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Acidosis, Lactic
Deficiency in ubiquinone cytochrome c reductase in a patient with mitochondrial myopathy and lactic acidosis.
Acidosis, Lactic
Mutations in the UQCC1-interacting protein, UQCC2, cause human complex III deficiency associated with perturbed cytochrome b protein expression.
Adenocarcinoma of Lung
Identification of ubiquinol cytochrome c reductase hinge (UQCRH) as a potential diagnostic biomarker for lung adenocarcinoma.
Altitude Sickness
Investigation of the gene co-expression network and hub genes associated with acute mountain sickness.
Alzheimer Disease
Association of gene expression and methylation of UQCRC1 to the predisposition of Alzheimer's disease in a Chinese population.
Alzheimer Disease
Brain regional analysis of NADH-cytochrome C reductase activity in Alzheimer's disease.
Alzheimer Disease
Comparative iTRAQ proteomics revealed proteins associated with spermatogenic arrest of cattleyak.
Alzheimer Disease
High-level inhibition of mitochondrial complexes III and IV is required to increase glutamate release from the nerve terminal.
Anemia
Effects of oral contraceptive steroids (norethisterone/mestranol) on the activities of hepatic drug-metabolizing enzymes in iron-deficient anemic rats.
Antley-Bixler Syndrome Phenotype
Electron transfer by human wild-type and A287P mutant P450 oxidoreductase assessed by transient kinetics: Functional Basis of P450 Oxidoreductase Deficiency.
Autoimmune Diseases
Co-expression Network Analysis Reveals Key Genes Related to Ankylosing spondylitis Arthritis Disease: Computational and Experimental Validation.
Babesiosis
Effective Therapy Targeting Cytochrome bc1 Prevents Babesia Erythrocytic Development and Protects from Lethal Infection.
Babesiosis
Targeted Structure-Activity Analysis of Endochin-like Quinolones Reveals Potent Qi and Qo Site Inhibitors of Toxoplasma gondii and Plasmodium falciparum Cytochrome bc1 and Identifies ELQ-400 as a Remarkably Effective Compound against Acute Experimental Toxoplasmosis.
Bradycardia
Coenzyme q10 confers cardiovascular protection against acute mevinphos intoxication by ameliorating bioenergetic failure and hypoxia in the rostral ventrolateral medulla of the rat.
Breast Neoplasms
Immunochemical specificity of placental NADPH cytochrome c (P-450) reductase in neoplastic and non-neoplastic human tissue.
Breast Neoplasms
Impaired OXPHOS complex III in breast cancer.
Breast Neoplasms
Therapeutic effect of propolis and paclitaxel on hepatic phase I and II enzymes and marker enzymes in dimethylbenz(a)anthracene-induced breast cancer in female rats.
Breast Neoplasms
Ubiquinol cytochrome c reductase (UQCRFS1) gene amplification in primary breast cancer core biopsy samples.
Breast Neoplasms
UQCRH gene encoding mitochondrial Hinge protein is interrupted by a translocation in a soft-tissue sarcoma and epigenetically inactivated in some cancer cell lines.
Candidiasis
Oral Microbiota Composition and Function Changes During Chronic Erythematous Candidiasis.
Carcinogenesis
Proteomic Analysis of Mitochondria-to-Nucleus Retrograde Response in Human Cancer.
Carcinogenesis
Ubiquinol-cytochrome C reductase core protein II promotes tumorigenesis by facilitating p53 degradation.
Carcinogenesis
UQCRH downregulation promotes Warburg effect in renal cell carcinoma cells.
Carcinoma
Prognostic significance of ubiquinol-cytochrome c reductase hinge protein expression in patients with clear cell renal cell carcinoma.
Carcinoma
Systematic expression analysis of the mitochondrial complex III subunits identifies UQCRC1 as biomarker in clear cell renal cell carcinoma.
Carcinoma
Tubulin Beta Chain, Filamin A Alpha Isoform 1, and Cytochrome b-c1 Complex Subunit 1 As Serological Diagnostic Biomarkers of Esophageal Squamous Cell Carcinoma: A Proteomics Study.
Carcinoma
UQCRH downregulation promotes Warburg effect in renal cell carcinoma cells.
