Disease on EC 6.3.2.10 - UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase
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Acute Kidney Injury
Upregulation of MuRF1 and MAFbx participates to muscle wasting upon gentamicin-induced acute kidney injury.
Acute Lung Injury
A Critical Role for Muscle Ring Finger-1 in Acute Lung Injury-Associated Skeletal Muscle Wasting.
Arthritis
Eicosapentaenoic acid attenuates arthritis-induced muscle wasting acting on atrogin-1 and on myogenic regulatory factors.
Arthritis
Experimental arthritis inhibits the insulin-like growth factor-I axis and induces muscle wasting through cyclooxygenase-2 activation.
Arthritis
Ghrelin receptor agonist GHRP-2 prevents arthritis-induced increase in E3 ubiquitin-ligating enzymes MuRF1 and MAFbx gene expression in skeletal muscle.
Arthritis
Melanocortin-4 receptor agonist (RO27-3225) ameliorates soleus but not gastrocnemius atrophy in arthritic rats.
Bone Resorption
MURF1 deficiency suppresses unloading-induced effects on osteoblasts and osteoclasts to lead to bone loss.
Cardiomegaly
Cardiac muscle ring finger-1 increases susceptibility to heart failure in vivo.
Cardiomegaly
Metformin attenuates angiotensin II-induced cardiomyocyte hypertrophy by upregulating the MuRF1 and MAFbx pathway.
Cardiomegaly
MuRF1 mono-ubiquitinates TR? to inhibit T3 induced cardiac hypertrophy in vivo.
Cardiomegaly
MuRF1 Negatively Regulates Pathological Cardiac Hypertrophy Through Downregulation of Calcineurin A.
Cardiomegaly
Muscle ring finger 1 and muscle ring finger 2 are necessary but functionally redundant during developmental cardiac growth and regulate E2F1-mediated gene expression in vivo.
Cardiomegaly
Muscle ring finger 1, but not muscle ring finger 2, regulates cardiac hypertrophy in vivo.
Cardiomegaly
Muscle ring finger protein-1 inhibits PKC{epsilon} activation and prevents cardiomyocyte hypertrophy.
Cardiomegaly
Muscle RING-finger protein-1 (MuRF1) functions and cellular localization are regulated by SUMO1 post-translational modification.
Cardiomegaly
Rise above: muscle ring-finger-1 (MURF1) regulation of cardiomyocyte size and energy metabolism.
Cardiomyopathy, Hypertrophic
Muscle ring finger 1 and muscle ring finger 2 are necessary but functionally redundant during developmental cardiac growth and regulate E2F1-mediated gene expression in vivo.
Cardiomyopathy, Hypertrophic
Myosin accumulation and striated muscle myopathy result from the loss of muscle RING finger 1 and 3.
Cardiomyopathy, Hypertrophic
Rare variants in genes encoding MuRF1 and MuRF2 are modifiers of hypertrophic cardiomyopathy.
Colitis
Skeletal muscle catabolism in trinitrobenzene sulfonic acid-induced murine colitis.
Diabetic Neuropathies
[Effects of electroacupuncture on skeletal muscle and blood glucose in rats with diabetic amyotrophy].
Gastrointestinal Neoplasms
Inactivation of the ubiquitin-specific protease 19 deubiquitinating enzyme protects against muscle wasting.
Heart Failure
Cardiac muscle ring finger-1 increases susceptibility to heart failure in vivo.
Heart Failure
Heart failure increases atrogin-1 and MuRF1 gene expression in skeletal muscle with fiber type-specific atrophy.
Heart Failure
Muscle ring finger 1 and muscle ring finger 2 are necessary but functionally redundant during developmental cardiac growth and regulate E2F1-mediated gene expression in vivo.
Heart Failure
Muscle-specific regulation of right ventricular transcriptional responses to chronic hypoxia-induced hypertrophy by the muscle ring finger-1 (MuRF1) ubiquitin ligase in mice.
Hyperparathyroidism, Primary
The gene expression and activity of calpains and the muscle wasting-associated ubiquitin ligases, atrogin-1 and MuRF1, are not altered in patients with primary hyperparathyroidism.
Hypertension, Pulmonary
Expression of MuRF1 or MuRF2 is essential for the induction of skeletal muscle atrophy and dysfunction in a murine pulmonary hypertension model.
