
Obesity
Elevated whole muscle phosphatidylcholine: phosphatidylethanolamine ratio coincides with reduced SERCA activity in murine overloaded plantaris muscles.
Obesity
Impaired calcium metabolism associated with hypertension in Zucker obese rats.
Obesity
Involvement of L-type calcium channel and SERCA2A in myocardial dysfunction induced by obesity.
Obesity
Nox2 mediates high fat high sucrose diet-induced nitric oxide dysfunction and inflammation in aortic smooth muscle cells.
Obesity
Obesity induces upregulation of genes involved in myocardial Ca2+ handling.
Obesity
Phospholamban Deficiency Does Not Alter Skeletal Muscle SERCA Pumping Efficiency or Predispose Mice to Diet-Induced Obesity.
Obesity
Phospholipid methylation regulates muscle metabolic rate through Ca2+ transport efficiency.
Obesity
Sarco(endo)plasmic reticulum Ca2+-ATPase 2b is a major regulator of endoplasmic reticulum stress and glucose homeostasis in obesity.
Obesity
SERCA2 Deficiency Impairs Pancreatic ? Cell Function in Response to Diet-Induced Obesity.
Obesity
Sleeve gastrectomy in obese Wistar rats improves diastolic function and promotes cardiac recovery independent of weight loss.
Obesity
THADA Regulates the Organismal Balance between Energy Storage and Heat Production.
Oligospermia
Reduced activity of Mg2+- and Ca2+-dependent adenosine triphosphatase in seminal fluid of patients with oligozoospermia.
Osteoarthritis
Autophagy induction and CHOP under-expression promotes survival of fibroblasts from rheumatoid arthritis patients under endoplasmic reticulum stress.
Osteoporosis
Intracellular Ca2+ signaling mediates IGF-1-induced osteogenic differentiation in bone marrow mesenchymal stem cells.
Osteosarcoma
Calpain mobilizes Atg9/Bif-1 vesicles from Golgi stacks upon autophagy induction by thapsigargin.
Osteosarcoma
RAC1-Dependent ORAI1 Translocation to the Leading Edge Supports Lamellipodia Formation and Directional Persistence.
Ototoxicity
Correlation of increased activities of Na+, K+-ATPase and Ca2+-ATPase with the reversal of cisplatin ototoxicity induced by D-methionine in guinea pigs.
Ovarian Neoplasms
Curcumin induces apoptosis by inhibiting sarco/endoplasmic reticulum Ca(2+) ATPase activity in ovarian cancer cells.
Ovarian Neoplasms
Gene expression profiles of luteal phase fallopian tube epithelium from BRCA mutation carriers resemble high-grade serous carcinoma.
p-type ca2+ transporter deficiency
Ablation of plasma membrane Ca(2+)-ATPase isoform 4 prevents development of hypertrophy in a model of hypertrophic cardiomyopathy.
p-type ca2+ transporter deficiency
Ca2+-ATPase deficiency in a patient with an exertional muscle pain syndrome.
p-type ca2+ transporter deficiency
Calcium upregulation by percutaneous administration of gene therapy in cardiac disease (CUPID Trial), a first-in-human phase 1/2 clinical trial.
p-type ca2+ transporter deficiency
Distinct phenotypes among plasma membrane Ca2+-ATPase knockout mice.
p-type ca2+ transporter deficiency
Fast-twitch skeletal muscle fiber adaptation to SERCA1 deficiency in a Dutch Improved Red and White calf pseudomyotonia case.
p-type ca2+ transporter deficiency
Hailey-Hailey disease: investigation of a possible compensatory SERCA2 up-regulation and analysis of SPCA1, p63, and IRF6 expression.
p-type ca2+ transporter deficiency
Heterozygous disruption of SERCA2a is not associated with impairment of cardiac performance in humans: implications for SERCA2a as a therapeutic target in heart failure.
p-type ca2+ transporter deficiency
Plasma membrane Ca2+ ATPase 4 is required for sperm motility and male fertility.
p-type ca2+ transporter deficiency
Plasma membrane calcium ATPase deficiency causes neuronal pathology in the spinal cord: a potential mechanism for neurodegeneration in multiple sclerosis and spinal cord injury.
p-type ca2+ transporter deficiency
Prominent heart organ-level performance deficits in a genetic model of targeted severe and progressive SERCA2 deficiency.
p-type ca2+ transporter deficiency
Resistance to tumor necrosis factor-induced cell death mediated by PMCA4 deficiency.
p-type ca2+ transporter deficiency
Restoration of calcium handling properties of adult cardiac myocytes from hypertrophied hearts.
p-type ca2+ transporter deficiency
Sarco/endoplasmic reticulum Ca2+-ATPase (SERCA) activity is required for V(D)J recombination.
p-type ca2+ transporter deficiency
SERCA2 Deficiency Impairs Pancreatic ? Cell Function in Response to Diet-Induced Obesity.
p-type ca2+ transporter deficiency
SERCA2 Haploinsufficiency in a Mouse Model of Darier Disease Causes a Selective Predisposition to Heart Failure.
p-type ca2+ transporter deficiency
SERCA2 regulates non-CF and CF airway epithelial cell response to ozone.
p-type ca2+ transporter deficiency
SPCA1 governs the stability of TMEM165 in Hailey-Hailey disease.
p-type ca2+ transporter deficiency
Susceptibility of lysosomes to rupture is a determinant for plasma membrane disruption in tumor necrosis factor alpha-induced cell death.