Carcinoma, Hepatocellular
A comparison of lipids from liver and hepatoma subcellular membranes.
Carcinoma, Hepatocellular
Enhanced drug-metabolizing capacity within liver adjacent to human and rat liver tumors.
Carcinoma, Hepatocellular
Evidence that 2,3,7,8-tetrachlorodibenzo-p-dioxin induces NADPH cytochrome c (P-450) reductase in rat hepatoma cells in culture.
Carcinoma, Hepatocellular
Immunochemical specificity of placental NADPH cytochrome c (P-450) reductase in neoplastic and non-neoplastic human tissue.
Carcinoma, Hepatocellular
Import and processing of cytochrome b-c1 complex subunits in isolated hepatoma ascites cells. Inhibition by Rhodamine 6G.
Carcinoma, Hepatocellular
Nonspecific lipid transfer proteins as probes of membrane structure and function.
Carcinoma, Hepatocellular
Reactive oxygen species produced by the mitochondrial respiratory chain are involved in Cd2+-induced injury of rat ascites hepatoma AS-30D cells.
Carcinoma, Hepatocellular
The mitochondrial hinge protein, UQCRH, is a novel prognostic factor for hepatocellular carcinoma.
Carcinoma, Renal Cell
Prognostic significance of ubiquinol-cytochrome c reductase hinge protein expression in patients with clear cell renal cell carcinoma.
Carcinoma, Renal Cell
Systematic expression analysis of the mitochondrial complex III subunits identifies UQCRC1 as biomarker in clear cell renal cell carcinoma.
Carcinoma, Renal Cell
UQCRH downregulation promotes Warburg effect in renal cell carcinoma cells.
Cardiomegaly
Ubiquinol-cytochrome-c reductase 7.2 kDa protein of mitochondrial complex III is steroid-responsive and increases in cardiac hypertrophy and hypertension.
Cardiomyopathies
A missense mutation in the mitochondrial cytochrome b gene in a revisited case with histiocytoid cardiomyopathy.
Cardiomyopathies
A point mutation in the cytb gene of cardiac mtDNA associated with complex III deficiency in ischemic cardiomyopathy.
Cardiomyopathies
Myocardial energy metabolism of congestive and hypertrophic cardiomyopathy in man.
Cardiomyopathy, Hypertrophic
A mitochondrial cytochrome b mutation but no mutations of nuclearly encoded subunits in ubiquinol cytochrome c reductase (complex III) deficiency.
Cerebellar Ataxia
Nonsense mutations in CABC1/ADCK3 cause progressive cerebellar ataxia and atrophy.
Cholera
Increased aerobic glucose oxidation by cAMP in cultured regenerated skeletal myotubes.
Cholestasis
Effects of liver injury and cholestasis on microsomal enzyme activities and metabolism of halothane, enflurane and methoxyflurane in vivo in rats.
Coinfection
Coexpression of cytochrome P4502A6 and human NADPH-P450 oxidoreductase in the baculovirus system.
Colorectal Neoplasms
MiR-4435 is an UQCRB-related circulating miRNA in human colorectal cancer.
Colorectal Neoplasms
Mitochondrial UQCRB as a new molecular prognostic biomarker of human colorectal cancer.
Colorectal Neoplasms
UQCRC1 downregulation is correlated with lymph node metastasis and poor prognosis in CRC.
Communicable Diseases
2D, 3D-QSAR and molecular docking of 4(1H)-quinolones analogues with antimalarial activities.
Coronary Disease
[Ginseng prescription rules and molecular mechanism in treating coronary heart disease based on data mining and integrative pharmacology].
Cystic Fibrosis
The Km of NADH dehydrogenase is decreased in mitochondria of cystic fibrosis cells.
Cysts
New paradigms for understanding and step changes in treating active and chronic, persistent apicomplexan infections.
cytochrome-c oxidase deficiency
The extracytoplasmic function ? factor ?(C) regulates expression of a branched quinol oxidation pathway in Corynebacterium glutamicum.
Deafness
A novel mutation in BCS1L associated with deafness, tubulopathy, growth retardation and microcephaly.
