Disease on EC 6.3.2.1 - pantoate-beta-alanine ligase (AMP-forming)
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Altered Metabolic Flexibility in Inherited Metabolic Diseases of Mitochondrial Fatty Acid Metabolism.
5'-nucleotidase deficiency
Inborn errors of purine metabolism: clinical update and therapies.
5'-nucleotidase deficiency
Pyrimidine nucleotides impair phosphoribosylpyrophosphate (PRPP) synthetase subunit aggregation by sequestering magnesium. A mechanism for the decreased PRPP synthetase activity in hereditary erythrocyte pyrimidine 5'-nucleotidase deficiency.
6,7-dihydropteridine reductase deficiency
Differential diagnosis of tetrahydrobiopterin deficiency.
6,7-dihydropteridine reductase deficiency
Pterin metabolism in normal subjects and hyperphenylalaninaemic patients.
6,7-dihydropteridine reductase deficiency
[Trial of indirect screening of tetrahydrobiopterin deficiency]
6-phosphofructokinase deficiency
Activities of glycogen synthetase and UDPG-pyrophosphorylase in muscle of a patient with a new type of muscle glycogenosis caused by phosphofructokinase deficiency.
Abetalipoproteinemia
HARP syndrome is allelic with pantothenate kinase-associated neurodegeneration.
Abscess
Transcriptome analysis of Enterococcus faecalis during mammalian infection shows cells undergo adaptation and exist in a stringent response state.
Acidosis
Respiratory chain defect of myocardial mitochondria in idiopathic dilated cardiomyopathy of Doberman pinscher dogs.
Acidosis
[Glutathion-synthetase deficiency with 5-oxoprolinuria. Two new cases and a review of the literature (author's transl)]
Acquired Immunodeficiency Syndrome
Elevated levels of interferon-induced 2'-5' oligoadenylate synthetase in generalized persistent lymphadenopathy and the acquired immunodeficiency syndrome.
Acquired Immunodeficiency Syndrome
Interferon-induced 2'-5' oligoadenylate synthetase during interferon-alpha therapy in homosexual men with Kaposi's sarcoma: marked deficiency in biochemical response to interferon in patients with acquired immunodeficiency syndrome.
Acute Lung Injury
Cyclooxygenase and lipoxygenase inhibition by BW-755C reduces acrolein smoke-induced acute lung injury.
Acute Lung Injury
Novel insights into phosgene-induced acute lung injury in rats: role of dysregulated cardiopulmonary reflexes and nitric oxide in lung edema pathogenesis.
Acute Lung Injury
Role of poly-(ADP-ribose) synthetase in lipopolysaccharide-induced vascular failure and acute lung injury in pigs.
adenine phosphoribosyltransferase deficiency
Use of intact erythrocytes in the diagnosis of inherited purine and pyrimidine disorders.
Adenocarcinoma
Cancer-Specific Production of N-Acetylaspartate via NAT8L Overexpression in Non-Small Cell Lung Cancer and Its Potential as a Circulating Biomarker.
Adenocarcinoma
Carbamoyl phosphate synthetase (glutamine-hydrolyzing): increased activity in cancer cells.
Adenocarcinoma
Cell type-specific differences in metabolic activation of N-nitrosodiethylamine by human lung cancer cell lines.
Adenocarcinoma
Insensitivity to interferon of two subclones of human endometrial carcinoma cell line, HEC-1.
Adenocarcinoma
Resistance of cyclooxygenase-2 expressing pancreatic ductal adenocarcinoma cells against ?? T cell cytotoxicity.
Adenocarcinoma
Simplified methods for obtaining purified oocysts from mice and for growing Cryptosporidium parvum in vitro.
Adenocarcinoma
Tissue specificity for the effect of estrogen on lipogenic activity in male and female rats.
Adenocarcinoma
[The selective toxicity of 5-hydroxymethyldeoxyuridine for the cells of human adenocarcinoma of the large intestine]
Adenocarcinoma of Lung
Comparison of pyrimidine nucleotide synthetic enzymes involved in 5-fluorouracil metabolism between human adenocarcinomas and squamous cell carcinomas.
Adenocarcinoma of Lung
Nivolumab-induced anti-aminoacyl-tRNA synthetase antibody-positive polymyositis complicated by interstitial pneumonia in a patient with lung adenocarcinoma.
Adenoma
Molecular Diagnostics in the Neoplasms of the Pancreas, Liver, Gallbladder, and Extrahepatic Biliary Tract: 2018 Update.
Adenoma, Liver Cell
[Immunophenotypic classification of 3 cases of hepatocellular adenoma. Differential diagnosis with focal nodular hyperplasia].
Adenomatous Polyposis Coli
Predictive value of nuclear beta-catenin expression for the occurrence of distant metastases in rectal cancer.
Adenomatous Polyps
Aberration of poly(adenosine diphosphate-ribose) metabolism in human colon adenomatous polyps and cancers.
Adrenoleukodystrophy
Beta-oxidation of very-long-chain fatty acids and their coenzyme A derivatives by human skin fibroblasts.
Adrenoleukodystrophy
Direct demonstration that the deficient oxidation of very long chain fatty acids in X-linked adrenoleukodystrophy is due to an impaired ability of peroxisomes to activate very long chain fatty acids.
Adrenoleukodystrophy
Effects of sodium 2-[5-(4-chlorophenyl)pentyl]-oxirane-2-carboxylate (POCA) on fatty acid oxidation in fibroblasts from patients with peroxisomal diseases.
Adrenoleukodystrophy
Role of very-long-chain acyl-coenzyme A synthetase in X-linked adrenoleukodystrophy.
AIDS-Related Complex
Elevated levels of interferon-induced 2'-5' oligoadenylate synthetase in generalized persistent lymphadenopathy and the acquired immunodeficiency syndrome.
Albuminuria
Hypertensive patients exhibit an altered metabolism. A specific metabolite signature in urine is able to predict albuminuria progression.
Albuminuria
Picotamide, a dual TXB synthetase inhibitor and TXB receptor antagonist, reduces exercise-induced albuminuria in microalbuminuric patients with NIDDM.
Alopecia
Comparative evaluation between two nutritional supplements in the improvement of telogen effluvium.
Alopecia
Comparing the Effects of Zinc Sulfate, Calcium Pantothenate, Their Combination and Minoxidil Solution Regimens on Controlling Hair Loss in Women: A Randomized Controlled Trial.
Alopecia
[Evaluation of vitamin B6 and calcium pantothenate effectiveness on hair growth from clinical and trichographic aspects for treatment of diffuse alopecia in women]
Alzheimer Disease
Absence of the 40-kDa form of (2'-5')oligoadenylate synthetase and its corresponding mRNA from skin fibroblasts derived from Alzheimer disease patients.
Alzheimer Disease
Comparative study of 2',5'-oligoadenylate (2-5A) synthetase in control and Alzheimer's disease (AD) cells.
Alzheimer Disease
Neuronal plasticity and astrocytic reaction in Down syndrome and Alzheimer disease.
Alzheimer Disease
New Perspectives in Iron Chelation Therapy for the Treatment of Neurodegenerative Diseases.
Alzheimer Disease
Vitamin B5 (d-pantothenic acid) localizes in myelinated structures of the rat brain: Potential role for cerebral vitamin B5 stores in local myelin homeostasis.
Alzheimer Disease
[Effect of electroacupuncture on the expression of insulin signal pathway related proteins in hippocampus in mice with Alzheimer's disease].
amino-acid n-acetyltransferase deficiency
Improving long term outcomes in urea cycle disorders-report from the Urea Cycle Disorders Consortium.
Amyotrophic Lateral Sclerosis
Copper, Iron, and Manganese Toxicity in Neuropsychiatric Conditions.
Anaphylaxis
An inhibitor of poly(adenosine 5'-diphosphoribose) synthetase, 3-aminobenzamide, does not improve cardiovascular depression, bronchospasm, or survival associated with systemic anaphylaxis in rabbits in vivo.
Anaphylaxis
Bronchial anaphylaxis in actively sensitized Sprague Dawley rats: studies on mediators involved.
Anaphylaxis
Nitric oxide, perioxynitrite and poly(ADP-ribose) synthetase in anaphylactic shock.
Anemia
First report of co-morbidity of pantothenate kinase-associated neurodegeneration and three types of chronic hemolytic anemias.
Anemia
Heme synthesis in hereditary hemolytic anemias: decreased delta-aminolevulinic acid synthetase in hemoglobin Köln disease.
Anemia
[Glutathion-synthetase deficiency with 5-oxoprolinuria. Two new cases and a review of the literature (author's transl)]
Anemia, Hemolytic
-Glutamyl-cysteine synthetase deficiency. A cause of hereditary hemolytic anemia.
Anemia, Hemolytic, Congenital
-Glutamyl-cysteine synthetase deficiency. A cause of hereditary hemolytic anemia.
Anemia, Hypochromic
Capacity for chlorophyll synthesis in heat-bleached 70S ribosome-deficient rye leaves.
Anemia, Hypochromic
Mode of Action of the Toxin from Pseudomonas phaseolicola: I. Toxin Specificity, Chlorosis, and Ornithine Accumulation.
Anemia, Hypochromic
The Synechococcus strain PCC 7942 glnN product (glutamine synthetase III) helps recovery from prolonged nitrogen chlorosis.
Anemia, Refractory
Fusion of TEL/ETV6 to a novel ACS2 in myelodysplastic syndrome and acute myelogenous leukemia with t(5;12)(q31;p13).
Anemia, Sickle Cell
First report of co-morbidity of pantothenate kinase-associated neurodegeneration and three types of chronic hemolytic anemias.
Anemia, Sickle Cell
Heme synthesis in hereditary hemolytic anemias: decreased delta-aminolevulinic acid synthetase in hemoglobin Köln disease.
Anemia, Sideroblastic
A case of primary acquired sideroblastic anemia with deficient -aminolevulinic acid synthetase activity in bone marrow erythroblasts.
Anemia, Sideroblastic
Identification of an arginine452 to histidine substitution in the erythroid 5-aminolaevulinate synthetase gene in a large pedigree with X-linked hereditary sideroblastic anaemia.
Anemia, Sideroblastic
Linkage analysis of a large pedigree with hereditary sideroblastic anaemia.
Angina, Unstable
DTTX30, a combined thromboxane receptor antagonist and thromboxane synthetase inhibitor, prevents coronary thrombosis in anesthetized dogs.
arginase deficiency
Early liver transplantation in neonatal-onset and moderate urea cycle disorders may lead to normal neurodevelopment.
arginase deficiency
Efficacy and safety of i.v. sodium benzoate in urea cycle disorders: a multicentre retrospective study.
arginase deficiency
Improving long term outcomes in urea cycle disorders-report from the Urea Cycle Disorders Consortium.
arginine-trna ligase deficiency
Phenotypes and genotypes of mitochondrial aminoacyl-tRNA synthetase deficiencies from a single neurometabolic clinic.
argininosuccinate lyase deficiency
Improving long term outcomes in urea cycle disorders-report from the Urea Cycle Disorders Consortium.
argininosuccinate synthase deficiency
Improving long term outcomes in urea cycle disorders-report from the Urea Cycle Disorders Consortium.
Argininosuccinic Aciduria
Improving long term outcomes in urea cycle disorders-report from the Urea Cycle Disorders Consortium.
Argininosuccinic Aciduria
Urea Cycle Disorders: A Neuroimaging Pattern Approach Using Diffusion and FLAIR MRI.
Arthralgia
Oxygen-Dependent Patient with Antisynthetase Syndrome Associated Interstitial Lung Disease Responds Promptly to Rituximab with Rapid Pulmonary Function Improvement.
Arthritis
A new approach to the classification of idiopathic inflammatory myopathy: myositis-specific autoantibodies define useful homogeneous patient groups.
Arthritis
Attenuation of the progression of adjuvant-induced arthritis by 3-aminobenzamide treatment.
Arthritis
Clinical and immunogenetic features of patients with autoantibodies to asparaginyl-transfer RNA synthetase.
Arthritis
Clinical manifestations in patients with antibody to PL-12 antigen (alanyl-tRNA synthetase).
Arthritis
Clinicoserological features of antisynthetase syndrome (ASyS)-associated interstitial lung disease presenting to respiratory services: comparison with idiopathic pulmonary fibrosis and ASyS diagnosed in rheumatology services.
Arthritis
Impaired intrinsic chiral inversion activity of ibuprofen in rats with adjuvant-induced arthritis.
Arthritis
[Clinical and pathological findings of patients with interstitial lung disease associated with antisynthetase]
Arthritis
[The effect of calcium pantothenate on the adrenal cortex of patients with rheumatoid polyarthritis treated with corticosteroids]
Arthritis, Rheumatoid
A case of interstitial lung disease with anti-EJ and anti-CCP antibodies preceding rheumatoid arthritis.
Arthritis, Rheumatoid
Higher PGD2 production by synovial mast cells from rheumatoid arthritis patients compared with osteoarthritis patients via miR-199a-3p/prostaglandin synthetase 2 axis.
Arthritis, Rheumatoid
The Association of Anti-Aminoacyl-Transfer Ribonucleic Acid Synthetase Antibodies in Patients With Rheumatoid Arthritis and Interstitial Lung Disease.
Arthritis, Rheumatoid
Therapeutic advantages of the addition of calcium pantothenate to salicylates in the oral treatment of rheumatoid arthritis.
Asthma
Effect of OKY-046, a new thromboxane A2 synthetase inhibitor, on experimental asthma in guinea pigs.
Asthma
Effect of synthetase inhibitors and receptor antagonists in antigen-induced contraction of human lung parenchyma.
Asthma
Effect of thromboxane A2 synthetase inhibitor, OKY-046, on sputum in chronic bronchitis and diffuse panbronchiolitis.
Asthma
Effects of cysteinyl-leukotriene receptor antagonist, thromboxane A2 receptor antagonist, and thromboxane A2 synthetase inhibitor on antigen-induced bronchoconstriction in patients with asthma.
Asthma
Effects of inhibition of thromboxane A2 synthesis in aspirin-induced asthma.
Asthma
Glutathione ethyl ester supplementation prevents airway hyper-responsiveness in mice.
Asthma
Human bronchial epithelium controls TH2 responses by TH1-induced, nitric oxide-mediated STAT5 dephosphorylation: implications for the pathogenesis of asthma.
Asthma
Ineffectiveness of a four week treatment with the thromboxane synthetase inhibitor, imidazole salycilate, in reducing airway hyperresponsiveness to methacholine in asthmatics.
Asthma
Raised interferon ?, type 3 interferon and interferon stimulated genes - evidence of innate immune activation in neutrophilic asthma.
Asthma
The modulatory effect of antigen- and PAF-induced asthmatic reaction by aerosol administration of OKY-046 in guinea pigs.
Asthma
[Cytochemical indicators of lymphocytes after inhalation of riboflavin-nucleotide and calcium pantothenate in children with bronchial asthma]
Asthma
[Decurarization with calcium pantothenate after operations on pulmonary patients with bronchial asthma]
Asthma, Aspirin-Induced
Effects of inhibition of thromboxane A2 synthesis in aspirin-induced asthma.
Asthma, Exercise-Induced
Effect of OKY-046 (thromboxane A2 synthetase inhibitor) on exercise-induced asthma.
Astrocytoma
Participation of poly(ADP-ribose) synthetase in the process of norepinephrine-induced inhibition of major histocompatibility complex class II antigen expression in human astrocytoma cells.
Ataxia
Deep brain stimulation as a mode of treatment of early onset pantothenate kinase-associated neurodegeneration.
Ataxia
Subthalamic Nuclei Stimulation in Patients With Pantothenate Kinase-Associated Neurodegeneration (PKAN).
Atherosclerosis
Edaravone, a radical scavenger, may enhance or produce antiproliferative effects of fluvastatin, amlodipine, ozagrel, GF109203X and Y27632 on cultured basilar artery smooth muscle cells.
Atherosclerosis
Fatty acid synthesis in aorta. Isolation of fatty acid synthetase from chicken aorta.
Atherosclerosis
Lipids and cholesterol esterifying enzyme changes by Anna Pavala Sindhooram therapy in experimental rat hyperlipaemia.
Atherosclerosis
Role of inflammatory cytokines in genesis and treatment of atherosclerosis.
Atherosclerosis
The combined use of prostaglandin I2 analogue (OP-2507) and thromboxane A2 synthetase inhibitor (OKY-046) strongly inhibits atherosclerosis of aortic allografts in rats.
Autoimmune Diseases
An N,N-Bis(benzimidazolylpicolinoyl)piperazine (BT-11): A Novel Lanthionine Synthetase C-Like 2-Based Therapeutic for Inflammatory Bowel Disease.
Autoimmune Diseases
Clinical evaluation of anti-aminoacyl tRNA synthetase antibodies in Japanese patients with dermatomyositis.
Autoimmune Diseases
Correlation of Antisynthetase Antibody Levels with Disease Course in a Patient with Interstitial Lung Disease and Elevated Muscle Enzymes.
Autoimmune Pancreatitis
A case with overlapping features of IgG4-related autoimmune pancreatitis, Sjögren's syndrome and anti-aminoacyl-tRNA synthetase syndrome.
Azoospermia
Deprivation of pantothenic acid elicits a movement disorder and azoospermia in a mouse model of pantothenate kinase-associated neurodegeneration.
Bartter Syndrome
Normal prostaglandinuria E2 in Gitelman's syndrome, the hypocalciuric variant of Bartter's syndrome.
Basal Ganglia Diseases
Magnetic resonance imaging pattern recognition in childhood bilateral basal ganglia disorders.
Behcet Syndrome
Oligo-2',5'-adenylate synthetase activity in peripheral blood mononuclear leukocytes in various diseases.
Behcet Syndrome
[Investigations of interferon and oligo-2',5'-adenylate systems in endogenous uveitis]
beta-Thalassemia
Heme synthesis in hereditary hemolytic anemias: decreased delta-aminolevulinic acid synthetase in hemoglobin Köln disease.
beta-Thalassemia
Impaired erythrocyte NAD synthesis: a metabolic abnormality in thalassemia.
biotin-[propionyl-coa-carboxylase (atp-hydrolysing)] ligase deficiency
Deficiency of biotinyl-AMP synthetase activity in fibroblasts of patients with holocarboxylase synthetase deficiency.
biotin-[propionyl-coa-carboxylase (atp-hydrolysing)] ligase deficiency
[Three congenital metabolic diseases in the Faeroe Islands. Incidence, clinical and molecular genetic characteristics of Faeroese children with glycogen storage disease type IIIA, carnitine transporter deficiency and holocarboxylase synthetase deficiency]
Bone Diseases
Pharmaceutical inhibition of glycogen synthetase kinase-3? reduces multiple myeloma-induced bone disease in a novel murine plasmacytoma xenograft model.
Bone Resorption
Bimodal actions of reactive oxygen species in the differentiation and bone-resorbing functions of osteoclasts.
Brain Diseases
A comparison of interferon levels with leukocyte (2'-5') oligoadenylate synthetase activity as markers of viral encephalopathies.
Brain Diseases
Deficient activity of alanyl-tRNA synthetase underlies an autosomal recessive syndrome of progressive microcephaly, hypomyelination, and epileptic encephalopathy.
Brain Diseases
Magnetic resonance imaging pattern recognition in childhood bilateral basal ganglia disorders.
Brain Diseases
Management of status dystonicus: our experience and review of the literature.
Brain Diseases
Mitochondrial phenylalanyl-tRNA synthetase mutations underlie fatal infantile Alpers encephalopathy.
Brain Diseases
Pantothenate kinase-associated neurodegeneration in two Chinese children: identification of a novel PANK2 gene mutation.
Brain Diseases
Prospective cohort study for identification of underlying genetic causes in neonatal encephalopathy using whole-exome sequencing.
Brain Diseases
VARS2-linked mitochondrial encephalopathy: two case reports enlarging the clinical phenotype.
Brain Edema
[Cerebral edema with hyperammonemia in valpromide poisoning. Manifestation in an adult, of a partial deficit in type I carbamylphosphate synthetase]
Brain Injuries
3-Aminobenzamide, a poly (ADP-ribose) synthetase inhibitor, attenuates the acute inflammatory responses and brain injury in experimental Escherichia coli meningitis in the newborn piglet.
Brain Injuries, Traumatic
Transplantation of N -acetyl aspartyl-glutamate synthetase-activated neural stem cells after experimental traumatic brain injury significantly improves neurological recovery.
Brain Ischemia
Neuroprotective effects of inhibiting poly(ADP-ribose) synthetase on focal cerebral ischemia in rats.
Brain Neoplasms
Quantification of prostaglandin D synthetase in cerebrospinal fluid: a potential marker for brain tumor.
Breast Neoplasms
2', 5' oligo (A) synthetase levels in interferon-sensitive or resistant breast cancer cells.
Breast Neoplasms
Analysis of indoleamine 2-3 dioxygenase (IDO1) expression in breast cancer tissue by immunohistochemistry.
Breast Neoplasms
Combined the SMAC mimetic and BCL2 inhibitor sensitizes neoadjuvant chemotherapy by targeting necrosome complexes in tyrosine aminoacyl-tRNA synthase-positive breast cancer.
Breast Neoplasms
Differential effect of forms A and B of human progesterone receptor on estradiol-dependent transcription.
Breast Neoplasms
Effect of branched-chain fatty acids on fatty acid biosynthesis of human breast cancer cells.
Breast Neoplasms
Effects of progestins and menstrual cycle on fatty acid synthetase and progesterone receptor in human mammary glands.
Breast Neoplasms
Expression of the progestin-induced fatty acid synthetase in benign mastopathies and breast cancer as measured by RNA in situ hybridization.
Breast Neoplasms
Fatty acid synthetase and its mRNA are induced by progestins in breast cancer cells.
Breast Neoplasms
Her2/neu small interfering RNA delivered in culture by a streptavidin nanoparticle.
Breast Neoplasms
Hormone-regulated genes (pS2, PIP, FAS) in breast cancer and nontumoral mammary tissue.
Breast Neoplasms
Induction of 2'-5' oligoadenylate synthetase and activation of ribonuclease in tamoxifen treated human breast cancer cell lines.
Breast Neoplasms
Progestin increases gene transcription and messenger ribonucleic acid stability of fatty acid synthetase in breast cancer cells.
Breast Neoplasms
Progestin-induced fatty acid synthetase in breast cancer. From molecular biology to clinical applications.
Breast Neoplasms
Prospective study of fatty acid synthetase (FAS) expression in breast cancer and progression of disease.
Breast Neoplasms
Regulation of fatty acid synthetase ribonucleic acid in the human endometrium during the menstrual cycle.
Breast Neoplasms
The anti-progestin RU486 stabilizes the progestin-induced fatty acid synthetase mRNA but does not stimulate its transcription.
Breast Neoplasms
White button mushroom phytochemicals inhibit aromatase activity and breast cancer cell proliferation.
Breast Neoplasms
[An immunohistochemical study of aromatase, estrogen 4-hydroxylase and fatty acid synthetase in breast cancer tissues from BRCA1 mutation carriers]
Breast Neoplasms
[Effect of up-regulation of S-AdoMet synthetase on taxol-induced apoptosis in human breast cancer cells]
Breast Neoplasms
[Molecular-biological markers as prognostic factors in breast cancer of I-IIA stage]
Bronchial Spasm
An inhibitor of poly(adenosine 5'-diphosphoribose) synthetase, 3-aminobenzamide, does not improve cardiovascular depression, bronchospasm, or survival associated with systemic anaphylaxis in rabbits in vivo.
Bronchial Spasm
Effects of 1-[3-(4-benzhydryl-1-piperazinyl)propyl]-3- (1H-imidazol-1-ylmethyl)-1H-indole-6-carboxylic acid with thromboxane A2 synthetase inhibitory and H1-blocking activities on anaphylactic bronchospasm.
Bronchiolitis
Inflammatory myopathy, bronchiolitis obliterans/organizing pneumonia, and anti-Jo-1 antibodies--an interesting association.
Burkitt Lymphoma
Protein kinase C is required for induction of 2',5'-oligoadenylate synthetases.
Candidiasis
Antifungal effects of the nonlinear pharmacokinetics of cilofungin, a 1,3-beta-glucan synthetase inhibitor, during continuous and intermittent intravenous infusions in treatment of experimental disseminated candidiasis.
carbamoyl-phosphate synthase (ammonia) deficiency
Early liver transplantation in neonatal-onset and moderate urea cycle disorders may lead to normal neurodevelopment.
carbamoyl-phosphate synthase (ammonia) deficiency
Novel human pathological mutations. Gene symbol: CPS1. Disease: carbamoyl phosphate synthetase I deficiency.
Carbamoyl-Phosphate Synthase I Deficiency Disease
Continuous venovenous haemofiltration in the acute treatment of inborn errors of metabolism.
Carbamoyl-Phosphate Synthase I Deficiency Disease
Metabolic stroke in carbamyl phosphate synthetase deficiency.
Carbamoyl-Phosphate Synthase I Deficiency Disease
Novel human pathological mutations. Gene symbol: CPS1. Disease: carbamoyl phosphate synthetase I deficiency.
Carcinogenesis
A novel human tRNA-dihydrouridine synthase involved in pulmonary carcinogenesis.
Carcinogenesis
Association of promoter polymorphism -765G>C in the PTGS2 gene with malignant melanoma in Italian patients and its correlation to gene expression in dermal fibroblasts.
Carcinogenesis
Beta-catenin mutations are frequent in hepatocellular carcinomas but absent in adenomas induced by diethylnitrosamine in B6C3F1 mice.
Carcinogenesis
Cyclin D1 over-expression correlates with beta-catenin activation, but not with H-ras mutations, and phosphorylation of Akt, GSK3 beta and ERK1/2 in mouse hepatic carcinogenesis.
Carcinogenesis
Do NSAIDs exert their colon cancer chemoprevention activities through the inhibition of mucosal prostaglandin synthetase?
Carcinogenesis
Fatty acid synthetase and its mRNA are induced by progestins in breast cancer cells.
Carcinogenesis
Resistance of cyclooxygenase-2 expressing pancreatic ductal adenocarcinoma cells against ?? T cell cytotoxicity.
Carcinogenesis
Studies of carcinogenesis by avian sarcoma viruses. II. Virus-induced increase in hyaluronic acid synthetase in chicken fibroblasts.
Carcinogenesis
[Mechanism of carcinogenesis. VII. Biosynthesis of carbamyl phosphate synthetase I in vivo and in vitro in hepatocellular carcinoma and liver of rats fed with diethylnitrosamine]
Carcinoma
Cancer-Specific Production of N-Acetylaspartate via NAT8L Overexpression in Non-Small Cell Lung Cancer and Its Potential as a Circulating Biomarker.
Carcinoma
Combined therapy with cisplatin and interferon alpha-2b (INTRON-A) in patients with penile carcinoma. Analysis of 2'5' oligo (A) synthetase and circulating interferon.
Carcinoma
Comparison of pyrimidine nucleotide synthetic enzymes involved in 5-fluorouracil metabolism between human adenocarcinomas and squamous cell carcinomas.
Carcinoma
Development of a chemoresistant orthotopic human nonsmall cell lung carcinoma model in nude mice: analyses of tumor heterogenity in relation to the immunohistochemical levels of expression of cyclooxygenase-2, ornithine decarboxylase, lung-related resistance protein, prostaglandin E synthetase, and glutathione-S-transferase-alpha (GST)-alpha, GST-mu, and GST-pi.
Carcinoma
FLUORINATED PYRIMIDINES. XXV. THE INHIBITION OF THYMIDYLATE SYNTHETASE FROM EHRLICH ASCITES CARCINOMA CELLS BY PYRIMIDINE ANALOGS.
Carcinoma
Glucosylceramide synthetase inhibitor, D-threo-1-phenyl-2-decanoylamino-3-morpholino-1-propanol exhibits a novel decarcinogenic activity against Shope carcinoma cells.
Carcinoma
Heme regulation in mouse mammary carcinoma and liver of tumor bearing mice--I. Effect of allyl-isopropylacetamide and veronal on delta-aminolevulinate synthetase, cytochrome P-450 and cytochrome oxidase.
Carcinoma
Histochemical studies of glycogen metabolizing enzymes in normal and abnormal human cervical epithelium.
Carcinoma
Hormonal and immunological regulation of 2', 5'-oligoadenylate synthetase activity in human peripheral blood mononuclear cells.
Carcinoma
Hormone dependency of carcinoma of the human endometrium. Effect of progesterone on glycogen metabolism in the carcinoma tissue.
Carcinoma
Inactivation by acivicin of carbamoyl-phosphate synthetase II of human colon carcinoma.
Carcinoma
Initial steps in pyrimidine synthesis in Ehrlich ascites carcinoma in vitro. II. The synthesis of carbamyl phosphate by a soluble, glutamine-dependent carbamyl phosphate synthetase.
Carcinoma
Monitoring of interferon treatment in patients with renal cell carcinoma and bladder carcinoma by oligo-A synthetase assay and determination of immunological parameters.
Carcinoma
Proliferation-linked increase in phosphoribosylformylglycinamidine synthetase activity (EC 6.3.5.3).
Carcinoma
Study of 2'5' oligo (A) synthetase in patients with metastatic renal cell carcinoma.
Carcinoma
The effects of pH and inhibitors upon the catalytic activity of the dihydroorotase of multienzymatic protein pyr1-3 from mouse Ehrlich ascites carcinoma.
Carcinoma
The modification of ferroptosis and abnormal lipometabolism through overexpression and knockdown of potential prognostic biomarker perilipin2 in gastric carcinoma.
Carcinoma
Using Q-RT-PCR to measure cyclin D1, TS, TP, DPD, and Her-2/neu as predictors for response, survival, and recurrence in patients with esophageal squamous cell carcinoma following radiochemotherapy.
Carcinoma
[Mechanism of carcinogenesis. VII. Biosynthesis of carbamyl phosphate synthetase I in vivo and in vitro in hepatocellular carcinoma and liver of rats fed with diethylnitrosamine]
Carcinoma in Situ
Histochemical studies of glycogen metabolizing enzymes in normal and abnormal human cervical epithelium.
Carcinoma, Ehrlich Tumor
5-Phosphoribosyl pyrophosphate synthetase from Ehrlich ascites tumor cells.
Carcinoma, Ehrlich Tumor
DNA fragmentation and NAD depletion. Their relation to the turnover of endogenous mono(ADP-ribosyl) and poly(ADP-ribosyl) proteins.
Carcinoma, Ehrlich Tumor
Induction of 2',5'oligo (A) synthetase in animals bearing Ehrlich ascites tumor cells.
Carcinoma, Ehrlich Tumor
Inhibition of the phosphoribosyl-formylglycineamidine synthetase of Ehrlich ascites tumor cells by glutamine analogues.
Carcinoma, Ehrlich Tumor
Interferon, double-stranded RNA, and RNA degradation. Isolation of homogeneous pppA(2'p5'A)n-1 synthetase from Ehrlich ascites tumor cells.
Carcinoma, Ehrlich Tumor
Interferons, double-stranded RNA, and RNA degradation. Isolation and characterization of homogeneous human (2'-5')(a)n synthetase.
Carcinoma, Ehrlich Tumor
Purification and properties of phosphoribosyl-formylglycineamidine synthetase of ehrlich ascites tumor cells.
Carcinoma, Ehrlich Tumor
Studies on the activities of some methyltransferases in the livers and tumor cells from tumor-bearing mice.
Carcinoma, Ehrlich Tumor
Studies with pure mouse Ehrlich ascites tumor interferons alpha and beta: patterns of induction of (2'-5') (A)n synthetase and of a double-stranded RNA-dependent protein kinase in mouse cells and human cells.
Carcinoma, Ehrlich Tumor
Synthesis of (2'-5')(A)n from ATP. Characteristics of the reaction catalyzed by (2'-5')(A)n synthetase purified from mouse Ehrlich ascites tumor cells treated with interferon.
Carcinoma, Embryonal
Action of murine gamma (immune)interferon on beta (fibroblast)-interferon resistant L 1210 and embryonal carcinoma cells.
Carcinoma, Hepatocellular
3-Aminobenzamide inhibits poly(ADP ribose) synthetase activity and induces phosphoenolpyruvate carboxykinase (GTP) in H4IIE hepatoma cells.
Carcinoma, Hepatocellular
?-Glutamylcysteine synthetase (?-GCS) as a target for overcoming chemo- and radio-resistance of human hepatocellular carcinoma cells.
Carcinoma, Hepatocellular
Activities of enzymes of lipid metabolism in Morris hepatoma 7800 C1 cells.
Carcinoma, Hepatocellular
Activities of key gluconeogenic enzymes and glycogen synthase in rat and human livers, hepatomas, and hepatoma cell cultures.
Carcinoma, Hepatocellular
Characterization of cystathionine synthase as a selectable, liver-specific trait in rat hepatomas.
Carcinoma, Hepatocellular
Differences in total mitochondrial proteins and proteins synthesized by mitochondria from rat liver and Morris hepatomas 9618A, 5123C, and 5123tc.
Carcinoma, Hepatocellular
Disparity in the effects of two N-methyl nicotinamides on poly(ADP-ribose) synthetase and macromolecular synthesis in hepatomas.
Carcinoma, Hepatocellular
Enhancement of glutathione and g-glutamylcysteine synthetase, the rate limiting enzyme of glutathione synthesis, by chemoprotective plant-derived food and beverage components in the human hepatoma cell line HepG2.
Carcinoma, Hepatocellular
Glycogen synthesis and glycogen synthetase in rat ascites hepatomas of low and high glycogen content.
Carcinoma, Hepatocellular
Glycogen synthesis and I to D conversion of glycogen synthetase in ascites hepatoma cells.
Carcinoma, Hepatocellular
Glycogen synthetase of rat skeletal muscle and hepatomas and its comparison with the enzyme of rat liver.
Carcinoma, Hepatocellular
Guanosine-5'-phosphate synthetase and guanosine-5'-phosphate kinase in rat hepatomas and kidney tumors.
Carcinoma, Hepatocellular
In vivo inactivation by acivicin of carbamoyl-phosphate synthetase II in rat hepatoma.
Carcinoma, Hepatocellular
In vivo inactivation of formylglycinamidine ribonucleotide synthetase in rat hepatoma.
Carcinoma, Hepatocellular
Increased 5-phospho-alpha-D-ribose-1-diphosphate synthetase (ribosephosphate pyrophosphokinase, EC 2.7.6.1) activity in rat hepatomas.
Carcinoma, Hepatocellular
Increased carbamoyl-phosphate synthetase II concentration in rat hepatomas: immunological evidence.
Carcinoma, Hepatocellular
Nucleotide interconversions. IV. Activities of deoxycytidylate deaminase and thymidylate synthetase in normal rat liver and hepatomas.
Carcinoma, Hepatocellular
Proliferation-linked increase in phosphoribosylformylglycinamidine synthetase activity (EC 6.3.5.3).
Carcinoma, Hepatocellular
Proportional activities of glycerol kinase and glycerol 3-phosphate dehydrogenase in rat hepatomas.
Carcinoma, Hepatocellular
Regulation and expression of carbamyl phosphate synthetase I mRNA in developing rat liver and Morris hepatoma 5123D.
Carcinoma, Hepatocellular
Regulatory properties and behavior of activity of carbamoyl phosphate synthetase II (glutamine-hydrolyzing) in normal and proliferating tissues.
Carcinoma, Hepatocellular
Studies on the biological functions of CPS1 in AFB1 induced hepatocarcinogenesis.
Carcinoma, Hepatocellular
Substrate and hormone regulation of palmitoyl-CoA synthetase in 7800 C1 Morris hepatoma cells and cultured rat hepatocytes.