Pancreatic Neoplasms
Glycolytic ATP fuels the plasma membrane calcium pump critical for pancreatic cancer cell survival.
Pancreatic Neoplasms
Plasma Membrane Ca2+ ATPase Isoform 4 (PMCA4) Has an Important Role in Numerous Hallmarks of Pancreatic Cancer.
Pancreatic Neoplasms
The Plasma Membrane Calcium Pump in Pancreatic Cancer Cells Exhibiting the Warburg Effect Relies on Glycolytic ATP.
Pancreatitis
Effect of Chaiqinchengqi decoction on sarco/endoplasmic reticulum Ca2+-ATPase mRNA expression of pancreatic tissues in acute pancreatitis rats.
Pancreatitis
Effect of Qingyitang on activity of intracellular Ca2+-Mg2+-ATPase in rats with acute pancreatitis.
Pancreatitis
Parenchymal pressure injury Ca2+ entry mechanism in pancreatitis.
Pancreatitis
THE M-RNA, EXPRESSION OF SERCA2 AND NCX1 IN THE PROCESS OF PHARMACOLOGICAL CELL PROTECTION IN EXPERIMENTAL ACUTE PANCREATITIS INDUCED BY TAUROCHOLATE.
Paralysis
Analysis of conditional paralytic mutants in Drosophila sarco-endoplasmic reticulum calcium ATPase reveals novel mechanisms for regulating membrane excitability.
Paralysis
From excitation to intracellular Ca2+ movements in skeletal muscle: Basic aspects and related clinical disorders.
Paralysis
Sarco(endo)plasmic reticulum calcium pump isoforms in paralyzed rat slow muscle.
Paralysis
Stop the crop: Insights into the insecticidal mode of action of cinnamodial against mosquitoes.
Paralysis
Thyrotoxic periodic paralysis. Periodic variation in the muscle calcium pump activity.
Paralysis
[Modifications of myocardial adenosinetriphosphatase activity induced by sodium, potassium, calcium and magnesium in sudden death caused by so-called cardiac paralysis.]
Paraplegia
Increased susceptibility to ventricular arrhythmias is associated with changes in Ca2+ regulatory proteins in paraplegic rats.
Paraplegia
PMCA4 (ATP2B4) mutation in familial spastic paraplegia causes delay in intracellular calcium extrusion.
Paraplegia
PMCA4 (ATP2B4) mutation in familial spastic paraplegia.
Parasitemia
Direct exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) increases infectivity of human erythrocytes to a malarial parasite.
Parasitemia
Examining Plasmodium falciparum and P. vivax clearance subsequent to antimalarial drug treatment in the Myanmar-China border area based on quantitative real-time polymerase chain reaction.
Parkinson Disease
A new target for Parkinson's disease: Small molecule SERCA activator CDN1163 ameliorates dyskinesia in 6-OHDA-lesioned rats.
Parkinson Disease
Downregulation of PMCA2 increases the vulnerability of midbrain neurons to mitochondrial complex I inhibition.
Parkinson Disease
Oxidative modification impairs SERCA activity in Drosophila and human cell models of Parkinson's disease.
Parkinson Disease
Reduced Cytosolic Calcium as an Early Decisive Cellular State in Parkinson's Disease and Synucleinopathies.
Parkinsonian Disorders
A novel isoform of the secretory pathway Ca2+,Mn(2+)-ATPase, hSPCA2, has unusual properties and is expressed in the brain.
Pemphigus
Mechanisms of synergy of autoantibodies to M3 muscarinic acetylcholine receptor and secretory pathway Ca2+/Mn2+-ATPase isoform 1 in patients with non-desmoglein pemphigus vulgaris.
Pemphigus
Mutations in ATP2C1, encoding a calcium pump, cause Hailey-Hailey disease.
Pemphigus, Benign Familial
A novel isoform of the secretory pathway Ca2+,Mn(2+)-ATPase, hSPCA2, has unusual properties and is expressed in the brain.
Pemphigus, Benign Familial
Actin reorganization is abnormal and cellular ATP is decreased in Hailey-Hailey keratinocytes.
Pemphigus, Benign Familial
ATP2C1 gene mutations in Hailey-Hailey disease and possible roles of SPCA1 isoforms in membrane trafficking.
Pemphigus, Benign Familial
Autosomal-dominant calcium ATPase disorders.
Pemphigus, Benign Familial
Calcium in the Golgi apparatus.
Pemphigus, Benign Familial
Characterization of Hailey-Hailey Disease-mutants in presence and absence of wild type SPCA1 using Saccharomyces cerevisiae as model organism.
Pemphigus, Benign Familial
Diseases involving the Golgi calcium pump.
Pemphigus, Benign Familial
Effect of Hailey-Hailey Disease mutations on the function of a new variant of human secretory pathway Ca2+/Mn2+-ATPase (hSPCA1).
Pemphigus, Benign Familial
Exacerbation of darier disease by lithium carbonate.
Pemphigus, Benign Familial
Functional expression of heterologous proteins in yeast: insights into Ca2+ signaling and Ca2+-transporting ATPases.