Hypertension, Pulmonary
Muscle RING finger-1 promotes a maladaptive phenotype in chronic hypoxia-induced right ventricular remodeling.
Hypertension, Pulmonary
Muscle-specific regulation of right ventricular transcriptional responses to chronic hypoxia-induced hypertrophy by the muscle ring finger-1 (MuRF1) ubiquitin ligase in mice.
Hyperthyroidism
Experimental hyperthyroidism in rats increases the expression of the ubiquitin ligases atrogin-1 and MuRF1 and stimulates multiple proteolytic pathways in skeletal muscle.
Hypertrophy, Right Ventricular
Muscle RING finger-1 promotes a maladaptive phenotype in chronic hypoxia-induced right ventricular remodeling.
Hypogonadism
Effects of a novel selective androgen receptor modulator on dexamethasone-induced and hypogonadism-induced muscle atrophy.
Infections
Pulmonary Pseudomonas aeruginosa infection induces autophagy and proteasome proteolytic pathways in skeletal muscles: effects of a pressurized whey protein-based diet in mice.
Inflammatory Bowel Diseases
Skeletal muscle catabolism in trinitrobenzene sulfonic acid-induced murine colitis.
Insulin Resistance
Fasting serum amino acids concentration is associated with insulin resistance and pro-inflammatory cytokines.
Leukemia
Preclinical Investigation of the Novel Histone Deacetylase Inhibitor AR-42 in the Treatment of Cancer-Induced Cachexia.
Lung Injury
A Critical Role for Muscle Ring Finger-1 in Acute Lung Injury-Associated Skeletal Muscle Wasting.
Lung Neoplasms
Inactivation of the ubiquitin-specific protease 19 deubiquitinating enzyme protects against muscle wasting.
Malnutrition
Fast digestive, leucine-rich, soluble milk proteins improve muscle protein anabolism, and mitochondrial function in undernourished old rats.
Melanoma
Small-Molecule Chemical Knockdown of MuRF1 in Melanoma Bearing Mice Attenuates Tumor Cachexia Associated Myopathy.
Muscular Atrophy
A CELL AUTONOMOUS ROLE FOR THE GLUCOCORTICOID RECEPTOR IN SKELETAL MUSCLE ATROPHY INDUCED BY SYSTEMIC GLUCOCORTICOID EXPOSURE.
Muscular Atrophy
A Critical Role for Muscle Ring Finger-1 in Acute Lung Injury-Associated Skeletal Muscle Wasting.
Muscular Atrophy
A new pathway encompassing calpain 3 and its newly identified substrate cardiac ankyrin repeat protein is involved in the regulation of the nuclear factor-?B pathway in skeletal muscle.
Muscular Atrophy
Activin A induces skeletal muscle catabolism via p38? mitogen-activated protein kinase.
Muscular Atrophy
ALDH2 restores exhaustive exercise-induced mitochondrial dysfunction in skeletal muscle.
Muscular Atrophy
Altered gene expression patterns in muscle ring finger 1 null mice during denervation- and dexamethasone-induced muscle atrophy.
Muscular Atrophy
Androgenic and estrogenic regulation of Atrogin-1, MuRF1 and myostatin expression in different muscle types of male mice.
Muscular Atrophy
Angiotensin II Induces Skeletal Muscle Atrophy by Activating TFEB-Mediated MuRF1 Expression.
Muscular Atrophy
Autophagy induction in atrophic muscle cells requires ULK1 activation by TRIM32 through unanchored K63-linked polyubiquitin chains.
Muscular Atrophy
Branched-chain amino acids reduce hindlimb suspension-induced muscle atrophy and protein levels of atrogin-1 and MuRF1 in rats.
Muscular Atrophy
Buyang Huanwu Tang improves denervation-dependent muscle atrophy by increasing ANGPTL4, and increases NF-?B and MURF1 levels.
Muscular Atrophy
C/EBP? regulates dexamethasone-induced muscle cell atrophy and expression of atrogin-1 and MURF1.
Muscular Atrophy
Calycosin inhibited autophagy and oxidative stress in chronic kidney disease skeletal muscle atrophy by regulating AMPK/SKP2/CARM1 signalling pathway.
