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Information on EC 6.3.5.10 - adenosylcobyric acid synthase (glutamine-hydrolysing)

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IUBMB Comments
Requires Mg2+. NH3 can act instead of glutamine. This enzyme catalyses the four-step amidation sequence from cobyrinic acid a,c-diamide to cobyric acid via the formation of cobyrinic acid triamide, tetraamide and pentaamide intermediates.
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The expected taxonomic range for this enzyme is: Bacteria, Archaea
Synonyms
cobyric acid synthase, cobyric acid synthetase, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
4 ATP + adenosylcobyrinic acid a,c-diamide + 4 L-glutamine + 4 H2O = 4 ADP + 4 phosphate + adenosylcobyric acid + 4 L-glutamate
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