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Synonyms
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ArgX
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Saci_1621
locus name
StArgX
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STK_15050
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ATP + [LysW]-C-terminal-L-glutamate + L-glutamate = ADP + phosphate + [LysW]-C-terminal-gamma-(L-glutamyl)-L-glutamate
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[LysW]-C-terminal-L-glutamate:L-glutamate ligase (ADP-forming)
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ATP + [LysW]-C-terminal-L-glutamate + L-glutamate
ADP + phosphate + [LysW]-C-terminal-gamma-(L-glutamyl)-L-glutamate
ATP + [LysW]-C-terminal-L-glutamate + L-glutamate
ADP + phosphate + [LysW]-C-terminal-gamma-(L-glutamyl)-L-glutamate
Substrates: -
?
ATP + [LysW]-C-terminal-L-glutamate + L-glutamate
ADP + phosphate + [LysW]-C-terminal-gamma-(L-glutamyl)-L-glutamate
Substrates: arginine biosynthesis. Protection of the amino group of L-glutamate by conjugation to the carrier protein LysW
?
ATP + [LysW]-C-terminal-L-glutamate + L-glutamate
ADP + phosphate + [LysW]-C-terminal-gamma-(L-glutamyl)-L-glutamate
Substrates: -
?
ATP + [LysW]-C-terminal-L-glutamate + L-glutamate
ADP + phosphate + [LysW]-C-terminal-gamma-(L-glutamyl)-L-glutamate
Substrates: arginine biosynthesis. Protection of the amino group of L-glutamate by conjugation to the carrier protein LysW
?
ATP + [LysW]-C-terminal-L-glutamate + L-glutamate
ADP + phosphate + [LysW]-C-terminal-gamma-(L-glutamyl)-L-glutamate
Substrates: -
?
ATP + [LysW]-C-terminal-L-glutamate + L-glutamate
ADP + phosphate + [LysW]-C-terminal-gamma-(L-glutamyl)-L-glutamate
Substrates: -
?
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ATP + [LysW]-C-terminal-L-glutamate + L-glutamate
ADP + phosphate + [LysW]-C-terminal-gamma-(L-glutamyl)-L-glutamate
ATP + [LysW]-C-terminal-L-glutamate + L-glutamate
ADP + phosphate + [LysW]-C-terminal-gamma-(L-glutamyl)-L-glutamate
Substrates: arginine biosynthesis. Protection of the amino group of L-glutamate by conjugation to the carrier protein LysW
?
ATP + [LysW]-C-terminal-L-glutamate + L-glutamate
ADP + phosphate + [LysW]-C-terminal-gamma-(L-glutamyl)-L-glutamate
Substrates: arginine biosynthesis. Protection of the amino group of L-glutamate by conjugation to the carrier protein LysW
?
ATP + [LysW]-C-terminal-L-glutamate + L-glutamate
ADP + phosphate + [LysW]-C-terminal-gamma-(L-glutamyl)-L-glutamate
Substrates: -
?
ATP + [LysW]-C-terminal-L-glutamate + L-glutamate
ADP + phosphate + [LysW]-C-terminal-gamma-(L-glutamyl)-L-glutamate
Substrates: -
?
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SwissProt
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SwissProt
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SwissProt
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SwissProt
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Highest Expressing Human Cell Lines
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Cell Line Links
Gene Links
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malfunction
no growth of deletion mutant without L-arginine. Growth of the deletion mutant with L-arginine supplementation is possible
malfunction
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no growth of deletion mutant without L-arginine. Growth of the deletion mutant with L-arginine supplementation is possible
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physiological function
arginine biosynthesis. Protection of the amino group of L-glutamate by conjugation to the carrier protein LysW
physiological function
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arginine biosynthesis. Protection of the amino group of L-glutamate by conjugation to the carrier protein LysW
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ARGX_SULAC
Sulfolobus acidocaldarius (strain ATCC 33909 / DSM 639 / JCM 8929 / NBRC 15157 / NCIMB 11770)
282
0
31715
Swiss-Prot
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ARGX_SULTO
Sulfurisphaera tokodaii (strain DSM 16993 / JCM 10545 / NBRC 100140 / 7)
282
0
31534
Swiss-Prot
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146000
analytical ultracentrifugation
31534
4 * 31534, calculated from sequence
31715
x * 31715, calculated from sequence
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?
x * 31715, calculated from sequence
?
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x * 31715, calculated from sequence
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tetramer
4 * 31534, calculated from sequence
tetramer
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4 * 31534, calculated from sequence
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X-ray diffraction with resolution of 1.8 A of the enzyme complexed with LysW, L-glutamate, ADP, Mg2+, Zn2+ and sulfate. X-ray diffraction with resolution of 1.87 A of the enzyme complexed with ADP
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expression in Escherichia coli
expression in Escherichia coli
expression in Escherichia coli
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Ouchi, T.; Tomita, T.; Horie, A.; Yoshida, A.; Takahashi, K.; Nishida, H.; Lassak, K.; Taka, H.; Mineki, R.; Fujimura, T.; Kosono, S.; Nishiyama, C.; Masui, R.; Kuramitsu, S.; Albers, S.V.; Kuzuyama, T.; Nishiyama, M.
Lysine and arginine biosyntheses mediated by a common carrier protein in Sulfolobus
Nat. Chem. Biol.
9
277-283
2013
Sulfolobus acidocaldarius (Q4J8E7), Sulfolobus acidocaldarius DSM 639 (Q4J8E7), Sulfurisphaera tokodaii (Q970U6), Sulfurisphaera tokodaii 7 (Q970U6)
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