Muscular Atrophy
Clenbuterol suppresses proteasomal and lysosomal proteolysis and atrophy-related genes in denervated rat soleus muscles independently of Akt.
Muscular Atrophy
Conditional activation of MET in differentiated skeletal muscle induces atrophy.
Muscular Atrophy
Conessine treatment reduces dexamethasone-induced muscle atrophy by regulating MuRF1 and atrogin-1 expression.
Muscular Atrophy
Conessine Treatment Reduces Dexamethasone-Induced Muscle Atrophy by Regulating MuRF1 and Atrogin-1 Expression.
Muscular Atrophy
Construction, Expression and Characterization of a Single Chain Variable Fragment Antibody Against Human Myostatin.
Muscular Atrophy
Daidzein alleviates cisplatin-induced muscle atrophy by regulating Glut4/AMPK/FoxO pathway.
Muscular Atrophy
De novo ceramides synthesis is not involved in skeletal muscle atrophy induced by short-term mechanical unloading.
Muscular Atrophy
Deficiency of inducible nitric oxide synthase attenuates immobilization-induced skeletal muscle atrophy in mice.
Muscular Atrophy
Deletion of atrophy enhancing genes fails to ameliorate the phenotype in a mouse model of spinal muscular atrophy.
Muscular Atrophy
Dependence of dexamethasone-induced Akt/FOXO1 signaling, upregulation of MAFbx, and protein catabolism upon the glucocorticoid receptor.
Muscular Atrophy
Dexamethasone and BCAA Failed to Modulate Muscle Mass and mTOR Signaling in GH-Deficient Rats.
Muscular Atrophy
Differential gene expression of muscle-specific ubiquitin ligase MAFbx/Atrogin-1 and MuRF1 in response to immobilization-induced atrophy of slow-twitch and fast-twitch muscles.
Muscular Atrophy
Differential skeletal muscle gene expression after upper or lower motor neuron transection.
Muscular Atrophy
Doxorubicin Exposure Causes Subacute Cardiac Atrophy Dependent on the Striated Muscle-Specific Ubiquitin Ligase MuRF1.
Muscular Atrophy
Doxorubicin Induces Inflammatory Modulation and Metabolic Dysregulation in Diabetic Skeletal Muscle.
Muscular Atrophy
Effect of dietary fish oil intake on ubiquitin ligase expression during muscle atrophy induced by sciatic nerve denervation in mice.
Muscular Atrophy
Effect of skeletal muscle phenotype and gender on fasting-induced myokine expression in mice.
Muscular Atrophy
Effects of tail suspension on serum testosterone and molecular targets regulating muscle mass.
Muscular Atrophy
Evolutionary loss of foot muscle during development with characteristics of atrophy and no evidence of cell death.
Muscular Atrophy
Exercise training has beneficial anti-atrophy effects by inhibiting oxidative stress-induced MuRF1 upregulation in rats with diabetes.
Muscular Atrophy
Exogenous insulin-like growth factor 1 attenuates cisplatin-induced muscle atrophy in mice.
Muscular Atrophy
Expression of MuRF1 or MuRF2 is essential for the induction of skeletal muscle atrophy and dysfunction in a murine pulmonary hypertension model.
Muscular Atrophy
FHL1 regulates myoblast differentiation and autophagy through its interaction with LC3.
Muscular Atrophy
FoxO3a suppression and VPS34 activity are essential to anti-atrophic effects of leucine in skeletal muscle.
Muscular Atrophy
Functional overload in ground squirrel plantaris muscle fails to induce myosin isoform shifts.
Muscular Atrophy
GHRP-2, a GHS-R agonist, directly acts on myocytes to attenuate the dexamethasone-induced expressions of muscle-specific ubiquitin ligases, Atrogin-1 and MuRF1.
Muscular Atrophy
Glucocorticoid Receptor Signaling Impairs Protein Turnover Regulation in Hypoxia-Induced Muscle Atrophy in Male Mice.
Muscular Atrophy
Glucocorticoids increase skeletal muscle NF-?B inducing kinase (NIK): links to muscle atrophy.
Muscular Atrophy
HDAC4 Knockdown Alleviates Denervation-Induced Muscle Atrophy by Inhibiting Myogenin-Dependent Atrogene Activation.