Carcinoma, Hepatocellular
Synergistic Activation of the Nrf2-Signaling Pathway by Glyceollins under Oxidative Stress Induced by Glutathione Depletion.
Carcinoma, Hepatocellular
[Immunophenotypic classification of 3 cases of hepatocellular adenoma. Differential diagnosis with focal nodular hyperplasia].
Carcinoma, Hepatocellular
[Mechanism of carcinogenesis. VII. Biosynthesis of carbamyl phosphate synthetase I in vivo and in vitro in hepatocellular carcinoma and liver of rats fed with diethylnitrosamine]
Carcinoma, Hepatocellular
[Multivariate analysis of aminoacyl-tRNA synthetase activities of liver and hepatomas (author's transl)]
Carcinoma, Hepatocellular
[The coenzyme A and the activity of coenzyme A synthetase in hepatoma in the white rat]
Carcinoma, Lewis Lung
Proliferation-linked increase in phosphoribosylformylglycinamidine synthetase activity (EC 6.3.5.3).
Carcinoma, Non-Small-Cell Lung
IARS2 silencing induces non-small cell lung cancer cells proliferation inhibition, cell cycle arrest and promotes cell apoptosis.
Carcinoma, Non-Small-Cell Lung
Investigation of myositis and scleroderma specific autoantibodies in patients with lung cancer.
Carcinoma, Renal Cell
Hormonal and immunological regulation of 2', 5'-oligoadenylate synthetase activity in human peripheral blood mononuclear cells.
Carcinoma, Renal Cell
In vivo and in vitro induction of (2'-5') oligoadenylate synthetase by human interferons in leukocytes from healthy donors and patients with renal cancer and hairy cell leukemia.
Carcinoma, Renal Cell
Monitoring of interferon treatment in patients with renal cell carcinoma and bladder carcinoma by oligo-A synthetase assay and determination of immunological parameters.
Carcinoma, Renal Cell
Study of 2'5' oligo (A) synthetase in patients with metastatic renal cell carcinoma.
Carcinoma, Squamous Cell
Cancer-Specific Production of N-Acetylaspartate via NAT8L Overexpression in Non-Small Cell Lung Cancer and Its Potential as a Circulating Biomarker.
Carcinoma, Squamous Cell
Comparison of pyrimidine nucleotide synthetic enzymes involved in 5-fluorouracil metabolism between human adenocarcinomas and squamous cell carcinomas.
Cardiomyopathies
Exercise Training Reverses Lipotoxicity-induced Cardiomyopathy by Inhibiting HMGCS2.
Cardiomyopathies
Structural modeling of tissue-specific mitochondrial alanyl-tRNA synthetase (AARS2) defects predicts differential effects on aminoacylation.
Cardiotoxicity
A synopsis of research in cardiac apoptosis and its application to congestive heart failure.
Cardiovascular Diseases
The regulatory roles of aminoacyl-tRNA synthetase in cardiovascular disease.
Carotid Artery Thrombosis
The role of thromboxane (TX) A2 in rabbit arterial thrombosis induced by endothelial damage.
Cataract
Recessive Mutation in a Nuclear-Encoded Mitochondrial tRNA Synthetase Associated With Infantile Cataract, Congenital Neurotrophic Keratitis, and Orbital Myopathy.
Cerebral Hemorrhage
A comparison of interferon levels with leukocyte (2'-5') oligoadenylate synthetase activity as markers of viral encephalopathies.
Cerebral Hemorrhage
Activating PPAR? Increases NQO1 and ?-GCS Expression via Nrf2 in Thrombin-activated Microglia.
Cerebral Hemorrhage
Beneficial effects of acute intravenous ibuprofen on neurologic recovery of head-injured mice: comparison of cyclooxygenase inhibition with inhibition of thromboxane A2 synthetase or 5-lipoxygenase.
Cerebral Hemorrhage
Long non-coding RNA H19 protects against intracerebral hemorrhage injuries via regulating microRNA-106b-5p/acyl-CoA synthetase long chain family member 4 axis.
Cerebral Infarction
Pharmacological studies on the TXA2 synthetase inhibitor (E)-3-[p-(1H-imidazol-1-ylmethyl)phenyl]-2-propenoic acid (OKY-046).
Cerebral Infarction
Thromboxane synthetase inhibition in acute focal cerebral ischemia in cats.
Cerebral Palsy
Electrophysiological assessment of the effect of intrathecal baclofen in dystonic children.
Cerebral Palsy
Magnetic resonance imaging pattern recognition in childhood bilateral basal ganglia disorders.
Chagas Disease
Assessing gene expression during pathogenesis: Use of qRT-PCR to follow toxin production in the entomopathogenic fungus Beauveria bassiana during infection and immune response of the insect host Triatoma infestans.
Charcot-Marie-Tooth Disease
A novel AARS mutation in a family with dominant myeloneuropathy.
Charcot-Marie-Tooth Disease
Crystallization and preliminary X-ray analysis of a native human tRNA synthetase whose allelic variants are associated with Charcot-Marie-Tooth disease.
Charcot-Marie-Tooth Disease
Deficient activity of alanyl-tRNA synthetase underlies an autosomal recessive syndrome of progressive microcephaly, hypomyelination, and epileptic encephalopathy.
Chikungunya Fever
Association of Oligoadenylate Synthetase Gene Cluster and DC-SIGN (CD209) Gene Polymorphisms with Clinical Symptoms in Chikungunya Virus Infection.
Cholestasis
Effect of cholestasis and bile acids on interferon-induced 2',5'-adenylate synthetase and NK cell activities.
Cholestasis
Sphingosine 1-phosphate receptor-1 specific agonist SEW2871 ameliorates ANIT-induced dysregulation of bile acid homeostasis in mice plasma and liver.
Choline Deficiency
Regulation by dietary choline of hepatic fatty acid synthetase in the rat.
Choriocarcinoma
Characterization of a sodium-dependent vitamin transporter mediating the uptake of pantothenate, biotin and lipoate in human placental choriocarcinoma cells.
Choriocarcinoma
Human placental Na+-dependent multivitamin transporter. Cloning, functional expression, gene structure, and chromosomal localization.
Choroidal Neovascularization
Blockade of nitric-oxide synthase reduces choroidal neovascularization.
Chronic Periodontitis
Biochemical alterations in inflammatory periodontal diseases I. Poly (ADP-ribose) synthetase activity in gingiva and gingival fibroblasts from humans with periodontitis.
Citrullinemia
Allosteric and catalytic functions of the PPi-binding motif in the ATP sulfurylase-GTPase system.
Citrullinemia
Animal model of human disease. Citrullinemia (argininosuccinate synthetase deficiency).
Citrullinemia
First report of carglumic acid in a patient with citrullinemia type 1 (argininosuccinate synthetase deficiency).
Citrullinemia
Improving long term outcomes in urea cycle disorders-report from the Urea Cycle Disorders Consortium.
Citrullinemia
Neonatal citrullinemia associated with cutaneous manifestations and arginine deficiency.
Citrullinemia
Retroviral-mediated gene therapy for the treatment of citrullinemia. Transfer and expression of argininosuccinate synthetase in human hematopoietic cells.
Citrullinemia
Skin, hair and nail changes in a case of citrullinemia with late manifestation.
Citrullinemia
The first successful live birth following preimplantation genetic diagnosis using PCR for type 1 citrullinemia.
Citrullinemia
Urea Cycle Disorders: A Neuroimaging Pattern Approach Using Diffusion and FLAIR MRI.
Citrullinemia
[A case of citrullinemia associated with isolated ACTH deficiency, rapidly developing coma]
Coinfection
Three Gene Signature for Predicting the Development of Hepatocellular Carcinoma in Chronically Infected Hepatitis C Virus Patients.
Colic
Treatment of renal colic by prostaglandin synthetase inhibitors and avafortan (analgesic antispasmodic).
Colitis
Blockade of Poly(ADP-ribose) synthetase inhibits neutrophil recruitment, oxidant generation, and mucosal injury in murine colitis.
Colitis
Faecal diversion for Crohn's colitis: a model to study the role of the faecal stream in the inflammatory process.
Colitis
Host nuclear factor erythroid 2-related factor-2 defense system determines the outcome of dextran sulfate sodium-induced colitis in mice.
Colitis, Ulcerative
(2'-5') oligo adenylate synthetase activity in leucocytes of patients with inflammatory bowel disease.
Colitis, Ulcerative
(2'-5')Oligoadenylate synthetase activity in intestinal mononuclear and epithelial cells of inflammatory bowel disease patients.
Colitis, Ulcerative
Glucosamine synthetase activity of the colonic mucosa in ulcerative colitis and Crohn's disease.
Colitis, Ulcerative
Nonclinical Toxicology and Toxicokinetic Profile of an Oral Lanthionine Synthetase C-Like 2 (LANCL2) Agonist, BT-11.
Colitis, Ulcerative
Proceedings: Glucosamine synthetase activity in the colonic mucosa in ulcerative colitis and Crohn's disease.
Colitis, Ulcerative
The Safety, Tolerability, and Pharmacokinetics Profile of BT-11, an Oral, Gut-Restricted Lanthionine Synthetase C-Like 2 Agonist Investigational New Drug for Inflammatory Bowel Disease: A Randomized, Double-Blind, Placebo-Controlled Phase I Clinical Trial.
Collagen Diseases
[Serum 2-5 oligoadenylate synthetase activity in infectious diseases and collagen diseases in childhood]
Colonic Neoplasms
Do NSAIDs exert their colon cancer chemoprevention activities through the inhibition of mucosal prostaglandin synthetase?
Colonic Neoplasms
Elevated vitamin levels in colon adenocarcinoma as compared with metastatic liver adenocarcinoma from colon primary and normal adjacent tissue.
Colonic Neoplasms
Pharmacokinetic and biochemical studies on acivicin in phase I clinical trials.
Colonic Neoplasms
The cinnamon-derived dietary factor cinnamic aldehyde activates the Nrf2-dependent antioxidant response in human epithelial colon cells.
Colorectal Neoplasms
Expression of AIMP1, 2 and 3, the scaffolds for the multi-tRNA synthetase complex, is downregulated in gastric and colorectal cancer.
Colorectal Neoplasms
Frameshift Mutation of MARS Gene Encoding an Aminoacyl-tRNA Synthetase in Gastric and Colorectal Carcinomas with Microsatellite Instability.
Colorectal Neoplasms
Novel mRNA isoforms and mutations of uridine monophosphate synthetase and 5-fluorouracil resistance in colorectal cancer.
Colorectal Neoplasms
Prevalence and association of pks+ Escherichia coli with colorectal cancer in patients at the University Malaya Medical Centre, Malaysia.
Coma
ComA-dependent transcriptional activation of lichenysin A synthetase promoter in Bacillus subtilis cells.
Coma
Effect of inulin on efficient production and regulatory biosynthesis of bacillomycin D in Bacillus subtilis fmbJ.
Coma
Lichenysin production is improved in codY null Bacillus licheniformis by addition of precursor amino acids.
Communicable Diseases
[Serum 2-5 oligoadenylate synthetase activity in infectious diseases and collagen diseases in childhood]
Confusion
Structural organization of high-Mr mammalian aminoacyl-tRNA synthetases. Comparison of multi-enzyme complexes from different sources.
Congenital Microtia
Mass Spectrometric Characterization of Metabolites in Ear Cartilage: Congenital Microtia and Normal Auricle.
Connective Tissue Diseases
2',5'-oligoadenylate synthetase induction in lymphocytes of patients with connective tissue diseases.
Connective Tissue Diseases
Anti-transfer RNA antibodies in two patients with pulmonary fibrosis, Raynaud's phenomenon and polyarthritis.
Connective Tissue Diseases
Antisynthetase syndrome: An under-recognized cause of interstitial lung disease.
Connective Tissue Diseases
Clinicoserological features of antisynthetase syndrome (ASyS)-associated interstitial lung disease presenting to respiratory services: comparison with idiopathic pulmonary fibrosis and ASyS diagnosed in rheumatology services.
Connective Tissue Diseases
Pathogenic aspects of dermatomyositis, polymyositis and overlap myositis.
Coproporphyria, Hereditary
Hepatic delta-aminolaevulinic acid synthetase in an attack of hereditary coproporphyria and during remission.
Corneal Injuries
Half mustard (CEES) induced damage to rabbit cornea: attenuating effect of taurine-pyruvate-alpha-ketoglutarate-pantothenate mixture.
Corneal Neovascularization
Potential involvement of nitric oxide synthase but not inducible nitric oxide synthase in the development of experimental corneal neovascularization.
Coronary Occlusion
Inhibition of thromboxane A2 synthetase failed to limit myocardial infarct size in a rabbit ischemia-reperfusion model.
Coronary Occlusion
Myocardial salvage by a novel thromboxane A2 synthetase inhibitor in a canine coronary occlusion-reperfusion model.
Coronary Thrombosis
DTTX30, a combined thromboxane receptor antagonist and thromboxane synthetase inhibitor, prevents coronary thrombosis in anesthetized dogs.
Coronary Thrombosis
Effects of Y-20811, a thromboxane A2 synthetase inhibitor, on experimentally induced coronary thrombosis in anesthetized dogs.
Corticobasal Degeneration
Neuropathology and pathogenesis of extrapyramidal movement disorders: a critical update-I. Hypokinetic-rigid movement disorders.
Cough
Identification of viral infections in pregnancy by assay of (2'-5')-oligo-isoadenylate synthetase.
Cough
Thromboxane A2 synthetase inhibition suppresses cough induced by angiotensin converting enzyme inhibitors.
Craniocerebral Trauma
[Experimental substantiation of the method of pharmaco-metabolic brain protection against hypoxia in severe craniocerebral injury]
Crohn Disease
(2'-5') oligo adenylate synthetase activity in leucocytes of patients with inflammatory bowel disease.
Crohn Disease
(2'-5')Oligoadenylate synthetase activity in intestinal mononuclear and epithelial cells of inflammatory bowel disease patients.
Crohn Disease
Exploratory Studies With BT-11: A Proposed Orally Active Therapeutic for Crohn's Disease.
Crohn Disease
Glucosamine synthetase activity of the colonic mucosa in ulcerative colitis and Crohn's disease.
Crohn Disease
Nonclinical Toxicology and Toxicokinetic Profile of an Oral Lanthionine Synthetase C-Like 2 (LANCL2) Agonist, BT-11.
Crohn Disease
Proceedings: Glucosamine synthetase activity in the colonic mucosa in ulcerative colitis and Crohn's disease.
Crohn Disease
The Safety, Tolerability, and Pharmacokinetics Profile of BT-11, an Oral, Gut-Restricted Lanthionine Synthetase C-Like 2 Agonist Investigational New Drug for Inflammatory Bowel Disease: A Randomized, Double-Blind, Placebo-Controlled Phase I Clinical Trial.
Cryptosporidiosis
Spontaneous Selection of Cryptosporidium Drug Resistance in a Calf Model of Infection.
Cystic Fibrosis
Orthotopic liver transplantation in a patient with carbamyl phosphate synthetase deficiency and cystic fibrosis.
Cysts
Echinocandin treatment of pneumocystis pneumonia in rodent models depletes cysts leaving trophic burdens that cannot transmit the infection.
Cysts
Hyphal tip growth in Phytophthora. Gradient distribution and ultrahistochemistry of enzymes.
Deafness
Expanding the phenotype of PRPS1 syndromes in females: neuropathy, hearing loss and retinopathy.
Deafness
Inherited superactivity of phosphoribosylpyrophosphate synthetase: association of uric acid overproduction and sensorineural deafness.
Deafness
Magnetic resonance imaging pattern recognition in childhood bilateral basal ganglia disorders.
Dehydration
A novel Maize homeodomain-leucine zipper (HD-Zip) I gene, Zmhdz10, positively regulates drought and salt tolerance in both rice and Arabidopsis.
Dehydration
Cloning and characterization of a salt stress-inducible small GTPase gene from the model grass species Lolium temulentum.
Dehydration
Effect of ploidy levels on the activities of Delta(1)-pyrroline-5-carboxylate synthetase, superoxide dismutase and peroxidase in Cenchrus species grown under water stress.
Dehydration
Formation of an aminovinyl-cysteine residue in thioviridamides occurs through a path independent of known lanthionine synthetase activity.
Dehydration
Heterologous Biosynthesis, Modifications and Structural Characterization of Ruminococcin-A, a Lanthipeptide From the Gut Bacterium Ruminococcus gnavus E1, in Escherichia coli.
Dehydration
Identification of proteins regulated by cross-talk between drought and hormone pathways in Arabidopsis wild-type and auxin-insensitive mutants, axr1 and axr2.
Dehydration
Mechanistic investigations of the dehydration reaction of lacticin 481 synthetase using site-directed mutagenesis.
Dehydration
Mechanistic studies of Ser/Thr dehydration catalyzed by a member of the LanL lanthionine synthetase family.
Dehydration
Mutants of the zinc ligands of lacticin 481 synthetase retain dehydration activity but have impaired cyclization activity.
Dehydration
The importance of the leader sequence for directing lanthionine formation in lacticin 481.
Dementia
Neuropathology and pathogenesis of extrapyramidal movement disorders: a critical update-I. Hypokinetic-rigid movement disorders.
Dementia
Sleep in genetically confirmed pantothenate kinase-associated neurodegeneration: a video-polysomnographic study.
Dengue
Glycogen synthetase kinase 3 inhibition drives MIC-A/B to promote cytokine production by human natural killer cells in Dengue virus type 2 infection.
Dengue
Polymorphisms in the oligoadenylate synthetase gene cluster and its association with clinical outcomes of dengue virus infection.
Dental Caries
NagR Differentially Regulates the Expression of the glmS and nagAB Genes Required for Amino Sugar Metabolism by Streptococcus mutans.
Dermatitis
Calcium pantothenate is present in cosmetics and may cause allergic contact dermatitis.
Dermatitis, Allergic Contact
Calcium pantothenate is present in cosmetics and may cause allergic contact dermatitis.
Dermatomyositis
A retrospective cohort study in Chinese patients with adult polymyositis and dermatomyositis: risk of comorbidities and subclassification using machine learning.
Dermatomyositis
Analysis of dermatomyositis-specific autoantibodies and clinical characteristics in Japanese patients.
Dermatomyositis
Anti-aminoacyl tRNA Synthetase Antibody-Positive Clinically Amyopathic Dermatomyositis.
Dermatomyositis
Anti-Ro52 autoantibodies are associated with interstitial lung disease and more severe disease in patients with juvenile myositis.
Dermatomyositis
Clinical and immunogenetic features of patients with autoantibodies to asparaginyl-transfer RNA synthetase.
Dermatomyositis
Clinical evaluation of anti-aminoacyl tRNA synthetase antibodies in Japanese patients with dermatomyositis.
Dermatomyositis
Clinical manifestations of skin, lung and muscle diseases in dermatomyositis positive for anti-aminoacyl tRNA synthetase antibodies.
Dermatomyositis
Clinical significance and new detection system of autoantibodies in myositis with interstitial lung disease.
Dermatomyositis
Comparison of long-term prognosis and relapse of dermatomyositis complicated with interstitial pneumonia according to autoantibodies: anti-aminoacyl tRNA synthetase antibodies versus anti-melanoma differentiation-associated gene 5 antibody.
Dermatomyositis
Correlation of Antisynthetase Antibody Levels with Disease Course in a Patient with Interstitial Lung Disease and Elevated Muscle Enzymes.
Dermatomyositis
Distinct clinical and histological features in dermatomyositis with anti-aminoacyl-tRNA synthetase antibodies.
Dermatomyositis
Genome-wide association study identifies HLA 8.1 ancestral haplotype alleles as major genetic risk factors for myositis phenotypes.
Dermatomyositis
Inflammatory myopathy, bronchiolitis obliterans/organizing pneumonia, and anti-Jo-1 antibodies--an interesting association.
Dermatomyositis
Macromolecular creatine kinase Type 1 in a patient with anti-aminoacyl-tRNA synthetase autoantibody-related dermatomyositis.
Dermatomyositis
Plasma homocysteine levels are positively associated with interstitial lung disease in dermatomyositis patients with anti-aminoacyl-tRNA synthetase antibody.
Dermatomyositis
Potential of Krebs von den Lungen-6 as a predictor of relapse in interstitial pneumonia with anti-aminoacyl tRNA synthetase antibodies-positive dermatomyositis.
Dermatomyositis
Reliability and clinical utility of Enzyme-linked immunosorbent assay for detection of anti-aminoacyl-tRNA synthetase antibody.
Dermatomyositis
The comparison of nailfold videocapillaroscopy findings between anti-melanoma differentiation-associated gene 5 antibody and anti-aminoacyl tRNA synthetase antibody in patients with dermatomyositis complicated by interstitial lung disease.
Dermatomyositis
Treatment of idiopathic inflammatory myositis associated interstitial lung disease: A systematic review and meta-analysis.
Dermatomyositis
Two cases with autoantibodies to small ubiquitin-like modifier activating enzyme: A potential unique subset of dermatomyositis-associated interstitial lung disease.
Diabetes Insipidus, Nephrogenic
Hydrochlorothiazide-amiloride in the treatment of congenital nephrogenic diabetes insipidus.
Diabetes Mellitus
Amelioration of diabetes mellitus in partially depancreatized rats by poly(ADP-ribose) synthetase inhibitors. Evidence of islet B-cell regeneration.
Diabetes Mellitus
Autoantibodies against aminoacyl-tRNA synthetase: novel diagnostic marker for type 1 diabetes mellitus.
Diabetes Mellitus
Decreased expression of TNFRSF12A in thyroid gland cancer predicts poor prognosis: A study based on TCGA data.
Diabetes Mellitus
Induction of islet B-cell regeneration in partially pancreatectomized rats by poly(ADP-ribose) synthetase inhibitors.
Diabetes Mellitus
Low intakes of carotene, vitamin?B2 , pantothenate and calcium predict cognitive decline among elderly patients with diabetes mellitus: The Japanese Elderly Diabetes Intervention Trial.
Diabetes Mellitus
Muscle glycogen and glycogen synthetase in normal subjects and in patients with diabetes mellitus. Effect of intravenous glucose and insulin administration.
Diabetes Mellitus
Muscle glycogen synthetase in patients with diabetes mellitus. Basal values, effect of glycogen depletion by exercise, and effect of treatment.
Diabetes Mellitus
Role of poly(ADP-ribose) synthetase in inflammation and ischaemia-reperfusion.
Diabetes Mellitus
The Reg gene family and Reg proteins: with special attention to the regeneration of pancreatic beta-cells.
Diabetes Mellitus
Vascular endothelium dysfunction: a conservative target in metabolic disorders.
Diabetes Mellitus, Experimental
Tissue concentrations of water-soluble vitamins in normal and diabetic rats.
Diabetes Mellitus, Experimental
[The effect of a water-soluble vitamins on the activity of some enzymes in diabetes.]
Diabetes Mellitus, Type 1
Autoantibodies against aminoacyl-tRNA synthetase: novel diagnostic marker for type 1 diabetes mellitus.
Diabetes Mellitus, Type 1
No evidence for association of OAS1 with type 1 diabetes in unaffected siblings or type 1 diabetic cases.
Diabetes Mellitus, Type 2
AMPK in the small intestine in normal and pathophysiological conditions.
Diabetes Mellitus, Type 2
Effect of acute thromboxane A2 inhibition on the renal hemodynamics in a spontaneously non-insulin-dependent diabetic rat, Otsuka Long-Evans Tokushima Fatty rat.
Diabetes Mellitus, Type 2
Evidence that the mitochondrial leucyl tRNA synthetase (LARS2) gene represents a novel type 2 diabetes susceptibility gene.
Diabetes Mellitus, Type 2
Molecular modeling of lanthionine synthetase component C-like protein 2: a potential target for the discovery of novel type 2 diabetes prophylactics and therapeutics.
Diabetes Mellitus, Type 2
Pathogenesis of obesity by food restriction in OLETF rats-increased intestinal monoacylglycerol acyltransferase activities may be a crucial factor.
Diabetes Mellitus, Type 2
Picotamide, a dual TXB synthetase inhibitor and TXB receptor antagonist, reduces exercise-induced albuminuria in microalbuminuric patients with NIDDM.
Diabetic Nephropathies
Evaluation of associations between single nucleotide polymorphisms in the FRMD3 and CARS genes and diabetic nephropathy in a Kuwaiti population.
Diabetic Nephropathies
UPLC-MS-based urine nontargeted metabolic profiling identifies dysregulation of pantothenate and CoA biosynthesis pathway in diabetic kidney disease.
Diphtheria
Studies on Corynebacterium diphtheriae. V. The attitude of diphtheria bacillus to some growth factors (calcium pantothenate, glutamic acid and tryptophane).
Down Syndrome
Increased activity of oligo-2',5'-adenylate synthetase in Down's syndrome and epilepsy.
Down Syndrome
Interferon induction of (2'-5') oligoisoadenylate synthetase in diploid and trisomy 21 human fibroblasts: relation to dosage of the interferon receptor gene (IRFC).
Down Syndrome
Neuronal plasticity and astrocytic reaction in Down syndrome and Alzheimer disease.
Down Syndrome
Pantothenate kinase-associated neurodegeneration (PKAN) in a child with Down syndrome. A case report and follow-up with MRI.
Drug Resistant Epilepsy
Novel Compound Heterozygous Mutations Expand the Recognized Phenotypes of FARS2-Linked Disease.
Ductus Arteriosus, Patent
Efficacy of paracetamol for the treatment of patent ductus arteriosus in preterm neonates.
Duodenal Ulcer
Attenuation of cysteamine-induced duodenal ulcer with Cochinchina momordica seed extract through inhibiting cytoplasmic phospholipase A2/5-lipoxygenase and activating ?-glutamylcysteine synthetase.
Dysarthria
Metabolic consequences of mitochondrial coenzyme A deficiency in patients with PANK2 mutations.
Dysarthria
Pantethine treatment is effective in recovering the disease phenotype induced by ketogenic diet in a pantothenate kinase-associated neurodegeneration mouse model.
Dysarthria
Partial deficit of pantothenate kinase 2 catalytic activity in a case of tremor-predominant neurodegeneration with brain iron accumulation.
Dysarthria
Subthalamic Nuclei Stimulation in Patients With Pantothenate Kinase-Associated Neurodegeneration (PKAN).
Dyskinesias
Subthalamic Nuclei Stimulation in Patients With Pantothenate Kinase-Associated Neurodegeneration (PKAN).
Dyskinesias
[CHOLINE PANTOTHENATE IN THE THERAPY OF ATONIAS AND DYSKINESIAS OF THE BILIARY TRACT.]
Dystonia
4'-Phosphopantetheine corrects CoA, iron, and dopamine metabolic defects in mammalian models of PKAN.
Dystonia
A patient with pantothenate kinase-associated neurodegeneration and supranuclear gaze palsy.
Dystonia
Botulinum Toxin-A Injection in the Treatment of Spasticity in a Infantile-Onset Neurodegeneration With Brain Iron Accumulation: A Case Report.
Dystonia
Cerebral blood flow in dystonia due to pantothenate kinase-associated neurodegeneration.
Dystonia
Changes of cerebral white matter in patients suffering from Pantothenate Kinase-Associated Neurodegeneration (PKAN): A diffusion tensor imaging (DTI) study.
Dystonia
Characteristic "Forcible" Geste Antagoniste in Oromandibular Dystonia Resulting From Pantothenate Kinase-Associated Neurodegeneration.
Dystonia
Deep brain stimulation as treatment for dystonic storm in pantothenate kinase-associated neurodegeneration syndrome: case report of a patient with homozygous C.628 2 T?>?G mutation of the PANK2 gene.
Dystonia
Deep brain stimulation for pantothenate kinase-associated neurodegeneration: A meta-analysis.
Dystonia
Deep brain stimulation improves quality of life in pantothenate kinase-associated neurodegeneration.
Dystonia
Dental appliance therapy in pantothenate kinase-associated neurodegeneration: Case report.
Dystonia
Electrophysiological assessment of the effect of intrathecal baclofen in dystonic children.
Dystonia
Grey matter alterations in patients with Pantothenate Kinase-Associated Neurodegeneration (PKAN).
Dystonia
Identification of a highly polymorphic microsatellite VNTR within the argininosuccinate synthetase locus: exclusion of the dystonia gene on 9q32-34 as the cause of dopa-responsive dystonia in a large kindred.
Dystonia
Long-term benefit to pallidal deep brain stimulation in a case of dystonia secondary to pantothenate kinase-associated neurodegeneration.
Dystonia
Low-frequency rTMS of the premotor cortex reduces complex movement patterns in a patient with pantothenate kinase-associated neurodegenerative disease (PKAN).
Dystonia
Metabolic consequences of mitochondrial coenzyme A deficiency in patients with PANK2 mutations.
Dystonia
Neuronal Ablation of CoA Synthase Causes Motor Deficits, Iron Dyshomeostasis, and Mitochondrial Dysfunctions in a CoPAN Mouse Model.
Dystonia
Pallidal stimulation for dystonia in pantothenate kinase-associated neurodegeneration.
Dystonia
Pallidal stimulation for pantothenate kinase-associated neurodegeneration dystonia.
Dystonia
Pantethine treatment is effective in recovering the disease phenotype induced by ketogenic diet in a pantothenate kinase-associated neurodegeneration mouse model.
Dystonia
Partial deficit of pantothenate kinase 2 catalytic activity in a case of tremor-predominant neurodegeneration with brain iron accumulation.
Dystonia
Safety and efficacy of deferiprone for pantothenate kinase-associated neurodegeneration: a randomised, double-blind, controlled trial and an open-label extension study.
Dystonia
Sensory Tricks in Pantothenate Kinase-Associated Neurodegeneration: Video-Analysis of 43 Patients.
Dystonia
Subthalamic Nuclei Stimulation in Patients With Pantothenate Kinase-Associated Neurodegeneration (PKAN).
Dystonia
The eye-of-the-tiger sign is not a reliable disease marker for Hallervorden-Spatz syndrome.
Dystonic Disorders
A pilot trial of deferiprone for neurodegeneration with brain iron accumulation.
Dystonic Disorders
Clinical and neuropsychological correlates in two brothers with pantothenate kinase-associated neurodegeneration.
Echinococcosis
Metabolic profiling of liver and faeces in mice infected with echinococcosis.
Embolism, Air
Effect of thromboxane synthetase inhibitors (OKY-046, OKY-1580) on experimentally induced air embolism in anesthetized dogs.
Encephalitis, Viral
A comparison of interferon levels with leukocyte (2'-5') oligoadenylate synthetase activity as markers of viral encephalopathies.
Encephalomyelitis, Autoimmune, Experimental
Role of poly(ADP-ribose) synthetase activation in the development of experimental allergic encephalomyelitis.
Endometrial Neoplasms
Cholesterol Synthetase DHCR24 Induced by Insulin Aggravates Cancer Invasion and Progesterone Resistance in Endometrial Carcinoma.
Endometrial Neoplasms
Hormone dependency of carcinoma of the human endometrium. Effect of progesterone on glycogen metabolism in the carcinoma tissue.
Endotoxemia
Effects of nicotinamide, an inhibitor of PARS activity, on gut and liver O2 exchange and energy metabolism during hyperdynamic porcine endotoxemia.
Endotoxemia
Platelet-endothelial cell interaction in pulmonary micro-circulation: the role of PARS.
Endotoxemia
Poly(Adp-ribose) synthetase inhibition prevents lipopolysaccharide-induced peroxynitrite mediated damage in diaphragm.
Endotoxemia
The role of poly(ADP-ribose) synthetase inhibition in preventing endotoxemia-induced intestinal epithelial apoptosis.
Eosinophilia
Fusion of TEL/ETV6 to a novel ACS2 in myelodysplastic syndrome and acute myelogenous leukemia with t(5;12)(q31;p13).
Epilepsy
FARS2 mutation and epilepsy: Possible link with early-onset epileptic encephalopathy.
Epilepsy
Increased activity of oligo-2',5'-adenylate synthetase in Down's syndrome and epilepsy.
Epilepsy
Lethal NARS2-Related Disorder Associated With Rapidly Progressive Intractable Epilepsy and Global Brain Atrophy.
Epilepsy
Lipoic acid synthetase deficiency causes neonatal-onset epilepsy, defective mitochondrial energy metabolism, and glycine elevation.
Epilepsy
Mutations in QARS, Encoding Glutaminyl-tRNA Synthetase, Cause Progressive Microcephaly, Cerebral-Cerebellar Atrophy, and Intractable Seizures.
Epilepsy
The anticonvulsant actions of carisbamate associate with alterations in astrocyte glutamine metabolism in the lithium-pilocarpine epilepsy model.
Epstein-Barr Virus Infections
Increased (2'-5')-oligo-A synthetase activity in patients with prolonged illness associated with serological evidence of persistent Epstein-Barr virus infection.
Esophageal Squamous Cell Carcinoma
Using Q-RT-PCR to measure cyclin D1, TS, TP, DPD, and Her-2/neu as predictors for response, survival, and recurrence in patients with esophageal squamous cell carcinoma following radiochemotherapy.
Essential Hypertension
Two medium-chain acyl-coenzyme A synthetase genes, SAH and MACS1, are associated with plasma high-density lipoprotein cholesterol levels, but they are not associated with essential hypertension.
Essential Tremor
Pantothenate kinase-associated neurodegeneration initially presenting as postural tremor alone in a Japanese family with homozygous N245S substitutions in the pantothenate kinase gene.
Exophthalmos
Effect of prostaglandin synthetase inhibitors on non-analgesic actions of morphine.
Fasciitis
Angiogenesis and VEGF-expressing cells are identified predominantly in the fascia rather than in the muscle during the early phase of dermatomyositis.
Fatigue Syndrome, Chronic
Changes in the 2-5A synthetase/RNase L antiviral pathway in a controlled clinical trial with poly(I)-poly(C12U) in chronic fatigue syndrome.
Fatigue Syndrome, Chronic
Diagnostic evaluation of 2', 5'-oligoadenylate synthetase activities and antibodies against Epstein-Barr virus and Coxiella burnetii in patients with chronic fatigue syndrome in Japan.
Fatigue Syndrome, Chronic
Upregulation of the 2-5A synthetase/RNase L antiviral pathway associated with chronic fatigue syndrome.
Fatty Liver
Differential mechanisms regarding triclosan vs. bisphenol A and fluorene-9-bisphenol induced zebrafish lipid-metabolism disorders by RNA-Seq.
Fatty Liver
Effects of dietary fructose or glucose on triglyceride production and lipogenic enzyme activities in the liver of Wistar fatty rats, an animal model of NIDDM.
Fatty Liver
Fatty liver in hypervitaminosis A: synthesis and release of hepatic triglycerides.
Fatty Liver
Kipid metabolism in the rats with fatty liver caused by low protein diet and effects of the oral administration of L-methionine, L-cysteine, pantethine and calcium pantothenate upon it.
Fatty Liver, Alcoholic
Hepatic lipogenesis and mobilization of peripheral fats in the formation of alcoholic fatty liver.
Fibrosarcoma
Abnormal glutathione and sulfate levels after interleukin 6 treatment and in tumor-induced cachexia.
Flavivirus Infections
Analysis of the Relationship Between Enzymatic and Antiviral Activities of the Chicken Oligoadenylate Synthetase-Like.
Flavivirus Infections
The Flvr-encoded murine oligoadenylate synthetase 1b (Oas1b) suppresses 2-5A synthesis in intact cells.
Friedreich Ataxia
New Perspectives in Iron Chelation Therapy for the Treatment of Neurodegenerative Diseases.
