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Cyclopeptine synthase is the key enzyme of benzodiazepine alkaloid biosynthesis in the fungus Penicillium cyclopium. The enzyme is a non-ribosomal peptide synthase.
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The enzyme appears in viruses and cellular organisms
adenylyltransferase, anthranilate, adenylyltransferase, phenylalanine, anthranilic acid adenylyltransferase, L-phenylalanine adenylyltransferase, more
2 ATP + S-adenosyl-L-methionine + anthranilate + L-phenylalanine = cyclopeptine + 2 AMP + 2 diphosphate + S-adenosyl-L-homocysteine
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