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Information on EC 6.3.2.6 - phosphoribosylaminoimidazolesuccinocarboxamide synthase

for references in articles please use BRENDA:EC6.3.2.6

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IUBMB Comments

Forms part of the purine biosynthesis pathway.

The enzyme appears in viruses and cellular organisms

Synonyms
saicar synthetase, saicar synthase, phosphoribosylaminoimidazole succinocarboxamide synthetase, airc-saicars, phosphoribosylaminoimidazole-succinocarboxamide synthase, phosphoribosylaminoimidazolesuccinocarboxamide synthetase, sppurc, bapurc, phosphoribosylaminoimidazolesuccinocarboxamide synthase, phosphoribosylaminoimidazole-succinocarboxamide synthetase, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
ATP + 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate + L-aspartate = ADP + phosphate + (S)-2-[5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido]succinate
show the reaction diagram
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PATHWAY SOURCE
PATHWAYS
MetaCyc
inosine-5'-phosphate biosynthesis I, inosine-5'-phosphate biosynthesis II, inosine-5'-phosphate biosynthesis III