Diabetes Mellitus, Type 2
The diabetes medication canagliflozin promotes mitochondrial remodelling of adipocyte via the AMPK-Sirt1-Pgc-1? signalling pathway.
Encephalomyelitis
Inhibition of brain macrophage/microglial respiratory chain enzyme activity in experimental autoimmune encephalomyelitis of the Lewis rat.
Encephalomyelitis, Autoimmune, Experimental
Inhibition of brain macrophage/microglial respiratory chain enzyme activity in experimental autoimmune encephalomyelitis of the Lewis rat.
Endotoxemia
Dysfunction of the mitochondrial respiratory chain in the rostral ventrolateral medulla during experimental endotoxemia in the rat.
Esophageal Squamous Cell Carcinoma
Tubulin Beta Chain, Filamin A Alpha Isoform 1, and Cytochrome b-c1 Complex Subunit 1 As Serological Diagnostic Biomarkers of Esophageal Squamous Cell Carcinoma: A Proteomics Study.
Fanconi Syndrome
A novel mutation in BCS1L associated with deafness, tubulopathy, growth retardation and microcephaly.
Fascioliasis
Induction of drug metabolizing enzymes in the liver of rats infested with Fasciola hepatica.
Fatty Liver
[Ginseng prescription rules and molecular mechanism in treating coronary heart disease based on data mining and integrative pharmacology].
Fetal Growth Retardation
Mutations in the UQCC1-interacting protein, UQCC2, cause human complex III deficiency associated with perturbed cytochrome b protein expression.
Genetic Diseases, Inborn
Genetic disease of mitochondrial function evaluated by NMR and NIR spectroscopy of skeletal tissue.
Glioblastoma
Downregulation of mitochondrial UQCRB inhibits cancer stem cell-like properties in glioblastoma.
Goiter
Ca(2+)/nicotinamide adenine dinucleotide phosphate-dependent H(2)O(2) generation is inhibited by iodide in human thyroids.
Goiter
Goiter and hypothyroidism in two siblings due to impaired Ca(+2)/NAD(P)H-dependent H(2)O(2)-generating activity.
Granulomatous Disease, Chronic
Delineation of the catalytic components of the NADPH-dependent O2- generating oxidoreductase of human neutrophils.
Heart Failure
Identification of Causal Genes of COVID-19 Using the SMR Method.
Hematologic Neoplasms
Double minute chromosomes in acute myeloid leukemia and myelodysplastic syndrome: identification of new amplification regions by fluorescence in situ hybridization and spectral karyotyping.
Hepatitis B
The mitochondrial hinge protein, UQCRH, is a novel prognostic factor for hepatocellular carcinoma.
Huntington Disease
High-level inhibition of mitochondrial complexes III and IV is required to increase glutamate release from the nerve terminal.
Hypertension
Ubiquinol-cytochrome-c reductase 7.2 kDa protein of mitochondrial complex III is steroid-responsive and increases in cardiac hypertrophy and hypertension.
Hyperthyroidism
Characterization of hyperthyroidism enhancement of halothane-induced hepatotoxicity.
Hyperthyroidism
Enhancement of lindane-induced liver oxidative stress and hepatotoxicity by thyroid hormone is reduced by gadolinium chloride.
Hypokinesia
[The state of the monooxygenase enzymatic system of the rat liver in hypokinesia]
Hypotension
Coenzyme q10 confers cardiovascular protection against acute mevinphos intoxication by ameliorating bioenergetic failure and hypoxia in the rostral ventrolateral medulla of the rat.
Ileus
[State of the microsomal oxidative system of the rat liver in acute intestinal obstruction]
Infections
Altered hepatic microsomal drug-metabolizing enzyme activity resulting from experimental infection of rats with Trypanosoma b. brucei.
Infections
Effective Therapy Targeting Cytochrome bc1 Prevents Babesia Erythrocytic Development and Protects from Lethal Infection.
Infections
Influenza virus-induced alterations of cytochrome P-450 enzyme activities following exposure of mice to coal and diesel particulates.
Infections
Mycoplasma pneumoniae infection induces reactive oxygen species and DNA damage in A549 human lung carcinoma cells.
Infections
New paradigms for understanding and step changes in treating active and chronic, persistent apicomplexan infections.