Friedreich Ataxia
Synthesis of 5-[(1H-indol-3-yl)methyl]-1,3,4-oxadiazole-2(3H)-thiones and their protective activity against oxidative stress.
Friedreich Ataxia
The History of Deferiprone (L1) and the Paradigm of the Complete Treatment of Iron Overload in Thalassaemia.
Gastroenteritis
Efficacy and safety of i.v. sodium benzoate in urea cycle disorders: a multicentre retrospective study.
Gastroenteritis
Induction of the 2-5A system by interferon and transmissible gastroenteritis virus.
Genetic Diseases, Inborn
A patient with pantothenate kinase-associated neurodegeneration and supranuclear gaze palsy.
Genetic Diseases, Inborn
Basal ganglia calcification and novel compound heterozygous mutations in the PANK2 gene in a Chinese boy with classic Pantothenate kinase-associated neurodegeneration: A case report.
Genetic Diseases, Inborn
Biallelic IARS Mutations Cause Growth Retardation with Prenatal Onset, Intellectual Disability, Muscular Hypotonia, and Infantile Hepatopathy.
Genetic Diseases, Inborn
Divergent Cytochrome c Maturation System in Kinetoplastid Protists.
Genetic Diseases, Inborn
Glycyl tRNA synthetase mutations in Charcot-Marie-Tooth disease type 2D and distal spinal muscular atrophy type V.
Genetic Diseases, Inborn
Identification and targeted management of a neurodegenerative disorder caused by biallelic mutations in SLC5A6.
Genetic Diseases, Inborn
Magnetic resonance imaging pattern recognition in childhood bilateral basal ganglia disorders.
Genetic Diseases, Inborn
Safety and efficacy of deferiprone for pantothenate kinase-associated neurodegeneration: a randomised, double-blind, controlled trial and an open-label extension study.
Genetic Diseases, Inborn
Subthalamic Nuclei Stimulation in Patients With Pantothenate Kinase-Associated Neurodegeneration (PKAN).
Glaucoma, Open-Angle
Inducible and endothelial nitric synthetase expression and nitrotyrosine accumulation in iris vasculature of patients with primary open-angle glaucoma: a pilot study.
Glioblastoma
Cancer Association Study of Aminoacyl-tRNA Synthetase Signaling Network in Glioblastoma.
Glioblastoma
Identification of prognostic values defined by copy number variation, mRNA and protein expression of LANCL2 and EGFR in glioblastoma patients.
Glioblastoma
Nuclear factor kappa B dependent induction of gamma glutamylcysteine synthetase by ionizing radiation in T98G human glioblastoma cells.
Glioma
Antitumour effect of interferon combined with hyperthermia against experimental brain tumour.
Glioma
Buthionine sulfoximine induction of gamma-L-glutamyl-L-cysteine synthetase gene expression, kinetics of glutathione depletion and resynthesis, and modulation of carmustine-induced DNA-DNA cross-linking and cytotoxicity in human glioma cells.
Glioma
Therapeutic strategy for targeting aggressive malignant gliomas by disrupting their energy balance.
Glomerulonephritis
Clinical effects of selective thromboxane A2 synthetase inhibitor in patients with nephrotic syndrome.
Glomerulonephritis
Effects of a selective thromboxane A2 synthetase inhibitor on immune complex glomerulonephritis.
Glomerulonephritis
[Association of the complex of polymorphic markers of ACE genes, aldosteron synthetase and endothelial synthetase of nitric oxide with progression of chronic glomerulonephritis]
Glomerulonephritis
[The role of polymorphic markers of vasoactive hormones genes in clinical characteristics of chronic glomerulonephritis]
glucose-6-phosphatase deficiency
Disorders associated with purine and pyrimidine metabolism.
glutamate synthase (nadph) deficiency
Roles of SpoT and FNR in NH4+ assimilation and osmoregulation in GOGAT (glutamate synthase)-deficient mutants of Escherichia coli.
Glycogen Storage Disease
Activities of glycogen synthetase and UDPG-pyrophosphorylase in muscle of a patient with a new type of muscle glycogenosis caused by phosphofructokinase deficiency.
Glycogen Storage Disease
[Glycogenosis with probable glycogen synthetase deficiency in a 4-year-old boy]
Glycogen Storage Disease
[Three congenital metabolic diseases in the Faeroe Islands. Incidence, clinical and molecular genetic characteristics of Faeroese children with glycogen storage disease type IIIA, carnitine transporter deficiency and holocarboxylase synthetase deficiency]
Gout
A gouty family with increased phosphoribosylpyrophosphate synthetase activity: case reports, familial studies, and kinetic studies of the abnormal enzyme.
Gout
Accelerated transcription of PRPS1 in X-linked overactivity of normal human phosphoribosylpyrophosphate synthetase.
Gout
Altered isoelectric property of a superactive 5-phosphoribosyl-1-pyrophosphate (PRPP) synthetase in a patient with clinical gout.
Gout
Diagnostic evaluation of phosphoribosylpyrophosphate synthetase activities in hemolysates.
Gout
Effect of treatment on erythrocyte phosphoribosyl pyrophosphate synthetase and glutathione reductase activity in patients with primary gout.
Gout
Increased PP-ribose-P synthetase activity: a genetic abnormality leading to excessive purine production and gout.
Gout
Inherited superactivity of phosphoribosylpyrophosphate synthetase: association of uric acid overproduction and sensorineural deafness.
Gout
Overproduction disease in man due to enzyme feedback resistance mutation. Purine overproduction in gout due to excessive activity of mutant feedback-resistant phosphoribosylpyrophosphate synthetase.
Gout
Patterns of phosphoribosylpyrophosphate and ribose-5-phosphate concentration and generation in fibroblasts from patients with gout and purine overproduction.
Gout
Superactivity of phosphoribosylpyrophosphate synthetase, due to feedback resistance, causing purine overproduction and gout.
Gout
The mode of genetic transmission of gouty family with increased phosphoribosylpyrophosphate synthetase activity.
Gout
[Phosphoribosylpyrophosphate synthetase anomalies in 2 cases of gout beginning at an early age]
Granuloma
Pharmacologic properties of some derivatives of N-(2-carboxyphenyl)-4-phenoxyacetamide.
Graves Disease
Inhibitory effects of nicotinamide on intercellular adhesion molecule-1 expression on cultured human thyroid cells.
Graves Disease
Nicotinamide and 3-aminobenzamide inhibit recombinant human interferon-gamma-induced HLA-DR antigen expression, but not HLA-A, B, C antigen expression, on cultured human thyroid cells.
Graves Ophthalmopathy
Nicotinamide decreases cytokine-induced activation of orbital fibroblasts from patients with thyroid-associated ophthalmopathy.
Hearing Loss, Noise-Induced
Involvement of poly(ADP-ribose) synthetase in acoustic trauma of the cochlea.
Hearing Loss, Sensorineural
Novel, Compound Heterozygous, Single Nucleotide Variants in MARS2 Associated with Developmental Delay, Poor Growth, and Sensorineural Hearing Loss.
Heart Arrest
Poly-ADP-ribose polymerase inhibition protects against myocardial and endothelial reperfusion injury after hypothermic cardiac arrest.
Heart Defects, Congenital
MTHFD1 formyltetrahydrofolate synthetase deficiency, a model for the MTHFD1 R653Q variant, leads to congenital heart defects in mice.
Heart Failure
Fish oil selectively improves heart function in a mouse model of lipid-induced cardiomyopathy.
Hepatic Encephalopathy
Copper, Iron, and Manganese Toxicity in Neuropsychiatric Conditions.
Hepatitis
2',5' Oligoadenylate synthetase activity in peripheral blood mononuclear cells and serum during interferon treatment of chronic non-A, non-B hepatitis.
Hepatitis
Activities of 2'-5'oligoadenylate synthetase in peripheral blood mononuclear cells of patients with viral hepatitis, and chronic type B hepatitis during interferon therapy.
Hepatitis
Cell-type-specific activation of the oligoadenylate synthetase-RNase L pathway by a murine coronavirus.
Hepatitis
Detection of 2',5' oligoadenylate synthetase activity in acute viral hepatitis with special reference to histologic features in the acute stage.
Hepatitis
Indomethacin enhances serum 2'5'-oligoadenylate synthetase in patients with hepatitis B and C virus chronic active hepatitis.
Hepatitis
Serum 2'-5'oligoadenylate synthetase as a monitoring marker of anti-viral effect during interferon therapy for chronic type B hepatitis.
Hepatitis
[Non-specific immune response in acute viral hepatitis: studies from serum 2,5-oligoadenylate synthetase activity and serum and histochemical changes in beta 2 microglobulin]
Hepatitis
[Urinary excretion of microbiologically detectable forms of pantothenic acid in viral hepatitis]
Hepatitis A
Detection of 2',5' oligoadenylate synthetase activity in acute viral hepatitis with special reference to histologic features in the acute stage.
Hepatitis B
2',5'-Oligoadenylate synthetase activity in the liver and peripheral blood mononuclear cells of chronic hepatitis patients.
Hepatitis B
Carbohydrate-dependent biological activities of glycosylated human interferon-beta on human hepatoblastoma cells in vitro.
Hepatitis B
Evidence for a deficiency of interferon production in patients with chronic hepatitis B virus infection acquired in adult life.
Hepatitis B
Indomethacin enhances serum 2'5'-oligoadenylate synthetase in patients with hepatitis B and C virus chronic active hepatitis.
Hepatitis B
The sequential change of serum 2',5' oligoadenylate synthetase in different infectious patterns of duck hepatitis B virus in ducks in experimental transmission.
Hepatitis B
[Changes in serum levels of beta 2-microglobulin, neopterin and 2',5'-oligoadenylate synthase activity during clearance of hepatitis B virus with or without acute phase in transaminases]
Hepatitis B, Chronic
2',5'-Oligoadenylate synthetase activity in peripheral blood lymphocytes as a clinical marker in interferon therapy for chronic hepatitis B.
Hepatitis B, Chronic
Activities of the interferon system in patients with HBsAg-positive chronic hepatitis B during short-term steroid withdrawal therapy.
Hepatitis B, Chronic
Decreased interferon binding capacity of peripheral blood mononuclear cells during interferon treatment of chronic hepatitis B with special reference to (2'-5') oligoadenylate synthetase activity.
Hepatitis C
Indomethacin enhances serum 2'5'-oligoadenylate synthetase in patients with hepatitis B and C virus chronic active hepatitis.
Hepatitis C
Specific activation of 2'-5'oligoadenylate synthetase gene promoter by hepatitis C virus-core protein: a potential for developing hepatitis C virus targeting gene therapy.
Hepatitis C, Chronic
2'-,5'-Oligoadenylate synthetase response ratio predicting virological response to PEG-interferon-alpha2b plus ribavirin therapy in patients with chronic hepatitis C.
Hepatitis C, Chronic
Changes of serum 2',5'-oligoadenylate synthetase activity during interferon treatment of chronic hepatitis C.
Hepatitis C, Chronic
Factors influencing the response to interferon therapy in chronic hepatitis C. Studies on viral genotype and induction of 2',5'-oligoadenylate synthetase in the liver and peripheral blood cells.
Hepatitis E
Determination of hepatitis E virus seroprevalence by using recombinant fusion proteins and synthetic peptides.
Hepatitis, Chronic
Indomethacin enhances serum 2'5'-oligoadenylate synthetase in patients with hepatitis B and C virus chronic active hepatitis.
Hepatitis, Chronic
[Mechanisms of the effect of interferon (IFN) therapy in patients with type B and C chronic hepatitis]
Hepatoblastoma
Pharmacokinetics and biologic activities of human native and asialointerferon-beta s.
Hepatolenticular Degeneration
Neuropareidolia: diagnostic clues apropos of visual illusions.
Hepatolenticular Degeneration
Neuropathology and pathogenesis of extrapyramidal movement disorders: a critical update-I. Hypokinetic-rigid movement disorders.
Hepatolenticular Degeneration
Parkinson's Disease and Metal Storage Disorders: A Systematic Review.
Hepatomegaly
Liver-targeted disruption of Apc in mice activates beta-catenin signaling and leads to hepatocellular carcinomas.
Hepatomegaly
The hypolipidemic peroxisome-proliferating drug, bis(carboxymethylthio)-1.10 decane, a dicarboxylic metabolite of tiadenol, is activated to an acylcoenzyme A thioester.
Heredodegenerative Disorders, Nervous System
Atypical pantothenate kinase-associated neurodegeneration with variable phenotypes in an Egyptian family.
Herpes Zoster
Adrenocortical-specific transgene expression directed by steroid hydroxylase gene promoters.
Herpes Zoster
Exploring polymorphisms and effects of candidate genes on milk fat quality in dairy sheep.
Hirschsprung Disease
[Nitric oxide and Hirschsprung's disease: a causal relation biochemically, immunohistochemically and functionally demonstrated]
HIV Infections
2',5'-oligoadenylate synthetase, neopterin and beta 2-microglobulin in asymptomatic HIV-infected individuals.
HIV Infections
Modulation of nuclear matrix-associated 2',5'-oligoadenylate metabolism and ribonuclease L activity in H9 cells by human immunodeficiency virus.
Holocarboxylase Synthetase Deficiency
Deficiency of biotinyl-AMP synthetase activity in fibroblasts of patients with holocarboxylase synthetase deficiency.
Holocarboxylase Synthetase Deficiency
[Three congenital metabolic diseases in the Faeroe Islands. Incidence, clinical and molecular genetic characteristics of Faeroese children with glycogen storage disease type IIIA, carnitine transporter deficiency and holocarboxylase synthetase deficiency]
Huntington Disease
Changes in nine enzyme markers for neurons, glia, and endothelial cells in agonal state and Huntington's disease caudate nucleus.
Huntington Disease
Chasing shadows: What determines DTI metrics in gray matter regions? An in vitro and in vivo study.
Huntington Disease
New Perspectives in Iron Chelation Therapy for the Treatment of Neurodegenerative Diseases.
Huntington Disease
Vitamin B5 (d-pantothenic acid) localizes in myelinated structures of the rat brain: Potential role for cerebral vitamin B5 stores in local myelin homeostasis.
Hyperaldosteronism
[Subclinical endothelial inflammation markers in a family with type I familial hyperaldosteronism caused by a de novo mutation]
Hyperalgesia
Primary afferent nociceptor mechanisms mediating NGF-induced mechanical hyperalgesia.
Hyperalgesia
Roles of thromboxane A2 and leukotriene B4 in radicular pain induced by herniated nucleus pulposus.
Hyperargininemia
Efficacy and safety of i.v. sodium benzoate in urea cycle disorders: a multicentre retrospective study.
Hyperargininemia
Improving long term outcomes in urea cycle disorders-report from the Urea Cycle Disorders Consortium.
Hypercholesterolemia
Vascular endothelium dysfunction: a conservative target in metabolic disorders.
Hypercholesterolemia
[A case report of unusual retinal findings in a patient with Zieve syndrome]
Hyperglycemia
A woman with anti-histidyl-aminoacyl-tRNA synthetase (Jo-1 antibodies), myositis, hyperglycemia, interstitial lung disease, and morbilliform rashes.
Hyperglycemia
Effects of dietary fructose or glucose on triglyceride production and lipogenic enzyme activities in the liver of Wistar fatty rats, an animal model of NIDDM.
Hyperglycemia
Hyperglycemia and glycogen storage in the rabbit fetal liver. Role of age and hormonal status.
Hyperhomocysteinemia
Vascular endothelium dysfunction: a conservative target in metabolic disorders.
Hyperinsulinism
Effects of dietary fructose or glucose on triglyceride production and lipogenic enzyme activities in the liver of Wistar fatty rats, an animal model of NIDDM.
Hyperlipidemias
Effects of clofibric acid on the biliary excretion of benoxaprofen glucuronide and taurine conjugate in rats.
Hyperlipidemias
Enhanced expression of hepatic acyl-coenzyme A synthetase and microsomal triglyceride transfer protein messenger RNAs in the obese and hypertriglyceridemic rat with visceral fat accumulation.
Hypersensitivity
A double-blind, placebo-controlled trial of the thromboxane synthetase blocker OKY-046 on bronchial hypersensitivity in bronchial asthma patients.
Hypersensitivity
Effect of thromboxane A2 synthetase inhibitor on immediate-type hypersensitivity reactions.
Hypersensitivity
OsNAR2.1 interaction with OsNIT1 and OsNIT2 functions in root-growth responses to nitrate and ammonium.
Hypersensitivity
The role of thromboxane A2 (TxA2) in allergic cutaneous reactions and the effect of (E)-3-[p-(1H-imidazol-1-ylmethyl) phenyl]-2-propenoic acid hydrochloride (OKY-046), a TxA2 synthetase inhibitor.
Hypersensitivity
TLR4 upregulates CBS expression through NF-?B activation in a rat model of irritable bowel syndrome with chronic visceral hypersensitivity.
Hypersensitivity
[Anti-allergic effects of (E)-3-[p-(1H-imidazol-1-lylmethyl) phenyl]-2-propenoic acid (OKY-046), a specific thromboxane (TX) A2 synthetase inhibitor: effects on type I allergic reactions]
Hypersensitivity
[Anti-allergic effects of (E)-3-[p-(1H-imidazol-1-ylmethyl)phenyl]-2-propenoic acid (OKY-046), a specific thromboxane (TX) A2 synthetase inhibitor: effect of OKY-046 on II-IV type allergic reactions]
Hypersensitivity
[Effects of a specific thromboxane A2 synthetase inhibitor on lymphocyte and neutrophil functions in adult intractable asthmatics]
Hypersensitivity
[Pathogenetic investigations on a case of mauriac syndrome (author's transl)]
Hypertension
Changes in renal and systemic hemodynamics after NO-synthase inhibition in males with family history of hypertension.
Hypertension
Delay of the initiation of hypertension in spontaneously hypertensive rats by CV-4151, a specific thromboxane A2 synthetase inhibitor.
Hypertension
Role of the prostaglandin-thromboxane system in the development and maintenance of spontaneous hypertension in the rat.
Hypertension
Thromboxane A2 synthetase inhibition suppresses cough induced by angiotensin converting enzyme inhibitors.
Hypertension
Vascular endothelium dysfunction: a conservative target in metabolic disorders.
Hypertension
[Effect of calcium pantothenate on vitamin B6 and C correlation in patients with hypertension and ischemic heart disease]
Hypertension, Pregnancy-Induced
Comparative study of prostaglandin I2 (PG I2) and thromboxane A2 (TXA2) synthetase inhibitor (OKY-1581) on hemodynamics in pregnant dogs.
Hypertension, Pulmonary
Prevention of endotoxin-induced pulmonary hypertension in primates by the use of a selective thromboxane synthetase inhibitor, OKY 1581.
Hyperthyroidism
Amelioration of some metabolic effects produced by hyperthyroidism in late pregnant rats and their fetuses. Effects on lipids and proteins.
Hyperthyroidism
Effect of hyperthyroidism on lipogenesis in brown adipose tissue of young rats.
Hyperthyroidism
Effect of thyroid hormones on microsomal fatty acid chain elongation synthesis in rat liver.
Hyperthyroidism
Effects of experimental hypo- and hyperthyroidism on hepatic long-chain fatty acyl-CoA synthetase and hydrolase.
Hyperthyroidism
Glycogen and glycogen enzymes in the liver and striated muscle of rats under altered thyroid states.
Hyperthyroidism
Interaction between insulin and thyroid hormones on the control of carbohydrate and lipid metabolism in rat adipose tissue.
Hypertriglyceridemia
Effects of dietary fructose or glucose on triglyceride production and lipogenic enzyme activities in the liver of Wistar fatty rats, an animal model of NIDDM.
Hypertriglyceridemia
Pathogenesis of obesity by food restriction in OLETF rats-increased intestinal monoacylglycerol acyltransferase activities may be a crucial factor.
Hypobetalipoproteinemias
Current state of knowledge in Chorea-Acanthocytosis as core Neuroacanthocytosis syndrome.
Hypoglycemia
Effect of starvation and insulin-induced hypoglycemia on oxidative stress scavenger system and electron transport chain complexes from rat brain, liver, and kidney.
Hypoglycemia
Low intakes of carotene, vitamin?B2 , pantothenate and calcium predict cognitive decline among elderly patients with diabetes mellitus: The Japanese Elderly Diabetes Intervention Trial.
Hypoglycemia
SYMPTOMATIC HYPOGLYCEMIA, VISCERAL FATTY METAMORPHOSIS, AND AGLYCOGENOSIS IN AN INFANT LACKING GLYCOGEN SYNTHETASE AND PHOSPHORYLAS.
Hypoglycemia
[Hepatic glycogen synthetase deficiency or glycogen storage disease-zero. Mild phenotype with partial enzymatic defect]
Hypotension
Comparison between vascular plasminogen activator activity and changes in blood flow in the renal cortex in pigs.
Hypotension
Effects of inhibitors of poly(ADP-ribose) synthetase activity on hypotension and multiple organ dysfunction caused by endotoxin.
Hypothyroidism
Effects of experimental hypo- and hyperthyroidism on hepatic long-chain fatty acyl-CoA synthetase and hydrolase.
Hypothyroidism
Glycogen and glycogen enzymes in the liver and striated muscle of rats under altered thyroid states.
Hypothyroidism
Interaction between insulin and thyroid hormones on the control of carbohydrate and lipid metabolism in rat adipose tissue.
hypoxanthine phosphoribosyltransferase deficiency
Disorders associated with purine and pyrimidine metabolism.
hypoxanthine phosphoribosyltransferase deficiency
Kinetic aspects of purine metabolism in cultured fibroblasts. A comparative study of cells from patients overproducing purines due to HGPRT deficiency and PRPP synthetase superactivity.
hypoxanthine phosphoribosyltransferase deficiency
Mechanisms of accelerated purine nucleotide synthesis in human fibroblasts with superactive phosphoribosylpyrophosphate synthetases.
hypoxanthine phosphoribosyltransferase deficiency
Patterns of phosphoribosylpyrophosphate and ribose-5-phosphate concentration and generation in fibroblasts from patients with gout and purine overproduction.
hypoxanthine phosphoribosyltransferase deficiency
Purine synthesis during amino acid starvation of lymphoblasts with HPRT deficiency or PP-ribose-P synthetase overactivity decreases less than in normal cells.
hypoxanthine phosphoribosyltransferase deficiency
Use of intact erythrocytes in the diagnosis of inherited purine and pyrimidine disorders.
Idiopathic Interstitial Pneumonias
Clinical characteristics of patients with anti-aminoacyl-tRNA synthetase antibody positive idiopathic interstitial pneumonia.
Idiopathic Pulmonary Fibrosis
Clinical characteristics of interstitial lung diseases positive to different anti-synthetase antibodies.
Idiopathic Pulmonary Fibrosis
Oligo-2',5'-adenylate synthetase in pulmonary sarcoidosis and idiopathic pulmonary fibrosis.
Infections
2',5' oligoadenylate synthetase activity in bovine peripheral blood mononuclear cells following bovine herpesvirus type-1-induced respiratory disease: a prognostic indicator?
Infections
2',5'-Oligoadenylate synthetase 1(OAS1) inhibits PRRSV replication in Marc-145 cells.
Infections
2',5'-Oligoadenylate synthetase and interferon in peripheral blood after rubella, measles, or mumps live virus vaccine.
Infections
Activation of senescence-associated Dark-inducible (DIN) genes during infection contributes to enhanced susceptibility to plant viruses.
Infections
Adenovirus-mediated gene transfer of interferon alpha inhibits hepatitis C virus replication in hepatocytes.
Infections
Alteration of nuclear (2'-5')oligoriboadenylate synthetase and nuclease activities preceding replication of human immunodeficiency virus in H9 cells.
Infections
An immunoproteomic approach for identification of clinical biomarkers for monitoring disease: application to cystic fibrosis.
Infections
Assessing gene expression during pathogenesis: Use of qRT-PCR to follow toxin production in the entomopathogenic fungus Beauveria bassiana during infection and immune response of the insect host Triatoma infestans.
Infections
Bimodular Peptide Synthetase SidE Produces Fumarylalanine in the Human Pathogen Aspergillus fumigatus.
Infections
Binding of mammalian ribosomes to MS2 phage RNA reveals an overlapping gene encoding a lysis function.
Infections
Biochemical analysis of mutants of a macrophage cell line resistant to the growth-inhibitory activity of interferon.
Infections
Comparative evaluation of permissiveness to dengue virus serotype 2 infection in primary rodent macrophages.
Infections
Contribution of MX dynamin, oligoadenylate synthetase, and protein kinase R to anti-paramyxovirus activity of type 1 interferons in vitro.
Infections
Could 2'5'-oligoadenylate synthetase isoforms be biomarkers to differentiate between disease flare and infection in lupus patients? A pilot study.
Infections
Current progress in proteomic study of hepatitis C virus-related human hepatocellular carcinoma.
Infections
Detection of elevated levels of 2-5A synthetase in serum from children with various infectious diseases.
Infections
Development of DNA mismatch repair gene, MutS, as a diagnostic marker for detection and phylogenetic analysis of algal Megaviruses.
Infections
Discovery of novel tRNA-amino acid dual-site inhibitors against threonyl-tRNA synthetase by fragment-based target hopping.
Infections
Disposition and Metabolism of GSK2251052 in Humans: A Novel Boron-containing Antibiotic.
Infections
Evidence for a deficiency of interferon response in mononuclear cells from hepatitis C viremic patients.
Infections
Expression of interferon inducible genes following Hantaan virus infection as a mechanism of resistance in A549 cells.
Infections
Expression of pathogenesis-related genes in Metarhizium anisopliae when infecting Spodoptera exigua
Infections
Genomics-Driven Discovery of Phytotoxic Cytochalasans Involved in the Virulence of the Wheat Pathogen Parastagonospora nodorum.
Infections
Glycogen synthetase kinase 3 inhibition drives MIC-A/B to promote cytokine production by human natural killer cells in Dengue virus type 2 infection.
Infections
Hepatic carbamyl phosphate synthetase and ornithine transcarbamylase in mouse influenze A and influenze B infection.
Infections
Host responses to Plasmodium yoelii hepatic stages: a paradigm in host-parasite interaction.
Infections
Human respiratory syncytial virus infection is inhibited by IFN-induced transmembrane proteins.
Infections
Identification of bacteriophage T4D gene 29 product, a baseplate hub component, as a folylpolyglutamate synthetase.
Infections
Immunization with recombinant Lactobacillus casei strains producing K99, K88 fimbrial protein protects mice against enterotoxigenic Escherichia coli.
Infections
Immunogenicity and protective efficacy of orally or intranasally administered recombinant Lactobacillus casei expressing ETEC K99.
Infections
Immunoregulation during acute infection with Epstein-Barr virus: dynamics of interferon and 2',5'-oligoadenylate synthetase activity.
Infections
In Vitro Analysis of Metabolites Secreted during Infection of Lung Epithelial Cells by Cryptococcus neoformans.
Infections
Induction of 2',5' oligo(A) synthetase in tumor-bearing mice with encephalomyocarditis (EMC) virus or poly(I)poly(C).
Infections
Induction of immune responses in mice after oral immunization with recombinant Lactobacillus casei strains expressing enterotoxigenic Escherichia coli F41 fimbrial protein.
Infections
Infection with Moloney murine sarcoma virus inhibits myogenesis and alters the myogenic-associated (2'-5')oligoadenylate synthetase expression and activity.
Infections
Interferon regulatory factor 4 contributes to transformation of v-Rel-expressing fibroblasts.
Infections
Isolation of Beauveria bassiana from the Chagas Disease Vector Triatoma infestans in the Gran Chaco Region of Argentina: Assessment of Gene Expression during Host-Pathogen Interaction.
Infections
Mode of action of the anti-AIDS compound poly(I).poly(C12U) (Ampligen): activator of 2',5'-oligoadenylate synthetase and double-stranded RNA-dependent kinase.
Infections
Modeling the Role of Lanthionine Synthetase C-Like 2 (LANCL2) in the Modulation of Immune Responses to Helicobacter pylori Infection.
Infections
Modulation of nuclear matrix-associated 2',5'-oligoadenylate metabolism and ribonuclease L activity in H9 cells by human immunodeficiency virus.
Infections
Molecular cloning and bioinformatic analysis of the Streptococcus agalactiae neuA gene isolated from tilapia.
Infections
Oligoadenylate synthetase 3 S381R gene polymorphism is associated with severity of EV71 infection in Chinese children.
Infections
Phosphoribosylpyrophosphate synthetase superactivity and recurrent infections is caused by a p.Val142Leu mutation in PRS-I.
Infections
Physcomitrella patens auxin conjugate synthetase (GH3) double knockout mutants are more resistant to Pythium infection than wild type.
Infections
Porcine 2', 5'-oligoadenylate synthetase 2 inhibits porcine reproductive and respiratory syndrome virus replication in vitro.
Infections
Protection of HeLa-T4+ cells against human immunodeficiency virus (HIV) infection after stable transfection with HIV LTR-2',5'-oligoadenylate synthetase hybrid gene.
Infections
Protein-protein interactions involving T4 phage-coded deoxycytidylate deaminase and thymidylate synthase.
Infections
Purification and properties of T4 phage thymidylate synthetase produced by the cloned gene in an amplification vector.
Infections
Relationship Between the Quorum Network (Sensing/Quenching) and Clinical Features of Pneumonia and Bacteraemia Caused by A. baumannii.
Infections
Role of chicken melanoma differentiation-associated gene 5 in induction and activation of innate and adaptive immune responses to infectious bursal disease virus in cultured macrophages.
Infections
Signature-tagged and directed mutagenesis identify PABA synthetase as essential for Aspergillus fumigatus pathogenicity.
Infections
Simultaneous initiation of synthesis of bacteriophage T4 DNA and of deoxyribonucleotides.
Infections
Status of urea and related enzymes during Plasmodium yoelii infection and pyrimethamine treatment in mice.
Infections
T4 phage gene 32 protein as a candidate organizing factor for the deoxyribonucleoside triphosphate synthetase complex.
Infections
Tandem cloning of bacteriophage T4 nrdA and nrdB genes and overproduction of ribonucleoside diphosphate reductase (alpha 2 beta 2) and a mutationally altered form (alpha 2 beta 2(93)).
Infections
The C/EBPbeta isoform 34-kDa LAP is responsible for NF-IL-6-mediated gene induction in activated macrophages, but is not essential for intracellular bacteria killing.
Infections
The clinical trial of streptomycin pantothenate in the treatment of soft tissue infections.
Infections
The effect of pantothenate deficiency on Trypanosoma lewisi infection in the rat.
Infections
The Yersinia pestis siderophore, yersiniabactin, and the ZnuABC system both contribute to zinc acquisition and the development of lethal septicaemic plague in mice.
Infections
Time course of interferon levels, antiviral state, 2',5'-oligoadenylate synthetase and side effects in healthy men.
Infections
Transcriptome analysis of Enterococcus faecalis during mammalian infection shows cells undergo adaptation and exist in a stringent response state.
Infections
[Immune response against Chlamydia trachomatis inoculation in mice--changes in interferon activity, antibody titers and weight of the spleen as parameters of infection]
Infections
[The chloramphenicol-calcium pantothenate complex in stubborn infections of the urinary tract.]
Infections
[Urinary protein detection by iTRAQ® associated with renal transplant complications and its modification with therapy].
Infectious Mononucleosis
Immunoregulation during acute infection with Epstein-Barr virus: dynamics of interferon and 2',5'-oligoadenylate synthetase activity.
Inflammatory Bowel Diseases
(2'-5') oligo adenylate synthetase activity in leucocytes of patients with inflammatory bowel disease.
Inflammatory Bowel Diseases
(2'-5')Oligoadenylate synthetase activity in intestinal mononuclear and epithelial cells of inflammatory bowel disease patients.
Inflammatory Bowel Diseases
An N,N-Bis(benzimidazolylpicolinoyl)piperazine (BT-11): A Novel Lanthionine Synthetase C-Like 2-Based Therapeutic for Inflammatory Bowel Disease.
Inflammatory Bowel Diseases
Interferon inhibits prostaglandin E2 synthesis and stimulates (2'-5')oligoadenylate synthetase activity in peripheral blood mononuclear cells of inflammatory bowel disease patients.
Inflammatory Bowel Diseases
Modeling new immunoregulatory therapeutics as antimicrobial alternatives for treating Clostridium difficile infection.
Inflammatory Bowel Diseases
Mucosal glucosamine synthetase activity in inflammatory bowel disease.
Inflammatory Bowel Diseases
Nonclinical Toxicology and Toxicokinetic Profile of an Oral Lanthionine Synthetase C-Like 2 (LANCL2) Agonist, BT-11.
Inflammatory Bowel Diseases
The Safety, Tolerability, and Pharmacokinetics Profile of BT-11, an Oral, Gut-Restricted Lanthionine Synthetase C-Like 2 Agonist Investigational New Drug for Inflammatory Bowel Disease: A Randomized, Double-Blind, Placebo-Controlled Phase I Clinical Trial.
Influenza, Human
Hepatic carbamyl phosphate synthetase and ornithine transcarbamylase in mouse influenze A and influenze B infection.
Influenza, Human
Lanthionine Synthetase C-Like 2 Modulates Immune Responses to Influenza Virus Infection.
Influenza, Human
Molecular pathogenesis of influenza A virus infection and virus-induced regulation of cytokine gene expression.
Influenza, Human
[Clinical trials of recombinant gamma-interferon. Circulating interferon and the 2,5-oligoadenylate synthetase activity after intramuscular and inhalation administrations]
Insulin Resistance
Abdominal obesity is associated with insulin resistance and reduced glycogen synthetase activity in skeletal muscle.
Insulin Resistance
Acyl CoA synthetase 5 (ACSL5) ablation in mice increases energy expenditure and insulin sensitivity and delays fat absorption.
Insulin Resistance
AMPK in the small intestine in normal and pathophysiological conditions.
Insulin Resistance
Diminished activities of fatty acid synthesis enzymes in insulin-resistant adipocytes from spontaneously obese rats.
Insulin Resistance
Elevated PC-1 content in cultured skin fibroblasts correlates with decreased in vivo and in vitro insulin action in nondiabetic subjects: evidence that PC-1 may be an intrinsic factor in impaired insulin receptor signaling.
Insulin Resistance
Endocytosis of insulin receptors is not required for activation or deactivation of the hormone response.
Insulin Resistance
Genistein reduced insulin resistance index through modulating lipid metabolism in ovariectomized rats.
Insulin Resistance
Insulin resistance, a result of reduced synthesis of prostaglandylinositol cyclic phosphate, a mediator of insulin action? Regulation of cyclic PIP synthetase activity by oral antidiabetic and antihypertensive drugs.
Insulinoma
LANCL2 is necessary for abscisic acid binding and signaling in human granulocytes and in rat insulinoma cells.
Insulinoma
Molecular modeling of lanthionine synthetase component C-like protein 2: a potential target for the discovery of novel type 2 diabetes prophylactics and therapeutics.
Insulinoma
Poly(ADP-ribose) synthetase inhibitors enhance streptozotocin-induced killing of insulinoma cells by inhibiting the repair of DNA strand breaks.
Intellectual Disability
A patient with pantothenate kinase-associated neurodegeneration and supranuclear gaze palsy.
Intellectual Disability
[Hepatic glycogen synthetase deficiency or glycogen storage disease-zero. Mild phenotype with partial enzymatic defect]
Intervertebral Disc Displacement
Roles of thromboxane A2 and leukotriene B4 in radicular pain induced by herniated nucleus pulposus.
