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Ni-sirohydrochlorin a,c-diamide reductive cyclo-ligase (ADP-forming)
The enzyme, studied from the methanogenic archaeon Methanosarcina acetivorans, participates in the biosynthesis of the nickel-containing tetrapyrrole cofactor coenzyme F430, which is required by EC 2.8.4.1, coenzyme-B sulfoethylthiotransferase.
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ADP + phosphate + 15,173-seco-F430-173-acid + electron acceptor
ATP + Ni-sirohydrochlorin a,c-diamide + reduced electron acceptor + H2O
ATP + Ni-sirohydrochlorin a,c-diamide + reduced electron acceptor + H2O
ADP + phosphate + 15,173-seco-F430-173-acid + electron acceptor
ADP + phosphate + 15,173-seco-F430-173-acid + electron acceptor

ATP + Ni-sirohydrochlorin a,c-diamide + reduced electron acceptor + H2O
-
Substrates: -
Products: -
?
ADP + phosphate + 15,173-seco-F430-173-acid + electron acceptor
ATP + Ni-sirohydrochlorin a,c-diamide + reduced electron acceptor + H2O
-
Substrates: -
Products: -
?
ADP + phosphate + 15,173-seco-F430-173-acid + electron acceptor
ATP + Ni-sirohydrochlorin a,c-diamide + reduced electron acceptor + H2O
-
Substrates: -
Products: -
?
ADP + phosphate + 15,173-seco-F430-173-acid + electron acceptor
ATP + Ni-sirohydrochlorin a,c-diamide + reduced electron acceptor + H2O
-
Substrates: -
Products: -
?
ADP + phosphate + 15,173-seco-F430-173-acid + electron acceptor
ATP + Ni-sirohydrochlorin a,c-diamide + reduced electron acceptor + H2O
-
Substrates: -
Products: -
?
ADP + phosphate + 15,173-seco-F430-173-acid + electron acceptor
ATP + Ni-sirohydrochlorin a,c-diamide + reduced electron acceptor + H2O
-
Substrates: -
Products: -
?
ATP + Ni-sirohydrochlorin a,c-diamide + reduced electron acceptor + H2O

ADP + phosphate + 15,173-seco-F430-173-acid + electron acceptor
-
Substrates: -
Products: -
?
ATP + Ni-sirohydrochlorin a,c-diamide + reduced electron acceptor + H2O
ADP + phosphate + 15,173-seco-F430-173-acid + electron acceptor
-
Substrates: -
Products: -
?
ATP + Ni-sirohydrochlorin a,c-diamide + reduced electron acceptor + H2O
ADP + phosphate + 15,173-seco-F430-173-acid + electron acceptor
-
Substrates: -
Products: -
?
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
ADP + phosphate + 15,173-seco-F430-173-acid + electron acceptor
ATP + Ni-sirohydrochlorin a,c-diamide + reduced electron acceptor + H2O
ATP + Ni-sirohydrochlorin a,c-diamide + reduced electron acceptor + H2O
ADP + phosphate + 15,173-seco-F430-173-acid + electron acceptor
ADP + phosphate + 15,173-seco-F430-173-acid + electron acceptor

ATP + Ni-sirohydrochlorin a,c-diamide + reduced electron acceptor + H2O
-
Substrates: -
Products: -
?
ADP + phosphate + 15,173-seco-F430-173-acid + electron acceptor
ATP + Ni-sirohydrochlorin a,c-diamide + reduced electron acceptor + H2O
-
Substrates: -
Products: -
?
ADP + phosphate + 15,173-seco-F430-173-acid + electron acceptor
ATP + Ni-sirohydrochlorin a,c-diamide + reduced electron acceptor + H2O
-
Substrates: -
Products: -
?
ADP + phosphate + 15,173-seco-F430-173-acid + electron acceptor
ATP + Ni-sirohydrochlorin a,c-diamide + reduced electron acceptor + H2O
-
Substrates: -
Products: -
?
ADP + phosphate + 15,173-seco-F430-173-acid + electron acceptor
ATP + Ni-sirohydrochlorin a,c-diamide + reduced electron acceptor + H2O
-
Substrates: -
Products: -
?
ADP + phosphate + 15,173-seco-F430-173-acid + electron acceptor
ATP + Ni-sirohydrochlorin a,c-diamide + reduced electron acceptor + H2O
-
Substrates: -
Products: -
?
ATP + Ni-sirohydrochlorin a,c-diamide + reduced electron acceptor + H2O