Pemphigus, Benign Familial
Hailey-Hailey disease and tight junctions: Claudins 1 and 4 are regulated by ATP2C1 gene encoding Ca(2+) /Mn(2+) ATPase SPCA1 in cultured keratinocytes.
Pemphigus, Benign Familial
Hailey-Hailey disease: investigation of a possible compensatory SERCA2 up-regulation and analysis of SPCA1, p63, and IRF6 expression.
Pemphigus, Benign Familial
How do keratinizing disorders and blistering disorders overlap?
Pemphigus, Benign Familial
Human keratinocyte ATP2C1 localizes to the Golgi and controls Golgi Ca2+ stores.
Pemphigus, Benign Familial
Hypotonic, Acidic Oxidizing Solution Containing Hypochlorous Acid (HClO) as a Potential Treatment of Hailey-Hailey Disease.
Pemphigus, Benign Familial
Involucrin expression is decreased in Hailey-Hailey keratinocytes owing to increased involucrin mRNA degradation.
Pemphigus, Benign Familial
Keratinocytes cultured from patients with Hailey-Hailey disease and Darier disease display distinct patterns of calcium regulation.
Pemphigus, Benign Familial
Lithium suppresses epidermal SERCA2 and PMR1 levels in the rat.
Pemphigus, Benign Familial
Loss of the Atp2c1 secretory pathway Ca(2+)-ATPase (SPCA1) in mice causes Golgi stress, apoptosis, and midgestational death in homozygous embryos and squamous cell tumors in adult heterozygotes.
Pemphigus, Benign Familial
Mutations in ATP2C1, encoding a calcium pump, cause Hailey-Hailey disease.
Pemphigus, Benign Familial
Physiological functions of plasma membrane and intracellular Ca2+ pumps revealed by analysis of null mutants.
Pemphigus, Benign Familial
Secretory pathway stress responses as possible mechanisms of disease involving Golgi Ca2+ pump dysfunction.
Pemphigus, Benign Familial
SPCA1 governs the stability of TMEM165 in Hailey-Hailey disease.
Pemphigus, Benign Familial
SPCA1 pumps and Hailey-Hailey disease.
Pemphigus, Benign Familial
The Ca2+/Mn2+ pumps in the Golgi apparatus.
Pemphigus, Benign Familial
Transcriptional regulation of ATP2C1 gene by Sp1 and YY1 and reduced function of its promoter in Hailey-Hailey disease keratinocytes.
Pemphigus, Benign Familial
[Antidesmoglein antibodies in a patient with Hailey-Hailey disease].
Peripheral Nerve Injuries
Painful nerve injury decreases sarco-endoplasmic reticulum Ca²?-ATPase activity in axotomized sensory neurons.
Peripheral Nervous System Diseases
Recent advances in the therapy of diabetic peripheral neuropathy by means of an aldose reductase inhibitor.
Peripheral Nervous System Diseases
The slow sarco/endoplasmic reticulum Ca2+ -ATPase declines independently of slow myosin in soleus muscle of diabetic rats.
Pheochromocytoma
Anesthetic-induced alteration of Ca2+ homeostasis in neural cells: a temperature-sensitive process that is enhanced by blockade of plasma membrane Ca2+-ATPase isoforms.
Pheochromocytoma
Plasma membrane calcium ATPase plays a role in reducing Ca(2+)-mediated cytotoxicity in PC12 cells.
Pneumonia, Mycoplasma
The effect of Mycoplasma pneumoniae infection on human erythrocytes: changes in osmotic fragility, lipid composition, sialic acid content, Ca2+-ATPase activities, and ATP concentration.
Polycystic Kidney, Autosomal Dominant
Saikosaponin-d inhibits proliferation by up-regulating autophagy via the CaMKK?-AMPK-mTOR pathway in ADPKD cells.
Polymyositis
Dysfunction of the sarcoplasmic reticulum in polymyositis.
Pre-Eclampsia
Ca-ATPase Activity of Human Red Cell Ghosts: Preeclampsia, Lipid Peroxidation and MgSO(4).
Pre-Eclampsia
Ca-ATPase activity of human red cell ghosts: preeclampsia, lipid peroxidation and MgSO4.
Pre-Eclampsia
Calcium metabolism in pre-eclampsia.
Pre-Eclampsia
Calcium-ATPase activity of red blood cell ghosts from preeclamptic women, antepartum and postpartum.
Pre-Eclampsia
Changes in calcium channel proteins according to magnesium sulfate administration in placentas from pregnancies with pre-eclampsia or fetal growth restriction.
Pre-Eclampsia
Effect of magnesium sulfate on the calcium-stimulated adenosine triphosphatase activity and lipid peroxidation of red blood cell membranes from preeclamptic women.
Pre-Eclampsia
Impaired recovery of intracellular calcium and force after activation in isolated myometrial and subcutaneous resistance arteries from women with preeclampsia.
Pre-Eclampsia
Lipid peroxidation and active calcium transport in inside-out vesicles of red blood cells from preeclamptic women.
Pre-Eclampsia
Preeclampsia and calcium adenosine triphosphatase activity of red blood cell ghosts.
Pre-Eclampsia
Preeclampsia, Placenta, Oxidative Stress, and PMCA.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Blockade of Oncogenic NOTCH1 with the SERCA Inhibitor CAD204520 in T Cell Acute Lymphoblastic Leukemia.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Induction of endoplasmic reticulum calcium pump expression during early leukemic B cell differentiation.