Muscular Atrophy
Heart failure increases atrogin-1 and MuRF1 gene expression in skeletal muscle with fiber type-specific atrophy.
Muscular Atrophy
High CO2 levels cause skeletal muscle atrophy via AMPK, FoxO3a and muscle-specific ring finger protein1 (MuRF1).
Muscular Atrophy
HMGB1 release and redox regulation accompany regeneration and remodeling of skeletal muscle.
Muscular Atrophy
Human skeletal muscle atrophy in amyotrophic lateral sclerosis reveals a reduction in Akt and an increase in atrogin-1.
Muscular Atrophy
Ibandronate concomitantly blocks immobilization-induced bone and muscle atrophy.
Muscular Atrophy
Identification of the MuRF1 Skeletal Muscle Ubiquitylome Through Quantitative Proteomics.
Muscular Atrophy
Identification of the optimal dose and calpain system regulation of tetramethylpyrazine on the prevention of skeletal muscle atrophy in hindlimb unloading rats.
Muscular Atrophy
Increased Expression of MuRF1 Is Associated with Radiation-induced Laryngeal Muscle Atrophy.
Muscular Atrophy
Inhibition of interleukin-6 decreases atrogene expression and ameliorates tail suspension-induced skeletal muscle atrophy.
Muscular Atrophy
Insulin Modulates Myogenesis and Muscle Atrophy Resulting From Skin Scald Burn in Young Male Rats.
Muscular Atrophy
Iron limitation promotes the atrophy of skeletal myocytes, whereas iron supplementation prevents this process in the hypoxic conditions.
Muscular Atrophy
Linalool Prevents Cisplatin Induced Muscle Atrophy by Regulating IGF-1/Akt/FoxO Pathway.
Muscular Atrophy
Long-term physical inactivity exacerbates hindlimb unloading-induced muscle atrophy in young rat soleus muscle.
Muscular Atrophy
Loquat (Eriobotrya japonica) extract prevents dexamethasone-induced muscle atrophy by inhibiting the muscle degradation pathway in Sprague Dawley rats.
Muscular Atrophy
Lung injury-induced skeletal muscle wasting in aged mice is linked to alterations in long chain fatty acid metabolism.
Muscular Atrophy
Magnesium supplementation alleviates corticosteroid-associated muscle atrophy in rats.
Muscular Atrophy
MicroRNA351 targeting TRAF6 alleviates dexamethasone-induced myotube atrophy.
Muscular Atrophy
miR-23a is decreased during muscle atrophy by a mechanism that includes calcineurin signaling and exosome-mediated export.
Muscular Atrophy
Mitochondrial dynamic remodeling in strenuous exercise-induced muscle and mitochondrial dysfunction: Regulatory effects of hydroxytyrosol.
Muscular Atrophy
Mitochondrial Dysfunction Launches Dexamethasone-Induced Skeletal Muscle Atrophy via AMPK/FOXO3 Signaling.
Muscular Atrophy
Modified expression of vitamin D receptor and CYP27B1 in denervation-induced muscle atrophy.
Muscular Atrophy
Modulation of muscle atrophy, fatigue and MLC phosphorylation by MuRF1 as indicated by hindlimb suspension studies on MuRF1-KO mice.
Muscular Atrophy
Molecular basis for the fold organization and sarcomeric targeting of the muscle atrogin MuRF1.
Muscular Atrophy
Molecular characterization of the MuRF genes in rainbow trout: Potential role in muscle degradation.
Muscular Atrophy
Mountain ginseng inhibits skeletal muscle atrophy by decreasing muscle RING ?nger protein-1 and atrogin1 through forkhead box O3 in L6 myotubes.
Muscular Atrophy
mTORC1 promotes denervation-induced muscle atrophy through a mechanism involving the activation of FoxO and E3 ubiquitin ligases.
Muscular Atrophy
Muscle atrophy and hypertrophy signaling in patients with chronic obstructive pulmonary disease.
Muscular Atrophy
Muscle proteolytic system modulation through the effect of taurine on mice bearing muscular atrophy.
Muscular Atrophy
Muscle RING-finger protein-1 (MuRF1) functions and cellular localization are regulated by SUMO1 post-translational modification.