Intestinal Polyposis
Suppression of intestinal polyposis in Apcmin/+ mice by targeting the nitric oxide or poly(ADP-ribose) pathways.
Intestinal Volvulus
Characterization of a possible tRNA synthetase gene from Onchocerca volvulus.
Iron Deficiencies
Bio-inorganic regulation of pathways of carbohydrate and lipid metabolism. II. The effect of iron-deficiency on the profile of enzymes in the developing rat adrenal gland.
Iron Deficiencies
Pyrimidine 5'nucleotidase and several other red cell enzyme activities in beta-thalassaemia trait.
Joint Diseases
Degenerative knee joint disease in mice lacking 3'-phosphoadenosine 5'-phosphosulfate synthetase 2 (Papss2) activity: a putative model of human PAPSS2 deficiency-associated arthrosis.
Joint Diseases
Distinct arthropathies of the hands in patients with anti-aminoacyl tRNA synthetase antibodies: usefulness of autoantibody profiles in classifying patients.
Keratitis
Recessive Mutation in a Nuclear-Encoded Mitochondrial tRNA Synthetase Associated With Infantile Cataract, Congenital Neurotrophic Keratitis, and Orbital Myopathy.
Kernicterus
Magnetic resonance imaging pattern recognition in childhood bilateral basal ganglia disorders.
Ketosis
Effect of ketogenic diets in gestation on some characteristics of carbohydrate metabolism in fetal pig brain and liver.
Kidney Neoplasms
In vivo and in vitro induction of (2'-5') oligoadenylate synthetase by human interferons in leukocytes from healthy donors and patients with renal cancer and hairy cell leukemia.
Leigh Disease
Confirmation of CAGSSS syndrome as a distinct entity in a Danish patient with a novel homozygous mutation in IARS2.
Leigh Disease
Fulminant Leigh syndrome and sudden unexpected death in a family with the T9176C mutation of the mitochondrial ATPase 6 gene.
Lesch-Nyhan Syndrome
Kinetic aspects of purine metabolism in cultured fibroblasts. A comparative study of cells from patients overproducing purines due to HGPRT deficiency and PRPP synthetase superactivity.
Lesch-Nyhan Syndrome
Lesch-Nyhan syndrome and its pathogenesis: normal nicotinamide-adenine dinucleotide but reduced ATP concentrations that correlate with reduced poly(ADP-ribose) synthetase activity in HPRT-deficient lymphoblasts.
Lesch-Nyhan Syndrome
Severe tongue protrusion dystonia: clinical syndromes and possible treatment.
Lesch-Nyhan Syndrome
Tongue Protrusion Dystonia in Pantothenate Kinase-Associated Neurodegeneration.
Lesch-Nyhan Syndrome
Use of intact erythrocytes in the diagnosis of inherited purine and pyrimidine disorders.
Leukemia
Action of interferon-alpha on hairy cell leukemia: expression of specific receptors and (2'-5')oligo (A) synthetase in tumor cells from sensitive and resistant patients.
Leukemia
Analysis of the TPA regulatory element in the genomic poly(ADP-ribose) synthetase gene in human leukemia U937 cells.
Leukemia
Apoptosis and interferons: role of interferon-stimulated genes as mediators of apoptosis.
Leukemia
Calcium ionophore treatment impairs the sterol-mediated suppression of 3-hydroxy-3-methylglutaryl-coenzyme A reductase, 3-hydroxy-3-methylglutaryl-coenzyme A synthase, and farnesyl diphosphate synthetase.
Leukemia
Combined effects of interferon and 2'-deoxycoformycin on 2',5'-oligoadenylate synthetase and adenosine deaminase in hairy cell and chronic lymphocytic leukemia cells.
Leukemia
Decrease of oligo-2',5'-adenylate synthetase activity in BALB3T3 cell persistently infected with Moloney murine leukemia virus.
Leukemia
Effects of interferon-alpha (IFN) on the expression of interleukin 1-beta (IL-1), interleukin 6 (IL-6), granulocyte-macrophage colony-stimulating factor (GM-CSF) and tumor necrosis factor-alpha (TNF) in acute myeloid leukemia (AML) blasts.
Leukemia
Fluctuation of gene expression for poly(ADP-ribose) synthetase during hemin-induced erythroid differentiation of human leukemia K562 cells and its reversion process.
Leukemia
High expression of ganglioside alpha-2,8-sialyltransferase (GD3 synthase) gene in adult T-cell leukemia cells unrelated to the gene expression of human T-lymphotropic virus type I.
Leukemia
Immunological recovery and dose evaluation in IFN-alpha treatment of hairy cell leukemia: analysis of leukocyte differentiation antigens, NK and 2',5'-oligoadenylate synthetase activity.
Leukemia
In vivo and in vitro induction of (2'-5') oligoadenylate synthetase by human interferons in leukocytes from healthy donors and patients with renal cancer and hairy cell leukemia.
Leukemia
Increased levels of interferon-induced (2'--5') oligo-isoadenylate synthetase in mature T-lymphocytes and in differentiated Friend-erythroleukemic cells.
Leukemia
Infection with Moloney murine sarcoma virus inhibits myogenesis and alters the myogenic-associated (2'-5')oligoadenylate synthetase expression and activity.
Leukemia
Inhibition of interferon-gamma- and phorbol ester-induced HLA-DR and interleukin-1 production by the expression of a transfected poly(ADP-ribose) synthetase gene in human leukemia THP-1 cells.
Leukemia
Inhibition of the leukotriene synthetase of rat basophil leukemia cells by diethylcarbamazine, and synergism between diethylcarbamazine and piriprost, a 5-lipoxygenase inhibitor.
Leukemia
Isolation and characterization of interferon-resistant variants from S49 mouse lymphoma.
Leukemia
Lack of genotoxic and cytotoxic effects of the herbicide lenacil on mouse tumor cells and on some Salmonella typhimurium strains.
Leukemia
Leukemia inhibitory factor induces nociceptin mRNA in cultured rat cortical neurons.
Leukemia
Leukotriene C synthetase, a special glutathione S-transferase: properties of the enzyme and inhibitor studies with special reference to the mode of action of U-60,257, a selective inhibitor of leukotriene synthesis.
Leukemia
Maturation of human promyelocytic leukemia cells induced by nicotinamide: evidence of a regulatory role for ADP-ribosylation of chromosomal proteins.
Leukemia
Protein binding to the interferon response enhancer correlates with interferon induction of 2'-5'-oligoadenylate synthetase in normal and interferon-resistant Friend cells.
Leukemia
Purification, characterization, and structural properties of a single protein from rat basophilic leukemia (RBL-1) cells possessing 5-lipoxygenase and leukotriene A4 synthetase activities.
Leukemia
Response of L-1210 tumor in mice toward treatment with interferon or poly(I) X poly(C).
Leukemia
Retinoic acid enhances the expression of interferon-induced proteins: evidence for multiple mechanisms of action.
Leukemia
Role of thymidine kinase and thymidylate synthetase in the cytostatic, antimetabolic, and antitumor effects of the carbocyclic analogue of 5-nitro-2'-deoxyuridine. A comparison with 5-nitro-2'-deoxyuridine.
Leukemia
Subcellular distribution of 2',5'-oligoadenylate synthetase in differentiating Friend leukemia cells.
Leukemia
Variation of (2'-5') oligo A synthetase level in lymphocytes and granulocytes of patients with viral infections and leukemia.
Leukemia L1210
5-Substituted 2'-deoxyuridines: correlation between inhibition of tumor cell growth and inhibition of thymidine kinase and thymidylate synthetase.
Leukemia, Eosinophilic, Acute
Fusion of TEL/ETV6 to a novel ACS2 in myelodysplastic syndrome and acute myelogenous leukemia with t(5;12)(q31;p13).
Leukemia, Erythroblastic, Acute
2',5'-Oligoadenylate synthetase-uninducible alpha/beta-interferon-resistant Friend cells develop an antiviral state when permeabilized with lysolecithin and treated with 2',5'-oligoadenylate oligomers.
Leukemia, Erythroblastic, Acute
Comparison of the acyl chain specificities of human myristoyl-CoA synthetase and human myristoyl-CoA:protein N-myristoyltransferase.
Leukemia, Erythroblastic, Acute
Interferon-independent activation of (2'-5') oligoadenylate synthetase in Friend erythroleukemia cell variants exposed to HMBA.
Leukemia, Erythroblastic, Acute
Isolation and electron microscopic characterization of the high molecular mass aminoacyl-tRNA synthetase complex from murine erythroleukemia cells.
Leukemia, Hairy Cell
Action of interferon-alpha on hairy cell leukemia: expression of specific receptors and (2'-5')oligo (A) synthetase in tumor cells from sensitive and resistant patients.
Leukemia, Hairy Cell
Combined effects of interferon and 2'-deoxycoformycin on 2',5'-oligoadenylate synthetase and adenosine deaminase in hairy cell and chronic lymphocytic leukemia cells.
Leukemia, Hairy Cell
Effects of interferon-alpha (IFN) on the expression of interleukin 1-beta (IL-1), interleukin 6 (IL-6), granulocyte-macrophage colony-stimulating factor (GM-CSF) and tumor necrosis factor-alpha (TNF) in acute myeloid leukemia (AML) blasts.
Leukemia, Hairy Cell
Immunological recovery and dose evaluation in IFN-alpha treatment of hairy cell leukemia: analysis of leukocyte differentiation antigens, NK and 2',5'-oligoadenylate synthetase activity.
Leukemia, Hairy Cell
In vivo and in vitro induction of (2'-5') oligoadenylate synthetase by human interferons in leukocytes from healthy donors and patients with renal cancer and hairy cell leukemia.
Leukemia, Lymphocytic, Chronic, B-Cell
Combined effects of interferon and 2'-deoxycoformycin on 2',5'-oligoadenylate synthetase and adenosine deaminase in hairy cell and chronic lymphocytic leukemia cells.
Leukemia, Lymphocytic, Chronic, B-Cell
Effects of interferon-alpha (IFN) on the expression of interleukin 1-beta (IL-1), interleukin 6 (IL-6), granulocyte-macrophage colony-stimulating factor (GM-CSF) and tumor necrosis factor-alpha (TNF) in acute myeloid leukemia (AML) blasts.
Leukemia, Lymphocytic, Chronic, B-Cell
Increased levels of interferon-induced (2'--5') oligo-isoadenylate synthetase in mature T-lymphocytes and in differentiated Friend-erythroleukemic cells.
Leukemia, Lymphocytic, Chronic, B-Cell
miR-15a and miR-16-1 down-regulation in pituitary adenomas.
Leukemia, Lymphocytic, Chronic, B-Cell
Serum levels of 2',5 oligoadenylate synthetase during interferon therapy in patients with B-cell chronic lymphocytic leukemia.
Leukemia, Lymphoid
Eight genes are highly associated with BMD variation in postmenopausal Caucasian women.
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Analysis of interferon-inducible genes in cells of chronic myeloid leukemia patients responsive or resistant to an interferon-alpha treatment.
Leukemia, Myeloid
Expression of a gene encoding a tRNA synthetase-like protein is enhanced in tumorigenic human myeloid leukemia cells and is cell cycle stage- and differentiation-dependent.
Leukemia, Myeloid, Acute
Fusion of TEL/ETV6 to a novel ACS2 in myelodysplastic syndrome and acute myelogenous leukemia with t(5;12)(q31;p13).
Leukoencephalopathies
AARS2 leukoencephalopathy: A new variant of mitochondrial encephalomyopathy.
Leukoencephalopathies
An adolescence-onset male leukoencephalopathy with remarkable cerebellar atrophy and novel compound heterozygous AARS2 gene mutations: a case report.
Leukoencephalopathies
Biallelic KARS pathogenic variants cause an early-onset progressive leukodystrophy.
Leukoencephalopathies
Early-Onset Mild Type Leukoencephalopathy Caused by a Homozygous EARS2 Mutation.
Leukoencephalopathies
Mutations of POLR3A Encoding a Catalytic Subunit of RNA Polymerase Pol III Cause a Recessive Hypomyelinating Leukodystrophy.
Liver Cirrhosis
Aminoacyl-tRNA synthetase interacting multi-functional protein 1 attenuates liver fibrosis by inhibiting TGF? signaling.
Liver Cirrhosis
Serum levels of soluble interferon Alfa/Beta receptor as an inhibitory factor of interferon in the patients with chronic hepatitis C.
Liver Diseases
Evidence for a deficiency of interferon production in patients with chronic hepatitis B virus infection acquired in adult life.
Liver Diseases
Identification of a mutation in LARS as a novel cause of infantile hepatopathy.
Liver Diseases
Inability of chronic alcoholics with liver disease to use food as a source of folates, thiamin and vitamin B6.
Liver Diseases
Lack of in vivo activation of the interferon system in HBsAg-positive chronic active hepatitis.
Liver Diseases
Mx1, OAS1 and OAS2 polymorphisms are associated with the severity of liver disease in HIV/HCV-coinfected patients: A cross-sectional study.
Liver Diseases
Serum Metabolomics Reveals ?-Glutamyl Dipeptides as Biomarkers for Discrimination among Different Forms of Liver Disease.
Liver Diseases, Alcoholic
S-Adenosyl-L-methionine and alcoholic liver disease in animal models: implications for early intervention in human beings.
Liver Failure
Deep phenotyping of MARS1 (interstitial lung and liver disease) and LARS1 (infantile liver failure syndrome 1) recessive multisystemic disease using Human Phenotype Ontology annotation: Overlap and differences. Case report and review of literature.
Liver Failure
Severe Neonatal Manifestations of Infantile Liver Failure Syndrome Type 1 Caused by Cytosolic Leucine-tRNA Synthetase Deficiency.
Liver Neoplasms
Regression of hepatocellular cancer in a patient treated with arginine deiminase.
Liver Neoplasms
[Characteristics of gene expression of adrenal cortical steroid synthetase and its regulatory factor in mice with H22 liver cancer of different patterns].
Liver Neoplasms, Experimental
Inhibition of 5-phosphoribosyl-1-pyrophosphate synthetase by the monophosphate metabolite of 4-amino-8-(beta-D-ribofuranosylamino)pyrimido[5,4-d]pyrimidine: a novel mechanism for antitumor activity.
Liver Neoplasms, Experimental
Substrate and hormone regulation of palmitoyl-CoA synthetase in 7800 C1 Morris hepatoma cells and cultured rat hepatocytes.
long-chain acyl-coa dehydrogenase deficiency
Altered Metabolic Flexibility in Inherited Metabolic Diseases of Mitochondrial Fatty Acid Metabolism.
Lung Diseases
Bi-allelic Mutations in Phe-tRNA Synthetase Associated with a Multi-system Pulmonary Disease Support Non-translational Function.
Lung Diseases
Clinicoserological features of antisynthetase syndrome (ASyS)-associated interstitial lung disease presenting to respiratory services: comparison with idiopathic pulmonary fibrosis and ASyS diagnosed in rheumatology services.
Lung Diseases, Interstitial
A case of anti-aminoacyl tRNA synthetase (ARS) antibody-positive polymyositis (PM)/dermatomyositis (DM)-associated interstitial pneumonia (IP) successfully controlled with bosentan therapy.
Lung Diseases, Interstitial
A case of interstitial lung disease with anti-EJ and anti-CCP antibodies preceding rheumatoid arthritis.
Lung Diseases, Interstitial
A new approach to the classification of idiopathic inflammatory myopathy: myositis-specific autoantibodies define useful homogeneous patient groups.
Lung Diseases, Interstitial
A woman with anti-histidyl-aminoacyl-tRNA synthetase (Jo-1 antibodies), myositis, hyperglycemia, interstitial lung disease, and morbilliform rashes.
Lung Diseases, Interstitial
Acute Onset Anti-Synthetase Syndrome With Pericardial Effusion and Non-Specific Interstitial Pneumonia.
Lung Diseases, Interstitial
Acute respiratory distress syndrome secondary to antisynthetase syndrome is reversible with tacrolimus.
Lung Diseases, Interstitial
Anti-aminoacyl-tRNA synthetase antibodies in clinical course prediction of interstitial lung disease complicated with idiopathic inflammatory myopathies.
Lung Diseases, Interstitial
Anti-glycyl tRNA synthetase antibody associated interstitial lung disease without symptoms of polymyositis/dermatomyositis.
Lung Diseases, Interstitial
Anti-Ro52 antibodies, antisynthetase antibodies, and antisynthetase syndrome.
Lung Diseases, Interstitial
Anti-Ro52 autoantibodies are associated with interstitial lung disease and more severe disease in patients with juvenile myositis.
Lung Diseases, Interstitial
Anti-tRNA synthetase syndrome interstitial lung disease: A single center experience.
Lung Diseases, Interstitial
Antisynthetase syndrome presenting as rheumatoid-like polyarthritis.
Lung Diseases, Interstitial
Antisynthetase syndrome: An under-recognized cause of interstitial lung disease.
Lung Diseases, Interstitial
Autoantibodies to glycyl-transfer RNA synthetase in myositis. Association with dermatomyositis and immunologic heterogeneity.
Lung Diseases, Interstitial
Biomarkers and Autoantibodies of Interstitial Lung Disease with Idiopathic Inflammatory Myopathies.
Lung Diseases, Interstitial
Clinical and immunogenetic features of patients with autoantibodies to asparaginyl-transfer RNA synthetase.
Lung Diseases, Interstitial
Clinical and pathological findings of interstitial lung disease patients with anti-aminoacyl-tRNA synthetase autoantibodies.
Lung Diseases, Interstitial
Clinical characteristics of interstitial lung diseases positive to different anti-synthetase antibodies.
Lung Diseases, Interstitial
Clinical characteristics of patients with anti-aminoacyl-tRNA synthetase antibody positive idiopathic interstitial pneumonia.
Lung Diseases, Interstitial
Clinical manifestations in patients with antibody to PL-12 antigen (alanyl-tRNA synthetase).
Lung Diseases, Interstitial
Clinical manifestations of skin, lung and muscle diseases in dermatomyositis positive for anti-aminoacyl tRNA synthetase antibodies.
Lung Diseases, Interstitial
Clinical significance and new detection system of autoantibodies in myositis with interstitial lung disease.
Lung Diseases, Interstitial
Clinical significance of anti-histidyl-tRNA synthetase (Jo1) autoantibodies.
Lung Diseases, Interstitial
Clinical significance of radiological patterns of HRCT and their association with macrophage activation in dermatomyositis.
Lung Diseases, Interstitial
Clinical, radiological, and pathological features of anti-asparaginyl tRNA synthetase antibody-related interstitial lung disease.
Lung Diseases, Interstitial
Comparison of anti-aminoacyl-tRNA synthetase antibody-related and idiopathic non-specific interstitial pneumonia.
Lung Diseases, Interstitial
Comparison of long-term prognosis and relapse of dermatomyositis complicated with interstitial pneumonia according to autoantibodies: anti-aminoacyl tRNA synthetase antibodies versus anti-melanoma differentiation-associated gene 5 antibody.
Lung Diseases, Interstitial
Comparison of Pulmonary Involvement Between Patients Expressing Anti-PL-7 and Anti-Jo-1 Antibodies.
Lung Diseases, Interstitial
Correlation of Antisynthetase Antibody Levels with Disease Course in a Patient with Interstitial Lung Disease and Elevated Muscle Enzymes.
Lung Diseases, Interstitial
Dermatomyositis: an association of gingival telangiectases and anti Jo-1 antibody in the adult.
Lung Diseases, Interstitial
Development of antisynthetase syndrome in a patient with rheumatoid arthritis.
Lung Diseases, Interstitial
Efficacy of Glucocorticoids and Calcineurin Inhibitors for Anti-aminoacyl-tRNA Synthetase Antibody-positive Polymyositis/dermatomyositis-associated Interstitial Lung Disease: A Propensity Score-matched Analysis.
Lung Diseases, Interstitial
Elevated serum B-cell activating factor levels in patients with dermatomyositis: Association with interstitial lung disease.
Lung Diseases, Interstitial
Establishment of an ELISA to detect anti-glycyl-tRNA synthetase antibody (anti-EJ), a serological marker of dermatomyositis/polymyositis and interstitial lung disease.
Lung Diseases, Interstitial
HLA-DRB1*0101/*0405 is associated with susceptibility to Anti-MDA5 antibody-positive dermatomyositis in the Japanese population.
Lung Diseases, Interstitial
Interstitial lung disease associated with anti-PM/Scl or anti-aminoacyl-tRNA synthetase autoantibodies: a similar condition?
Lung Diseases, Interstitial
Involvement of NK Cells and NKp30 Pathway in Antisynthetase Syndrome.
Lung Diseases, Interstitial
Long-term clinical course of anti-glycyl tRNA synthetase (anti-EJ) antibody-related interstitial lung disease pathologically proven by surgical lung biopsy.
Lung Diseases, Interstitial
Nivolumab-induced anti-aminoacyl-tRNA synthetase antibody-positive polymyositis complicated by interstitial pneumonia in a patient with lung adenocarcinoma.
Lung Diseases, Interstitial
Oxygen-Dependent Patient with Antisynthetase Syndrome Associated Interstitial Lung Disease Responds Promptly to Rituximab with Rapid Pulmonary Function Improvement.
Lung Diseases, Interstitial
Patients with anti-Jo1 antibodies display a characteristic IgG Fc-glycan profile which is further enhanced in anti-Jo1 autoantibodies.
Lung Diseases, Interstitial
Plasma homocysteine levels are positively associated with interstitial lung disease in dermatomyositis patients with anti-aminoacyl-tRNA synthetase antibody.
Lung Diseases, Interstitial
Potential of Krebs von den Lungen-6 as a predictor of relapse in interstitial pneumonia with anti-aminoacyl tRNA synthetase antibodies-positive dermatomyositis.
Lung Diseases, Interstitial
Predictive Factors for the Long-Term Deterioration of Pulmonary Function in Interstitial Lung Disease Associated with Anti-Aminoacyl-tRNA Synthetase Antibodies.
Lung Diseases, Interstitial
Predictive factors for the recurrence of anti-aminoacyl-tRNA synthetase antibody-associated interstitial lung disease.
Lung Diseases, Interstitial
Prognosis of Interstitial Lung Disease Associated with Anti-Aminoacyl-tRNA Synthetase Antibodies: Look in the Middle.
Lung Diseases, Interstitial
Prognostic significance of anti-aminoacyl-tRNA synthetase antibodies in polymyositis/dermatomyositis-associated interstitial lung disease: a retrospective case control study.
Lung Diseases, Interstitial
Serial measurements of KL-6 for monitoring activity and recurrence of interstitial pneumonia with anti-aminoacyl-tRNA synthetase antibody: A retrospective cohort study.
Lung Diseases, Interstitial
Tacrolimus-induced diabetic ketoacidosis with subsequent rapid recovery of endogenous insulin secretion after cessation of tacrolimus: A case report with review of literature.
Lung Diseases, Interstitial
The Association of Anti-Aminoacyl-Transfer Ribonucleic Acid Synthetase Antibodies in Patients With Rheumatoid Arthritis and Interstitial Lung Disease.
Lung Diseases, Interstitial
The comparison of nailfold videocapillaroscopy findings between anti-melanoma differentiation-associated gene 5 antibody and anti-aminoacyl tRNA synthetase antibody in patients with dermatomyositis complicated by interstitial lung disease.
Lung Diseases, Interstitial
The long-term outcome of interstitial lung disease with anti-aminoacyl-tRNA synthetase antibodies.
Lung Diseases, Interstitial
The Onset of Eosinophilic Pneumonia Preceding Anti-synthetase Syndrome.
Lung Diseases, Interstitial
The pulmonary histopathologic manifestations of the anti-Jo-1 tRNA synthetase syndrome.
Lung Diseases, Interstitial
The relationship between type 1 IFN and vasculopathy in anti-MDA5 antibody-positive dermatomyositis patients.
Lung Diseases, Interstitial
Two cases with autoantibodies to small ubiquitin-like modifier activating enzyme: A potential unique subset of dermatomyositis-associated interstitial lung disease.
Lung Diseases, Interstitial
[Clinical and pathological findings of patients with interstitial lung disease associated with antisynthetase]
Lung Diseases, Interstitial
[Interstitial lung disease in patients with connective tissue diseases]
Lung Diseases, Interstitial
[Myositis-related interstitial lung disease and antisynthetase syndrome.]
Lung Diseases, Interstitial
[Progress of Autoantibody Examinations for Connective Tissue Diseases].
Lung Injury
Novel insights into phosgene-induced acute lung injury in rats: role of dysregulated cardiopulmonary reflexes and nitric oxide in lung edema pathogenesis.
Lung Injury
Rationally designed pure-inorganic upconversion nanoprobes for ultra-highly selective hydrogen sulfide imaging and elimination in vivo.
Lung Injury
Role of arachidonic acid metabolites in oleic acid induced pulmonary injury in a canine model. Effect of ketoconazole (thromboxane synthetase inhibitor).
Lung Neoplasms
2-Aminophenylpyrimidines as Novel Inhibitors of Aminoacyl-tRNA Synthetase Interacting Multifunctional Protein 2 (AIMP2)-DX2 for Lung Cancer Treatment.
Lung Neoplasms
A novel human tRNA-dihydrouridine synthase involved in pulmonary carcinogenesis.
Lung Neoplasms
Cell type-specific differences in metabolic activation of N-nitrosodiethylamine by human lung cancer cell lines.
Lung Neoplasms
IARS2 silencing induces non-small cell lung cancer cells proliferation inhibition, cell cycle arrest and promotes cell apoptosis.
Lung Neoplasms
Indomethacin-mediated enhancement of lymphocyte response to mitogens in healthy subjects and lung cancer patients.
Lung Neoplasms
Inhibiting DX2-p14/ARF Interaction Exerts Antitumor Effects in Lung Cancer and Delays Tumor Progression.
Lung Neoplasms
Investigation of myositis and scleroderma specific autoantibodies in patients with lung cancer.
Lung Neoplasms
Label-free molecular probe based on G-quadruplex and strand displacement for sensitive and selective detection and naked eye discrimination of exon 2 deletion of AIMP2.
Lung Neoplasms
Overcoming Radiation Resistance by Iron-Platinum Metal Alloy Nanoparticles in Human Copper Transport 1-Overexpressing Cancer Cells via Mitochondrial Disturbance.
Lupus Erythematosus, Discoid
Treatment of subacute and chronic discoid lupus erythematosus with intensive calcium pantothenate therapy.
Lupus Erythematosus, Systemic
A sensitive immunoenzymometric assay for 2',5'-oligoadenylate. Detection of elevated 2',5'-oligoadenylate synthetase in human peripheral mononuclear cells.
Lupus Erythematosus, Systemic
Could 2'5'-oligoadenylate synthetase isoforms be biomarkers to differentiate between disease flare and infection in lupus patients? A pilot study.
Lupus Erythematosus, Systemic
Interferon-induced 2'-5' adenylate synthetase in vivo and interferon production in vitro by lymphocytes from systemic lupus erythematosus patients with and without circulating interferon.
Lupus Erythematosus, Systemic
Oligo-2',5'-adenylate synthetase activity in peripheral blood mononuclear leukocytes in various diseases.
Lupus Erythematosus, Systemic
[The correlation of myxovirus resistance 1 and 2'5'-ollgoadenylate synthetase 1 with clinical features of systemic lupus erythematosus]
Lupus Nephritis
Abnormal prostanoid metabolism in lupus nephritis and the effects of a thromboxane A2 synthetase inhibitor, DP-1904.
Lupus Nephritis
Improvement of renal function with a selective thromboxane A2 synthetase inhibitor, DP-1904, in lupus nephritis.
Lupus Nephritis
Production of thromboxane A2 and prostaglandin i2 affected by interaction of heat aggregated IgG, endothelial cells, and platelets in lupus nephritis.
Lupus Nephritis
[Oxidation status and ?-glutamylcysteine synthetase expression in the kidney of MRL/lpr lupus mice].
Lymphatic Metastasis
[Relationship between the anti-metastatic effect of UFT and in vitro chemosensitivity to 5-FU in metastatic tumors from orthotopic implanted colon cancer in nude rats]
Lymphocytic Choriomeningitis
Altered tissue distribution of viral replication and T cell spreading is pivotal in the protection against fatal lymphocytic choriomeningitis in mice after neutralization of IFN-alpha/beta.
Lymphohistiocytosis, Hemophagocytic
A case of anti-aminoacyl tRNA synthetase antibody syndrome complicated by hemophagocytic syndrome.
Lymphohistiocytosis, Hemophagocytic
[A case of atrial septal defect complicated by persistent left superior vena cava in whom hemophagocytic syndrome appeared after operation]
Lymphoma
Clinical significance of polyglutamylation in primary central nervous system lymphoma.
Lymphoma
L-asparaginyl-tRNA synthetase and L-asparagine synthetase activities of L-asparaginase-sensitive and -resistant forms of the mouse Gardner lymphoma 6C3HED.
Lymphoma
Participation of poly(ADP-ribosyl)ation in the depression of RNA synthesis caused by treatment of mouse lymphoma cells with methylnitrosourea.
Lymphoma
The effect of tumour growth on liver pantothenate, CoA, and fatty acid synthetase activity in the mouse.
Lymphoma, B-Cell
Effects of dietary protein levels on the disease resistance, immune function and physical barrier function in the gill of grass carp (Ctenopharyngodon idella) after challenged with Flavobacterium columnare.
Lymphoma, B-Cell
Optimal dietary protein level improved growth, disease resistance, intestinal immune and physical barrier function of young grass carp (Ctenopharyngodon idella).
Lymphoma, Large B-Cell, Diffuse
Enhancement of interferon-induced 2-5 oligoadenylate synthetase activity by retinoic acid in human histiocytic lymphoma U937 cells and WISH cells.
Lymphoma, Non-Hodgkin
Alterations in hepatic heme and cytochrome P-450 metabolism in Murphy-Sturm lymphosarcoma-bearing rats. Implications for drug metabolism.
Malabsorption Syndromes
[Activity of glucosamine synthetase in the small intestine mucosa in children with malabsorption syndromes]
Malaria
Activation of Anopheles stephensi Pantothenate Kinase and Coenzyme A Biosynthesis Reduces Infection with Diverse Plasmodium Species in the Mosquito Host.
Malaria
Characterisation of the dihydrofolate reductase-thymidylate synthetase gene from human malaria parasites highly resistant to pyrimethamine.
Malaria
Developing Pantetheinase-Resistant Pantothenamide Antibacterials: Structural Modification Impacts on PanK Interaction and Mode of Action.
Malaria
Drug targeting of one or more aminoacyl-tRNA synthetase in the malaria parasite Plasmodium falciparum.
Malaria
Exploiting the coenzyme A biosynthesis pathway for the identification of new antimalarial agents: the case for pantothenamides.
Malaria
Feedback inhibition of pantothenate kinase regulates pantothenol uptake by the malaria parasite.
Malaria
Genetic Characterization of Coenzyme A Biosynthesis Reveals Essential Distinctive Functions during Malaria Parasite Development in Blood and Mosquito.
Malaria
Genetic Characterization of Plasmodium Putative Pantothenate Kinase Genes Reveals Their Essential Role in Malaria Parasite Transmission to the Mosquito.
Malaria
Identification and functional analysis of the primary pantothenate transporter, PfPAT, of the human malaria parasite Plasmodium falciparum.
Malaria
Insights into the preclinical treatment of blood-stage malaria by the antibiotic borrelidin.
Malaria
Pantothenamides are potent, on-target inhibitors of Plasmodium falciparum growth when serum pantetheinase is inactivated.
Malaria
Piperaquine and Lumefantrine resistance in Plasmodium berghei ANKA associated with increased expression of Ca2+/H+ antiporter and glutathione associated enzymes.
Malaria
Plasmodium yoelii vitamin B5 pantothenate transporter candidate is essential for parasite transmission to the mosquito.
Malaria
Structure-activity analysis of CJ-15,801 analogues that interact with Plasmodium falciparum pantothenate kinase and inhibit parasite proliferation.
Malaria
The cytoplasmic prolyl-tRNA synthetase of the malaria parasite is a dual-stage target of febrifugine and its analogs.
Malaria
The dihydrofolate reductase-thymidylate synthetase gene in the drug resistance of malaria parasites.
Malaria
The growing pipeline of natural aminoacyl-tRNA synthetase inhibitors for malaria treatment.
Malaria, Avian
The human malaria parasite Plasmodium falciparum is not dependent on host coenzyme A biosynthesis.
Malnutrition
Effect of malnutrition on susceptibility of rats to Trypanosoma cruzi. III. Pantothenate deficiency.
Maple Syrup Urine Disease
Continuous venovenous haemofiltration in the acute treatment of inborn errors of metabolism.
Mastocytoma
Influence of nitric oxide on the intracellular reduced glutathione pool: different cellular capacities and strategies to encounter nitric oxide-mediated stress.
Measles
2',5'-Oligoadenylate synthetase and interferon in peripheral blood after rubella, measles, or mumps live virus vaccine.
Measles
Oligo-2',5'-adenylate synthetase activity in K562 cell lines persistently infected with measles or mumps virus.
Melanoma
Effects of alpha- and beta-arbutin on activity of tyrosinases from mushroom and mouse melanoma.
Melanoma
Evaluation of usefulness in surfactant protein D as a predictor of mortality in myositis-associated interstitial lung disease.
Melanoma
Evaluation on serum 2'-5'oligoadenylate synthetase (2'-5'oligoAS) and beta 2 microglobulin (B2M) in patients with nodal metastases from cutaneous malignant melanoma treated with rIFN-alpha 2A.
Melanoma
Growth regulation of melanoma cells by interferon and (2'-5')oligoadenylate synthetase.
Melanoma
In vivo induction of the interferon-stimulated protein 2'5'-oligoadenylate synthetase in tumor and peripheral blood cells during IFN-alpha treatment of metastatic melanoma.
Melanoma
Induction of arginosuccinate synthetase (ASS) expression affects the antiproliferative activity of arginine deiminase (ADI) in melanoma cells.
Melanoma
Recombinant human IFN-gamma, but not IFN-alpha or IFN-beta, enhances MHC- and non-MHC-encoded glycoproteins by a protein synthesis-dependent mechanism.
Melanoma
[Serum interferon level and (2'-5')-oligo(A) synthetase activity in malignant melanoma]
Melanoma
[Serum interferon level and (2'-5')-oligo(A) synthetase activity in pityriasis rosea, basalioma, melanoma and molluscum contagiosum]
Melanoma, Experimental
Effects of D-threo-PDMP, an inhibitor of glucosylceramide synthetase, on expression of cell surface glycolipid antigen and binding to adhesive proteins by B16 melanoma cells.
Melanoma, Experimental
Resistance to the antiproliferative activity of IFN-alpha: further characterization and demonstration of antagonistic effects of IFN-gamma.
Melioidosis
A plant pathogen virulence factor inhibits the eukaryotic proteasome by a novel mechanism.
Meningitis
3-Aminobenzamide, a poly (ADP-ribose) synthetase inhibitor, attenuates the acute inflammatory responses and brain injury in experimental Escherichia coli meningitis in the newborn piglet.
Meningitis
Site-specific immobilization of enzymes on magnetic nanoparticles and their use in organic synthesis.
Meningitis, Bacterial
3-Aminobenzamide, a poly (ADP-ribose) synthetase inhibitor, attenuates the acute inflammatory responses and brain injury in experimental Escherichia coli meningitis in the newborn piglet.
Meningitis, Escherichia coli
3-Aminobenzamide, a poly (ADP-ribose) synthetase inhibitor, attenuates the acute inflammatory responses and brain injury in experimental Escherichia coli meningitis in the newborn piglet.