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
The clerodane diterpene casearin J induces apoptosis of T-ALL cells through SERCA inhibition, oxidative stress, and interference with Notch1 signaling.
Premature Birth
Drug action of ritodrine on the sarcoplasmic reticulum Ca(2+)-ATPase from skeletal muscle.
Primary Graft Dysfunction
Plasma Levels of SERCA2a as a Noninvasive Biomarker of Primary Graft Dysfunction After Heart Transplantation.
Prostatic Neoplasms
Amino acid containing thapsigargin analogues deplete androgen receptor protein via synthesis inhibition and induce the death of prostate cancer cells.
Prostatic Neoplasms
Bcl-2-dependent modulation of Ca(2+) homeostasis and store-operated channels in prostate cancer cells.
Prostatic Neoplasms
Design, synthesis, and biological evaluation of hydroquinone derivatives as novel inhibitors of the sarco/endoplasmic reticulum calcium ATPase.
Prostatic Neoplasms
Design, synthesis, and pharmacological evaluation of thapsigargin analogues for targeting apoptosis to prostatic cancer cells.
Prostatic Neoplasms
Direct detection of SERCA calcium transport and small-molecule inhibition in giant unilamellar vesicles.
Prostatic Neoplasms
Expression of the Ca2+-selective cation channel TRPV6 in human prostate cancer: a novel prognostic marker for tumor progression.
Prostatic Neoplasms
Identification and characterization of a kunzeaol synthase from Thapsia garganica: Implications for the biosynthesis of the pharmaceutical thapsigargin.
Prostatic Neoplasms
Istaroxime, a potential anticancer drug in prostate cancer, exerts beneficial functional effects in healthy and diseased human myocardium.
Prostatic Neoplasms
Natural products as starting materials for development of second-generation SERCA inhibitors targeted towards prostate cancer cells.
Prostatic Neoplasms
Store depletion and store-operated Ca2+ current in human prostate cancer LNCaP cells: involvement in apoptosis.
Prostatic Neoplasms
Structure/activity Relationship of Thapsigargin Inhibition on the Purified Golgi/secretory Pathway Ca2+/Mn2+ Transport ATPase (SPCA1a).
Prostatic Neoplasms
The SERCA pump as a therapeutic target: making a "smart bomb" for prostate cancer.
Psoriasis
[Calcium-transporting system of erythrocytes in psoriasis]
Psoriasis
[Permeability for 45Ca and Ca-ATPase activity in erythrocyte membranes of patients with psoriasis]
Pulmonary Arterial Hypertension
Intra-tracheal gene delivery of aerosolized SERCA2a to the lung suppresses ventricular arrhythmias in a model of pulmonary arterial hypertension.
Pulmonary Disease, Chronic Obstructive
Abnormal sarcoplasmic reticulum Ca2+-sequestering properties in skeletal muscle in chronic obstructive pulmonary disease.
Pulmonary Disease, Chronic Obstructive
Effect of chronic obstructive pulmonary disease on calcium pump ATPase expression in human diaphragm.
Pulmonary Disease, Chronic Obstructive
[Activity of sodium-potassium adenosinetriphosphatase and cotransport of sodium, potassium and chloride ions in patients with bronchial asthma and chronic obstructive pulmonary diseases]
Pulmonary Disease, Chronic Obstructive
[Reduced expression of the sarcoplasmic calcium pump SERCA2 in skeletal muscle from patients with chronic obstructive pulmonary disease and low body weight]
Pulmonary Fibrosis
AAV1.SERCA2a Gene Therapy Reverses Pulmonary Fibrosis by Blocking the STAT3/FOXM1 Pathway and Promoting the SNON/SKI Axis.
Pulmonary Fibrosis
Lung-targeted SERCA2a Gene Therapy: From Discovery to Therapeutic Application in Bleomycin-Induced Pulmonary Fibrosis.
Pyelonephritis
[Lipid peroxidation and Ca-dependent ATPase activity in the microsomal fraction of renal tissue in patients with nephrolithiasis and chronic pyelonephritis]
Pyelonephritis
[The importance of studies of calcium reabsorption and of the capacity of the blood plasma to inhibit Ca-ATPase activity for the diagnosis of the activity of the inflammatory process and for the prognosis of tubular function in patients with chronic pyelonephritis]
Pyelonephritis
[The suppression of the Ca ATpase activity of rat kidney microsomes under the action of blood plasma as an index of the severity of the status of pyelonephritis patients]
Renal Insufficiency
A circulating inhibitor of the RBC membrane calcium pump in chronic renal failure.
Renal Insufficiency
Characterization of dimethylguanosine, phenylethylamine, and phenylacetic acid as inhibitors of Ca2+ ATPase in end-stage renal failure.
Renal Insufficiency, Chronic
Ca2+-Mg2+-dependent ATP-ase activity and calcium homeostasis in children with chronic kidney disease.
Renal Insufficiency, Chronic
The effect of vitamin D(3) supplementation on intracellular calcium and plasma membrane calcium ATPase activity in early stages of chronic kidney disease.
Reperfusion Injury
Antioxidant Network Expression Abrogates Oxidative Post-Translational Modifications in Mice.