Muscular Atrophy
Muscle Sparing in Muscle RING Finger 1 Null Mice: Response to Synthetic Glucocorticoids.
Muscular Atrophy
Muscle-specific MicroRNA1 (miR1) Targets Heat Shock Protein 70 (HSP70) during Dexamethasone-mediated Atrophy.
Muscular Atrophy
Myostatin Augments Muscle-Specific Ring Finger Protein-1 Expression Through an NF-kB Independent Mechanism in SMAD3 Null Muscle.
Muscular Atrophy
MYOSTATIN REDUCES AKT/TORC1/p70S6K SIGNALING, INHIBITING MYOBLAST DIFFERENTIATION AND MYOTUBE SIZE.
Muscular Atrophy
NF-kappaB but not FoxO sites in the MuRF1 promoter are required for transcriptional activation in disuse muscle atrophy.
Muscular Atrophy
P38?-MAPK Signaling Inhibition Attenuates Soleus Atrophy during Early Stages of Muscle Unloading.
Muscular Atrophy
Paracrine effects of IGF-1 overexpression on the functional decline due to skeletal muscle disuse: molecular and functional evaluation in hindlimb unloaded MLC/mIgf-1 transgenic mice.
Muscular Atrophy
Peroxynitrite induces degradation of myosin heavy chain via p38 MAPK and muscle-specific E3 ubiquitin ligases in C2 skeletal myotubes.
Muscular Atrophy
Physical inactivity induces the atrophy of skeletal muscle of rats through activating AMPK/FoxO3 signal pathway.
Muscular Atrophy
PPARdelta agonism induces a change in fuel metabolism and activation of an atrophy programme, but does not impair mitochondrial function in rat skeletal muscle.
Muscular Atrophy
Protective effect of branched chain amino acids on hindlimb suspension-induced muscle atrophy in growing rats.
Muscular Atrophy
Proteomic and bioinformatic analysis of differentially expressed proteins in denervated skeletal muscle.
Muscular Atrophy
Pyropia yezoensis peptide PYP1?5 protects against dexamethasone?induced muscle atrophy through the downregulation of atrogin1/MAFbx and MuRF1 in mouse C2C12 myotubes.
Muscular Atrophy
Regulation of nicotinic acetylcholine receptor turnover by MuRF1 connects muscle activity to endo/lysosomal and atrophy pathways.
Muscular Atrophy
Resistance exercise, muscle loading/unloading and the control of muscle mass.
Muscular Atrophy
Resveratrol attenuates skeletal muscle atrophy induced by chronic kidney disease via MuRF1 signaling pathway.
Muscular Atrophy
Sepsis and glucocorticoids downregulate the expression of the nuclear cofactor PGC-1beta in skeletal muscle.
Muscular Atrophy
Short-term feed deprivation rapidly induces the protein degradation pathway in skeletal muscles of young mice.
Muscular Atrophy
Skeletal Muscle Alterations Are Exacerbated in Heart Failure With Reduced Compared With Preserved Ejection Fraction: Mediated by Circulating Cytokines?
Muscular Atrophy
Skeletal Muscle Anti-Atrophic Effects of Leucine Involve Myostatin Inhibition.
Muscular Atrophy
Skeletal muscle atrophy and the E3 ubiquitin ligases MuRF1 and MAFbx/atrogin-1.
Muscular Atrophy
Skeletal muscle catabolism in trinitrobenzene sulfonic acid-induced murine colitis.
Muscular Atrophy
Skeletal muscle in MuRF1 null mice is not spared in low-gravity conditions, indicating atrophy proceeds by unique mechanisms in space.
Muscular Atrophy
Smad2/3 Proteins Are Required for Immobilization-induced Skeletal Muscle Atrophy.
Muscular Atrophy
Small-Molecule Chemical Knockdown of MuRF1 in Melanoma Bearing Mice Attenuates Tumor Cachexia Associated Myopathy.
Muscular Atrophy
Small-molecule inhibition of MuRF1 attenuates skeletal muscle atrophy and dysfunction in cardiac cachexia.
Muscular Atrophy
Suppression of atrogin-1 and MuRF1 prevents dexamethasone-induced atrophy of cultured myotubes.
Muscular Atrophy
The E3 ubiquitin ligase TRIM62 and inflammation-induced skeletal muscle atrophy.