Infections
The ReFRAME library as a comprehensive drug repurposing library to identify mammarenavirus inhibitors.
Influenza, Human
Effect of immobilization, cold and cold-restraint stress on liver monooxygenase activity and lipid peroxidation of influenza virus-infected mice.
Iron Deficiencies
Interrelationship between iron deficiency and lead intoxication (Part 2).
Iron Deficiencies
The activity of tissue enzymes in iron-deficient rat and man: an overview.
Kidney Neoplasms
Genome-wide analysis of DNA methylation identifies the apoptosis-related gene UQCRH as a tumor suppressor in renal cancer.
Liver Diseases
Antipyrine elimination and hepatic microsomal enzyme activity in patients with liver disease.
Liver Diseases
Relationship between metabolic clearance rate of antipyrine and hepatic microsomal drug-oxidizing enzyme activities in humans without liver disease.
Liver Diseases, Alcoholic
AMPK protects against alcohol-induced liver injury through UQCRC2 to up-regulate mitophagy.
Liver Neoplasms
Hsa-miR-10a-5p downregulation in mutant UQCRB-expressing cells promotes the cholesterol biosynthesis pathway.
Lung Injury
Participation of mitochondrial respiratory complex III in neutrophil activation and lung injury.
Lymphatic Metastasis
UQCRC1 downregulation is correlated with lymph node metastasis and poor prognosis in CRC.
Lymphoma, B-Cell
Identification of collaborative activities with oxidative phosphorylation in bipolar disorder.
Malaria
2D, 3D-QSAR and molecular docking of 4(1H)-quinolones analogues with antimalarial activities.
Malaria
Acridinediones: selective and potent inhibitors of the malaria parasite mitochondrial bc1 complex.
Malaria
An exclusive computational insight toward molecular mechanism of MMV007571, a multitarget inhibitor of Plasmodium falciparum.
Malaria
Antimalarial 4(1H)-pyridones bind to the Qi site of cytochrome bc1.
Malaria
Arrested oocyst maturation in Plasmodium parasites lacking type II NADH:ubiquinone dehydrogenase.
Malaria
Atovaquone and ELQ-300 Combination Therapy as a Novel Dual-Site Cytochrome bc1 Inhibition Strategy for Malaria.
Malaria
Cytochrome b mutations that modify the ubiquinol-binding pocket of the cytochrome bc1 complex and confer anti-malarial drug resistance in Saccharomyces cerevisiae.
Malaria
Effective Therapy Targeting Cytochrome bc1 Prevents Babesia Erythrocytic Development and Protects from Lethal Infection.
Malaria
Exploring the Molecular Basis of Qo bc1 Complex Inhibitors Activity to Find Novel Antimalarials Hits.
Malaria
Exploring Ubiquinone Biosynthesis Inhibition as a Strategy for Improving Atovaquone Efficacy in Malaria.
Malaria
High-throughput virtual screening approach involving pharmacophore mapping, ADME filtering, molecular docking and MM-GBSA to identify new dual target inhibitors of PfDHODH and PfCytbc1 complex to combat drug resistant malaria.
Malaria
Inhibition of cytochrome bc1 as a strategy for single-dose, multi-stage antimalarial therapy.
Malaria
Preclinical drug metabolism and pharmacokinetic evaluation of GW844520, a novel anti-malarial mitochondrial electron transport inhibitor.
Malaria
Re-examination of inhibitor resistance conferred by Qo-site mutations in cytochrome b using yeast as a model system.
Malaria
Resistance mutations reveal the atovaquone-binding domain of cytochrome b in malaria parasites.
Malaria
Targeted Structure-Activity Analysis of Endochin-like Quinolones Reveals Potent Qi and Qo Site Inhibitors of Toxoplasma gondii and Plasmodium falciparum Cytochrome bc1 and Identifies ELQ-400 as a Remarkably Effective Compound against Acute Experimental Toxoplasmosis.
Malaria
The cytochrome bc1 complex as an antipathogenic target.
Malaria
X-ray and cryo-EM structures of inhibitor-bound cytochrome bc1 complexes for structure-based drug discovery.