Reperfusion Injury
Delayed phospholamban phosphorylation in post-conditioned heart favours Ca2+ normalization and contributes to protection.
Reperfusion Injury
Distribution of plasma membrane Ca2+ pump (PMCA) isoforms in the gerbil brain: effect of ischemia-reperfusion injury.
Reperfusion Injury
Effects of Compound Shenhua Tablet () on renal tubular Na(+)-K (+)-ATPase in rats with acute ischemic reperfusion injury.
Reperfusion Injury
Fasudil protects the heart against ischemia-reperfusion injury by attenuating endoplasmic reticulum stress and modulating SERCA activity: the differential role for PI3K/Akt and JAK2/STAT3 signaling pathways.
Reperfusion Injury
Generation of free radicals and the damage done to the sarcoplasmic reticulum during reperfusion injury following brief ischemia in the canine heart.
Reperfusion Injury
Injury to the Ca2+ ATPase of the sarcoplasmic reticulum in anesthetized dogs contributes to myocardial reperfusion injury.
Reperfusion Injury
Luteolin Modulates SERCA2a Leading to Attenuation of Myocardial Ischemia/ Reperfusion Injury via Sumoylation at Lysine 585 in Mice.
Reperfusion Injury
Melatonin-Induced Protective Effects on Cardiomyocytes Against Reperfusion Injury Partly Through Modulation of IP3R and SERCA2a Via Activation of ERK1.
Reperfusion Injury
Myocardial MMP-2 contributes to SERCA2a proteolysis during cardiac ischemia-reperfusion injury.
Reperfusion Injury
Role of sodium pump activity in warm induction of cardioplegia combined with reperfusion of oxygenated cardioplegic solution.
Reperfusion Injury
Secretory pathway Ca2+-ATPase isoform 1 knockdown promotes Golgi apparatus stress injury in a mouse model of focal cerebral ischemia-reperfusion: In vivo and in vitro study.
Reperfusion Injury
SERCA Overexpression Improves Mitochondrial Quality Control and Attenuates Cardiac Microvascular Ischemia-Reperfusion Injury.
Reperfusion Injury
The role of the rat sarcoplasmic reticulum Ca(2+)-ATPase promoter in myocardial ischemia-preconditioning.
Reperfusion Injury
[Effects of acupuncture at the points of the Pericardium Meridian on the activity of myocardial Ca2+-ATPase and gene expression in the rat of myocardial ischemia and reperfusion injury]
Reperfusion Injury
[Protective effect of iridoid glycosides of radix scrophulariae on endoplasmic reticulum stress induced by oxygen-glucose deprivation and reperfusion in vitro model].
Respiratory Insufficiency
SERCA pumps and human diseases.
Respiratory Insufficiency
SERCA1 attenuates diaphragm relaxation and uptake rate of SERCA in rats with acute sepsis.
Respiratory Insufficiency
Targeted disruption of the ATP2A1 gene encoding the sarco(endo)plasmic reticulum Ca2+ ATPase isoform 1 (SERCA1) impairs diaphragm function and is lethal in neonatal mice.
Respiratory Paralysis
Crotalus oreganus concolor: Envenomation Case with Venom Analysis and a Diagnostic Conundrum of Myoneurologic Symptoms.
Rhabdomyolysis
Coding sequences of sarcoplasmic reticulum calcium ATPase regulatory peptides and expression of calcium regulatory genes in recurrent exertional rhabdomyolysis.
Rhabdomyolysis
Exclusion of linkage of the RYR1, CACNA1S, and ATP2A1 genes to recurrent exertional rhabdomyolysis in Thoroughbreds.
Rhabdomyosarcoma
Chorein Sensitive Orai1 Expression and Store Operated Ca2+ Entry in Rhabdomyosarcoma Cells.
Sandhoff Disease
Inhibition of calcium uptake via the sarco/endoplasmic reticulum Ca2+-ATPase in a mouse model of Sandhoff disease and prevention by treatment with N-butyldeoxynojirimycin.
Sarcoma
Enzyme changes induced in normal and malignant tissues with chemical agents. IV. Effect of alpha-peltatin on glucose utilization by sarcoma 37 and on the adenosinetriphosphatase, hexokinase, aldolase, and pyridine nucleotide levels of sarcoma 37.
Sarcoma
[Mitochondrial adenosinetriphosphatase activity of Galliera sarcoma and of hepatic, muscular and renal tissues of bearing rats.]
Sarcoma 37
Enzyme changes induced in normal and malignant tissues with chemical agents. IV. Effect of alpha-peltatin on glucose utilization by sarcoma 37 and on the adenosinetriphosphatase, hexokinase, aldolase, and pyridine nucleotide levels of sarcoma 37.
Sarcoma, Yoshida
Inactivation of (Na-++K-+)-stimulated ATPase by a cytotoxic protein from cobra venom in relation to its lytic effects on cells.
Sarcopenia
Oxidative stress-induced dysregulation of excitation-contraction coupling contributes to muscle weakness.
Sarcopenia
Restoration of Sarcoplasmic Reticulum Ca2+ ATPase (SERCA) Activity Prevents Age-Related Muscle Atrophy and Weakness in Mice.
Seizures
A microRNA-129-5p/Rbfox crosstalk coordinates homeostatic downscaling of excitatory synapses.
Seizures
Calcium ATPase activities in synaptic plasma membranes of seizure-prone mice.