Meningitis, Viral
[Early diagnosis of central nervous system (CNS) viral infections in the neonatal period and early infancy]
Menorrhagia
Clinical experience with Norplant subdermal implant system as long-term contraception during adolescence.
Mesenteric Ischemia
Poly (ADP-ribose) synthetase mediates intestinal mucosal barrier dysfunction after mesenteric ischemia.
Mesothelioma
Folylpoly-Glutamate Synthetase Expression Is Associated with Tumor Response and Outcome from Pemetrexed-Based Chemotherapy in Malignant Pleural Mesothelioma.
Mesothelioma, Malignant
Folylpoly-Glutamate Synthetase Expression Is Associated with Tumor Response and Outcome from Pemetrexed-Based Chemotherapy in Malignant Pleural Mesothelioma.
Metabolic Diseases
[A new inherited metabolic disease: delta1-pyrroline 5-carboxylate synthetase deficiency]
Metabolic Diseases
[Three congenital metabolic diseases in the Faeroe Islands. Incidence, clinical and molecular genetic characteristics of Faeroese children with glycogen storage disease type IIIA, carnitine transporter deficiency and holocarboxylase synthetase deficiency]
Metabolic Syndrome
Intestinal Population in Host with Metabolic Syndrome during Administration of Chitosan and Its Derivatives.
methylcrotonoyl-coa carboxylase deficiency
[Screening for newborn organic aciduria in Zhejiang province:prevalence, outcome and follow-up].
Microcephaly
Congenital Visual Impairment and Progressive Microcephaly Due to Lysyl-Transfer Ribonucleic Acid (RNA) Synthetase (KARS) Mutations: The Expanding Phenotype of Aminoacyl-Transfer RNA Synthetase Mutations in Human Disease.
Microcephaly
Expansion of the QARS deficiency phenotype with report of a family with isolated supratentorial brain abnormalities.
Microphthalmos
Cloning and characterization of a putative human holocytochrome c-type synthetase gene (HCCS) isolated from the critical region for microphthalmia with linear skin defects (MLS).
Microphthalmos
Genomic structure of a human holocytochrome c-type synthetase gene in Xp22.3 and mutation analysis in patients with Rett syndrome.
Microphthalmos
Loss of holocytochrome c-type synthetase causes the male lethality of X-linked dominant microphthalmia with linear skin defects (MLS) syndrome.
Mitochondrial Diseases
A novel compound heterozygous mutation in VARS2 in a newborn with mitochondrial cardiomyopathy: a case report of a Chinese family.
Mitochondrial Diseases
A patient with juvenile-onset refractory status epilepticus caused by two novel compound heterozygous mutations in FARS2 gene.
Mitochondrial Diseases
Metabolic profiles of exercise in patients with McArdle disease or mitochondrial myopathy.
Mitochondrial Diseases
Mitochondrial Encephalopathy: First Portuguese Report of a VARS2 Causative Variant.
Mitochondrial Diseases
Mitochondrial phenylalanyl-tRNA synthetase mutations underlie fatal infantile Alpers encephalopathy.
Molluscum Contagiosum
[Serum interferon level and (2'-5')-oligo(A) synthetase activity in pityriasis rosea, basalioma, melanoma and molluscum contagiosum]
Motor Neuron Disease
Glycyl tRNA synthetase mutations in Charcot-Marie-Tooth disease type 2D and distal spinal muscular atrophy type V.
Mouth Neoplasms
Extracellular 2'5'-oligoadenylate synthetase 2 mediates T-cell receptor CD3-? chain down-regulation via caspase-3 activation in oral cancer.
Movement Disorders
Deep brain stimulation for pantothenate kinase-associated neurodegeneration: A meta-analysis.
Movement Disorders
Deep brain stimulation improves quality of life in pantothenate kinase-associated neurodegeneration.
Movement Disorders
Deprivation of pantothenic acid elicits a movement disorder and azoospermia in a mouse model of pantothenate kinase-associated neurodegeneration.
Movement Disorders
Mitochondrial iron and energetic dysfunction distinguish fibroblasts and induced neurons from pantothenate kinase-associated neurodegeneration patients.
Movement Disorders
Novel histopathologic findings in molecularly-confirmed pantothenate kinase-associated neurodegeneration.
Movement Disorders
Pallidal neuronal apolipoprotein E in pantothenate kinase-associated neurodegeneration recapitulates ischemic injury to the globus pallidus.
Movement Disorders
Sequence Variations in Mitochondrial Ferritin: Distribution in Healthy Controls and Different Types of Patients.
Movement Disorders
The FOsmetpantotenate Replacement Therapy (FORT) randomized, double-blind, Placebo-controlled pivotal trial: Study design and development methodology of a novel primary efficacy outcome in patients with pantothenate kinase-associated neurodegeneration.
Multiple Myeloma
2',5'-Oligoadenylate synthetase levels in patients with multiple myeloma receiving maintenance therapy with interferon alpha 2b do not correlate with clinical response.
Multiple Sclerosis
Interferon induction, 2'-5' oligo A synthetase and lymphocyte subpopulations in out-patients with multiple sclerosis in a longitudinal study.
Multiple System Atrophy
Chasing shadows: What determines DTI metrics in gray matter regions? An in vitro and in vivo study.
Mumps
2',5'-Oligoadenylate synthetase and interferon in peripheral blood after rubella, measles, or mumps live virus vaccine.
Mumps
Antiviral responses of human Leydig cells to mumps virus infection or poly I:C stimulation.
Mumps
Investigation of IFN type-I receptor and IFN regulatory factor expression relating to induction of 2', 5'-oligoadenylate synthetase in cells persistently infected with the mumps virus.
Mumps
Oligo-2',5'-adenylate synthetase activity in K562 cell lines persistently infected with measles or mumps virus.
Mumps
Suppression of interferon-induced oligo-2',5'-adenylate synthetase induction in persistent infection.
Muscle Weakness
Drop Head Syndrome as a Rare Complication in Mixed Connective Tissue Disease.
Muscular Diseases
Recessive Mutation in a Nuclear-Encoded Mitochondrial tRNA Synthetase Associated With Infantile Cataract, Congenital Neurotrophic Keratitis, and Orbital Myopathy.
Muscular Diseases
[Effect of repeated administration of glucocorticoid on the glycogen level of mouse muscle (author's transl)]
Myalgia
A Rare Combination of Dermatomyositis, Interstitial Pneumonia, and Lung Cancer in a Patient Treated with Immunosuppressive Therapy and Chemotherapy.
Myalgia
Identification of viral infections in pregnancy by assay of (2'-5')-oligo-isoadenylate synthetase.
Myelitis
Treatment with green tea extract attenuates secondary inflammatory response in an experimental model of spinal cord trauma.
Myelodysplastic Syndromes
Sequence Variations in Mitochondrial Ferritin: Distribution in Healthy Controls and Different Types of Patients.
Myocardial Infarction
Different angiogenesis effect of mini-TyrRS/mini-TrpRS by systemic administration of modified siRNAs in rats with acute myocardial infarction.
Myocardial Infarction
Effect of Mini-Tyrosyl-tRNA Synthetase/Mini-Tryptophanyl-tRNA Synthetase on Angiogenesis in Rhesus Monkeys after Acute Myocardial Infarction.
Myocardial Infarction
Effect of mini-tyrosyl-tRNA synthetase/mini-tryptophanyl-tRNA synthetase on ischemic angiogenesis in rats: proliferation and migration of endothelial cells.
Myocardial Infarction
High expression of long chain acyl-coenzyme A synthetase 1 in peripheral blood may be a molecular marker for assessing the risk of acute myocardial infarction.
Myocardial Infarction
Natural aminoacyl tRNA synthetase fragment enhances cardiac function after myocardial infarction.
Myocardial Infarction
Prevention of myocardial reperfusion injury by poly(ADP-ribose) synthetase inhibitor, 3-aminobenzamide, in cardioplegic solution: in vitro study of isolated rat heart model.
Myocardial Infarction
Reduced myocardial neutrophil accumulation and infarct size following thromboxane synthetase inhibitor or receptor antagonist.
Myocardial Infarction
Reduction in myocardial neutrophil accumulation and infarct size following administration of thromboxane inhibitor U-63,557A.
Myocardial Infarction
[Amino acyl tRNA synthetase complexes in rabbit liver in experimental myocardial infarction]
Myocardial Infarction
[Distribution of aminoacyl-t-RNA-synthetase activity in rabbit liver cells during disruption of protein biosynthesis in experimental myocardia infarct]
Myocardial Ischemia
Protection against myocardial ischemia and reperfusion injury by 3-aminobenzamide, an inhibitor of poly (ADP-ribose) synthetase.
Myocardial Ischemia
Subcellular distribution and properties of rabbit liver aminoacyl-tRNA synthetases under myocardial ischemia.
Myocardial Ischemia
[Effect of calcium pantothenate on vitamin B6 and C correlation in patients with hypertension and ischemic heart disease]
Myocardial Reperfusion Injury
Prevention of myocardial reperfusion injury by poly(ADP-ribose) synthetase inhibitor, 3-aminobenzamide, in cardioplegic solution: in vitro study of isolated rat heart model.
Myocardial Reperfusion Injury
Reduction of myocardial reperfusion injury by an inhibitor of poly (ADP-ribose) synthetase in the pig.
Myoclonus
Novel Compound Heterozygous Mutations Expand the Recognized Phenotypes of FARS2-Linked Disease.
Myositis
A motif in human histidyl-tRNA synthetase which is shared among several aminoacyl-tRNA synthetases is a coiled-coil that is essential for enzymatic activity and contains the major autoantigenic epitope.
Myositis
A woman with anti-histidyl-aminoacyl-tRNA synthetase (Jo-1 antibodies), myositis, hyperglycemia, interstitial lung disease, and morbilliform rashes.
Myositis
Acute Onset Anti-Synthetase Syndrome With Pericardial Effusion and Non-Specific Interstitial Pneumonia.
Myositis
Anti-aminoacyl tRNA synthetase immune responses: insights into the pathogenesis of the idiopathic inflammatory myopathies.
Myositis
Anti-aminoacyl-tRNA synthetase antibodies in clinical course prediction of interstitial lung disease complicated with idiopathic inflammatory myopathies.
Myositis
Anti-PL-7 (anti-threonyl-tRNA synthetase) antisynthetase syndrome: clinical manifestations in a series of patients from a European multicenter study (EUMYONET) and review of the literature.
Myositis
Anti-Ro52 antibodies frequently co-occur with anti-Jo-1 antibodies in sera from patients with idiopathic inflammatory myopathy.
Myositis
Anti-Ro52 autoantibodies are associated with interstitial lung disease and more severe disease in patients with juvenile myositis.
Myositis
Clinical and immunogenetic features of patients with autoantibodies to asparaginyl-transfer RNA synthetase.
Myositis
Clinical characteristics of interstitial lung diseases positive to different anti-synthetase antibodies.
Myositis
Clinical manifestations in patients with antibody to PL-12 antigen (alanyl-tRNA synthetase).
Myositis
Clinical, radiological, and pathological features of anti-asparaginyl tRNA synthetase antibody-related interstitial lung disease.
Myositis
Correlation of Antisynthetase Antibody Levels with Disease Course in a Patient with Interstitial Lung Disease and Elevated Muscle Enzymes.
Myositis
Dermatomyositis: an association of gingival telangiectases and anti Jo-1 antibody in the adult.
Myositis
Do associated auto-antibodies influence the outcome of myasthenia gravis after thymectomy?
Myositis
Early predominant inflammatory myopathy in anti-glycyl-tRNA synthetase (EJ) antibody positive antisynthetase syndrome.
Myositis
Efficacy of Rituximab in Refractory Inflammatory Myopathies Associated with Anti- Synthetase Auto-Antibodies: An Open-Label, Phase II Trial.
Myositis
Epidemiology of Idiopathic Inflammatory Myopathies in Africa: A Contemporary Systematic Review.
Myositis
Establishment of an ELISA to detect anti-glycyl-tRNA synthetase antibody (anti-EJ), a serological marker of dermatomyositis/polymyositis and interstitial lung disease.
Myositis
Genome-wide association study identifies HLA 8.1 ancestral haplotype alleles as major genetic risk factors for myositis phenotypes.
Myositis
Immune recognition of lysyl-tRNA synthetase and isoleucyl-tRNA synthetase by anti-OJ antibody-positive sera.
Myositis
Inflammatory myopathy, bronchiolitis obliterans/organizing pneumonia, and anti-Jo-1 antibodies--an interesting association.
Myositis
Jo-1 autoantigen-specific B cells are skewed towards distinct functional B cell subsets in anti-synthetase syndrome patients.
Myositis
Oxygen-Dependent Patient with Antisynthetase Syndrome Associated Interstitial Lung Disease Responds Promptly to Rituximab with Rapid Pulmonary Function Improvement.
Myositis
Patients with anti-Jo1 antibodies display a characteristic IgG Fc-glycan profile which is further enhanced in anti-Jo1 autoantibodies.
Myositis
Prevalence of antibodies to Ro-52 in a serologically defined population of patients with systemic sclerosis.
Myositis
Pulmonary Pathologic Manifestations of Anti-Alanyl-tRNA Synthetase (Anti-PL-12)-Related Inflammatory Myopathy.
Myositis
Pulmonary pathologic manifestations of anti-glycyl-tRNA synthetase (anti-EJ)-related inflammatory myopathy.
Myositis
The pulmonary histopathologic manifestations of the anti-Jo-1 tRNA synthetase syndrome.
Myositis
Toll like receptor-7/8 activation exacerbates murine experimental autoimmune myositis.
Myositis
[Anti-Jo-1 antibody and anti-aminoacyl-tRNA synthetase antibody as a marker autoantibody for myositis]
Myositis
[Autoantibodies specifically detected in patients with polymyositis/dermatomyositis]
Myositis
[Clinical and pathological findings of patients with interstitial lung disease associated with antisynthetase]
Myositis
[How can we diagnose and better understand inflammatory myopathies? The usefulness of auto-antibodies].
Myositis
[Two cases of polymyositis associated with interstitial pneumonia with anti-OJ (isoleucyl tRNA synthetase) antibodies]
Neoplasm Metastasis
Evading immune surveillance via tyrosine phosphorylation of nuclear PCNA.
Neoplasm Metastasis
Evaluation on serum 2'-5'oligoadenylate synthetase (2'-5'oligoAS) and beta 2 microglobulin (B2M) in patients with nodal metastases from cutaneous malignant melanoma treated with rIFN-alpha 2A.
Neoplasm Metastasis
Inhibition of tumor cell metastasis by modulation of the vascular prostacyclin/thromboxane A2 system.
Neoplasm Metastasis
Prostaglandin and thromboxane synthesis by M5076 ovarian reticulosarcoma during growth: effects of a thromboxane synthetase inhibitor.
Neoplasm Metastasis
Resistance of cyclooxygenase-2 expressing pancreatic ductal adenocarcinoma cells against ?? T cell cytotoxicity.
Neoplasm Metastasis
[Relationship between the anti-metastatic effect of UFT and in vitro chemosensitivity to 5-FU in metastatic tumors from orthotopic implanted colon cancer in nude rats]
Neoplasms
2',5'-oligoadenylate synthetase activity in human mammary tumors and its potential correlation with tumor growth or hormonal responsiveness.
Neoplasms
2-Aminophenylpyrimidines as Novel Inhibitors of Aminoacyl-tRNA Synthetase Interacting Multifunctional Protein 2 (AIMP2)-DX2 for Lung Cancer Treatment.
Neoplasms
5-Substituted 2'-deoxyuridines: correlation between inhibition of tumor cell growth and inhibition of thymidine kinase and thymidylate synthetase.
Neoplasms
A retrospective cohort study in Chinese patients with adult polymyositis and dermatomyositis: risk of comorbidities and subclassification using machine learning.
Neoplasms
A translation independent function of PheRS/FARS activates growth and proliferation.
Neoplasms
Aberration of poly(adenosine diphosphate-ribose) metabolism in human colon adenomatous polyps and cancers.
Neoplasms
Action of interferon-alpha on hairy cell leukemia: expression of specific receptors and (2'-5')oligo (A) synthetase in tumor cells from sensitive and resistant patients.
Neoplasms
Activation of histamine H4 receptor suppresses the proliferation and invasion of esophageal squamous cell carcinoma via both metabolism and non-metabolism signaling pathways.
Neoplasms
Adoptive immunotherapy of human cancer: the cytokine cascade and monocyte activation following high-dose interleukin 2 bolus treatment.
Neoplasms
ADP-ribosylation of chromosomal proteins and mouse mammary tumor virus gene expression. Glucocorticoids rapidly decrease endogenous ADP-ribosylation of nonhistone high mobility group 14 and 17 proteins.
Neoplasms
AIMP2-DX2 Promotes the Proliferation, Migration, and Invasion of Nasopharyngeal Carcinoma Cells.
Neoplasms
Alterations of hepatic delta-aminolevulinic acid synthetase, heme oxygenase, microsomal cytochrome content and drug metabolism in rats bearing ascitic tumors AH 13, AH 66 and AH 414 and a 3-methylcholanthrene induced tumor.
Neoplasms
Ameliorative role of curcumin on copper oxide nanoparticles-mediated renal toxicity in rats: An investigation of molecular mechanisms.
Neoplasms
Antioxidant enzymes in oligodendroglial brain tumors: association with proliferation, apoptotic activity and survival.
Neoplasms
Antitumor agents XXVII: Effects of helenalin on anaerobic and aerobic metabolism of Ehrlich ascites cells.
Neoplasms
Antitumoral action of interferon and poly(A)poly(U) on HeLa xenografts in the nude mouse.
Neoplasms
Antiviral activity of tumour necrosis factor. Synergism with interferons and induction of oligo-2',5'-adenylate synthetase.
Neoplasms
Biochemical determinants of responsiveness to 5-fluorouracil and its derivatives in xenografts of human colorectal adenocarcinomas in mice.
Neoplasms
Biomarkers for cetuximab-based neoadjuvant radiochemotherapy in locally advanced rectal cancer.
Neoplasms
Cancer Association Study of Aminoacyl-tRNA Synthetase Signaling Network in Glioblastoma.
Neoplasms
Cancer-associated splicing variant of tumor suppressor AIMP2/p38: pathological implication in tumorigenesis.
Neoplasms
Cancer-Specific Production of N-Acetylaspartate via NAT8L Overexpression in Non-Small Cell Lung Cancer and Its Potential as a Circulating Biomarker.
Neoplasms
Cholesterol Synthetase DHCR24 Induced by Insulin Aggravates Cancer Invasion and Progesterone Resistance in Endometrial Carcinoma.
Neoplasms
Clinical value of the determination of an interferon-induced enzyme activity: studies of the 2'5' oligoadenylate synthetase activity in peripheral blood lymphocytes of patients.
Neoplasms
Collagen metabolism as a regulator of proline dehydrogenase/proline oxidase-dependent apoptosis/autophagy.
Neoplasms
Control of -aminolevulinic acid synthetase and tyrosine aminotransferase in tumors and livers of tumor-bearing rats.
Neoplasms
Control of leucine-dependent mTORC1 pathway through chemical intervention of leucyl-tRNA synthetase and RagD interaction.
Neoplasms
Control of pyrimidine biosynthesis in mammalian tissues. II. Glutamine-utilizing carbamoyl phosphate synthetase of various experimental tumors: distribution, purification and characterization.
Neoplasms
Depression in gene expression for poly(ADP-ribose) synthetase during the interferon-gamma-induced activation process of murine macrophage tumor cells.
Neoplasms
Determination of three-dimensional structure and residues of the novel tumor suppressor AIMP3/p18 required for the interaction with ATM.
Neoplasms
Development and therapeutic options for the treatment of raloxifene-stimulated breast cancer in athymic mice.
Neoplasms
Development of a chemoresistant orthotopic human nonsmall cell lung carcinoma model in nude mice: analyses of tumor heterogenity in relation to the immunohistochemical levels of expression of cyclooxygenase-2, ornithine decarboxylase, lung-related resistance protein, prostaglandin E synthetase, and glutathione-S-transferase-alpha (GST)-alpha, GST-mu, and GST-pi.
Neoplasms
Dichlorodiphenyldichloroethylene exposure reduces r-GCS via suppressed Nrf2 in HepG2 cells.
Neoplasms
Dietary alpha-linolenic acid reduces COX-2 expression and induces apoptosis of hepatoma cells.
Neoplasms
Differences in total mitochondrial proteins and proteins synthesized by mitochondria from rat liver and Morris hepatomas 9618A, 5123C, and 5123tc.
Neoplasms
Direct action of interferon and inducers of interferon on tumor cells in athymic nude mice.
Neoplasms
Discovery of novel tRNA-amino acid dual-site inhibitors against threonyl-tRNA synthetase by fragment-based target hopping.
Neoplasms
DNA fragmentation and NAD depletion. Their relation to the turnover of endogenous mono(ADP-ribosyl) and poly(ADP-ribosyl) proteins.
Neoplasms
DNA strand breaks and poly(ADP-ribose) synthetase activation in pancreatic islets--a new aspect to development of insulin-dependent diabetes and pancreatic B-cell tumors.
Neoplasms
Do NSAIDs exert their colon cancer chemoprevention activities through the inhibition of mucosal prostaglandin synthetase?
Neoplasms
Downregulation of lamin A by tumor suppressor AIMP3/p18 leads to a progeroid phenotype in mice.
Neoplasms
Effect of alkylating agents on glycogen synthetase activity of ascites tumor cells.
Neoplasms
Effect of interleukin-2 on some micronutrients during adoptive immunotherapy for various cancers.
Neoplasms
Effect of select medium supplements on in vitro development of Cryptosporidium andersoni in HCT-8 cells.
Neoplasms
Effects of intravenous infusion of trans-10, cis-12 18:2 on mammary lipid metabolism in lactating dairy cows.
Neoplasms
Effects of thromboxane A2 inhibition on osteogenic sarcoma cell-induced platelet aggregation.
Neoplasms
Enhancement of glutathione and g-glutamylcysteine synthetase, the rate limiting enzyme of glutathione synthesis, by chemoprotective plant-derived food and beverage components in the human hepatoma cell line HepG2.
Neoplasms
Enhancement of the innate and cellular immune response in patients with genital warts treated with topical imiquimod cream 5%.
Neoplasms
Estrogen represses Hepatocellular Carcinoma (HCC) growth via inhibiting alternative activation of tumor-associated macrophages (TAMs).
Neoplasms
Evaluation of endogenous acidic metabolic products associated with carbohydrate metabolism in tumor cells.
Neoplasms
Expression of Lipid Metabolism-Related Proteins Differs between Invasive Lobular Carcinoma and Invasive Ductal Carcinoma.
Neoplasms
Factors that influence the therapeutic activity of 5-fluorouracil [6RS]leucovorin combinations in colon adenocarcinoma xenografts.
Neoplasms
Fatty acid synthetase and its mRNA are induced by progestins in breast cancer cells.
Neoplasms
Folylpoly-?-glutamate synthetase: A key determinant of folate homeostasis and antifolate resistance in cancer.
Neoplasms
Folylpoly-Glutamate Synthetase Expression Is Associated with Tumor Response and Outcome from Pemetrexed-Based Chemotherapy in Malignant Pleural Mesothelioma.
Neoplasms
Gene expression signature of primary imatinib-resistant chronic myeloid leukemia patients.
Neoplasms
Gene therapy for head and neck cancer using vaccinia virus expressing IL-2 in a murine model, with evidence of immune suppression.
Neoplasms
Genome-wide CRISPR/Cas9 knockout screening uncovers a novel inflammatory pathway critical for resistance to arginine-deprivation therapy.
Neoplasms
Glucocorticoid agonists as well as antagonists are effective inducers of mouse mammary tumor virus RNA in mouse mammary tumor cells treated with inhibitors of ADP-ribosylation.
Neoplasms
Glucocorticoid receptor knockdown decreases the antioxidant protection of B16 melanoma cells: an endocrine system-related mechanism that compromises metastatic cell resistance to vascular endothelium-induced tumor cytotoxicity.
Neoplasms
Glutathione S-transferase-P1 expression correlates with increased antioxidant capacity in transitional cell carcinoma of the urinary bladder.
Neoplasms
Green Tea Polyphenols Ameliorate Pancreatic Injury in Cerulein-Induced Murine Acute Pancreatitis.
Neoplasms
Guanosine-5'-phosphate synthetase and guanosine-5'-phosphate kinase in rat hepatomas and kidney tumors.
Neoplasms
Heme regulation in mouse mammary carcinoma and liver of tumor bearing mice--I. Effect of allyl-isopropylacetamide and veronal on delta-aminolevulinate synthetase, cytochrome P-450 and cytochrome oxidase.
Neoplasms
Heterogeneous nuclear RNA from hairy cell leukemia patients activates 2',5'-oligoadenylate synthetase.
Neoplasms
High throughput proteomic and metabolic profiling identified target correction of metabolic abnormalities as a novel therapeutic approach in head and neck paraganglioma.
Neoplasms
Human lung cancer nodules in organotypic culture: no evidence of correlation between the antiproliferative effects of interferons and the induction of 2',5'-oligoadenylate synthetase.
Neoplasms
Human lymphoblastoid interferon. In vitro and in vivo studies in hepatocellular carcinoma.
Neoplasms
Immunological Microenvironment Predicts the Survival of the Patients with Hepatocellular Carcinoma Treated with Anti-PD-1 Antibody.
Neoplasms
In vitro inhibition of cytidine triphosphate synthetase activity by cyclopentenyl cytosine in paediatric acute lymphocytic leukaemia.
Neoplasms
In vivo and in vitro induction of (2'-5') oligoadenylate synthetase by human interferons in leukocytes from healthy donors and patients with renal cancer and hairy cell leukemia.
Neoplasms
In vivo induction of the interferon-stimulated protein 2'5'-oligoadenylate synthetase in tumor and peripheral blood cells during IFN-alpha treatment of metastatic melanoma.
Neoplasms
Increased carbamoyl-phosphate synthetase II concentration in rat hepatomas: immunological evidence.
Neoplasms
Induction of 2',5' oligo(A) synthetase in tumor-bearing mice with encephalomyocarditis (EMC) virus or poly(I)poly(C).
Neoplasms
Induction of 2',5'-oligoadenylate synthetase activity in peripheral blood mononuclear cells by gamma interferon.
Neoplasms
Induction of 2',5'-oligoadenylate synthetase in freshly separated malignant cells from solid tumors. Variability in the susceptibility of interferon.
Neoplasms
Induction of 2',5'oligo (A) synthetase in animals bearing Ehrlich ascites tumor cells.
Neoplasms
Induction of Apoptosis and Reduction of Endogenous Glutathione Level by the Ethyl-Acetate Soluble Fraction of the Methanol Extract of the Roots of Potentilla fulgens in Cancer Cells.
Neoplasms
Induction of rat pancreatic B-cell tumors by the combined administration of streptozotocin or alloxan and poly(adenosine diphosphate ribose) synthetase inhibitors.
Neoplasms
Inhibition of human HT29 colon carcinoma growth in vitro and in vivo by swainsonine and human interferon-alpha 2.
Neoplasms
Inhibition of potentially lethal radiation damage repair in normal and neoplastic human cells by 3-aminobenzamide: an inhibitor of poly(ADP-ribosylation).
Neoplasms
Inhibition of the phosphoribosyl-formylglycineamidine synthetase of Ehrlich ascites tumor cells by glutamine analogues.
Neoplasms
Interferon gamma regulates a unique set of proteins in fresh human bladder transitional cell carcinomas.
Neoplasms
Interferon, double-stranded RNA, and RNA degradation. Isolation of homogeneous pppA(2'p5'A)n-1 synthetase from Ehrlich ascites tumor cells.
Neoplasms
Interferons, double-stranded RNA, and RNA degradation. Isolation and characterization of homogeneous human (2'-5')(a)n synthetase.
Neoplasms
L-asparaginyl-tRNA synthetase and L-asparagine synthetase activities of L-asparaginase-sensitive and -resistant forms of the mouse Gardner lymphoma 6C3HED.
Neoplasms
Label-free molecular probe based on G-quadruplex and strand displacement for sensitive and selective detection and naked eye discrimination of exon 2 deletion of AIMP2.
Neoplasms
Levels of acyl-coenzyme A synthetase 5 in urothelial cells and corresponding neoplasias reflect cellular differentiation.
Neoplasms
Lipid metabolism and enzyme activities in hormone-dependent and hormone-independent mammary adenocarcinoma in GR mice.
Neoplasms
Long-term treatment of malignant gliomas with intramuscularly administered polyinosinic-polycytidylic acid stabilized with polylysine and carboxymethylcellulose: an open pilot study.
Neoplasms
Measurement of interferon sensitivity in tumour cells from fine-needle aspirations.
Neoplasms
Methotrexate analogues. 26. Inhibition of dihydrofolate reductase and folylpolyglutamate synthetase activity and in vitro tumor cell growth by methotrexate and aminopterin analogues containing a basic amino acid side chain.
Neoplasms
miR-543 and miR-590-3p regulate human mesenchymal stem cell aging via direct targeting of AIMP3/p18.
Neoplasms
Molecular basis and current strategies of therapeutic arginine depletion for cancer.
Neoplasms
Molecular docking studies of flavonoids for their inhibition pattern against ?-catenin and pharmacophore model generation from experimentally known flavonoids to fabricate more potent inhibitors for Wnt signaling pathway.
Neoplasms
N-terminus of pro-EMAP II regulates its binding with C-terminus, Arginyl-tRNA Synthetase, and Neurofilament light protein.
Neoplasms
Nelumbo nucifera Leaves Prevent NMU-Induced Mammary Tumor through Downregulation of Fatty Acid Synthase, Estrogen Receptor-? and Her2 Expression.
Neoplasms
Nitric oxide enhances PGI(2)production by human pulmonary artery smooth muscle cells.
Neoplasms
Nitric oxide mediates natural polyphenol-induced Bcl-2 down-regulation and activation of cell death in metastatic B16 melanoma.
Neoplasms
Novel mRNA isoforms and mutations of uridine monophosphate synthetase and 5-fluorouracil resistance in colorectal cancer.
Neoplasms
Oncogenic Mutation of AIMP2/p38 Inhibits Its Tumor-Suppressive Interaction with Smurf2.
Neoplasms
Opposite sensitivity to the antiproliferative action of interferon-alpha and granulocyte-macrophage colony-stimulating factor in monoblastic U937 cells.
Neoplasms
Paeonia japonica, Houttuynia cordata, and Aster scaber water extracts induce nitric oxide and cytokine production by lipopolysaccharide-activated macrophages.
Neoplasms
Participation of poly(ADP-ribose) synthetase in the process of norepinephrine-induced inhibition of major histocompatibility complex class II antigen expression in human astrocytoma cells.
Neoplasms
Peroxisomal proliferators inhibit acyl CoA synthetase and stimulate protein kinase C in vivo.
Neoplasms
Phase I/II trial of recombinant gamma-interferon in patients with renal cell carcinoma: immunologic and biologic effects.
Neoplasms
Polyadenylic-polyuridylic acid: biological response-modifying activities in mice. In vivo organ distribution and pharmacokinetics in rabbits.
Neoplasms
Progestin-induced fatty acid synthetase in human mammary tumors: from molecular to clinical studies.
Neoplasms
Proliferation-linked increase in phosphoribosylformylglycinamidine synthetase activity (EC 6.3.5.3).
Neoplasms
Prostaglandin and thromboxane synthesis by M5076 ovarian reticulosarcoma during growth: effects of a thromboxane synthetase inhibitor.
Neoplasms
Purification and properties of phosphoribosyl-formylglycineamidine synthetase of ehrlich ascites tumor cells.
Neoplasms
Rapid detection of exon 2-deleted AIMP2 mutation as a potential biomarker for lung cancer by molecular beacons.
Neoplasms
Regulation of gene expression by insulin and tumor necrosis factor alpha in 3T3-L1 cells. Modulation of the transcription of genes encoding acyl-CoA synthetase and stearoyl-CoA desaturase-1.
Neoplasms
Regulation of purine metabolism. Adenylosuccinate synthetase from Novikoff ascites tumor cells.
Neoplasms
Regulatory properties and behavior of activity of carbamoyl phosphate synthetase II (glutamine-hydrolyzing) in normal and proliferating tissues.
Neoplasms
Resistance of cyclooxygenase-2 expressing pancreatic ductal adenocarcinoma cells against ?? T cell cytotoxicity.
Neoplasms
Response of L-1210 tumor in mice toward treatment with interferon or poly(I) X poly(C).
Neoplasms
Rhodanese and ALA-S in mammary tumor and liver from normal and tumor-bearing mice.
Neoplasms
Selective Labeling and Identification of the Tumor Cell Proteome of Pancreatic Cancer In Vivo.
Neoplasms
Structural characterization of antibiotic self-immunity tRNA synthetase in plant tumour biocontrol agent.
Neoplasms
Studies on resistance against 5-fluorouracil. II. Thymidylate synthetase from drug-resistant tumor lines.
Neoplasms
Studies on the activities of some methyltransferases in the livers and tumor cells from tumor-bearing mice.
Neoplasms
Studies with pure mouse Ehrlich ascites tumor interferons alpha and beta: patterns of induction of (2'-5') (A)n synthetase and of a double-stranded RNA-dependent protein kinase in mouse cells and human cells.
Neoplasms
Suppression of AIMP1 protects cognition in Alzheimer's disease model mice 3xTg-AD.
Neoplasms
Synergistic effect of interferon-gamma and tumor necrosis factor-alpha on antiviral activity and (2'-5') oligo (A) synthetase induction in a myelomonocytic cell line.
Neoplasms
Synthesis and catabolism of PGE2 by a nephroblastoma associated with hypercalcemia without bone metastases.
Neoplasms
Synthesis of (2'-5')(A)n from ATP. Characteristics of the reaction catalyzed by (2'-5')(A)n synthetase purified from mouse Ehrlich ascites tumor cells treated with interferon.
Neoplasms
Targeting the Vulnerability of Glutathione Metabolism in ARID1A-Deficient Cancers.
Neoplasms
The effect of pre-injection of mice with pristane on ascites tumour formation and monoclonal antibody production.
Neoplasms
The effect of tumour growth on liver pantothenate, CoA, and fatty acid synthetase activity in the mouse.
Neoplasms
The influence of arachidonic acid metabolites on cell division in the intestinal epithelium and in colonic tumors.
Neoplasms
The Role of the Glutathione System in Oxidative Modification of Proteins and Dysregulation of Apoptosis in Jurkat Tumor Cells.
Neoplasms
TNF-induced activation of pulmonary microvessel endothelial cells: a role for GSK3beta.
Neoplasms
Tumor endothelial cell tube formation model for determining anti-angiogenic activity of a tRNA synthetase cytokine.
Neoplasms
Tumor hypoglycemia induced in nude mice by a heterotransplantable human ovarian carcinoma line (OCL-1).
Neoplasms
Ursolic acid isolated from the seed of Cornus officinalis ameliorates colitis in mice by inhibiting the binding of lipopolysaccharide to Toll-like receptor 4 on macrophages.
Neoplasms
Vnn1 pantetheinase limits the Warburg effect and sarcoma growth by rescuing mitochondrial activity.
Neoplasms
White button mushroom phytochemicals inhibit aromatase activity and breast cancer cell proliferation.