Malaria
[Atovaquone/proguanil. Prophylaxis and treatment of malaria]
Melanoma
Membrane lipids and enzymes of cultured high- and low-metastatic B16 melanoma variants.
Melanoma
Proteomic investigation of the sinulariolide-treated melanoma cells A375: effects on the cell apoptosis through mitochondrial-related pathway and activation of caspase cascade.
Metabolic Syndrome
Metabolic effects of RUBCN/Rubicon deficiency in kidney proximal tubular epithelial cells.
Microcephaly
A novel mutation in BCS1L associated with deafness, tubulopathy, growth retardation and microcephaly.
Mitochondrial Diseases
Defects in the cytochrome bc1 complex in mitochondrial diseases.
Mitochondrial Diseases
Evaluating clinical mitochondrial respiratory chain enzymes from biopsy specimens presenting skewed probability distribution of activity data.
Mitochondrial Diseases
Exploiting pyocyanin to treat mitochondrial disease due to respiratory complex III dysfunction.
Mitochondrial Diseases
Hydrogen bonding rearrangement by a mitochondrial disease mutation in cytochrome bc 1 perturbs heme b H redox potential and spin state.
Mitochondrial Encephalomyopathies
Variations of activities in the segments of respiratory chain among tissues in a patient with mitochondrial encephalomyopathy.
Mitochondrial Myopathies
A new mitochondrial myopathy. Biochemical studies revealing a deficiency in the cytochrome b-c1 complex (complex III) of the respiratory chain.
Mitochondrial Myopathies
Benign mitochondrial myopathy with decreased succinate cytochrome C reductase activity.
Mitochondrial Myopathies
Decreased expression of ubiquinol-cytochrome c reductase subunits in patients exhibiting mitochondrial myopathy with progressive exercise intolerance.
Mitochondrial Myopathies
Deficiency in ubiquinone cytochrome c reductase in a patient with mitochondrial myopathy and lactic acidosis.
Mitochondrial Myopathies
Mitochondrial myopathy involving ubiquinol-cytochrome c oxidoreductase (complex III) identified by immunoelectron microscopy.
Mitochondrial Myopathies
Mitochondrial myopathy: tissue-specific expression of a defect in ubiquinol-cytochrome c reductase.
Mitochondrial Myopathies
Respiratory complex III dysfunction in humans and the use of yeast as a model organism to study mitochondrial myopathy and associated diseases.
Mitochondrial Myopathies
The cytochrome bc1 complex: function in the context of structure.
Muscular Diseases
NADH-2 cytochrome C reductase and cytochrome C oxidase in experimental muscle disorders.
Myalgia
Effects of proteome changes on the tenderness of yak rumen smooth muscle during postmortem storage based on the label-free mass spectrometry.
Myocardial Ischemia
Inhibition of myocardial rotenone-insensitive NADH cytochrome c reductase by amphiphilic compounds.
Myoglobinuria
Cytochrome c oxidase deficiency presenting as recurrent neonatal myoglobinuria.
Neoplasm Metastasis
UQCRC1 downregulation is correlated with lymph node metastasis and poor prognosis in CRC.
Neoplasms
Dehydrogenation of reduced pyridine nucleotides by Leydig cell tumors of the rat testis.
Neoplasms
Differential protein expression using proteomics from a crustacean brine shrimp (Artemia sinica) under CO2-driven seawater acidification.
Neoplasms
Downregulation of mitochondrial UQCRB inhibits cancer stem cell-like properties in glioblastoma.
Neoplasms
Dysregulation of Key Proteins Associated with Sperm Motility and Fertility Potential in Cancer Patients.
Neoplasms
Enhanced drug-metabolizing capacity within liver adjacent to human and rat liver tumors.
Neoplasms
Functional UQCRC1 polymorphisms affect promoter activity and body lipid accumulation.
Neoplasms
Genome-wide analysis of DNA methylation identifies the apoptosis-related gene UQCRH as a tumor suppressor in renal cancer.
Neoplasms
Genomic analysis in short- and long-term patients with malignant pleura mesothelioma treated with palliative chemotherapy.
Neoplasms
Identification and Validation of Novel Serum Autoantibody Biomarkers for Early Detection of Colorectal Cancer and Advanced Adenoma.