Seizures
Deficiency of a Ca2+-ATPase in brains of seizure prone mice.
Seizures
Genetic association between Ca2+-ATPase activity and audiogenic seizures in mice.
Seizures
Oxidative stress and Na,K-ATPase activity differential regulation in brainstem and forebrain of Wistar Audiogenic rats may lead to increased seizure susceptibility.
Seizures
Plasma membrane calcium ATPase plays a role in reducing Ca(2+)-mediated cytotoxicity in PC12 cells.
Seizures
Selenium and topiramate modulates brain microsomal oxidative stress values, Ca2+-ATPase activity, and EEG records in pentylentetrazol-induced seizures in rats.
Sepsis
Activation of Toll-like receptor 7 provides cardioprotection in septic cardiomyopathy-induced systolic dysfunction.
Sepsis
Altered phospholamban-calcium ATPase interaction in cardiac sarcoplasmic reticulum during the progression of sepsis.
Sepsis
Calcium uptake by sarcoplasmic reticulum is impaired during the hypodynamic phase of sepsis in the rat heart.
Sepsis
Complement and sepsis-induced heart dysfunction.
Sepsis
Complement Destabilizes Cardiomyocyte Function In Vivo after Polymicrobial Sepsis and In Vitro.
Sepsis
Erythrocyte Ca2+ pump is defective during sepsis.
Sepsis
Sepsis and burn complicated by sepsis alter cardiac transporter expression.
Sepsis
SERCA1 attenuates diaphragm relaxation and uptake rate of SERCA in rats with acute sepsis.
Sepsis
Slowed relaxation of diaphragm in septic rats is associated with reduced expression of sarco-endoplasmic reticulum Ca(2+) -ATPase genes SERCA1 and SERCA 2.
Sepsis
The synthetic antimicrobial peptide 19-2.5 attenuates septic cardiomyopathy and prevents down-regulation of SERCA2 in polymicrobial sepsis.
Sepsis
Transcriptional regulation of cardiac sarcoplasmic reticulum calcium-ATPase gene during the progression of sepsis.
Sepsis
Tumor necrosis factor-alpha decreases sarcoplasmic reticulum Ca2+-ATPase expressions via the promoter methylation in cardiomyocytes*
Sepsis
[Impaired calcium uptake by cardiac sarcoplasmic reticulum and its underlying mechanism during rat septic shock]
Sexually Transmitted Diseases
Characterization of spontaneous depolarizations in smooth muscle cells of the Guinea pig prostate.
Shock, Septic
Down-regulation of FKBP12.6 and SERCA2a contributes to acute heart failure in septic shock and is related to an up-regulated endothelin signalling pathway.
Shock, Septic
Myocardial Redox Hormesis Protects the Heart of Female Mice in Sepsis.
Shock, Septic
O-GlcNAc stimulation: A new metabolic approach to treat septic shock.
Shock, Septic
The synthetic antimicrobial peptide 19-2.5 attenuates septic cardiomyopathy and prevents down-regulation of SERCA2 in polymicrobial sepsis.
Sick Sinus Syndrome
The impact of paced QRS duration on the expression of genes related to contractile function of the left ventricle in chronically paced patients from the right ventricular apex.
Skin Diseases
Actin reorganization is abnormal and cellular ATP is decreased in Hailey-Hailey keratinocytes.
Skin Diseases
An N-terminal Ca2+-binding motif regulates the secretory pathway Ca2+/Mn2+-transport ATPase SPCA1.
Skin Diseases
Consequences of depleted SERCA2-gated calcium stores in the skin.
Skin Diseases
Darier disease is associated with heart failure: a cross-sectional case-control and population based study.
Skin Diseases
Expression of SERCA2 (Darier's disease gene product) in acantholytic dermatoses.
Skin Diseases
Expression of SPCA1 (Hailey-Hailey disease gene product) in acantholytic dermatoses.
Skin Diseases
Expression of the sarco/endoplasmic reticulum calcium ATPase type 2 and 3 isoforms in normal skin and Darier's disease.
Skin Diseases
Human keratinocyte ATP2C1 localizes to the Golgi and controls Golgi Ca2+ stores.
Skin Diseases
Involucrin expression is decreased in Hailey-Hailey keratinocytes owing to increased involucrin mRNA degradation.
Skin Diseases
Keratinocytes cultured from patients with Hailey-Hailey disease and Darier disease display distinct patterns of calcium regulation.
Skin Diseases
Metabolic phenotype in Darier disease: a cross-sectional clinical study.
Skin Diseases
Secretory pathway stress responses as possible mechanisms of disease involving Golgi Ca2+ pump dysfunction.
Skin Diseases
SERCA pumps and human diseases.
Skin Diseases
Transcriptional regulation of ATP2C1 gene by Sp1 and YY1 and reduced function of its promoter in Hailey-Hailey disease keratinocytes.
Skin Diseases, Genetic
Darier's disease: from dyskeratosis to endoplasmic reticulum calcium ATPase deficiency.
Skin Neoplasms
Intracellular calcium pool emptying induces DNA synthesis in HaCaT keratinocytes.
Skin Neoplasms
SERCA pumps and human diseases.