Neoplasms
[5-fluorouracil and colorectal tumors: use in clinical practice and the "MISURA" project]
Neoplasms
[Cancer-associated alterations of glycoconjugates--special reference to glycosphingolipids]
Neoplasms
[Detection of gene expression alteration of myeloma cells treated with arsenic trioxide]
Neoplasms
[Immunophenotypic classification of 3 cases of hepatocellular adenoma. Differential diagnosis with focal nodular hyperplasia].
Neoplasms
[The effect of different types of recombinant interferon on the induction of 2,5-oligoadenylate synthetase in natural killers and the tumor cells in bladder cancer patients]
Nephritis
Antinephritic effect of OKY-046, a thromboxane A synthetase inhibitor (1). Effects on crescentic-type anti-GBM nephritis in rats.
Nephritis
Antinephritic effect of Y-19018, a thromboxane A synthetase inhibitor, on crescentic-type anti-GBM nephritis in rats.
Nephritis
Henoch-Schönlein purpura nephritis occurring postpartum in a patient with anti-PL-7 anti-synthetase syndrome.
Nephritis
Studies on antinephritic effect of TJ-8014, a new Japanese herbal medicine, and its mechanisms (2): Effect on the release of corticosterone from adrenal glands.
Nephrotic Syndrome
Clinical effects of selective thromboxane A2 synthetase inhibitor in patients with nephrotic syndrome.
Nervous System Autoimmune Disease, Experimental
Toll like receptor-7/8 activation exacerbates murine experimental autoimmune myositis.
Nervous System Diseases
Characterization of sleep in six patients with pantothenate kinase-associated neurodegeneration.
Nervous System Diseases
Clinical rating scale for pantothenate kinase-associated neurodegeneration: A pilot study.
Nervous System Diseases
Current state of knowledge in Chorea-Acanthocytosis as core Neuroacanthocytosis syndrome.
Nervous System Diseases
Deficient activity of alanyl-tRNA synthetase underlies an autosomal recessive syndrome of progressive microcephaly, hypomyelination, and epileptic encephalopathy.
Nervous System Diseases
Sensory Tricks in Pantothenate Kinase-Associated Neurodegeneration: Video-Analysis of 43 Patients.
Neural Tube Defects
MTHFD1 formyltetrahydrofolate synthetase deficiency, a model for the MTHFD1 R653Q variant, leads to congenital heart defects in mice.
Neuralgia
Cellular mechanisms of neuropathic pain, morphine tolerance, and their interactions.
Neuralgia
Koumine enhances spinal cord 3?-hydroxysteroid oxidoreductase expression and activity in a rat model of neuropathic pain.
Neuralgia
The inhibition of nitric oxide-activated poly(ADP-ribose) synthetase attenuates transsynaptic alteration of spinal cord dorsal horn neurons and neuropathic pain in the rat.
Neuroacanthocytosis
Current state of knowledge in Chorea-Acanthocytosis as core Neuroacanthocytosis syndrome.
Neuroacanthocytosis
Mineral deposition on magnetic resonance imaging in chorea-acanthocytosis: a pathogenic link with pantothenate kinase-associated neurodegeneration?
Neuroacanthocytosis
Severe tongue protrusion dystonia: clinical syndromes and possible treatment.
Neuroacanthocytosis
Tongue Protrusion Dystonia in Pantothenate Kinase-Associated Neurodegeneration.
Neuroaxonal Dystrophies
Consensus clinical management guideline for beta-propeller protein-associated neurodegeneration.
Neuroaxonal Dystrophies
Deep brain stimulation in the globus pallidus compensates response inhibition deficits: evidence from pantothenate kinase-associated neurodegeneration.
Neuroaxonal Dystrophies
Excess iron harms the brain: the syndromes of neurodegeneration with brain iron accumulation (NBIA).
Neuroaxonal Dystrophies
Genetics and Pathophysiology of Neurodegeneration with Brain Iron Accumulation (NBIA).
Neuroaxonal Dystrophies
Infantile neuroaxonal dystrophy and pantothenate-kinase-associated neurodegeneration: locus heterogeneity.
Neuroaxonal Dystrophies
Iron Accumulation in Syndromes of Neurodegeneration with Brain Iron Accumulation 1 and 2 - causative or consequential?
Neuroaxonal Dystrophies
Neurodegeneration with brain iron accumulation: Characterization of clinical, radiological, and genetic features of pediatric patients from Southern India.
Neuroaxonal Dystrophies
Pantothenate kinase-associated neurodegeneration (PKAN) and PLA2G6-associated neurodegeneration (PLAN): review of two major neurodegeneration with brain iron accumulation (NBIA) phenotypes.
Neuroaxonal Dystrophies
Pathophysiology and treatment of neurodegeneration with brain iron accumulation in the pediatric population.
Neuroaxonal Dystrophies
Syndromes of neurodegeneration with brain iron accumulation (NBIA): an update on clinical presentations, histological and genetic underpinnings, and treatment considerations.
Neuroaxonal Dystrophies
T2* and FSE MRI distinguishes four subtypes of neurodegeneration with brain iron accumulation.
Neuroaxonal Dystrophies
Treatment of Classic Pantothenate Kinase-Associated Neurodegeneration with Deferiprone and Intrathecal Baclofen.
Neuroblastoma
DNA (cytosine) methyltransferase overexpression is associated with acquired drug resistance of murine neuroblastoma cells.
Neuroblastoma
Experimental chemotherapy of neuroblastoma. II. Increased thymidylate synthetase activity in a 5-fluorodeoxyuridine-resistant variant of mouse neuroblastoma.
Neuroblastoma
Ganglioside GM2/GD2 synthetase mRNA is a marker for detection of infrequent neuroblastoma cells in bone marrow.
Neuroblastoma
Retinoic acid reduces the cytotoxicity of cyclopentenyl cytosine in neuroblastoma cells.
Neuroblastoma
[Evaluation of urinary excretion of free-cortisol in patients with abnormal pituitary-adrenal axes]
Neurodegenerative Diseases
A new in vivo model of pantothenate kinase-associated neurodegeneration reveals a surprising role for transcriptional regulation in pathogenesis.
Neurodegenerative Diseases
A novel gene mutation in PANK2 in a patient with an atypical form of pantothenate kinase-associated neurodegeneration.
Neurodegenerative Diseases
A novel PANK2 gene mutation: clinical and molecular characteristics of patients short communication.
Neurodegenerative Diseases
A Scale to Assess Activities of Daily Living in Pantothenate Kinase-Associated Neurodegeneration.
Neurodegenerative Diseases
A variation in PANK2 gene is causing Pantothenate kinase-associated Neurodegeneration in a family from Jammu and Kashmir - India.
Neurodegenerative Diseases
Botulinum Toxin-A Injection in the Treatment of Spasticity in a Infantile-Onset Neurodegeneration With Brain Iron Accumulation: A Case Report.
Neurodegenerative Diseases
Coenzyme A corrects pathological defects in human neurons of PANK2-associated neurodegeneration.
Neurodegenerative Diseases
Consensus clinical management guideline for beta-propeller protein-associated neurodegeneration.
Neurodegenerative Diseases
Cyclic Phosphopantothenic Acid Prodrugs for Treatment of Pantothenate Kinase-Associated Neurodegeneration.
Neurodegenerative Diseases
Deep brain stimulation as treatment for dystonic storm in pantothenate kinase-associated neurodegeneration syndrome: case report of a patient with homozygous C.628 2 T?>?G mutation of the PANK2 gene.
Neurodegenerative Diseases
Deficiency of pantothenate kinase 2 (Pank2) in mice leads to retinal degeneration and azoospermia.
Neurodegenerative Diseases
Diagnostic and clinical experience of patients with pantothenate kinase-associated neurodegeneration.
Neurodegenerative Diseases
Early-onset neurodegeneration with brain iron accumulation due to PANK2 mutation.
Neurodegenerative Diseases
Etiology and treatment of adrenoleukodystrophy: new insights from Drosophila.
Neurodegenerative Diseases
Identification and targeted management of a neurodegenerative disorder caused by biallelic mutations in SLC5A6.
Neurodegenerative Diseases
Impaired Coenzyme A metabolism affects histone and tubulin acetylation in Drosophila and human cell models of pantothenate kinase associated neurodegeneration.
Neurodegenerative Diseases
Lethal NARS2-Related Disorder Associated With Rapidly Progressive Intractable Epilepsy and Global Brain Atrophy.
Neurodegenerative Diseases
Low-frequency rTMS of the premotor cortex reduces complex movement patterns in a patient with pantothenate kinase-associated neurodegenerative disease (PKAN).
Neurodegenerative Diseases
Magnetic resonance imaging in pantothenate kinase-2-associated neurodegeneration.
Neurodegenerative Diseases
Novel homozygous PANK2 mutation identified in a consanguineous Chinese pedigree with pantothenate kinase-associated neurodegeneration.
Neurodegenerative Diseases
Overexpression of Human Mutant PANK2 Proteins Affects Development and Motor Behavior of Zebrafish Embryos.
Neurodegenerative Diseases
Pantethine rescues a Drosophila model for pantothenate kinase-associated neurodegeneration.
Neurodegenerative Diseases
Pantothenate kinase-associated neurodegeneration causing paradoxical vocal fold motion.
Neurodegenerative Diseases
Peroxynitrite production and activation of poly (adenosine diphosphate-ribose) synthetase in spinal cord injury.
Neurodegenerative Diseases
Siblings with the adult-onset slowly progressive type of pantothenate kinase-associated neurodegeneration and a novel mutation, Ile346Ser, in PANK2: clinical features and (99m)Tc-ECD brain perfusion SPECT findings.
Neurodegenerative Diseases
Skin fibroblasts from pantothenate kinase-associated neurodegeneration patients show altered cellular oxidative status and have defective iron-handling properties.
Neurodegenerative Diseases
The FOsmetpantotenate Replacement Therapy (FORT) randomized, double-blind, Placebo-controlled pivotal trial: Study design and development methodology of a novel primary efficacy outcome in patients with pantothenate kinase-associated neurodegeneration.
Neurodegenerative Diseases
Vitamin B5 (d-pantothenic acid) localizes in myelinated structures of the rat brain: Potential role for cerebral vitamin B5 stores in local myelin homeostasis.
Neurodegenerative Diseases
[Clinical characteristics and molecular pathogenesis of pantothenate kinase-associated neurodegenerative disease].
Neuroendocrine Tumors
Interferons in the management of neuroendocrine tumors and their possible mechanism of action.
Neuroinflammatory Diseases
Gedunin Inhibits Oligomeric A?1-42-Induced Microglia Activation Via Modulation of Nrf2-NF-?B Signaling.
Neuroinflammatory Diseases
Morphine Induces Apoptosis, Inflammation, and Mitochondrial Oxidative Stress via Activation of TRPM2 Channel and Nitric Oxide Signaling Pathways in the Hippocampus.
Neurologic Manifestations
[Lethal neonatal deficiency of carbamyl phosphate synthetase (author's transl)]
Newcastle Disease
INHIBITION OF RIBONUCLEIC ACID SYNTHETASE FROM INFLUENZA- AND NEWCASTLE DISEASE VIRUS-INFECTED CELLS BY VARIOUS ANTIVIRAL COMPOUNDS.
Newcastle Disease
Interferon inducibility and sensitivity of human teratocarcinoma-derived cell lines.
Nose Diseases
[THERAPEUTIC EFFECTIVENESS OF A NEW PREPARATION WITH A BASE OF MENTHYL PANTOTHENATE IN ACUTE AND CHRONIC NASAL DISEASES.]
Obesity
Effects of soy isoflavones on testosterone synthetase in diet-induced obesity male rats.
Obesity
Liver acetyl CoA carboxylase and fatty acid synthetase: relative activities in the normal state and in hereditary obesity.
Obesity
Metabolic dysfunction in pregnancy: Fingerprinting the maternal metabolome using proton nuclear magnetic resonance spectroscopy.
Obesity
Pathogenesis of obesity by food restriction in OLETF rats-increased intestinal monoacylglycerol acyltransferase activities may be a crucial factor.
Obesity
Ultra-fast simultaneous detection of obesity-related coenzymes in mice using microchip electrophoresis with a LIF detector.
Obesity
[Progress of researches on mechanisms of acupuncture therapy for insulin resistance].
Obesity, Abdominal
Abdominal obesity is associated with insulin resistance and reduced glycogen synthetase activity in skeletal muscle.
Oligospermia
Phosphoribosyl-pyrophosphate synthetase 2 (PRPS2) depletion regulates spermatogenic cell apoptosis and is correlated with hypospermatogenesis.
Optic Atrophy
Optic Atrophy in a Patient With Atypical Pantothenate Kinase-Associated Neurodegeneration.
ornithine carbamoyltransferase deficiency
Citrulline in health and disease. Review on human studies.
ornithine carbamoyltransferase deficiency
Improving long term outcomes in urea cycle disorders-report from the Urea Cycle Disorders Consortium.
ornithine carbamoyltransferase deficiency
Isolation of Hepatic Progenitor Cells From Human Liver With Cirrhosis Secondary to Biliary Atresia Using EpCAM or Thy-1 Markers.
ornithine carbamoyltransferase deficiency
N-acetylglutamate content in liver and gut of normal and fasted mice, normal human livers, and livers of individuals with carbamyl phosphate synthetase or ornithine transcarbamylase deficiency.
ornithine carbamoyltransferase deficiency
Prenatal diagnosis of ornithine transcarbamylase deficiency utilizing fetal liver biopsy.
ornithine carbamoyltransferase deficiency
Urea Cycle Disorders: A Neuroimaging Pattern Approach Using Diffusion and FLAIR MRI.
Ornithine Carbamoyltransferase Deficiency Disease
Citrulline in health and disease. Review on human studies.
Ornithine Carbamoyltransferase Deficiency Disease
Improving long term outcomes in urea cycle disorders-report from the Urea Cycle Disorders Consortium.
Ornithine Carbamoyltransferase Deficiency Disease
Isolation of Hepatic Progenitor Cells From Human Liver With Cirrhosis Secondary to Biliary Atresia Using EpCAM or Thy-1 Markers.
Ornithine Carbamoyltransferase Deficiency Disease
N-acetylglutamate content in liver and gut of normal and fasted mice, normal human livers, and livers of individuals with carbamyl phosphate synthetase or ornithine transcarbamylase deficiency.
Ornithine Carbamoyltransferase Deficiency Disease
Prenatal diagnosis of ornithine transcarbamylase deficiency utilizing fetal liver biopsy.
Ornithine Carbamoyltransferase Deficiency Disease
The phenotypic spectrum of organic acidurias and urea cycle disorders. Part 1: the initial presentation.
Osteoarthritis
Degenerative knee joint disease in mice lacking 3'-phosphoadenosine 5'-phosphosulfate synthetase 2 (Papss2) activity: a putative model of human PAPSS2 deficiency-associated arthrosis.
Osteoarthritis
Higher PGD2 production by synovial mast cells from rheumatoid arthritis patients compared with osteoarthritis patients via miR-199a-3p/prostaglandin synthetase 2 axis.
Osteolysis
Pharmaceutical inhibition of glycogen synthetase kinase 3 beta suppresses wear debris-induced osteolysis.
Osteoporosis
A Novel IFITM5 Variant Associated with Phenotype of Osteoporosis with Calvarial Doughnut Lesions: A Case Report.
Otitis Media
Host-derived sialic acid is incorporated into Haemophilus influenzae lipopolysaccharide and is a major virulence factor in experimental otitis media.
Ototoxicity
N-acetylcysteine and N-nitroarginine methyl ester attenuate Carboplatin-induced ototoxicity in dissociated spiral ganglion neuron cultures.
Ovarian Neoplasms
Rapid detection of exon 2-deleted AIMP2 mutation as a potential biomarker for lung cancer by molecular beacons.
Overweight
Efficacy of Slim339 in reducing body weight of overweight and obese human subjects.
Pancreatic Neoplasms
Evaluation of pyrimidine metabolising enzymes and in vitro uptake of 3'-[(18)F]fluoro-3'-deoxythymidine ([(18)F]FLT) in pancreatic cancer cell lines.
Pancreatic Neoplasms
LAT2 regulates glutamine-dependent mTOR activation to promote glycolysis and chemoresistance in pancreatic cancer.
Pancreatic Neoplasms
Metabolic effect of AOS-iron in rats with iron deficiency anemia using LC-MS/MS based metabolomics.
Pancreatitis
Green Tea Polyphenols Ameliorate Pancreatic Injury in Cerulein-Induced Murine Acute Pancreatitis.
pantoate-beta-alanine ligase (amp-forming) deficiency
-Glutamyl-cysteine synthetase deficiency. A cause of hereditary hemolytic anemia.
pantoate-beta-alanine ligase (amp-forming) deficiency
?1 -Pyrroline-5-carboxylate synthetase deficiency: An emergent multifaceted urea cycle-related disorder.
pantoate-beta-alanine ligase (amp-forming) deficiency
A case of carbamyl phosphate synthetase deficiency.
pantoate-beta-alanine ligase (amp-forming) deficiency
A novel mouse model for genetic variation in 10-formyltetrahydrofolate synthetase exhibits disturbed purine synthesis with impacts on pregnancy and embryonic development.
pantoate-beta-alanine ligase (amp-forming) deficiency
Acute administration of 5-oxoproline induces oxidative damage to lipids and proteins and impairs antioxidant defenses in cerebral cortex and cerebellum of young rats.
pantoate-beta-alanine ligase (amp-forming) deficiency
Alteration of urinary carnitine profile induced by benzoate administration.
pantoate-beta-alanine ligase (amp-forming) deficiency
Aminoacyl-tRNA synthetase deficiencies in search of common themes.
pantoate-beta-alanine ligase (amp-forming) deficiency
Arginine deficiency syndrome. Its occurrence in carbamyl phosphate synthetase deficiency.
pantoate-beta-alanine ligase (amp-forming) deficiency
Arginosuccinate synthetase deficiency: good outcome despite severe neonatal hyperammonaemia.
pantoate-beta-alanine ligase (amp-forming) deficiency
Atypical phenylketonuria caused by 7, 8-dihydrobiopterin synthetase deficiency.
pantoate-beta-alanine ligase (amp-forming) deficiency
Atypical phenylketonuria due to dihydrobiopterin synthetase deficiency.
pantoate-beta-alanine ligase (amp-forming) deficiency
Augmenting ureagenesis in patients with partial carbamyl phosphate synthetase 1 deficiency with N-carbamyl-L-glutamate.
pantoate-beta-alanine ligase (amp-forming) deficiency
Autosomal recessive inheritance of human mitochondrial carbamyl phosphate synthetase deficiency.
pantoate-beta-alanine ligase (amp-forming) deficiency
Biallelic IARS Mutations Cause Growth Retardation with Prenatal Onset, Intellectual Disability, Muscular Hypotonia, and Infantile Hepatopathy.
pantoate-beta-alanine ligase (amp-forming) deficiency
Blood cell glycogen synthetase activities in hepatic glycogen synthetase deficiency.
pantoate-beta-alanine ligase (amp-forming) deficiency
Brain glutamine by MRS in a patient with urea cycle disorder and coma.
pantoate-beta-alanine ligase (amp-forming) deficiency
Carbamyl phosphate synthetase deficiency and postpartum hyperammonemia.
pantoate-beta-alanine ligase (amp-forming) deficiency
Carbamyl phosphate synthetase deficiency with lethal neonatal outcome.
pantoate-beta-alanine ligase (amp-forming) deficiency
Central tegmental tract involvement in an infant with 6-pyruvoyltetrahydropterin synthetase deficiency.
pantoate-beta-alanine ligase (amp-forming) deficiency
Cerebral Vitamin B5 (D-Pantothenic Acid) Deficiency as a Potential Cause of Metabolic Perturbation and Neurodegeneration in Huntington's Disease.
pantoate-beta-alanine ligase (amp-forming) deficiency
Citrullinemia: prenatal diagnosis of an affected fetus.
pantoate-beta-alanine ligase (amp-forming) deficiency
Clinical consequences of enzyme deficiencies in the erythrocyte.
pantoate-beta-alanine ligase (amp-forming) deficiency
Correction of congenital erythropoietic porphyria by bone marrow transplantation.
pantoate-beta-alanine ligase (amp-forming) deficiency
Correction to: Correspondence on "AminoacyltRNA synthetase deficiencies in search of common themes" by Fuchs et al.
pantoate-beta-alanine ligase (amp-forming) deficiency
Correction: Aminoacyl-tRNA synthetase deficiencies in search of common themes.
pantoate-beta-alanine ligase (amp-forming) deficiency
Correspondence on "Aminoacyl-tRNA synthetase deficiencies in search of common themes" by Fuchs et al.
pantoate-beta-alanine ligase (amp-forming) deficiency
Disorders associated with purine and pyrimidine metabolism.
pantoate-beta-alanine ligase (amp-forming) deficiency
Disorders of purine and pyrimidine metabolism.
pantoate-beta-alanine ligase (amp-forming) deficiency
Early liver transplantation in neonatal-onset and moderate urea cycle disorders may lead to normal neurodevelopment.
pantoate-beta-alanine ligase (amp-forming) deficiency
Effect of malnutrition on susceptibility of rats to Trypanosoma cruzi. III. Pantothenate deficiency.
pantoate-beta-alanine ligase (amp-forming) deficiency
Effect of pantothenate deficiency on synthesis of adrenal cholesterol following stress.
pantoate-beta-alanine ligase (amp-forming) deficiency
Glucose homeostasis in adulthood and in pregnancy in a patient with hepatic glycogen synthetase deficiency.
pantoate-beta-alanine ligase (amp-forming) deficiency
Hemolytic anemia, recurrent metabolic acidosis, and incomplete albinism associated with glutathione synthetase deficiency.
pantoate-beta-alanine ligase (amp-forming) deficiency
Hepatic glycogen synthetase deficiency not expressed in cultured skin fibroblasts.
pantoate-beta-alanine ligase (amp-forming) deficiency
Hepatic glycogen synthetase deficiency.
pantoate-beta-alanine ligase (amp-forming) deficiency
Hepatic glycogen synthetase deficiency. Definition of syndrome from metabolic and enzyme studies on a 9-year-old girl.
pantoate-beta-alanine ligase (amp-forming) deficiency
Hepatic glycogen synthetase deficiency. Further studies on a family.
pantoate-beta-alanine ligase (amp-forming) deficiency
Lipoic acid synthetase deficiency causes neonatal-onset epilepsy, defective mitochondrial energy metabolism, and glycine elevation.
pantoate-beta-alanine ligase (amp-forming) deficiency
Long-term management of a case of carbamyl phosphate synthetase deficiency using ketanalogues and hydroxyanalogues of essential amino acids.
pantoate-beta-alanine ligase (amp-forming) deficiency
Low Dietary Folate Interacts with MTHFD1 Synthetase Deficiency in Mice, a Model for the R653Q Variant, to Increase Incidence of Developmental Delays and Defects.
pantoate-beta-alanine ligase (amp-forming) deficiency
Metabolic stroke in carbamyl phosphate synthetase deficiency.
pantoate-beta-alanine ligase (amp-forming) deficiency
Metabolism of nicotinic acid under normal conditions and in pantothenate deficiency, studied in the rat.
pantoate-beta-alanine ligase (amp-forming) deficiency
Methionine supplementation for multi-organ dysfunction in MetRS-related pulmonary alveolar proteinosis.
pantoate-beta-alanine ligase (amp-forming) deficiency
Mild pantothenate deficiency in rats elevates serum triglyceride and free fatty acid levels.
pantoate-beta-alanine ligase (amp-forming) deficiency
MTHFD1 formyltetrahydrofolate synthetase deficiency, a model for the MTHFD1 R653Q variant, leads to congenital heart defects in mice.
pantoate-beta-alanine ligase (amp-forming) deficiency
N-acetyl-glutamate synthetase deficiency or porto-systemic shunt associated encephalopathy?
pantoate-beta-alanine ligase (amp-forming) deficiency
Neonatal death due to carbamyl phosphate synthetase deficiency.
pantoate-beta-alanine ligase (amp-forming) deficiency
Neonatal hyperphenylalaninaemia presumably caused by a new variant of biopterin synthetase deficiency.
pantoate-beta-alanine ligase (amp-forming) deficiency
Normal N-acetylglutamate concentration measured in liver from a new patient with N-acetylglutamate synthetase deficiency: physiologic and biochemical implications.
pantoate-beta-alanine ligase (amp-forming) deficiency
Nutritional therapy for selected inborn errors of metabolism.
pantoate-beta-alanine ligase (amp-forming) deficiency
Orthotopic liver transplantation in a patient with carbamyl phosphate synthetase deficiency and cystic fibrosis.
pantoate-beta-alanine ligase (amp-forming) deficiency
Pantothenic acid in health and disease.
pantoate-beta-alanine ligase (amp-forming) deficiency
Partial carbamyl phosphate synthetase deficiency, simulating Reye's syndrome, in a 9-year-old girl.
pantoate-beta-alanine ligase (amp-forming) deficiency
Partial N-acetyl-glutamate synthetase deficiency masquerading as a valproic acid-induced Reye-like syndrome.
pantoate-beta-alanine ligase (amp-forming) deficiency
Patients with genetic defects in the gamma-glutamyl cycle.
pantoate-beta-alanine ligase (amp-forming) deficiency
Phenotypes and genotypes of mitochondrial aminoacyl-tRNA synthetase deficiencies from a single neurometabolic clinic.
pantoate-beta-alanine ligase (amp-forming) deficiency
Phenylacetylglutamine may replace urea as a vehicle for waste nitrogen excretion.
pantoate-beta-alanine ligase (amp-forming) deficiency
Pilot use of the early motor repertoire in infants with inborn errors of metabolism: Outcomes in early and middle childhood.
pantoate-beta-alanine ligase (amp-forming) deficiency
Postpartum "psychosis" in mild argininosuccinate synthetase deficiency.
pantoate-beta-alanine ligase (amp-forming) deficiency
Proceedings: Hepatic ultrastructure in a child with carbamyl phosphate synthetase deficiency, hyperornithinaemia, hyperammonaemia, and homocitrullinuria.
pantoate-beta-alanine ligase (amp-forming) deficiency
Prospective cohort study for identification of underlying genetic causes in neonatal encephalopathy using whole-exome sequencing.
pantoate-beta-alanine ligase (amp-forming) deficiency
Prospective versus clinical diagnosis and therapy of acute neonatal hyperammonaemia in two sisters with carbamyl phosphate synthetase deficiency.
pantoate-beta-alanine ligase (amp-forming) deficiency
Pterin metabolism in normal subjects and hyperphenylalaninaemic patients.
pantoate-beta-alanine ligase (amp-forming) deficiency
Pterins analysis in amniotic fluid for the prenatal diagnosis of GTP cyclohydrolase deficiency.
pantoate-beta-alanine ligase (amp-forming) deficiency
Resistance of rats to inoculation with Corynebacterium pathogenic in pantothenate deficiency.
pantoate-beta-alanine ligase (amp-forming) deficiency
Serotonin and dopamine synthesis in phenylketonuria.
pantoate-beta-alanine ligase (amp-forming) deficiency
Severe Neonatal Manifestations of Infantile Liver Failure Syndrome Type 1 Caused by Cytosolic Leucine-tRNA Synthetase Deficiency.
pantoate-beta-alanine ligase (amp-forming) deficiency
Significance of pantothenate for glucose fermentation by Oenococcus oeni and for suppression of the erythritol and acetate production.
pantoate-beta-alanine ligase (amp-forming) deficiency
The dietary treatment of hepatic glycogen synthetase deficiency.
pantoate-beta-alanine ligase (amp-forming) deficiency
The effect of pantothenate deficiency in mice on their metabolic response to fast and exercise.
pantoate-beta-alanine ligase (amp-forming) deficiency
The effect of pantothenate deficiency on Trypanosoma lewisi infection in the rat.
pantoate-beta-alanine ligase (amp-forming) deficiency
The effects of pantothenate deficiency and acetate addition on anaerobic batch fermentation of glucose by Saccharomyces cerevisiae.
pantoate-beta-alanine ligase (amp-forming) deficiency
The first successful live birth following preimplantation genetic diagnosis using PCR for type 1 citrullinemia.
pantoate-beta-alanine ligase (amp-forming) deficiency
The phenotypic spectrum of organic acidurias and urea cycle disorders. Part 1: the initial presentation.
pantoate-beta-alanine ligase (amp-forming) deficiency
Treatment of carbamyl phosphate synthetase deficiency with keto analogues of essential amino acids.
pantoate-beta-alanine ligase (amp-forming) deficiency
Urea Cycle Disorders: A Neuroimaging Pattern Approach Using Diffusion and FLAIR MRI.
pantoate-beta-alanine ligase (amp-forming) deficiency
[A case of citrullinemia associated with isolated ACTH deficiency, rapidly developing coma]
pantoate-beta-alanine ligase (amp-forming) deficiency
[A new inherited metabolic disease: delta1-pyrroline 5-carboxylate synthetase deficiency]
pantoate-beta-alanine ligase (amp-forming) deficiency
[Adrenal cortex functional activity in pantothenate deficiency and the administration of the vitamin or its derivatives]
pantoate-beta-alanine ligase (amp-forming) deficiency
[Congenital hyperammoniemia caused by ornithine carbamoyl-transferase and carbamyl phosphate synthetase deficiency]
pantoate-beta-alanine ligase (amp-forming) deficiency
[Diagnosis of deficiency in cofactor of phenylalanine hydroxylase: a metabolic emergency]
pantoate-beta-alanine ligase (amp-forming) deficiency
[Glycogenosis with probable glycogen synthetase deficiency in a 4-year-old boy]
pantoate-beta-alanine ligase (amp-forming) deficiency
[Hepatic glycogen synthetase deficiency or glycogen storage disease-zero. Mild phenotype with partial enzymatic defect]
pantoate-beta-alanine ligase (amp-forming) deficiency
[Hyperammonemia: partial carbamyl phosphate synthetase deficiency]
pantoate-beta-alanine ligase (amp-forming) deficiency
[Lethal neonatal deficiency of carbamyl phosphate synthetase (author's transl)]
pantoate-beta-alanine ligase (amp-forming) deficiency
[Liver coma with fatal course in 2 children under long-term antiepileptic therapy]
pantoate-beta-alanine ligase (amp-forming) deficiency
[Malignant phenylketonuria caused by biopterin synthetase deficiency. Study of neuromediator catabolites in the cerebrospinal fluid during treatment]
pantoate-beta-alanine ligase (amp-forming) deficiency
[Prenatal diagnosis of carbamyl phosphate synthetase deficiency by fetal liver biopsy]
pantoate-beta-alanine ligase (amp-forming) deficiency
[Remarks on a clinical case of partial carbamyl phosphate synthetase deficiency]
pantoate-beta-alanine ligase (amp-forming) deficiency
[Screening for newborn organic aciduria in Zhejiang province:prevalence, outcome and follow-up].
pantoate-beta-alanine ligase (amp-forming) deficiency
[The separate and combined effects of calcium pantothenate deficiency and cadmium intoxication on rat reproductive function].
pantoate-beta-alanine ligase (amp-forming) deficiency
[Therapy of hyperammonemia in carbamyl phosphate synthase deficiency with peritoneal dialysis and venovenous hemofiltration]
pantoate-beta-alanine ligase (amp-forming) deficiency
[Three congenital metabolic diseases in the Faeroe Islands. Incidence, clinical and molecular genetic characteristics of Faeroese children with glycogen storage disease type IIIA, carnitine transporter deficiency and holocarboxylase synthetase deficiency]
pantoate-beta-alanine ligase (amp-forming) deficiency
[Trial of indirect screening of tetrahydrobiopterin deficiency]
Pantothenate Kinase-Associated Neurodegeneration
123I-ioflupane SPECT findings of pantothenate kinase-associated neurodegeneration.
Pantothenate Kinase-Associated Neurodegeneration
4'-Phosphopantetheine corrects CoA, iron, and dopamine metabolic defects in mammalian models of PKAN.
Pantothenate Kinase-Associated Neurodegeneration
A new in vivo model of pantothenate kinase-associated neurodegeneration reveals a surprising role for transcriptional regulation in pathogenesis.
Pantothenate Kinase-Associated Neurodegeneration
A novel 3-bp deletion in the PANK2 gene of Dutch patients with pantothenate kinase-associated neurodegeneration: evidence for a founder effect.
Pantothenate Kinase-Associated Neurodegeneration
A novel gene mutation in PANK2 in a patient with an atypical form of pantothenate kinase-associated neurodegeneration.
Pantothenate Kinase-Associated Neurodegeneration
A novel gene mutation in PANK2 in a patient with severe jaw-opening dystonia.
Pantothenate Kinase-Associated Neurodegeneration
A novel homozygous variation in the PANK2 gene in two Persian siblings with atypical pantothenate kinase associated neurodegeneration.
Pantothenate Kinase-Associated Neurodegeneration
A novel mutation in a patient with pantothenate kinase-associated neurodegeneration.
Pantothenate Kinase-Associated Neurodegeneration
A Novel Nonsense Mutation in PANK2 Gene in Two Patients with Pantothenate Kinase-Associated Neurodegeneration.
Pantothenate Kinase-Associated Neurodegeneration
A novel PANK2 gene mutation: clinical and molecular characteristics of patients short communication.
Pantothenate Kinase-Associated Neurodegeneration
A novel PANK2 mutation in a 12-year-old Chinese boy with pantothenate kinase-associated neurodegeneration.
Pantothenate Kinase-Associated Neurodegeneration
A patient with pantothenate kinase-associated neurodegeneration and supranuclear gaze palsy.
Pantothenate Kinase-Associated Neurodegeneration
A pilot trial of deferiprone for neurodegeneration with brain iron accumulation.
Pantothenate Kinase-Associated Neurodegeneration
A pilot trial of deferiprone in pantothenate kinase-associated neurodegeneration patients.
Pantothenate Kinase-Associated Neurodegeneration
A Scale to Assess Activities of Daily Living in Pantothenate Kinase-Associated Neurodegeneration.
Pantothenate Kinase-Associated Neurodegeneration
A variation in PANK2 gene is causing Pantothenate kinase-associated Neurodegeneration in a family from Jammu and Kashmir - India.
Pantothenate Kinase-Associated Neurodegeneration
Abnormal Vasculature Development in Zebrafish Embryos with Reduced Expression of Pantothenate Kinase 2 Gene.
Pantothenate Kinase-Associated Neurodegeneration
Acanthocytosis and the c.680 A>G Mutation in the PANK2 Gene: A Study Enrolling a Cohort of PKAN Patients from the Dominican Republic.
Pantothenate Kinase-Associated Neurodegeneration
Aceruloplasminemia: Neurodegeneration with Brain Iron Accumulation (NBIA) associated with psychosis.
Pantothenate Kinase-Associated Neurodegeneration
All that glitters is not gold: When motor and vocal tics in a child do not match Tourette syndrome: A case report.
Pantothenate Kinase-Associated Neurodegeneration
Amantadine for Gait Dysfunction in Pantothenate Kinase-Associated Neurodegeneration.
Pantothenate Kinase-Associated Neurodegeneration
Amelioration of Dystonic Opisthotonus in Pantothenate Kinase-Associated Neurodegeneration Syndrome with Absent "Eye-of-the-Tiger" Sign Following Bilateral Pallidal Deep Brain Stimulation.
Pantothenate Kinase-Associated Neurodegeneration
An isoform of hPANK2, deficient in pantothenate kinase-associated neurodegeneration, localizes to mitochondria.
Pantothenate Kinase-Associated Neurodegeneration
Anticholinergic-responsive gait freezing in a patient with pantothenate kinase-associated neurodegeneration.
Pantothenate Kinase-Associated Neurodegeneration
Atypical pantothenate kinase-associated neurodegeneration with novel genetic mutation.