Neoplasms
Identification of collaborative activities with oxidative phosphorylation in bipolar disorder.
Neoplasms
Identification of ubiquinol cytochrome c reductase hinge (UQCRH) as a potential diagnostic biomarker for lung adenocarcinoma.
Neoplasms
Immunochemical specificity of placental NADPH cytochrome c (P-450) reductase in neoplastic and non-neoplastic human tissue.
Neoplasms
MicroRNA-661 Enhances TRAIL or STS Induced Osteosarcoma Cell Apoptosis by Modulating the Expression of Cytochrome c1.
Neoplasms
Mitochondrial Protein UQCRC1 is Oncogenic and a Potential Therapeutic Target for Pancreatic Cancer.
Neoplasms
Mitochondrial UQCRB regulates VEGFR2 signaling in endothelial cells.
Neoplasms
Proteomic Analysis of Mitochondria-to-Nucleus Retrograde Response in Human Cancer.
Neoplasms
Role of adipocyte mitochondria in inflammation, lipemia and insulin sensitivity in humans: effects of pioglitazone treatment.
Neoplasms
Superoxide generation by the respiratory chain of tumor mitochondria.
Neoplasms
Systematic expression analysis of the mitochondrial complex III subunits identifies UQCRC1 as biomarker in clear cell renal cell carcinoma.
Neoplasms
Terpestacin inhibits tumor angiogenesis by targeting UQCRB of mitochondrial complex III and suppressing hypoxia-induced reactive oxygen species production and cellular oxygen sensing.
Neoplasms
The mitochondrial hinge protein, UQCRH, is a novel prognostic factor for hepatocellular carcinoma.
Neoplasms
The Role of Dihydroorotate Dehydrogenase in Apoptosis Induction in Response to Inhibition of the Mitochondrial Respiratory Chain Complex III.
Neoplasms
The up-regulation of proteasome subunits and lysosomal proteases in hepatocellular carcinomas of the HBx gene knockin transgenic mice.
Neoplasms
Ubiquinol cytochrome c reductase (UQCRFS1) gene amplification in primary breast cancer core biopsy samples.
Neoplasms
Ubiquinol-cytochrome C reductase core protein II promotes tumorigenesis by facilitating p53 degradation.
Neoplasms
UQCRH downregulation promotes Warburg effect in renal cell carcinoma cells.
Neoplasms
UQCRH gene encoding mitochondrial Hinge protein is interrupted by a translocation in a soft-tissue sarcoma and epigenetically inactivated in some cancer cell lines.
Neoplasms
[Phenolic antioxidant TS-13 regulating ARE-dependent genes induces tumor cell death by mitochondria-dependent pathway].
Neuroblastoma
Gene expression analysis exposes mitochondrial abnormalities in a mouse model of Rett syndrome.
Non-alcoholic Fatty Liver Disease
Hepatic HuR modulates lipid homeostasis in response to high-fat diet.
Obesity
Functional UQCRC1 polymorphisms affect promoter activity and body lipid accumulation.
Obesity
Proteomic profile of visceral adipose tissues between low-fat diet-fed obesity-resistant and obesity-prone C57BL/6 mice.
Obesity, Morbid
The mtDNA 15497 G/A polymorphism in cytochrome b in severe obese subjects from Southern Italy.
Osteomyelitis
[The state of the microsomal oxidative system in the liver of rats with acute osteomyelitis of the mandible]
Osteosarcoma
Comparative proteomic analysis of osteosarcoma cell and human primary cultured osteoblastic cell.
Osteosarcoma
RNA Sequencing of Osteosarcoma Gene Expression Profile Revealed that miR-214-3p Facilitates Osteosarcoma Cell Proliferation via Targeting Ubiquinol-Cytochrome c Reductase Core Protein 1 (UQCRC1).
Ovarian Neoplasms
UQCRH gene encoding mitochondrial Hinge protein is interrupted by a translocation in a soft-tissue sarcoma and epigenetically inactivated in some cancer cell lines.
Pancreatic Neoplasms
Mitochondrial Protein UQCRC1 is Oncogenic and a Potential Therapeutic Target for Pancreatic Cancer.
