Any feedback?
Please rate this page
(enzyme.php)
(0/150)

BRENDA support

Information on EC 6.3.5.10 - adenosylcobyric acid synthase (glutamine-hydrolysing)

for references in articles please use BRENDA:EC6.3.5.10

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
IUBMB Comments

Requires Mg2+. NH3 can act instead of glutamine. This enzyme catalyses the four-step amidation sequence from cobyrinic acid a,c-diamide to cobyric acid via the formation of cobyrinic acid triamide, tetraamide and pentaamide intermediates.

The expected taxonomic range for this enzyme is: Archaea, Bacteria

Synonyms
cobyric acid synthase, cobyric acid synthetase, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
4 ATP + adenosylcobyrinic acid a,c-diamide + 4 L-glutamine + 4 H2O = 4 ADP + 4 phosphate + adenosylcobyric acid + 4 L-glutamate
show the reaction diagram
PATHWAY SOURCE
PATHWAYS
MetaCyc
adenosylcobinamide-GDP biosynthesis from cobyrinate a,c-diamide
Highest Expressing Human Cell Lines
Cell Line Links Gene Links