Pantothenate Kinase-Associated Neurodegeneration
Atypical pantothenate kinase-associated neurodegeneration with PANK2 mutations : clinical description and a review of the literature.
Pantothenate Kinase-Associated Neurodegeneration
Atypical pantothenate kinase-associated neurodegeneration with variable phenotypes in an Egyptian family.
Pantothenate Kinase-Associated Neurodegeneration
Atypical pantothenate kinase-associated neurodegeneration: Clinical description of two brothers and a review of the literature.
Pantothenate Kinase-Associated Neurodegeneration
Basal ganglia calcification and novel compound heterozygous mutations in the PANK2 gene in a Chinese boy with classic Pantothenate kinase-associated neurodegeneration: A case report.
Pantothenate Kinase-Associated Neurodegeneration
Beta-propeller protein-associated neurodegeneration (BPAN), a rare form of NBIA: Novel mutations and neuropsychiatric phenotype in three adult patients.
Pantothenate Kinase-Associated Neurodegeneration
Biochemical properties of human pantothenate kinase 2 isoforms and mutations linked to pantothenate kinase-associated neurodegeneration.
Pantothenate Kinase-Associated Neurodegeneration
Botulinum toxin in the treatment of sialorrhea.
Pantothenate Kinase-Associated Neurodegeneration
Botulinum toxin injection to improve functional independence and to alleviate parenting stress in a child with advanced pantothenate kinase-associated neurodegeneration: A case report and literature review.
Pantothenate Kinase-Associated Neurodegeneration
Botulinum Toxin-A Injection in the Treatment of Spasticity in a Infantile-Onset Neurodegeneration With Brain Iron Accumulation: A Case Report.
Pantothenate Kinase-Associated Neurodegeneration
Cannabis Use in Children With Pantothenate Kinase-Associated Neurodegeneration.
Pantothenate Kinase-Associated Neurodegeneration
Cerebral blood flow in dystonia due to pantothenate kinase-associated neurodegeneration.
Pantothenate Kinase-Associated Neurodegeneration
Changes in Cerebral Gray and White Matter in Patients with Pantothenate Kinase-Associated Neurodegeneration: A Long-Term Magnetic Resonance Imaging Follow-Up Study.
Pantothenate Kinase-Associated Neurodegeneration
Changes in Red Blood Cell membrane lipid composition: A new perspective into the pathogenesis of PKAN.
Pantothenate Kinase-Associated Neurodegeneration
Changes of cerebral white matter in patients suffering from Pantothenate Kinase-Associated Neurodegeneration (PKAN): A diffusion tensor imaging (DTI) study.
Pantothenate Kinase-Associated Neurodegeneration
Characteristic "Forcible" Geste Antagoniste in Oromandibular Dystonia Resulting From Pantothenate Kinase-Associated Neurodegeneration.
Pantothenate Kinase-Associated Neurodegeneration
Characterization of sleep in six patients with pantothenate kinase-associated neurodegeneration.
Pantothenate Kinase-Associated Neurodegeneration
Characterization of the human PANK2 promoter.
Pantothenate Kinase-Associated Neurodegeneration
Chasing shadows: What determines DTI metrics in gray matter regions? An in vitro and in vivo study.
Pantothenate Kinase-Associated Neurodegeneration
Childhood disorders of neurodegeneration with brain iron accumulation (NBIA).
Pantothenate Kinase-Associated Neurodegeneration
Clinical and genetic features of PKAN patients in a tertiary centre in Turkey.
Pantothenate Kinase-Associated Neurodegeneration
Clinical and molecular research of neuroacanthocytosis.
Pantothenate Kinase-Associated Neurodegeneration
Clinical and neuropsychological correlates in two brothers with pantothenate kinase-associated neurodegeneration.
Pantothenate Kinase-Associated Neurodegeneration
Clinical course of patients with pantothenate kinase-associated neurodegeneration (PKAN) before and after DBS surgery.
Pantothenate Kinase-Associated Neurodegeneration
CLINICAL EFFECT OF A MUTATION (p.Glu322Asp, c.966 G>T) IN PANK2 GENE IN A FAMILY WITH ATYPICAL PANTOTHENATE KINASE-ASSOCIATED NEURODEGENERATION.
Pantothenate Kinase-Associated Neurodegeneration
Clinical Heterogeneity of Atypical Pantothenate Kinase-Associated Neurodegeneration in Koreans.
Pantothenate Kinase-Associated Neurodegeneration
Clinical heterogeneity of neurodegeneration with brain iron accumulation (Hallervorden-Spatz syndrome) and pantothenate kinase-associated neurodegeneration.
Pantothenate Kinase-Associated Neurodegeneration
Clinical rating scale for pantothenate kinase-associated neurodegeneration: A pilot study.
Pantothenate Kinase-Associated Neurodegeneration
Clinical, imaging, and molecular findings in a sample of Mexican families with pantothenate kinase associated neurodegeneration.
Pantothenate Kinase-Associated Neurodegeneration
Coenzyme A corrects pathological defects in human neurons of PANK2-associated neurodegeneration.
Pantothenate Kinase-Associated Neurodegeneration
Consensus clinical management guideline for beta-propeller protein-associated neurodegeneration.
Pantothenate Kinase-Associated Neurodegeneration
Consensus clinical management guideline for pantothenate kinase-associated neurodegeneration (PKAN).
Pantothenate Kinase-Associated Neurodegeneration
Copper, Iron, and Manganese Toxicity in Neuropsychiatric Conditions.
Pantothenate Kinase-Associated Neurodegeneration
Current state of knowledge in Chorea-Acanthocytosis as core Neuroacanthocytosis syndrome.
Pantothenate Kinase-Associated Neurodegeneration
Cyclic Phosphopantothenic Acid Prodrugs for Treatment of Pantothenate Kinase-Associated Neurodegeneration.
Pantothenate Kinase-Associated Neurodegeneration
De novo CoA biosynthesis is required to maintain DNA integrity during development of the Drosophila nervous system.
Pantothenate Kinase-Associated Neurodegeneration
Declining Use of the Hallervorden-Spatz Disease Eponym in the Last Two Decades.
Pantothenate Kinase-Associated Neurodegeneration
Decreasing iron neurotoxicity in pantothenate kinase-associated neurodegeneration.
Pantothenate Kinase-Associated Neurodegeneration
Deep brain stimulation as a mode of treatment of early onset pantothenate kinase-associated neurodegeneration.
Pantothenate Kinase-Associated Neurodegeneration
Deep brain stimulation as treatment for dystonic storm in pantothenate kinase-associated neurodegeneration syndrome: case report of a patient with homozygous C.628 2 T?>?G mutation of the PANK2 gene.
Pantothenate Kinase-Associated Neurodegeneration
Deep brain stimulation for dystonia: a meta-analysis.
Pantothenate Kinase-Associated Neurodegeneration
Deep brain stimulation for pantothenate kinase-associated neurodegeneration.
Pantothenate Kinase-Associated Neurodegeneration
Deep brain stimulation for pantothenate kinase-associated neurodegeneration: A meta-analysis.
Pantothenate Kinase-Associated Neurodegeneration
Deep brain stimulation improves quality of life in pantothenate kinase-associated neurodegeneration.
Pantothenate Kinase-Associated Neurodegeneration
Deep brain stimulation in the globus pallidus compensates response inhibition deficits: evidence from pantothenate kinase-associated neurodegeneration.
Pantothenate Kinase-Associated Neurodegeneration
Deep brain stimulation in the management of pantothenate kinase-associated neurodegeneration: A missed or a new target?
Pantothenate Kinase-Associated Neurodegeneration
Deficiency of pantothenate kinase 2 (Pank2) in mice leads to retinal degeneration and azoospermia.
Pantothenate Kinase-Associated Neurodegeneration
Dental appliance therapy in pantothenate kinase-associated neurodegeneration: Case report.
Pantothenate Kinase-Associated Neurodegeneration
Deprivation of pantothenic acid elicits a movement disorder and azoospermia in a mouse model of pantothenate kinase-associated neurodegeneration.
Pantothenate Kinase-Associated Neurodegeneration
Diagnostic and clinical experience of patients with pantothenate kinase-associated neurodegeneration.
Pantothenate Kinase-Associated Neurodegeneration
Disorders of phospholipids, sphingolipids and fatty acids biosynthesis: toward a new category of inherited metabolic diseases.
Pantothenate Kinase-Associated Neurodegeneration
Down regulation of the expression of mitochondrial phosphopantetheinyl-proteins in pantothenate kinase-associated neurodegeneration: pathophysiological consequences and therapeutic perspectives.
Pantothenate Kinase-Associated Neurodegeneration
Early-onset neurodegeneration with brain iron accumulation due to PANK2 mutation.
Pantothenate Kinase-Associated Neurodegeneration
Efficacy and safety of deferiprone for the treatment of pantothenate kinase-associated neurodegeneration (PKAN) and neurodegeneration with brain iron accumulation (NBIA): Results from a four years follow-up.
Pantothenate Kinase-Associated Neurodegeneration
Electrophysiological assessment of the effect of intrathecal baclofen in dystonic children.
Pantothenate Kinase-Associated Neurodegeneration
Emerging Disease-Modifying Therapies in Neurodegeneration With Brain Iron Accumulation (NBIA) Disorders.
Pantothenate Kinase-Associated Neurodegeneration
Erratum to: Transcranial sonography in pantothenate kinase-associated neurodegeneration.
Pantothenate Kinase-Associated Neurodegeneration
Erratum: A new in vivo model of pantothenate kinase-associated neurodegeneration reveals a surprising role for transcriptional regulation in pathogenesis.
Pantothenate Kinase-Associated Neurodegeneration
Excess iron harms the brain: the syndromes of neurodegeneration with brain iron accumulation (NBIA).
Pantothenate Kinase-Associated Neurodegeneration
Exploring Yeast as a Study Model of Pantothenate Kinase-Associated Neurodegeneration and for the Identification of Therapeutic Compounds.
Pantothenate Kinase-Associated Neurodegeneration
Eye of the Tiger Sign in Pantothenate Kinase-Associated Neurodegeneration.
Pantothenate Kinase-Associated Neurodegeneration
Eye-of-the-tiger Sign in Neurodegeneration with Brain Iron Accumulation.
Pantothenate Kinase-Associated Neurodegeneration
Eye-of-the-Tiger sign is not Pathognomonic of Pantothenate Kinase-Associated Neurodegeneration in Adult Cases.
Pantothenate Kinase-Associated Neurodegeneration
First cases in the Czech Republic of the Hallervorden-Spatz disease resulting from mutation in the pantothenate kinase 2 gene.
Pantothenate Kinase-Associated Neurodegeneration
First report of co-morbidity of pantothenate kinase-associated neurodegeneration and three types of chronic hemolytic anemias.
Pantothenate Kinase-Associated Neurodegeneration
First successful trial of preimplantation genetic diagnosis for pantothenate kinase-associated neurodegeneration.
Pantothenate Kinase-Associated Neurodegeneration
Fosmetpantotenate (RE-024), a phosphopantothenate replacement therapy for pantothenate kinase-associated neurodegeneration: Mechanism of action and efficacy in nonclinical models.
Pantothenate Kinase-Associated Neurodegeneration
Fosmetpantotenate Randomized Controlled Trial in Pantothenate Kinase-Associated Neurodegeneration.
Pantothenate Kinase-Associated Neurodegeneration
Gene symbol: PANK2. Disease: Pantothenate kinase associated neurodegeneration (PKAN).
Pantothenate Kinase-Associated Neurodegeneration
Gene symbol: PANK2. Disease: pantothenate kinase-associated neurodegeneration (PKAN).
Pantothenate Kinase-Associated Neurodegeneration
Genetic heterogeneity in patients with pantothenate kinase-associated neurodegeneration and classic magnetic resonance imaging eye-of-the-tiger pattern.
Pantothenate Kinase-Associated Neurodegeneration
Genetic, clinical, and imaging characterization of one patient with late-onset, slowly progressive, pantothenate kinase-associated neurodegeneration.
Pantothenate Kinase-Associated Neurodegeneration
Genetic, clinical, and radiographic delineation of Hallervorden-Spatz syndrome.
Pantothenate Kinase-Associated Neurodegeneration
Genetics and Pathophysiology of Neurodegeneration with Brain Iron Accumulation (NBIA).
Pantothenate Kinase-Associated Neurodegeneration
Grey matter alterations in patients with Pantothenate Kinase-Associated Neurodegeneration (PKAN).
Pantothenate Kinase-Associated Neurodegeneration
Hallervorden-Spatz Syndrome with Seizures.
Pantothenate Kinase-Associated Neurodegeneration
Harmful Iron-Calcium Relationship in Pantothenate kinase Associated Neurodegeneration.
Pantothenate Kinase-Associated Neurodegeneration
HARP syndrome is allelic with pantothenate kinase-associated neurodegeneration.
Pantothenate Kinase-Associated Neurodegeneration
Idiopathic Basal Ganglia Calcifications: An Atypical Presentation of PKAN.
Pantothenate Kinase-Associated Neurodegeneration
Impaired Coenzyme A metabolism affects histone and tubulin acetylation in Drosophila and human cell models of pantothenate kinase associated neurodegeneration.
Pantothenate Kinase-Associated Neurodegeneration
Inborn errors of coenzyme A metabolism and neurodegeneration.
Pantothenate Kinase-Associated Neurodegeneration
Induction of Neuron-Specific Degradation of Coenzyme A Models Pantothenate Kinase-Associated Neurodegeneration by Reducing Motor Coordination in Mice.
Pantothenate Kinase-Associated Neurodegeneration
Infantile neuroaxonal dystrophy and pantothenate-kinase-associated neurodegeneration: locus heterogeneity.
Pantothenate Kinase-Associated Neurodegeneration
Influence of the Plant Extract Complex "AdMax" on Global Gene Expression Levels in Cultured Human Fibroblasts.
Pantothenate Kinase-Associated Neurodegeneration
Intellectual and adaptive behaviour functioning in pantothenate kinase-associated neurodegeneration.
Pantothenate Kinase-Associated Neurodegeneration
Intellectual Disability, Falls and Gait Disturbances: A Misdiagnosis.
Pantothenate Kinase-Associated Neurodegeneration
Involvement of Globus Pallidus and Midbrain Nuclei in Pantothenate Kinase-Associated Neurodegeneration : Measurement of T2 and T2* Time.
Pantothenate Kinase-Associated Neurodegeneration
Iron Accumulation in Syndromes of Neurodegeneration with Brain Iron Accumulation 1 and 2 - causative or consequential?
Pantothenate Kinase-Associated Neurodegeneration
Iron chelation in pantothenate kinase-associated neurodegeneration: A possible new avenue for slowing down disease progression in neurodegeneration.
Pantothenate Kinase-Associated Neurodegeneration
Iron chelation in the treatment of neurodegenerative diseases.
Pantothenate Kinase-Associated Neurodegeneration
Iron-related MRI images in patients with pantothenate kinase-associated neurodegeneration (PKAN) treated with deferiprone: Results of a phase II pilot trial.
Pantothenate Kinase-Associated Neurodegeneration
Long-lasting isolated freezing of gait with good response to methylphenidate: A patient with pantothenate kinase-associated neurodegeneration.
Pantothenate Kinase-Associated Neurodegeneration
Long-term benefit to pallidal deep brain stimulation in a case of dystonia secondary to pantothenate kinase-associated neurodegeneration.
Pantothenate Kinase-Associated Neurodegeneration
Looking Deep into the Eye-of-the-Tiger in Pantothenate Kinase-Associated Neurodegeneration.
Pantothenate Kinase-Associated Neurodegeneration
Magnetic resonance imaging pattern recognition in childhood bilateral basal ganglia disorders.
Pantothenate Kinase-Associated Neurodegeneration
Magnetic resonance imaging, susceptibility weighted imaging and quantitative susceptibility mapping findings of pantothenate kinase-associated neurodegeneration.
Pantothenate Kinase-Associated Neurodegeneration
Management of status dystonicus: our experience and review of the literature.
Pantothenate Kinase-Associated Neurodegeneration
Measurement of brain iron distribution in Hallevorden-Spatz syndrome.
Pantothenate Kinase-Associated Neurodegeneration
Metabolic consequences of mitochondrial coenzyme A deficiency in patients with PANK2 mutations.
Pantothenate Kinase-Associated Neurodegeneration
Metabolism and energy requirements in pantothenate kinase-associated neurodegeneration.
Pantothenate Kinase-Associated Neurodegeneration
Missense PANK2 mutation without "Eye of the tiger" sign: MR findings in a large group of patients with pantothenate kinase-associated neurodegeneration (PKAN).
Pantothenate Kinase-Associated Neurodegeneration
Mitochondrial iron and energetic dysfunction distinguish fibroblasts and induced neurons from pantothenate kinase-associated neurodegeneration patients.
Pantothenate Kinase-Associated Neurodegeneration
Mitochondrial localization of human PANK2 and hypotheses of secondary iron accumulation in pantothenate kinase-associated neurodegeneration.
Pantothenate Kinase-Associated Neurodegeneration
Movement disorders in mitochondrial diseases.
Pantothenate Kinase-Associated Neurodegeneration
MR relaxometry and 1H MR spectroscopy for the determination of iron and metabolite concentrations in PKAN patients.
Pantothenate Kinase-Associated Neurodegeneration
MRI, MR spectroscopy, and diffusion tensor imaging findings in patient with static encephalopathy of childhood with neurodegeneration in adulthood (SENDA).
Pantothenate Kinase-Associated Neurodegeneration
Mutations in the pantothenate kinase gene PANK2 are not associated with Parkinson disease.
Pantothenate Kinase-Associated Neurodegeneration
Natural history and genotype-phenotype correlation of pantothenate kinase-associated neurodegeneration.
Pantothenate Kinase-Associated Neurodegeneration
Neuro-ophthalmologic and electroretinographic findings in pantothenate kinase-associated neurodegeneration (formerly Hallervorden-Spatz syndrome).
Pantothenate Kinase-Associated Neurodegeneration
Neuroacanthocytosis in china: a review of published reports.
Pantothenate Kinase-Associated Neurodegeneration
Neuroacanthocytosis: a case report of chorea-acanthocytosis.
Pantothenate Kinase-Associated Neurodegeneration
Neurodegeneration with brain iron accumulation in an eleven-year-old jamaican male.
Pantothenate Kinase-Associated Neurodegeneration
Neurodegeneration with brain iron accumulation.
Pantothenate Kinase-Associated Neurodegeneration
Neurodegeneration with brain iron accumulation: A case report.
Pantothenate Kinase-Associated Neurodegeneration
Neurodegeneration with brain iron accumulation: A cautionary tale.
Pantothenate Kinase-Associated Neurodegeneration
Neurodegeneration with brain iron accumulation: Characterization of clinical, radiological, and genetic features of pediatric patients from Southern India.
Pantothenate Kinase-Associated Neurodegeneration
Neurologic phenotypes associated with acanthocytosis.
Pantothenate Kinase-Associated Neurodegeneration
Neuromodulation for neurodegenerative conditions.
Pantothenate Kinase-Associated Neurodegeneration
Neuromodulation in dystonia: current aspects of deep brain stimulation.
Pantothenate Kinase-Associated Neurodegeneration
Neuronal Ablation of CoA Synthase Causes Motor Deficits, Iron Dyshomeostasis, and Mitochondrial Dysfunctions in a CoPAN Mouse Model.
Pantothenate Kinase-Associated Neurodegeneration
Neuropathology and pathogenesis of extrapyramidal movement disorders: a critical update-I. Hypokinetic-rigid movement disorders.
Pantothenate Kinase-Associated Neurodegeneration
Neuropsychological functions and psychiatric symptoms in late-onset manifestation of pantothenate kinase-associated neurodegeneration: a clinical case report.
Pantothenate Kinase-Associated Neurodegeneration
New Perspectives in Iron Chelation Therapy for the Treatment of Neurodegenerative Diseases.
Pantothenate Kinase-Associated Neurodegeneration
Nigropallidal iron accumulation in pantothenate kinase-associated neurodegeneration demonstrated by susceptibility-weighted imaging.
Pantothenate Kinase-Associated Neurodegeneration
Novel compound heterozygous mutations in the PANK2 gene in a Chinese patient with atypical pantothenate kinase-associated neurodegeneration.
Pantothenate Kinase-Associated Neurodegeneration
Novel compound heterozygous mutations in the pantothenate kinase 2 gene in a korean patient with atypical pantothenate kinase associated neurodegeneration.
Pantothenate Kinase-Associated Neurodegeneration
Novel compound heterozygous PANK2 gene mutations in a Chinese patient with atypical pantothenate kinase-associated neurodegeneration.
Pantothenate Kinase-Associated Neurodegeneration
Novel gene mutations and clinical features in patients with pantothenate kinase-associated neurodegeneration.
Pantothenate Kinase-Associated Neurodegeneration
Novel histopathologic findings in molecularly-confirmed pantothenate kinase-associated neurodegeneration.
Pantothenate Kinase-Associated Neurodegeneration
Novel homozygous PANK2 mutation causing atypical pantothenate kinase-associated neurodegeneration (PKAN) in a Cypriot family.
Pantothenate Kinase-Associated Neurodegeneration
Novel homozygous PANK2 mutation identified in a consanguineous Chinese pedigree with pantothenate kinase-associated neurodegeneration.
Pantothenate Kinase-Associated Neurodegeneration
Novel mutation in the PANK2 gene leads to pantothenate kinase-associated neurodegeneration in a Pakistani family.
Pantothenate Kinase-Associated Neurodegeneration
Novel PANK2 gene mutations in korean patient with pantothenate kinase-associated neurodegeneration presenting unilateral dystonic tremor.
Pantothenate Kinase-Associated Neurodegeneration
Novel PANK2 gene mutations in two Chinese siblings with atypical pantothenate kinase-associated neurodegeneration.
Pantothenate Kinase-Associated Neurodegeneration
Novel PANK2 mutation discovered among South East Asian children living in Thailand affected with pantothenate kinase associated neurodegeneration.
Pantothenate Kinase-Associated Neurodegeneration
Novel PANK2 mutation in a Chinese boy with PANK2-associated neurodegeneration: A case report and review of Chinese cases.
Pantothenate Kinase-Associated Neurodegeneration
Open-Label Fosmetpantotenate, a Phosphopantothenate Replacement Therapy in a Single Patient with Atypical PKAN.
Pantothenate Kinase-Associated Neurodegeneration
Optic Atrophy in a Patient With Atypical Pantothenate Kinase-Associated Neurodegeneration.
Pantothenate Kinase-Associated Neurodegeneration
Overexpression of Human Mutant PANK2 Proteins Affects Development and Motor Behavior of Zebrafish Embryos.
Pantothenate Kinase-Associated Neurodegeneration
Pallidal neuronal apolipoprotein E in pantothenate kinase-associated neurodegeneration recapitulates ischemic injury to the globus pallidus.
Pantothenate Kinase-Associated Neurodegeneration
Pallidal stimulation for dystonia in pantothenate kinase-associated neurodegeneration.
Pantothenate Kinase-Associated Neurodegeneration
Pallidal stimulation for pantothenate kinase-associated neurodegeneration dystonia.
Pantothenate Kinase-Associated Neurodegeneration
Pallidal stimulation improves pantothenate kinase-associated neurodegeneration.
Pantothenate Kinase-Associated Neurodegeneration
Pallidal stimulation in atypical pantothenate kinase-associated neurodegeneration: six-year follow-up.
Pantothenate Kinase-Associated Neurodegeneration
Pallidal stimulation in siblings with pantothenate kinase-associated neurodegeneration: Four-year follow-up.
Pantothenate Kinase-Associated Neurodegeneration
PANK2 mutation screening recommended to confirm diagnosis of pantothenate kinase-associated neurodegeneration.
Pantothenate Kinase-Associated Neurodegeneration
Pantethine rescues a Drosophila model for pantothenate kinase-associated neurodegeneration.
Pantothenate Kinase-Associated Neurodegeneration
Pantethine treatment is effective in recovering the disease phenotype induced by ketogenic diet in a pantothenate kinase-associated neurodegeneration mouse model.
Pantothenate Kinase-Associated Neurodegeneration
Pantothenate kinase-associated neurodegeneration (formerly Hallervorden-Spatz syndrome).
Pantothenate Kinase-Associated Neurodegeneration
Pantothenate kinase-associated neurodegeneration (Hallervorden-Spatz syndrome).
Pantothenate Kinase-Associated Neurodegeneration
Pantothenate kinase-associated neurodegeneration (PKAN) and PLA2G6-associated neurodegeneration (PLAN): review of two major neurodegeneration with brain iron accumulation (NBIA) phenotypes.
Pantothenate Kinase-Associated Neurodegeneration
Pantothenate kinase-associated neurodegeneration (PKAN) in a child with Down syndrome. A case report and follow-up with MRI.
Pantothenate Kinase-Associated Neurodegeneration
Pantothenate kinase-associated neurodegeneration (PKAN): molecular confirmation of a Turkish patient with a rare frameshift mutation in the coding region of the PANK2 gene.
Pantothenate Kinase-Associated Neurodegeneration
Pantothenate kinase-associated neurodegeneration causing paradoxical vocal fold motion.
Pantothenate Kinase-Associated Neurodegeneration
Pantothenate kinase-associated neurodegeneration in Korea: recurrent R440P mutation in PANK2 and outcome of deep brain stimulation.
Pantothenate Kinase-Associated Neurodegeneration
Pantothenate kinase-associated neurodegeneration in two Chinese children: identification of a novel PANK2 gene mutation.
Pantothenate Kinase-Associated Neurodegeneration
Pantothenate kinase-associated neurodegeneration in two Taiwanese siblings: identification of a novel PANK2 gene mutation.
Pantothenate Kinase-Associated Neurodegeneration
Pantothenate kinase-associated neurodegeneration initially presenting as postural tremor alone in a Japanese family with homozygous N245S substitutions in the pantothenate kinase gene.
Pantothenate Kinase-Associated Neurodegeneration
Pantothenate kinase-associated neurodegeneration is not a synucleinopathy.
Pantothenate Kinase-Associated Neurodegeneration
Pantothenate kinase-associated neurodegeneration mimicking Tourette syndrome: a case report and review of the literature.
Pantothenate Kinase-Associated Neurodegeneration
Pantothenate kinase-associated neurodegeneration with increased lentiform nuclei cerebral blood flow.
Pantothenate Kinase-Associated Neurodegeneration
Pantothenate kinase-associated neurodegeneration.
Pantothenate Kinase-Associated Neurodegeneration
Pantothenate kinase-associated neurodegeneration: altered mitochondria membrane potential and defective respiration in Pank2 knock-out mouse model.
Pantothenate Kinase-Associated Neurodegeneration
Pantothenate kinase-associated neurodegeneration: Clinical aspects, diagnosis and treatments.
Pantothenate Kinase-Associated Neurodegeneration
Pantothenate kinase-associated neurodegeneration: Clinical description of 10 patients and identification of new mutations.
Pantothenate Kinase-Associated Neurodegeneration
Pantothenate kinase-associated neurodegeneration: insights from a Drosophila model.
Pantothenate Kinase-Associated Neurodegeneration
Pantothenate kinase-associated neurodegeneration: MR imaging, proton MR spectroscopy, and diffusion MR imaging findings.
Pantothenate Kinase-Associated Neurodegeneration
Pantothenate kinase-associated neurodegeneration: novel mutations in the PANK2 gene in an Argentinean young woman.
Pantothenate Kinase-Associated Neurodegeneration
Pantothenate Rescues Iron Accumulation in Pantothenate Kinase-Associated Neurodegeneration Depending on the Type of Mutation.
Pantothenate Kinase-Associated Neurodegeneration
Parkinson's Disease and Metal Storage Disorders: A Systematic Review.
Pantothenate Kinase-Associated Neurodegeneration
Partial deficit of pantothenate kinase 2 catalytic activity in a case of tremor-predominant neurodegeneration with brain iron accumulation.
Pantothenate Kinase-Associated Neurodegeneration
Pathophysiology and treatment of neurodegeneration with brain iron accumulation in the pediatric population.
Pantothenate Kinase-Associated Neurodegeneration
Phenotypes and genotypes of patients with pantothenate kinase-associated neurodegeneration in Asian and Caucasian populations: 2 cases and literature review.
Pantothenate Kinase-Associated Neurodegeneration
Pilot trial on the efficacy and safety of pantethine in children with pantothenate kinase-associated neurodegeneration: a single-arm, open-label study.
Pantothenate Kinase-Associated Neurodegeneration
Potential Treatment of Retinal Diseases with Iron Chelators.
Pantothenate Kinase-Associated Neurodegeneration
Precision medicine in pantothenate kinase-associated neurodegeneration.
Pantothenate Kinase-Associated Neurodegeneration
Progressive dystonia in a 12-year-old boy.
Pantothenate Kinase-Associated Neurodegeneration
Psychiatric symptoms in an adolescent reveal a novel compound heterozygous mutation of the PANK2 gene in the atypical PKAN syndrome.
Pantothenate Kinase-Associated Neurodegeneration
Rational Design of Novel Therapies for Pantothenate Kinase-Associated Neurodegeneration.
Pantothenate Kinase-Associated Neurodegeneration
Retinal iron homeostasis in health and disease.
Pantothenate Kinase-Associated Neurodegeneration
Retinitis pigmentosa in pantothenate kinase-associated neurodegeneration.
Pantothenate Kinase-Associated Neurodegeneration
Role of iron in neurodegenerative disorders.
Pantothenate Kinase-Associated Neurodegeneration
Safety and efficacy of deferiprone for pantothenate kinase-associated neurodegeneration: a randomised, double-blind, controlled trial and an open-label extension study.
Pantothenate Kinase-Associated Neurodegeneration
Sensory Tricks in Pantothenate Kinase-Associated Neurodegeneration: Video-Analysis of 43 Patients.
Pantothenate Kinase-Associated Neurodegeneration
Sequence Variations in Mitochondrial Ferritin: Distribution in Healthy Controls and Different Types of Patients.
Pantothenate Kinase-Associated Neurodegeneration
Severe tongue protrusion dystonia: clinical syndromes and possible treatment.
Pantothenate Kinase-Associated Neurodegeneration
Siblings with the adult-onset slowly progressive type of pantothenate kinase-associated neurodegeneration and a novel mutation, Ile346Ser, in PANK2: clinical features and (99m)Tc-ECD brain perfusion SPECT findings.
Pantothenate Kinase-Associated Neurodegeneration
Skin fibroblasts from pantothenate kinase-associated neurodegeneration patients show altered cellular oxidative status and have defective iron-handling properties.
Pantothenate Kinase-Associated Neurodegeneration
Sleep in genetically confirmed pantothenate kinase-associated neurodegeneration: a video-polysomnographic study.
Pantothenate Kinase-Associated Neurodegeneration
Status dystonicus in pantothenate kinase-associated neurodegeneration due to internal pulse generator depletion: Case study and literature review.
Pantothenate Kinase-Associated Neurodegeneration
Subthalamic Nuclei Stimulation in Patients With Pantothenate Kinase-Associated Neurodegeneration (PKAN).
Pantothenate Kinase-Associated Neurodegeneration
Surgery for other movement disorders: dystonia, tics.
Pantothenate Kinase-Associated Neurodegeneration
Susceptibility-weighted imaging in pantothenate kinase-associated neurodegeneration.
Pantothenate Kinase-Associated Neurodegeneration
Syndromes of neurodegeneration with brain iron accumulation.
Pantothenate Kinase-Associated Neurodegeneration
T2* and FSE MRI distinguishes four subtypes of neurodegeneration with brain iron accumulation.
Pantothenate Kinase-Associated Neurodegeneration
The "Eye-of-the-Tiger" Sign may be Absent in the Early Stages of Classic Pantothenate Kinase Associated Neurodegeneration.
Pantothenate Kinase-Associated Neurodegeneration
The Case of a Patient with Pantothenate Kinase-Associated Neurodegeneration Presenting with a Prolonged History of Stuttering Speech and a Misdiagnosis of Parkinson's Disease.
Pantothenate Kinase-Associated Neurodegeneration
The diverse phenotype and genotype of pantothenate kinase-associated neurodegeneration.
Pantothenate Kinase-Associated Neurodegeneration
The eye-of-the-tiger sign is not a reliable disease marker for Hallervorden-Spatz syndrome.
Pantothenate Kinase-Associated Neurodegeneration
The FOsmetpantotenate Replacement Therapy (FORT) randomized, double-blind, Placebo-controlled pivotal trial: Study design and development methodology of a novel primary efficacy outcome in patients with pantothenate kinase-associated neurodegeneration.
Pantothenate Kinase-Associated Neurodegeneration
The History of Deferiprone (L1) and the Paradigm of the Complete Treatment of Iron Overload in Thalassaemia.
Pantothenate Kinase-Associated Neurodegeneration
The neuropsychiatry of neuroacanthocytosis syndromes.
Pantothenate Kinase-Associated Neurodegeneration
The synthesis of minds and molecules leads to potential therapy for pantothenate kinase-associated neurodegeneration.
Pantothenate Kinase-Associated Neurodegeneration
Tongue Protrusion Dystonia in Pantothenate Kinase-Associated Neurodegeneration.
Pantothenate Kinase-Associated Neurodegeneration
Transcranial sonography in pantothenate kinase-associated neurodegeneration.
Pantothenate Kinase-Associated Neurodegeneration
Treatment of Classic Pantothenate Kinase-Associated Neurodegeneration with Deferiprone and Intrathecal Baclofen.
Pantothenate Kinase-Associated Neurodegeneration
Treatment Responsiveness of Parkinsonism in Atypical Pantothenate Kinase-Associated Neurodegeneration.
Pantothenate Kinase-Associated Neurodegeneration
Tremor-Dominant Pantothenate Kinase-associated Neurodegeneration.
Pantothenate Kinase-Associated Neurodegeneration
Turnover rate of coenzyme A in mouse brain and liver.
Pantothenate Kinase-Associated Neurodegeneration
Unraveling the Hallervorden-Spatz syndrome: pantothenate kinase-associated neurodegeneration is the name.
Pantothenate Kinase-Associated Neurodegeneration
Untangling the Thorns: Advances in the Neuroacanthocytosis Syndromes.
Pantothenate Kinase-Associated Neurodegeneration
Update on neurodegeneration with brain iron accumulation.
Pantothenate Kinase-Associated Neurodegeneration
[Anesthesia in patients with NBIA : Neurodegeneration with brain iron accumulation].
Pantothenate Kinase-Associated Neurodegeneration
[From the Hallervorden-Spatz eponym to the molecular terminology].
Pantothenate Kinase-Associated Neurodegeneration
[Mandibular fracture in a patient with pantothenate kinase-associated neurodegeneration (Hallervorden-Spatz syndrome)].
Pantothenate Kinase-Associated Neurodegeneration
[Pedigree analysis of C19ORF12 p.Asp18Tyr mutation in a family with mitochondrial membrane protein associated neurodegeneration].
Pantothenate Kinase-Associated Neurodegeneration
[Phenotypic and genotypic features of twenty children with classic pantothenate kinase-associated neurodegeneration].
Pantothenate Kinase-Associated Neurodegeneration
[«A most strange instance of illness in several siblings» - first description of a rare neurological disease in 1830?].
Papilloma
(2'-5')oligo(A) synthetase as a monitor of interferon action in juvenile laryngeal papillomatosis.
Paralysis
A patient with pantothenate kinase-associated neurodegeneration and supranuclear gaze palsy.
Paralysis
Neuropathology and pathogenesis of extrapyramidal movement disorders: a critical update-I. Hypokinetic-rigid movement disorders.