Parasitemia
Inhibition of cytochrome bc1 as a strategy for single-dose, multi-stage antimalarial therapy.
Parkinson Disease
Alternative mitochondrial quality control mediated by extracellular release.
Parkinson Disease
Association mapping of the PARK10 region for Parkinson's disease susceptibility genes.
Parkinson Disease
Lack of evidence for association of UQCRC1 with autosomal dominant Parkinson's disease in Caucasian families.
Parkinson Disease
Lack of evidence for association of UQCRC1 with Parkinson's disease in Europeans.
Parkinson Disease
Mitochondrial UQCRC1 mutations cause autosomal dominant parkinsonism with polyneuropathy.
Parkinson Disease
Reply: UQCRC1 variants in Parkinson's disease: a large cohort study in Chinese mainland population.
Parkinson Disease
The lack of association between ubiquinol-cytochrome c reductase core protein I (UQCRC1) variants and Parkinson's disease in an eastern Chinese population.
Parkinson Disease
UQCRC1 variants in Parkinson's disease: a large cohort study in Chinese mainland population.
Parkinsonian Disorders
A clinical and genetic study of early-onset and familial parkinsonism in taiwan: An integrated approach combining gene dosage analysis and next-generation sequencing.
Parkinsonian Disorders
Generation of a human induced pluripotent stem cell (iPSC) line (IBMS-iPSC-057-05) from a patient with familial parkinsonism and polyneuropathy having a heterozygous p.Y314S mutation in UQCRC1 gene.
Parkinsonian Disorders
Mitochondrial UQCRC1 mutations cause autosomal dominant parkinsonism with polyneuropathy.
Peripheral Arterial Disease
Decreased NADH dehydrogenase and ubiquinol-cytochrome c oxidoreductase in peripheral arterial disease.
Peripheral Nervous System Diseases
Mitochondrial UQCRC1 mutations cause autosomal dominant parkinsonism with polyneuropathy.
Pneumonia
Circ-UQCRC2 aggravates lipopolysaccharide-induced injury in human bronchial epithelioid cells via targeting miR-495-3p/MYD88-mediated inflammatory response and oxidative stress.
Pneumonia
Identification of ubiquinol cytochrome c reductase hinge (UQCRH) as a potential diagnostic biomarker for lung adenocarcinoma.
Polyneuropathies
Generation of a human induced pluripotent stem cell (iPSC) line (IBMS-iPSC-057-05) from a patient with familial parkinsonism and polyneuropathy having a heterozygous p.Y314S mutation in UQCRC1 gene.
Polyneuropathies
Mitochondrial UQCRC1 mutations cause autosomal dominant parkinsonism with polyneuropathy.
Pulmonary Disease, Chronic Obstructive
AMPK protects against alcohol-induced liver injury through UQCRC2 to up-regulate mitophagy.
quinol-cytochrome-c reductase deficiency
Diminished Exercise Capacity and Mitochondrial bc1 Complex Deficiency in Tafazzin-Knockdown Mice.
quinol-cytochrome-c reductase deficiency
Increase in oxidative key enzymes in a case of muscle ubiquinol-cytochrome c reductase deficiency.
quinol-cytochrome-c reductase deficiency
Liver-intestine transplant from a pediatric donor with unrecognized mitochondrial succinate cytochrome C reductase deficiency.
quinol-cytochrome-c reductase deficiency
The extracytoplasmic function ? factor ?(C) regulates expression of a branched quinol oxidation pathway in Corynebacterium glutamicum.
quinol-cytochrome-c reductase deficiency
[Acute peritonitis and small bowel diverticula in a patient with mitochondrial neurogastrointestinal encephalomyopathy]
Rett Syndrome
Functional UQCRC1 polymorphisms affect promoter activity and body lipid accumulation.
Sarcoma
UQCRH gene encoding mitochondrial Hinge protein is interrupted by a translocation in a soft-tissue sarcoma and epigenetically inactivated in some cancer cell lines.
Schistosomiasis
Succinate cytochrome c reductase in schistosomiasis: in vitro inhibition by some schistosomicidal drugs.
Scrapie
The membrane location of scrapie infectivity.