ADP + phosphate + 15,173-seco-F430-173-acid + electron acceptor
-
Substrates: -
Products: -
?
ATP + Ni-sirohydrochlorin a,c-diamide + reduced electron acceptor + H2O
ADP + phosphate + 15,173-seco-F430-173-acid + electron acceptor
-
Substrates: -
Products: -
?
ATP + Ni-sirohydrochlorin a,c-diamide + reduced electron acceptor + H2O
ADP + phosphate + 15,173-seco-F430-173-acid + electron acceptor
-
Substrates: -
Products: -
?
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
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CFBD_METTH
Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H)
359
0
39102
Swiss-Prot
-
CFBC_METBF
Methanosarcina barkeri (strain Fusaro / DSM 804)
265
0
28578
Swiss-Prot
-
CFBD_METBF
Methanosarcina barkeri (strain Fusaro / DSM 804)
370
0
40796
Swiss-Prot
-
CFBD_METJA
Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)
352
0
39470
Swiss-Prot
-
CFBC_METAC
Methanosarcina acetivorans (strain ATCC 35395 / DSM 2834 / JCM 12185 / C2A)
265
0
28610
Swiss-Prot
-
CFBD_METAC
Methanosarcina acetivorans (strain ATCC 35395 / DSM 2834 / JCM 12185 / C2A)
370
0
40917
Swiss-Prot
-
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Pfaltz, A.; Kobelt, A.; Huester, R.; Thauer, R.
Biosynthesis of coenzyme F430 in methanogenic bacteria: Identification of 15,173-seco-F430-173-acid as an intermediate
Eur. J. Biochem.
170
459-467
1987
Methanospirillum hungatei, Methanothermobacter thermautotrophicus, Methanobrevibacter arboriphilus, Methanothermobacter thermautotrophicus DSM 2133, Methanospirillum hungatei DSM 1101, Methanobrevibacter arboriphilus DSM 744
brenda
Mucha, H.; Keller, E.; Weber, H.; Lingens, F.; Troesch, W.
Sirohydrochlorin, a precursor of factor F430 biosynthesis in Methanobacterium thermoautotrophicum
FEBS Lett.
190
169-171
1985
Methanothermobacter thermautotrophicus, Methanothermobacter thermautotrophicus DSM 1053
-
brenda
Zheng, K.; Ngo, P.; Owens, V.; Yang, X.; Mansoorabadi, S.
The biosynthetic pathway of coenzyme F430 in methanogenic and methanotrophic Archaea
Science
354
339-342
2016
Methanosarcina acetivorans
brenda
Moser, J.; Jasper, J.; Ramos, J.; Sowa, S.; Layer, G.
Expression, purification, and activity analysis of chlorophyllide oxidoreductase and Ni2+-sirohydrochlorin a,c-diamide reductase
Methods Mol. Biol.
1876
125-140
2019
Methanosarcina barkeri (Q46FL1 and Q46FL2), Methanosarcina barkeri DSM 804 (Q46FL1 and Q46FL2)
brenda
Jasper, J.; Ramos, J.; Trncik, C.; Jahn, D.; Einsle, O.; Layer, G.; Moser, J.
Chimeric interaction of nitrogenase-Like reductases with the MoFe protein of nitrogenase
ChemBioChem
21
1733-1741
2020
Methanosarcina barkeri (Q46FL1), Methanosarcina barkeri DSM 804 (Q46FL1)
brenda