Information on EC 6.3.2.19 - ubiquitin-protein ligase and Organism(s) Homo sapiens and UniProt Accession Q00987

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UNIPROT: Q00987
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The enzyme appears in selected viruses and cellular organisms

EC NUMBER
COMMENTARY hide
6.3.2.19
deleted. The ubiquitinylation process is now known to be performed by several enzymes in sequence, starting with EC 6.2.1.45 (ubiquitin-activating enzyme E1) and followed by several transfer reactions, including those of EC 2.3.2.23 (E2 ubiquitin-conjugating enzyme) and EC 2.3.2.27 (RING-type E3 ubiquitin transferase)
RECOMMENDED NAME
GeneOntology No.
ubiquitin-protein ligase
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GENERAL INFORMATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
malfunction
metabolism
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the enzyme is involved in the ubiquitin-proteasome pathway, UPS, where it mediates the ubiquitin transfer from E2, the ubiquitin-conjugating enzyme to the lysine residue(s) of the substrate
physiological function
EXPRESSION
ORGANISM
UNIPROT
LITERATURE
Triad1 is induced on differentiation towards monocytes and granulocytes
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