Seminoma
Reduced semen quality in patients with testicular cancer seminoma is associated with alterations in the expression of sperm proteins.
Sepsis
Identification of key genes in Gram?positive and Gram?negative sepsis using stochastic perturbation.
Sjogren-Larsson Syndrome
Pre- and postnatal growth retardation, scaling skin, moderate mental retardation and quadrispasticity, hypospadias grade 2 and hydro-uretero nephrosis, postaxial polydactyly. A distinct MCA/MR syndrome?
Starvation
Cysteine starvation activates the redox-dependent mitochondrial permeability transition in retinal pigment epithelial cells.
Status Epilepticus
Mitochondrial dysfunction and ultrastructural damage in the hippocampus during kainic acid-induced status epilepticus in the rat.
Stomach Neoplasms
Identification of tubulin beta chain, thymosin beta-4-like protein 3, and cytochrome b-c1 complex subunit 1 as serological diagnostic biomarkers of gastric cancer.
Stomach Neoplasms
Modulatory effect of naringenin on N-methyl-N'-nitro-N-nitrosoguanidine- and saturated sodium chloride-induced gastric carcinogenesis in male Wistar rats.
succinate dehydrogenase deficiency
A patient with mitochondrial myopathy associated with isolated succinate dehydrogenase deficiency.
Toxoplasmosis
Targeted Structure-Activity Analysis of Endochin-like Quinolones Reveals Potent Qi and Qo Site Inhibitors of Toxoplasma gondii and Plasmodium falciparum Cytochrome bc1 and Identifies ELQ-400 as a Remarkably Effective Compound against Acute Experimental Toxoplasmosis.
Toxoplasmosis
X-ray and cryo-EM structures of inhibitor-bound cytochrome bc1 complexes for structure-based drug discovery.
Tuberculosis
3-Aryl-substituted imidazo[1,2-a]pyridines as antituberculosis agents.
Tuberculosis
Arylvinylpiperazine Amides, a New Class of Potent Inhibitors Targeting QcrB of Mycobacterium tuberculosis.
Tuberculosis
Discovery of Q203, a potent clinical candidate for the treatment of tuberculosis.
Tuberculosis
Exploiting the synthetic lethality between terminal respiratory oxidases to kill Mycobacterium tuberculosis and clear host infection.
Tuberculosis
Homology modeling and molecular docking simulation of some novel imidazo[1,2-a]pyridine-3-carboxamide (IPA) series as inhibitors of Mycobacterium tuberculosis.
Tuberculosis
Identification of 4-Amino-Thieno[2,3-d]Pyrimidines as QcrB Inhibitors in Mycobacterium tuberculosis.
Tuberculosis
Insights into Integrated Lead Generation and Target Identification in Malaria and Tuberculosis Drug Discovery.
Tuberculosis
Lansoprazole is an antituberculous prodrug targeting cytochrome bc1.
Tuberculosis
Membrane and membrane-associated proteins in Triton X-114 extracts of Mycobacterium bovis BCG identified using a combination of gel-based and gel-free fractionation strategies.
Tuberculosis
New 2-Ethylthio-4-methylaminoquinazoline derivatives inhibiting two subunits of cytochrome bc1 in Mycobacterium tuberculosis.
Tuberculosis
Nitric Oxide-Dependent Electron Transport Chain Inhibition by the Cytochrome bc1 Inhibitor and Pretomanid Combination Kills Mycobacterium tuberculosis.
Tuberculosis
No Evidence for Acquired Mutations Associated with Cytochrome bc1 Inhibitor Resistance in 13,559 Clinical Mycobacterium tuberculosis Complex Isolates.
Tuberculosis
Respiratory flexibility in response to inhibition of cytochrome C oxidase in Mycobacterium tuberculosis.
Tuberculosis
SAR and identification of 2-(quinolin-4-yloxy)acetamides as Mycobacterium tuberculosis cytochrome bc1 inhibitors.
Virus Diseases
Effect of immobilization, cold and cold-restraint stress on liver monooxygenase activity and lipid peroxidation of influenza virus-infected mice.
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7.1.1.8 quinol-cytochrome-c reductase
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The reliability class of the localization prediction ranges from 1 (very reliable) to 5 (not reliable). 