Muscular Atrophy
The effect of vitamin D on sarcopenia depends on the level of physical activity in older adults.
Muscular Atrophy
The glucocorticoid receptor and FOXO1 synergistically activate the skeletal muscle atrophy-associated MuRF1 gene.
Muscular Atrophy
The preventive effect of ?-carotene on denervation-induced soleus muscle atrophy in mice.
Muscular Atrophy
The role and regulation of MAFbx/atrogin-1 and MuRF1 in skeletal muscle atrophy.
Muscular Atrophy
The Sympathetic Nervous System Regulates Skeletal Muscle Motor Innervation and Acetylcholine Receptor Stability.
Muscular Atrophy
TNF Receptor-Associated Factor 6 Mediates TNF?-Induced Skeletal Muscle Atrophy in Mice During Aging.
Muscular Atrophy
Transcriptional activation of muscle atrophy promotes cardiac muscle remodeling during mammalian hibernation.
Muscular Atrophy
Transnasal sphenopalatine ganglion blockade for acute facial pain: a prospective randomized case-control study.
Muscular Atrophy
Trichostatin A, a histone deacetylase inhibitor, modulates unloaded-induced skeletal muscle atrophy.
Muscular Atrophy
Tumor necrosis factor-like weak inducer of apoptosis regulates quadriceps muscle atrophy and fiber-type alteration in a rat model of chronic obstructive pulmonary disease.
Muscular Atrophy
Ubiquitylation by Trim32 causes coupled loss of desmin, Z-bands, and thin filaments in muscle atrophy.
Muscular Atrophy
Unexpected regulation pattern of the IKK?/NF-?B/MuRF1 pathway with remarkable muscle plasticity in the Daurian ground squirrel (Spermophilus dauricus).
Muscular Atrophy
Upregulation of MuRF1 and MAFbx participates to muscle wasting upon gentamicin-induced acute kidney injury.
Muscular Atrophy
WNK1 regulates skeletal muscle cell hypertrophy by modulating the nuclear localization and transcriptional activity of FOXO4.
Muscular Atrophy
[Effect of Ligustrazine on expressions of FoXO3a, MAFbx, and MuRF1 in denervated skeletal].
Muscular Atrophy
[MAFbx and MuRF1 mRNA expression and its relationship with muscular contractility following free muscle transfer]
Muscular Atrophy
[The changes of p-Akt/MuRF1/FoxO1 proteins expressions in the conditions of training and immobilization in rats' gastrocnemius muscle].
Muscular Diseases
Effects of a novel selective androgen receptor modulator on dexamethasone-induced and hypogonadism-induced muscle atrophy.
Muscular Diseases
Expression of MuRF1 or MuRF2 is essential for the induction of skeletal muscle atrophy and dysfunction in a murine pulmonary hypertension model.
Muscular Diseases
Muscle Fiber Atrophy and Regeneration Coexist in Collagen VI-Deficient Human Muscle: Role of Calpain-3 and Nuclear Factor-?B Signaling.
Muscular Diseases
Muscle RING-finger protein-1 (MuRF1) functions and cellular localization are regulated by SUMO1 post-translational modification.
Muscular Diseases
Myosin accumulation and striated muscle myopathy result from the loss of muscle RING finger 1 and 3.
Muscular Diseases
New cardiac and skeletal protein aggregate myopathy associated with combined MuRF1 and MuRF3 mutations.
Muscular Diseases
Regulation of Glucose Metabolism by MuRF1 and Treatment of Myopathy in Diabetic Mice with Small Molecules Targeting MuRF1.
Muscular Diseases
Small-Molecule Chemical Knockdown of MuRF1 in Melanoma Bearing Mice Attenuates Tumor Cachexia Associated Myopathy.
Muscular Diseases
Small-molecule-mediated chemical knock-down of MuRF1/MuRF2 and attenuation of diaphragm dysfunction in chronic heart failure.
Muscular Disorders, Atrophic
Changes in REDD1, REDD2, and atrogene mRNA expression are prevented in skeletal muscle fixed in a stretched position during hindlimb immobilization.
Muscular Disorders, Atrophic
Hsp27 inhibits IKKbeta-induced NF-kappaB activity and skeletal muscle atrophy.