Small Cell Lung Carcinoma
[Effect of adenomatous polyposis coli(APC) promoter methylation on gene transcription in lung cancer cell lines]
Spherocytosis, Hereditary
[Erythrocyte membrane proteins]
Sphingolipidoses
Defective calcium homeostasis in the cerebellum in a mouse model of Niemann-Pick A disease.
Spinal Cord Injuries
Exendin-4 Plays a Protective Role in a Rat Model of Spinal Cord Injury Through SERCA2.
Spinal Cord Injuries
Pathological pain processing in mouse models of multiple sclerosis and spinal cord injury: contribution of plasma membrane calcium ATPase 2 (PMCA2).
Spinal Cord Injuries
Plasma membrane calcium ATPase deficiency causes neuronal pathology in the spinal cord: a potential mechanism for neurodegeneration in multiple sclerosis and spinal cord injury.
Spinal Cord Injuries
Plasma membrane calcium ATPase expression in the rat spinal cord.
Spinal Cord Injuries
Role of plasma membrane calcium ATPase 2 in spinal cord pathology.
Spinal Cord Injuries
Sarco(endo)plasmic reticulum calcium pump isoforms in paralyzed rat slow muscle.
Squamous Cell Carcinoma of Head and Neck
Plasma membrane Ca2+ ATPase isoform 1 down-regulated in human oral cancer.
ST Elevation Myocardial Infarction
Diabetes mellitus exacerbates post-myocardial infarction heart failure by reducing sarcolipin promoter methylation.
Starvation
Chloride channel function in the yeast TRK-potassium transporters.
Starvation
Effects of starvation on haemolymphatic glucose levels, glycogen contents and nucleotidase activities in different tissues of Helix aspersa (Müller, 1774) (Mollusca, Gastropoda).
Starvation
Effects of thyroid hormones on contractility and cation transport in skeletal muscle.
Stomach Neoplasms
Clinical significance of P-class pumps in cancer.
Stomach Neoplasms
Epigenetic regulation of the human ATP2A3 gene promoter in gastric and colon cancer cell lines.
Stomach Neoplasms
Expression of endomembrane calcium pumps in colon and gastric cancer cells. Induction of SERCA3 expression during differentiation.
Stomach Neoplasms
The calcium pump PMCA4 prevents epithelial-mesenchymal transition by inhibiting NFATc1-ZEB1 pathway in gastric cancer.
Stroke
Endothelial Progenitor Cells Modulate Inflammation-Associated Stroke Vasculome.
Stroke
G?q protein carboxyl terminus imitation polypeptide GCIP-27 improves cardiac function in chronic heart failure rats.
Stroke
Gene delivery of sarcoplasmic reticulum calcium ATPase inhibits ventricular remodeling in ischemic mitral regurgitation.
Stroke
Long-term levosimendan treatment improves systolic function and myocardial relaxation in mice with cardiomyocyte-specific disruption of the SERCA2 gene.
Stroke
Mitral regurgitation augments post-myocardial infarction remodeling failure of hypertrophic compensation.
Stroke
Multiscale Modeling of Cardiovascular Function Predicts That the End-Systolic Pressure Volume Relationship Can Be Targeted via Multiple Therapeutic Strategies.
Stroke
Pterostilbene improves cardiac function in a rat model of right heart failure through modulation of calcium handling proteins and oxidative stress.
Stroke
Selenoprotein T as a new positive inotrope in the goldfish, Carassius auratus.
Stroke
[Change in prostaglandin levels and ATPase activity of cardiac membrane fractions during the formation of cerebral hematomas in animals with a hereditary predisposition to stroke]
Tachycardia
SERCA2a was serotonylated and may regulate sino-atrial node pacemaker activity.
Tachycardia
Type 2 iodothyronin deiodinase transgene expression in the mouse heart causes cardiac-specific thyrotoxicosis.
Tachycardia
[Treatment of heart failure patients with inotropic drugs: beyond traditional agents].
Tachycardia, Ventricular
Prevention of ventricular arrhythmias with sarcoplasmic reticulum Ca2+ ATPase pump overexpression in a porcine model of ischemia reperfusion.
Tachycardia, Ventricular
Primary Effect of SERCA 2a Gene Transfer on Conduction Reserve in Chronic Myocardial Infarction.
Teratoma
Complete primary structure of a human plasma membrane Ca2+ pump.
Tetanus
Changes in the functioning of the electromechanical connection during tetanic contraction.
Tetanus
Electron probe X-ray microanalysis of post-tetanic Ca2+ and Mg2+ movements across the sarcoplasmic reticulum in situ.
Tetanus
Energetics, mechanics and molecular engineering of calcium cycling in skeletal muscle.
Tetanus
The effects of caffeine on intracellular calcium, force and the rate of relaxation of mouse skeletal muscle.
Tetanus
The steady-state force-Ca2+ relationship in intact lobster (Homarus americanus) cardiac muscle.
Tetralogy of Fallot
SERCA2a, phospholamban, sarcolipin, and ryanodine receptors gene expression in children with congenital heart defects.
Thrombosis
Modulation of vascular sarco/endoplasmic reticulum calcium ATPase in cardiovascular pathophysiology.
Thyroid Diseases
Effects of thyroid hormones on contractility and cation transport in skeletal muscle.
Thyrotoxicosis
Type 2 iodothyronin deiodinase transgene expression in the mouse heart causes cardiac-specific thyrotoxicosis.
