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Information on EC 6.3.2.59 - 3-methyl-D-ornithine---L-lysine ligase

for references in articles please use BRENDA:EC6.3.2.59

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IUBMB Comments

The enzyme participates in the biosynthesis of L-pyrrolysine, a naturally occurring, genetically coded amino acid found in some methanogenic archaea and a few bacterial species. L-pyrrolysine is present in several methyltransferases that are involved in methyl transfer from methylated amine compounds to coenzyme M.

The expected taxonomic range for this enzyme is: Methanosarcinaceae

Synonyms
atp-grasp domain-containing protein, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
ATP + (3R)-3-methyl-D-ornithine + L-lysine = ADP + phosphate + N6-[(3R)-3-methyl-D-ornithinyl]-L-lysine
show the reaction diagram
PATHWAY SOURCE
PATHWAYS
MetaCyc
L-pyrrolysine biosynthesis
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