Muscular Disorders, Atrophic
NF-kappaB but not FoxO sites in the MuRF1 promoter are required for transcriptional activation in disuse muscle atrophy.
Muscular Disorders, Atrophic
[Research advance on signaling pathways and protein metabolism for skeletal muscle disuse atrophy].
Myocardial Infarction
Depressed expression of MuRF1 and MAFbx in areas remote of recent myocardial infarction: a mechanism contributing to myocardial remodeling?
Neoplasms
Activation of the SDF1/CXCR4 pathway retards muscle atrophy during cancer cachexia.
Neoplasms
Caloric restriction is associated with preservation of muscle strength in experimental cancer cachexia.
Neoplasms
CALPAIN activity is increased in skeletal muscle from gastric cancer patients with no or minimal weight loss.
Neoplasms
Cryptotanshinone prevents muscle wasting in CT26-induced cancer cachexia through inhibiting STAT3 signaling pathway.
Neoplasms
Effect of dietary fish oil intake on ubiquitin ligase expression during muscle atrophy induced by sciatic nerve denervation in mice.
Neoplasms
Experimental arthritis inhibits the insulin-like growth factor-I axis and induces muscle wasting through cyclooxygenase-2 activation.
Neoplasms
Gastric cancer does not affect the expression of atrophy-related genes in human skeletal muscle.
Neoplasms
Ghrelin receptor agonist GHRP-2 prevents arthritis-induced increase in E3 ubiquitin-ligating enzymes MuRF1 and MAFbx gene expression in skeletal muscle.
Neoplasms
Imperatorin alleviates cancer cachexia and prevents muscle wasting via directly inhibiting STAT3.
Neoplasms
Inhibition of FoxO transcriptional activity prevents muscle fiber atrophy during cachexia and induces hypertrophy.
Neoplasms
Juzentaihoto Suppresses Muscle Atrophy and Decreased Motor Function in SAMP8 Mice.
Neoplasms
MG132-mediated inhibition of the ubiquitin-proteasome pathway ameliorates cancer cachexia.
Neoplasms
Molecular and cellular adaptations to exercise training in skeletal muscle from cancer patients treated with chemotherapy.
Neoplasms
Preclinical Investigation of Alpinetin in the Treatment of Cancer-Induced Cachexia via Activating PPAR?.
Neoplasms
Small-Molecule Chemical Knockdown of MuRF1 in Melanoma Bearing Mice Attenuates Tumor Cachexia Associated Myopathy.
Neoplasms
TAK-242, a specific inhibitor of Toll-like receptor 4 signalling, prevents endotoxemia-induced skeletal muscle wasting in mice.
Neoplasms
The rat model of COPD skeletal muscle dysfunction induced by progressive cigarette smoke exposure: a pilot study.
Obesity
Deterioration of mitochondrial function in the human intercostal muscles differs among individuals with sarcopenia, obesity, and sarcopenic obesity.
Osteoporosis
1?,25(OH)2D3 downregulates gene expression levels of muscle ubiquitin ligases MAFbx and MuRF1 in human myotubes.
Pancreatic Neoplasms
TRIF is a key inflammatory mediator of acute sickness behavior and cancer cachexia.
Peritonitis
Hormone, cytokine, and nutritional regulation of sepsis-induced increases in atrogin-1 and MuRF1 in skeletal muscle.
Pulmonary Disease, Chronic Obstructive
Atrophy and hypertrophy signalling of the quadriceps and diaphragm in COPD.
Pulmonary Disease, Chronic Obstructive
Involvement of the FoxO1/MuRF1/Atrogin-1 Signaling Pathway in the Oxidative Stress-Induced Atrophy of Cultured Chronic Obstructive Pulmonary Disease Myotubes.
Pulmonary Disease, Chronic Obstructive
Muscle atrophy and hypertrophy signaling in patients with chronic obstructive pulmonary disease.
Pulmonary Disease, Chronic Obstructive
Tumor necrosis factor-like weak inducer of apoptosis regulates quadriceps muscle atrophy and fiber-type alteration in a rat model of chronic obstructive pulmonary disease.
Renal Insufficiency, Chronic
Resveratrol attenuates skeletal muscle atrophy induced by chronic kidney disease via MuRF1 signaling pathway.