Thyrotoxicosis
[Effect of thyroxine on the function of rabbit skeletal muscle sarcoplasmic reticulum]
Triple Negative Breast Neoplasms
A Ca2+-ATPase Regulates E-cadherin Biogenesis and Epithelial-Mesenchymal Transition in Breast Cancer Cells.
Trisomy 18 Syndrome
Cardiac expression of sarcoplasmic reticulum calcium ATPase in fetuses with trisomy 21 and trisomy 18 presenting with nuchal translucency.
Tuberculosis
Mycobacterium tuberculosis Calcium Pump CtpF Modulates the Autophagosome in an mTOR-Dependent Manner.
Urinary Bladder Neck Obstruction
Deletion of one SERCA2 allele confers protection against bladder wall hypertrophy in a murine model of partial bladder outlet obstruction.
Urinary Bladder Neck Obstruction
Persistent overexpression of SERCA2a affects bladder functions under physiological conditions, but not in bladder outlet obstruction-induced sub-acute pathological conditions.
Urinary Bladder Neoplasms
LncRNA ZNF503-AS1 acts as a tumor suppressor in bladder cancer by up-regulating Ca2+ concentration via transcription factor GATA6.
Uterine Cervical Neoplasms
SBF-1 exerts strong anticervical cancer effect through inducing endoplasmic reticulum stress-associated cell death via targeting sarco/endoplasmic reticulum Ca(2+)-ATPase 2.
Vascular Diseases
Intratracheal Gene Delivery of SERCA2a Ameliorates Chronic Post-Capillary Pulmonary Hypertension: A Large Animal Model.
Vascular Diseases
Modulation of vascular sarco/endoplasmic reticulum calcium ATPase in cardiovascular pathophysiology.
Vascular Diseases
Targeting the redox regulation of SERCA in vascular physiology and disease.
Vascular System Injuries
Therapeutic efficacy of AAV1.SERCA2a in monocrotaline-induced pulmonary arterial hypertension.
Ventricular Dysfunction
Molecular and physiological alterations in murine ventricular dysfunction.
Ventricular Dysfunction
Plasma Levels of SERCA2a as a Noninvasive Biomarker of Primary Graft Dysfunction After Heart Transplantation.
Ventricular Dysfunction, Left
Suppressed phospholamban levels differentiate irreversibly dysfunctional from hibernating myocardium in humans.
Ventricular Fibrillation
Abrupt changes in FKBP12.6 and SERCA2a expression contribute to sudden occurrence of ventricular fibrillation on reperfusion and are prevented by CPU86017.
Ventricular Fibrillation
Prevention of ventricular arrhythmias with sarcoplasmic reticulum Ca2+ ATPase pump overexpression in a porcine model of ischemia reperfusion.
Ventricular Premature Complexes
Reduced SERCA2 abundance decreases the propensity for Ca2+ wave development in ventricular myocytes.
Vesicular Stomatitis
The SPCA1 Ca(2+) pump and intracellular membrane trafficking.
Virus Diseases
Diverse Viruses Require the Calcium Transporter SPCA1 for Maturation and Spread.
Virus Diseases
Pak1 is required to maintain ventricular Ca²? homeostasis and electrophysiological stability through SERCA2a regulation in mice.
Vitamin D Deficiency
Depression of calcium pump activity in renal cortex of vitamin D-deficient rats with secondary hyperparathyroidism.
Vitamin D Deficiency
Effect of vitamin D deficiency on lipid composition and calcium transport in basolateral membrane vesicles from chick intestine.
Vitamin D Deficiency
The adenosine triphosphate-dependent calcium pump in rat small intestine: effects of vitamin D deficiency and cell isolation methods.
Vitamin E Deficiency
Ascorbic acid-Fe2+ treatment mimics effect of vitamin E deficiency on sarcoplasmic Ca-ATPase of rabbit muscle.
Vitamin E Deficiency
Change of adenosinetriphosphatase activity in the case of muscular distrophy due to vitamin E deficiency.
Vitamin E Deficiency
[PROTEIN CONTENT AND ADENOSINETRIPHOSPHATASE ACTIVITY OF MUSCLE CELLULAR ELEMENTS UNDER NORMAL CONDITIONS AND IN VITAMIN E DEFICIENCY.]
Whooping Cough
Endothelin downregulates SERCA2 gene and protein expression in adult rat ventricular myocytes: regulation by pertussis toxin-sensitive Gi protein and cAMP.
Whooping Cough
Ghrelin signalling in guinea-pig femoral artery smooth muscle cells.
Whooping Cough
Glucagon-(19-29) exerts a biphasic action on the liver plasma membrane Ca2+ pump which is mediated by G proteins.
Whooping Cough
Rapid membrane responses to dihydrotestosterone are sex dependent in growth plate chondrocytes.
Wilms Tumor
Multiplicity of cell response to the BAI strain A (myeloblastosis) avian tumor virus. VI. Ultrastructural aspects of adenosinetriphosphatase activity of nephroblastoma cells and virus.
Wolfram Syndrome
Sarco(endo)plasmic reticulum ATPase is a molecular partner of Wolfram syndrome 1 protein, which negatively regulates its expression.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
7.2.2.10 P-type Ca2+ transporter
more
top
The reliability class of the localization prediction ranges from 1 (very reliable) to 5 (not reliable). 
