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Information on EC 6.3.5.3 - phosphoribosylformylglycinamidine synthase

for references in articles please use BRENDA:EC6.3.5.3

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The enzyme appears in viruses and cellular organisms

Synonyms
fgam synthetase, fgams, fgar-at, fgarat, orf75c, formylglycinamide ribonucleotide amidotransferase, phosphoribosylformylglycinamidine synthase, fgar amidotransferase, smpurl, tmpurl, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
ATP + N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide + L-glutamine + H2O = ADP + phosphate + 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine + L-glutamate
show the reaction diagram
PATHWAY SOURCE
PATHWAYS
MetaCyc
5-aminoimidazole ribonucleotide biosynthesis I, 5-aminoimidazole ribonucleotide biosynthesis II, superpathway of 5-aminoimidazole ribonucleotide biosynthesis
Highest Expressing Human Cell Lines
Cell Line Links Gene Links