Reperfusion Injury
MuRF1 activity is present in cardiac mitochondria and regulates reactive oxygen species production in vivo.
Reperfusion Injury
Muscle RING finger-1 attenuates IGF-I-dependent cardiomyocyte hypertrophy by inhibiting JNK signaling.
Sarcopenia
Atrogin-1/MAFbx and MuRF1 are downregulated in aging-related loss of skeletal muscle.
Sarcopenia
Atrophy-related ubiquitin ligases, atrogin-1 and MuRF1 are up-regulated in aged rat Tibialis Anterior muscle.
Sarcopenia
Deterioration of mitochondrial function in the human intercostal muscles differs among individuals with sarcopenia, obesity, and sarcopenic obesity.
Sarcopenia
Effects of ageing on expression of the muscle-specific E3 ubiquitin ligases and Akt-dependent regulation of Foxo transcription factors in skeletal muscle.
Sarcopenia
Molecular analyses provide insight into mechanisms underlying sarcopenia and myofibre denervation in old skeletal muscles of mice.
Sciatic Neuropathy
A CELL AUTONOMOUS ROLE FOR THE GLUCOCORTICOID RECEPTOR IN SKELETAL MUSCLE ATROPHY INDUCED BY SYSTEMIC GLUCOCORTICOID EXPOSURE.
Sepsis
Inhibition of FoxO transcriptional activity prevents muscle fiber atrophy during cachexia and induces hypertrophy.
Sepsis
INHIBITION OF GSK-3? ACTIVITY WITH LITHIUM IN VITRO ATTENUATES SEPSIS-INDUCED CHANGES IN MUSCLE PROTEIN TURNOVER.
Sepsis
Marginal dietary zinc deprivation augments sepsis-induced alterations in skeletal muscle TNF-? but not protein synthesis.
Sepsis
PPAR?/? regulates glucocorticoid- and sepsis-induced FOXO1 activation and muscle wasting.
Sepsis
Sepsis and glucocorticoids downregulate the expression of the nuclear cofactor PGC-1beta in skeletal muscle.
Sepsis
Sepsis increases the expression and activity of the transcription factor Forkhead Box O 1 (FOXO1) in skeletal muscle by a glucocorticoid-dependent mechanism.
Sepsis
Sepsis upregulates the gene expression of multiple ubiquitin ligases in skeletal muscle.
Sepsis
Temporally Distinct Regulation of Pathways Contributing to Cardiac Proteostasis During the Acute and Recovery Phases of Sepsis.
Spinal Cord Injuries
(-)-Epicatechin reduces muscle waste after complete spinal cord transection in a murine model: role of ubiquitin-proteasome system.
Starvation
Ibandronate concomitantly blocks immobilization-induced bone and muscle atrophy.
Starvation
Muscle RING-finger protein-1 (MuRF1) as a connector of muscle energy metabolism and protein synthesis.
Starvation
p38 MAPK Participates in Muscle-Specific RING Finger 1-Mediated Atrophy in Cast-Immobilized Rat Gastrocnemius Muscle.
Starvation
Post-transcriptional regulation of autophagy in C2C12 myotubes following starvation and nutrient restoration.
Starvation
Proteolytic systems' expression during myogenesis and transcriptional regulation by amino acids in gilthead sea bream cultured muscle cells.
Starvation
Ubiquitin E3 ligase atrogin-1 (Fbox-32) in Atlantic salmon (Salmo salar): sequence analysis, genomic structure and modulation of expression.
Stomach Neoplasms
Gastric cancer does not affect the expression of atrophy-related genes in human skeletal muscle.
udp-n-acetylmuramoyl-tripeptide-d-alanyl-d-alanine ligase deficiency
MuRF1 deficiency prevents age-related fat weight gain, possibly through accumulation of PDK4 in skeletal muscle mitochondria in older mice.
udp-n-acetylmuramoyl-tripeptide-d-alanyl-d-alanine ligase deficiency
MURF1 deficiency suppresses unloading-induced effects on osteoblasts and osteoclasts to lead to bone loss.
Vitamin D Deficiency
The effect of vitamin D on sarcopenia depends on the level of physical activity in older adults.
Wasting Syndrome
Recent progress in elucidating signalling proteolytic pathways in muscle wasting: Potential clinical implications.
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