Paralysis
Structural studies on the inactivation of gamma-glutamylcysteine synthetase by the disulphide analogues of radioprotective cysteamine derivatives. Effects of aminoalkyl and hydroxyalkyl chain length and beta beta-bis-dimethylation.
Paraneoplastic Syndromes
Anti-EJ Antibody-positive Anti-synthetase Syndrome Associated with Retroperitoneal Sarcoma.
Parkinson Disease
A Scale to Assess Activities of Daily Living in Pantothenate Kinase-Associated Neurodegeneration.
Parkinson Disease
Identification of far upstream element-binding protein-1 as an authentic Parkin substrate.
Parkinson Disease
Mutations in the pantothenate kinase gene PANK2 are not associated with Parkinson disease.
Parkinson Disease
New Perspectives in Iron Chelation Therapy for the Treatment of Neurodegenerative Diseases.
Parkinson Disease
Sequence Variations in Mitochondrial Ferritin: Distribution in Healthy Controls and Different Types of Patients.
Parkinson Disease
The Case of a Patient with Pantothenate Kinase-Associated Neurodegeneration Presenting with a Prolonged History of Stuttering Speech and a Misdiagnosis of Parkinson's Disease.
Parkinsonian Disorders
4'-Phosphopantetheine corrects CoA, iron, and dopamine metabolic defects in mammalian models of PKAN.
Parkinsonian Disorders
A patient with pantothenate kinase-associated neurodegeneration and supranuclear gaze palsy.
Parkinsonian Disorders
A pilot trial of deferiprone for neurodegeneration with brain iron accumulation.
Parkinsonian Disorders
Mutations in the pantothenate kinase gene PANK2 are not associated with Parkinson disease.
Parkinsonian Disorders
Parkinson's Disease and Metal Storage Disorders: A Systematic Review.
Parkinsonian Disorders
Treatment Responsiveness of Parkinsonism in Atypical Pantothenate Kinase-Associated Neurodegeneration.
Perinatal Death
DNA constructs designed to produce short hairpin, interfering RNAs in transgenic mice sometimes show early lethality and an interferon response.
Periodontal Diseases
Biochemical alterations in inflammatory periodontal diseases I. Poly (ADP-ribose) synthetase activity in gingiva and gingival fibroblasts from humans with periodontitis.
Periodontitis
Biochemical alterations in inflammatory periodontal diseases I. Poly (ADP-ribose) synthetase activity in gingiva and gingival fibroblasts from humans with periodontitis.
Peripheral Nerve Injuries
Koumine enhances spinal cord 3?-hydroxysteroid oxidoreductase expression and activity in a rat model of neuropathic pain.
Peripheral Nervous System Diseases
Alternative stable conformation capable of protein misinteraction links tRNA synthetase to peripheral neuropathy.
Peripheral Nervous System Diseases
Clinical, neurophysiological and morphological study of dominant intermediate Charcot-Marie-Tooth type C neuropathy.
Peripheral Nervous System Diseases
Disorders of phospholipids, sphingolipids and fatty acids biosynthesis: toward a new category of inherited metabolic diseases.
Peripheral Nervous System Diseases
Drosophila as a platform to predict the pathogenicity of novel aminoacyl-tRNA synthetase mutations in CMT.
Peripheral Nervous System Diseases
tRNA overexpression rescues peripheral neuropathy caused by mutations in tRNA synthetase.
Peritonitis
Changes of hepatic sinusoids in experimental septicemia of rats are correlated with the production of nitrogen monoxide. A morphometrical and immunohistochemical study.
Peritonitis
Protective effect of poly(ADP-ribose) synthetase inhibition on multiple organ failure after zymosan-induced peritonitis in the rat.
Persistent Infection
Altered tissue distribution of viral replication and T cell spreading is pivotal in the protection against fatal lymphocytic choriomeningitis in mice after neutralization of IFN-alpha/beta.
Persistent Infection
Role of interferon in persistent infection of macrophages with herpes simplex virus.
Persistent Infection
Suppression of interferon-induced oligo-2',5'-adenylate synthetase induction in persistent infection.
Phenylketonurias
Atypical phenylketonuria caused by 7, 8-dihydrobiopterin synthetase deficiency.
Phenylketonurias
Central tegmental tract involvement in an infant with 6-pyruvoyltetrahydropterin synthetase deficiency.
Phenylketonurias
Effect of phenylpyruvate on enzymes involved in fatty acid synthesis in rat brain.
Phenylketonurias
Neonatal hyperphenylalaninaemia presumably caused by a new variant of biopterin synthetase deficiency.
Phenylketonurias
[Atypical form of phenylketonuria caused by lack of dihydrobiopterin synthetase activity]
Phenylketonurias
[Malignant phenylketonuria caused by biopterin synthetase deficiency. Study of neuromediator catabolites in the cerebrospinal fluid during treatment]
Pheochromocytoma
Decrease in the level of poly(ADP-ribose) synthetase during nerve growth factor-promoted neurite outgrowth in rat pheochromocytoma PC12 cells.
Pheochromocytoma
Nerve growth factor induces changes in (2'-5')oligo(A) synthetase and 2'-phosphodiesterase activities during differentiation of PC12 pheochromocytoma cells.
Pheochromocytoma
[Evaluation of urinary excretion of free-cortisol in patients with abnormal pituitary-adrenal axes]
phospholipase a2 deficiency
Disorders of phospholipids, sphingolipids and fatty acids biosynthesis: toward a new category of inherited metabolic diseases.
Pick Disease of the Brain
Neuropathology and pathogenesis of extrapyramidal movement disorders: a critical update-I. Hypokinetic-rigid movement disorders.
Picornaviridae Infections
Constitutive expression of (2'-5') oligo A synthetase confers resistance to picornavirus infection.
Pityriasis Rosea
[Serum interferon level and (2'-5')-oligo(A) synthetase activity in pityriasis rosea, basalioma, melanoma and molluscum contagiosum]
Plague
The Yersinia pestis siderophore, yersiniabactin, and the ZnuABC system both contribute to zinc acquisition and the development of lethal septicaemic plague in mice.
Plasmacytoma
Deoxyribonucleic acid synthesis. I. Effect of in vivo cyclophosphamide treatment on the in vitro activity of the deoxyribonucleic acid synthetase system of sensitive and resistant plasmacytomas.
Plasmacytoma
Pharmaceutical inhibition of glycogen synthetase kinase-3? reduces multiple myeloma-induced bone disease in a novel murine plasmacytoma xenograft model.
Pleurisy
Peroxynitrite-mediated DNA strand breakage activates poly (ADP-ribose) synthetase and causes cellular energy depletion in carrageenan-induced pleurisy.
Pleurisy
Regulation of prostaglandin production by inhibition of poly (ADP-ribose) synthase in carrageenan-induced pleurisy.
Pleurisy
Role of peroxynitrite and poly (ADP-ribose) synthetase on cellular energy depletion in carrageenan-induced pleurisy.
Pneumonia
Clinical characteristics of interstitial lung diseases positive to different anti-synthetase antibodies.
Pneumonia
Clinical significance of radiological patterns of HRCT and their association with macrophage activation in dermatomyositis.
Pneumonia
Inflammatory myopathy, bronchiolitis obliterans/organizing pneumonia, and anti-Jo-1 antibodies--an interesting association.
Pneumonia
Structural characterization of a new N-substituted pantothenamide bound to pantothenate kinases from Klebsiella pneumonia and Staphylococcus aureus.
Polycystic Ovary Syndrome
Polymorphism of glycogen synthetase gene in polycystic ovary syndrome.
Polycystic Ovary Syndrome
[Association study between a polymorphism of aldosterone synthetase gene and the pathogenesis of polycystic ovary syndrome]
Polymyositis
A case of anti-aminoacyl tRNA synthetase (ARS) antibody-positive polymyositis (PM)/dermatomyositis (DM)-associated interstitial pneumonia (IP) successfully controlled with bosentan therapy.
Polymyositis
A case of polymyositis with anti-histidyl-t-RNA synthetase (Jo-1) antibody syndrome following extensive vinyl chloride exposure.
Polymyositis
Acute respiratory distress syndrome secondary to antisynthetase syndrome is reversible with tacrolimus.
Polymyositis
Clinical significance and new detection system of autoantibodies in myositis with interstitial lung disease.
Polymyositis
Correlation of Antisynthetase Antibody Levels with Disease Course in a Patient with Interstitial Lung Disease and Elevated Muscle Enzymes.
Polymyositis
Genome-wide association study identifies HLA 8.1 ancestral haplotype alleles as major genetic risk factors for myositis phenotypes.
Polymyositis
HLA-DRB1*0101/*0405 is associated with susceptibility to Anti-MDA5 antibody-positive dermatomyositis in the Japanese population.
Polymyositis
Juvenile polymyositis associated with anti-OJ (anti-isoleucyl-tRNA synthetase) autoantibody in a 13-year-old girl.
Polymyositis
Nivolumab-induced anti-aminoacyl-tRNA synthetase antibody-positive polymyositis complicated by interstitial pneumonia in a patient with lung adenocarcinoma.
Polymyositis
Polymyositis, pulmonary fibrosis and autoantibodies to aminoacyl-tRNA synthetase enzymes.
Polymyositis
Reliability and clinical utility of Enzyme-linked immunosorbent assay for detection of anti-aminoacyl-tRNA synthetase antibody.
Polymyositis
Rituximab in refractory idiopathic inflammatory myopathies and antisynthetase syndrome: personal experience and review of the literature.
Polymyositis
Wide cross-species aminoacyl-tRNA synthetase replacement in vivo: yeast cytoplasmic alanine enzyme replaced by human polymyositis serum antigen.
Porcine Reproductive and Respiratory Syndrome
Nucleic Acid Immunity and DNA Damage Response: New Friends and Old Foes.
Porcine Reproductive and Respiratory Syndrome
Porcine 2', 5'-oligoadenylate synthetase 2 inhibits porcine reproductive and respiratory syndrome virus replication in vitro.
Porphyria Cutanea Tarda
Hepatic -aminolaevulinic acid synthetase activity in porphyria cutanea tarda.
Porphyria Cutanea Tarda
Red blood cell rhodanese: its possible role in modulating delta-aminolaevulinate synthetase activity in mammals.
Porphyria, Acute Intermittent
Effect of lead on hepatic delta-aminolaevulinic acid synthetase activity in the rat: a model for drug sensitivity in intermittent acute porphyria.
Porphyria, Acute Intermittent
R173W Mutation of Hydroxymethylbilane Synthetase Is Associated With Acute Intermittent Porphyria Complicated With Rhabdomyolysis: The First Report.
Porphyria, Acute Intermittent
Red blood cell rhodanese: its possible role in modulating delta-aminolaevulinate synthetase activity in mammals.
Porphyria, Erythropoietic
-aminolevulinic acid synthetase activity in human plasma: relation to erythropoiesis and evidence of induction in erythropoietic porphyria.
Porphyria, Erythropoietic
Congenital erythropoietic porphyria: dilemmas in present day management.
Porphyria, Erythropoietic
Correction of congenital erythropoietic porphyria by bone marrow transplantation.
Porphyria, Variegate
Red blood cell rhodanese: its possible role in modulating delta-aminolaevulinate synthetase activity in mammals.
Porphyrias
Effect of ethanol on liver delta-aminolaevulinate synthetase activity and urinary porphyrin excretion in symptomatic porphyria.
Porphyrias
Increased hepatic delta-aminolaevulinic acid synthetase in ethionine-induced porphyria in the rat.
Porphyrias
R173W Mutation of Hydroxymethylbilane Synthetase Is Associated With Acute Intermittent Porphyria Complicated With Rhabdomyolysis: The First Report.
Porphyrias
Red blood cell rhodanese: its possible role in modulating delta-aminolaevulinate synthetase activity in mammals.
Porphyrias
The influence of actinomycin D on the activity of delta-aminolaevulinic acid synthetase and dehydratase in the liver of mice and rats treated by griseofulvin.
Porphyrias, Hepatic
Polychlorinated biphenyls as inducers of hepatic porphyria in Japanese quail, with special reference to -aminolevulinic acid synthetase activity, fluorescence, and residues in the liver.
Pre-Eclampsia
Trial of prophylactic administration of TXA2 synthetase inhibitor, ozagrel hydrochloride, for preeclampsia.
Pre-Eclampsia
[Mast cells as a source of nitric oxide in the human placenta--morphometric analysis in preeclampsia complicated pregnancy]
Precursor Cell Lymphoblastic Leukemia-Lymphoma
[Study of the correlation between the expression level of asparagine synthetase and the outcome of children with acute lymphocytic leukemia]
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
Cytidine triphosphate (CTP) synthetase activity during cell cycle progression in normal and malignant T-lymphocytic cells.
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
[Asparagine synthetase activity in pediatric acute lymphoblastic leukemia]
Pregnancy Complications
A novel mouse model for genetic variation in 10-formyltetrahydrofolate synthetase exhibits disturbed purine synthesis with impacts on pregnancy and embryonic development.
Pregnancy Complications
Low Dietary Folate Interacts with MTHFD1 Synthetase Deficiency in Mice, a Model for the R653Q Variant, to Increase Incidence of Developmental Delays and Defects.
Primary Ovarian Insufficiency
Acyl-CoA synthetase long-chain family member 6 is associated with premature ovarian failure.
Progeria
Phenylalanyl synthetase function in cultured fibroblasts from subjects with progeria.
Propionic Acidemia
Carglumic acid: an additional therapy in the treatment of organic acidurias with hyperammonemia?
Propionic Acidemia
Pilot use of the early motor repertoire in infants with inborn errors of metabolism: Outcomes in early and middle childhood.
Prostatic Neoplasms
Effects of platelet-activating factor and its differential regulation by androgens and steroid hormones in prostate cancers.
Proteinuria
Increased glomerular thromboxane synthesis as a possible cause of proteinuria in experimental nephrosis.
Proteinuria
Involvement of thromboxane A2, leukotrienes and free radicals in puromycin nephrosis in rats.
Protoporphyria, Erythropoietic
-Aminolevulinic acid synthetase activity in erythroblasts of patients with erythropoietic protoporphyria.
Protoporphyria, Erythropoietic
Decreased haem synthetase activity in blood cells of patients with erythropoietic protoporphyria.
Protoporphyria, Erythropoietic
Hepatic and erythropoietic protoporphyria. Delta-aminolevulinic acid synthetase, fluorescence, and microfluorospectrophotometric study.
Protoporphyria, Erythropoietic
Induction of hepatic aminolevulinate acid synthetase activity by isoflurane in a genetic model for erythropoietic protoporphyria.
Protoporphyria, Erythropoietic
Red blood cell rhodanese: its possible role in modulating delta-aminolaevulinate synthetase activity in mammals.
Pseudorabies
Autonomous Parvoviruses neither Stimulate nor Are Inhibited by the Type I Interferon Response in Human Normal or Cancer Cells.
Psoriasis
Cytokine milieu of atopic dermatitis, as compared to psoriasis, skin prevents induction of innate immune response genes.
Psoriasis
Epigenetic regulation of OAS2 shows disease-specific DNA methylation profiles at individual CpG sites.
Pterygium
Expression of vascular endothelial growth factor and inducible nitric oxide synthase in pterygia.
Pulmonary Alveolar Proteinosis
Deep phenotyping of MARS1 (interstitial lung and liver disease) and LARS1 (infantile liver failure syndrome 1) recessive multisystemic disease using Human Phenotype Ontology annotation: Overlap and differences. Case report and review of literature.
Pulmonary Alveolar Proteinosis
Methionine supplementation for multi-organ dysfunction in MetRS-related pulmonary alveolar proteinosis.
Pulmonary Embolism
Differential expression of 5-HT-related genes in symptomatic pulmonary embolism patients.
Pulmonary Fibrosis
Dermatomyositis and pulmonary fibrosis associated with anti-Jo-1 antibody.
Pulmonary Fibrosis
Polymyositis, pulmonary fibrosis and autoantibodies to aminoacyl-tRNA synthetase enzymes.
purine-nucleoside phosphorylase deficiency
Altered erythrocyte nucleotide patterns are characteristic of inherited disorders of purine or pyrimidine metabolism.
pyruvate kinase deficiency
Heme synthesis in hereditary hemolytic anemias: decreased delta-aminolevulinic acid synthetase in hemoglobin Köln disease.
Rabies
Distribution of rabies virus, interferon and interferon-mediated enzymes in the brains of virus-infected rats.
Radiculopathy
Roles of thromboxane A2 and leukotriene B4 in radicular pain induced by herniated nucleus pulposus.
Rectal Neoplasms
A phase II study of preoperative chemoradiation with tegafur-uracil plus leucovorin for locally advanced rectal cancer with pharmacogenetic analysis.
Reoviridae Infections
Reovirus type 3 synthesizes proteins in interferon-treated HeLa cells without reversing the antiviral state.
Reperfusion Injury
Comparison of the thromboxane synthetase inhibitor dazoxiben and the prostacyclin mimetic iloprost in an animal model of acute ischaemia and reperfusion.
Reperfusion Injury
Development of novel, water-soluble inhibitors of poly (adenosine 5'-diphosphate ribose) synthetase activity for use in shock and ischemia-reperfusion injury.
Reperfusion Injury
Effect of genetic disruption of poly (ADP-ribose) synthetase on delayed production of inflammatory mediators and delayed necrosis during myocardial ischemia-reperfusion injury.
Reperfusion Injury
Inhibition of the activity of poly(ADP ribose) synthetase reduces ischemia-reperfusion injury in the heart and skeletal muscle.
Reperfusion Injury
Inhibitors of poly (ADP-ribose) synthetase reduce renal ischemia-reperfusion injury in the anesthetized rat in vivo.
Reperfusion Injury
Intratracheal poly (ADP) ribose synthetase inhibition ameliorates lung ischemia reperfusion injury.
Reperfusion Injury
Molecular mechanism underlying Akt activation in zinc-induced cardioprotection.
Reperfusion Injury
Myocardial ischemic preconditioning in rodents is dependent on poly (ADP-ribose) synthetase.
Reperfusion Injury
Myocardial protection by PJ34, a novel potent poly (ADP-ribose) synthetase inhibitor.
Reperfusion Injury
Poly (ADP) ribose synthetase inhibition in alveolar macrophages undergoing hypoxia and reoxygenation.
Reperfusion Injury
Poly(adenosine diphosphate-ribose) synthetase inhibitor 3-aminobenzamide alleviates cochlear dysfunction induced by transient ischemia.
Reperfusion Injury
Prevention of myocardial reperfusion injury by poly(ADP-ribose) synthetase inhibitor, 3-aminobenzamide, in cardioplegic solution: in vitro study of isolated rat heart model.
Reperfusion Injury
Protection against myocardial ischemia and reperfusion injury by 3-aminobenzamide, an inhibitor of poly (ADP-ribose) synthetase.
Reperfusion Injury
Role of peroxynitrite and neuronal nitric oxide synthase in the activation of poly(ADP-ribose) synthetase in a murine model of cerebral ischemia-reperfusion.
Reperfusion Injury
Role of poly (ADP) ribose synthetase in lung ischemia-reperfusion injury.
Respiratory Insufficiency
Diagnostic utility of transbronchial lung cryobiopsy: Two cases of anti-aminoacyl-tRNA synthetase syndrome with respiratory failure.
Respiratory Insufficiency
[Interstitial lung disease in patients with connective tissue diseases]
Restless Legs Syndrome
Sequence Variations in Mitochondrial Ferritin: Distribution in Healthy Controls and Different Types of Patients.
Retinal Degeneration
Metabolic consequences of mitochondrial coenzyme A deficiency in patients with PANK2 mutations.
Retinal Degeneration
Neuro-ophthalmologic and electroretinographic findings in pantothenate kinase-associated neurodegeneration (formerly Hallervorden-Spatz syndrome).
Retinal Degeneration
Pantethine treatment is effective in recovering the disease phenotype induced by ketogenic diet in a pantothenate kinase-associated neurodegeneration mouse model.
Retinal Detachment
Distribution of p27(KIP1), cyclin D1, and proliferating cell nuclear antigen after retinal detachment.
Retinitis Pigmentosa
HARP syndrome is allelic with pantothenate kinase-associated neurodegeneration.
Retinitis Pigmentosa
Retinitis pigmentosa in pantothenate kinase-associated neurodegeneration.
Rett Syndrome
Genomic structure of a human holocytochrome c-type synthetase gene in Xp22.3 and mutation analysis in patients with Rett syndrome.
Reye Syndrome
Abnormalities of carbamyl phosphate synthetase and ornithine transcarbamylase in liver of patients with Reye's syndrome.
Reye Syndrome
Letter: Carbamyl phosphate synthetase and ornithine transcarbamylase in liver of Reye's syndrome.
Reye Syndrome
Partial carbamyl phosphate synthetase deficiency, simulating Reye's syndrome, in a 9-year-old girl.
Reye Syndrome
Partial N-acetyl-glutamate synthetase deficiency masquerading as a valproic acid-induced Reye-like syndrome.
Reye Syndrome
Reye's syndrome simulacra in liver of mice after treatment with chemical agents and encephalomyocarditis virus.
Reye Syndrome
Transiently reduced activity of carbamyl phosphate synthetase and ornithine transcarbamylase in liver of children with Reye's syndrome.
Rhabdomyolysis
R173W Mutation of Hydroxymethylbilane Synthetase Is Associated With Acute Intermittent Porphyria Complicated With Rhabdomyolysis: The First Report.
Rheumatic Heart Disease
[Changes in the end part of the ECG ventricular complex under the effect of digitalis preparations and their combination with metabolic preparations]
Rickets
Relationship between polymorphisms in vitamin D metabolism-related genes and the risk of rickets in Han Chinese children.
Sarcoidosis
Oligo-2',5'-adenylate synthetase activity in peripheral blood mononuclear leukocytes in various diseases.
Sarcoidosis
[Investigations of interferon and oligo-2',5'-adenylate systems in endogenous uveitis]
Sarcoidosis, Pulmonary
Oligo-2',5'-adenylate synthetase in pulmonary sarcoidosis and idiopathic pulmonary fibrosis.
Sarcoma
Carbamoyl phosphate synthetase (glutamine-hydrolyzing): increased activity in cancer cells.
Sarcoma
Infection with Moloney murine sarcoma virus inhibits myogenesis and alters the myogenic-associated (2'-5')oligoadenylate synthetase expression and activity.
Sarcoma
Regulatory properties and behavior of activity of carbamoyl phosphate synthetase II (glutamine-hydrolyzing) in normal and proliferating tissues.
Sarcoma
Sheep gene mapping: additional DNA markers included (CASB, CASK, LALBA, IGF-1 and AMH).
Sarcoma
Specific antigrowth effect of interferon on mouse cells transformed by murine sarcoma virus.
Sarcoma 180
Effects of the chiral isomers of erythro- and threo-9-(2-hydroxy-3-nonyl)adenine on purine metabolism in sarcoma 180 cells.
Sarcoma, Avian
Studies of carcinogenesis by avian sarcoma viruses. II. Virus-induced increase in hyaluronic acid synthetase in chicken fibroblasts.
Sarcoma, Kaposi
Hormonal and immunological regulation of 2', 5'-oligoadenylate synthetase activity in human peripheral blood mononuclear cells.
Sarcoma, Myeloid
Identification of a third form of glycogen synthetase in rat chloroma tumors.
Scleroderma, Systemic
Anti-synthetase syndrome positive for anti-isoleucyl-tRNA synthetase antibodies: an unusual case overlapping with systemic sclerosis and Sjogren's syndrome.
Scleroderma, Systemic
Increased expression of 2'5'oligoadenylate synthetase and double-stranded RNA dependent protein kinase messenger RNAs on affected skin of systemic sclerosis patients.
Scleroderma, Systemic
[Association of anti synthetase syndrome and limited systemic sclerosis in a patient: successful treatment with rituximab].
Seizures
Expansion of the QARS deficiency phenotype with report of a family with isolated supratentorial brain abnormalities.
Seizures
Methionine sulfoximine seizures. 8. The dissociation of the convulsant and glutamine synthetase inhibitory effects.
Seizures
Prospective cohort study for identification of underlying genetic causes in neonatal encephalopathy using whole-exome sequencing.
Seizures
[Hepatic glycogen synthetase deficiency or glycogen storage disease-zero. Mild phenotype with partial enzymatic defect]
Seizures
[Metabolic studies on epileptic seizures. The activity of glutaminase and glutamine synthetase and ammonia metabolism before and during cerebral convulsions]
Seizures, Febrile
Systematic review of the role of prostaglandins and their synthetase inhibitors with respect to febrile seizures.
Sepsis
Changes of hepatic sinusoids in experimental septicemia of rats are correlated with the production of nitrogen monoxide. A morphometrical and immunohistochemical study.
Sepsis
Does the activation of poly (ADP-ribose) synthetase mediate tissue injury in the sepsis induced by cecal ligation and puncture?
Sepsis
Does the activation of poly (ADP-ribose) synthetase mediate tissue injury in the sepsis induced by cecal ligation and puncture? Shock 16:137-142, 2001.
Sepsis
Poly (ADP-ribose) synthetase inhibitor has a heart protective effect in a rat model of experimental sepsis.
Sepsis
Protective effect of a novel, potent inhibitor of poly(adenosine 5'-diphosphate-ribose) synthetase in a porcine model of severe bacterial sepsis.
Sepsis
Regulation of rat liver S-adenosylmethionine synthetase during septic shock: role of nitric oxide.
Sepsis
Thromboxane synthetase inhibition and thromboxane receptor blockade preserve pulmonary and circulatory function in a porcine burn sepsis model.
Shock, Septic
Poly (ADP-ribose) synthetase activation mediates pulmonary microvascular and intestinal mucosal dysfunction in endotoxin shock.
Shock, Septic
Protective effect of Y-20811, a long-lasting thromboxane synthetase inhibitor, on endotoxin shock in rabbits.
Silicosis
The Ameliorative Effects of Arctiin and Arctigenin on the Oxidative Injury of Lung Induced by Silica via TLR-4/NLRP3/TGF-? Signaling Pathway.
Sjogren's Syndrome
Anti-synthetase syndrome positive for anti-isoleucyl-tRNA synthetase antibodies: an unusual case overlapping with systemic sclerosis and Sjogren's syndrome.
Skin Diseases
[Results in the use of calcium pantothenate cream in the treatment of various skin diseases in children]
Skin Diseases
[Serum interferon level and (2'-5')-oligo(A) synthetase activity in pityriasis rosea, basalioma, melanoma and molluscum contagiosum]
Skin Diseases
[The therapeutic action of an ointment with a base of hydrocortisone, lactic acid and calcium pantothenate (Lactacyd hydrocortisone) in various dermatoses.]
Small Cell Lung Carcinoma
Overcoming Radiation Resistance by Iron-Platinum Metal Alloy Nanoparticles in Human Copper Transport 1-Overexpressing Cancer Cells via Mitochondrial Disturbance.
Soft Tissue Infections
The clinical trial of streptomycin pantothenate in the treatment of soft tissue infections.
Spinal Cord Compression
Preventive effects of lecithinized superoxide dismutase and methylprednisolone on spinal cord injury in rats: transcriptional regulation of inflammatory and neurotrophic genes.
Spinal Cord Injuries
Peroxynitrite production and activation of poly (adenosine diphosphate-ribose) synthetase in spinal cord injury.
Spinal Cord Injuries
[Beneficial effect of a selective TXA2 synthetase inhibitor, OKY-046, both on thromboxane B2 production and vascular damage after spinal cord injury in rat spinal cord]
Starvation
Aminoacyl-tRNA synthetase gene regulation in Bacillus subtilis: induction, repression and growth-rate regulation.
Starvation
As (and when) you like it: on-demand phospholipid synthesis drives phagophore expansion during autophagy.
Starvation
Ca(2+)-regulated cyclic electron flow supplies ATP for nitrogen starvation-induced lipid biosynthesis in green alga.
Starvation
Characterization of eukaryotic-like kinase activity in Escherichia coli using the gene-protein database.
Starvation
Decreased phosphoribosylpyrophosphate as the basis for decreased purine synthesis during amino acid starvation of human lymphoblasts.
Starvation
Dynamics of liver glycogen: the topochemistry of glycogen synthesis, glycogen content and glycogenolysis under the experimental conditions of glycogen accumulation and depletion.
Starvation
Effect of extreme amino acid starvation on the protein synthetic machinery of CHO cells.
Starvation
Effect of starvation and insulin-induced hypoglycemia on oxidative stress scavenger system and electron transport chain complexes from rat brain, liver, and kidney.
Starvation
Effect of starvation on tRNA synthesis, amino acid pool, tRNA charging levels and aminoacyl-tRNA synthetase activities in the posterior silk gland of Bombyx mori L.
Starvation
Effect of supplemental dietary chromium or nicotinic acid on carbohydrate metabolism during basal, starvation, and refeeding periods in poults.
Starvation
Induction of heritable respiratory deficiency in Saccharomyces by pantothenate starvation.
Starvation
Mutational analysis of the Escherichia coli spoT gene identifies distinct but overlapping regions involved in ppGpp synthesis and degradation.
Starvation
Penicillin binding protein 2 is dispensable in Escherichia coli when ppGpp synthesis is induced.
Starvation
Phosphoribosylpyrophosphate synthetase of Escherichia coli, Identification of a mutant enzyme.
Starvation
Purine synthesis during amino acid starvation of lymphoblasts with HPRT deficiency or PP-ribose-P synthetase overactivity decreases less than in normal cells.
Starvation
Rapid Curtailing of the Stringent Response by Toxin-Antitoxin Module-Encoded mRNases.
Starvation
Regulation of aromatic amino acid biosynthesis in Escherichia coli K-12: control of the aroF-tyrA operon in the absence of repression control.
Starvation
Regulation of beta-Glucan Synthetase Activity by Auxin in Pea Stem Tissue: I. Kinetic Aspects.
Starvation
Regulation of hepatic fatty acid synthetase in the obese-hyperglycemic mutant mouse.
Starvation
Regulation of the synthesis of unsaturated fatty acids by growth temperature in Bacillus subtilis.
Starvation
relA-Independent amino acid starvation response network of Streptococcus pyogenes.
Starvation
SOLUBILIZATION OF MOUSE LIVER GLYCOGEN SYNTHETASE AND PHOSPHORYLASE DURING STARVATION GLYCOGENOLYSIS AND ITS REVERSAL BY CORTISOL.
Starvation
Starvation causes female-to-male sex reversal through lipid metabolism in the teleost fish, medaka (Olyzias latipes).
Starvation
Sterilization by Adaptive Immunity of a Conditionally Persistent Mutant of Mycobacterium tuberculosis.
Starvation
Stringent response governs the oxidative stress resistance and virulence of Francisella tularensis.
Starvation
Temperature-sensitive growth and decreased thermotolerance associated with relA mutations in Escherichia coli.
Starvation
The ECF sigma factor SigT regulates actinorhodin production in response to nitrogen stress in Streptomyces coelicolor.
Starvation
The effects of experimental inflammation on turnover of fatty acid synthetase and levels of fatty acid synthetase messenger RNA in rat liver.
Starvation
The histidyl-tRNA synthetase-related sequence in the eIF-2 alpha protein kinase GCN2 interacts with tRNA and is required for activation in response to starvation for different amino acids.
Starvation
The molecular aetiology of tRNA synthetase depletion: induction of a GCN4 amino acid starvation response despite homeostatic maintenance of charged tRNA levels.
Starvation
The ppGpp synthetase gene (relA) of Streptomyces coelicolor A3(2) plays a conditional role in antibiotic production and morphological differentiation.
Starvation
The role of strigolactones in P deficiency induced transcriptional changes in tomato roots.
Stevens-Johnson Syndrome
Soluble FAS ligand: a discriminating feature between drug-induced skin eruptions and viral exanthemas.
Stomach Neoplasms
Pyrimidine nucleotide synthesis is more extensive in poorly differentiated than in well-differentiated human gastric carcinoma.
Stomach Neoplasms
YARS as an oncogenic protein that promotes gastric cancer progression through activating PI3K-Akt signaling.
Stomach Ulcer
[Effect of 5-[2-(diethylamino)ethyl]amino-5,11- dihydro[1]benzoxepino[3,4-b]pyridine trihydrochloride (KW-5805) on the biosynthesis of rat gastric mucus]
Stroke
Low intakes of carotene, vitamin?B2 , pantothenate and calcium predict cognitive decline among elderly patients with diabetes mellitus: The Japanese Elderly Diabetes Intervention Trial.
Stroke
Melatonin ameliorates neurologic damage and neurophysiologic deficits in experimental models of stroke.
Stroke
Protective effects of 5-iodo-6-amino-1,2-benzopyrone, an inhibitor of poly(ADP-ribose) synthetase against peroxynitrite-induced glial damage and stroke development.
Stuttering
The Case of a Patient with Pantothenate Kinase-Associated Neurodegeneration Presenting with a Prolonged History of Stuttering Speech and a Misdiagnosis of Parkinson's Disease.
Subarachnoid Hemorrhage
Effects of subarachnoid hemorrhage on platelet-derived vasoconstriction of rabbit basilar artery.
Subarachnoid Hemorrhage
Efficacy and toxicity of thromboxane synthetase inhibitor for cerebral vasospasm after subarachnoid hemorrhage.
Subarachnoid Hemorrhage
Thromboxane A2 synthetase inhibitor failed to ameliorate the arterial narrowing during the chronic phase of cerebral vasospasm.
Supranuclear Palsy, Progressive
Neuropareidolia: diagnostic clues apropos of visual illusions.
Synucleinopathies
Neuropathology and pathogenesis of extrapyramidal movement disorders: a critical update-I. Hypokinetic-rigid movement disorders.
Synucleinopathies
Pantothenate kinase-associated neurodegeneration is not a synucleinopathy.
Tardive Dyskinesia
Severe tongue protrusion dystonia: clinical syndromes and possible treatment.
Tardive Dyskinesia
Tongue Protrusion Dystonia in Pantothenate Kinase-Associated Neurodegeneration.
Tauopathies
Neuropathology and pathogenesis of extrapyramidal movement disorders: a critical update-I. Hypokinetic-rigid movement disorders.
Telangiectasis
Dermatomyositis: an association of gingival telangiectases and anti Jo-1 antibody in the adult.
Tetanus
Postimmunization activity of oligoadenylate synthetase in peripheral blood lymphocytes from healthy individuals.
Thalassemia
First report of co-morbidity of pantothenate kinase-associated neurodegeneration and three types of chronic hemolytic anemias.
Thromboembolism
Effect of thromboxane synthetase inhibitors (OKY-046, OKY-1580) on experimentally induced air embolism in anesthetized dogs.
Thrombosis
Arachidonic acid metabolites, ADP and thrombin modulate occlusive thrombus formation over extensive arterial injury in the rat.
Thrombosis
Dual inhibition of thromboxane A2 synthesis and thromboxane A2/prostaglandin endoperoxide receptors by ridogrel: anti-thrombotic effect in vivo in rat mesenteric arteries.
Thrombosis
Effects of a thromboxane A2-receptor antagonist, a thromboxane synthetase inhibitor and aspirin on prostaglandin I2 production in endothelium-intact and -injured aorta of guinea pigs.
Thrombosis
Endogenous and exogenous nitric oxide protect against intracoronary thrombosis and reocclusion after thrombolysis.
Thrombosis
Photochemically induced thrombosis of the rat coronary artery and functional evaluation of thrombus formation by occurrence of ventricular arrhythmias. Effects of acetylsalicylic acid and a thromboxane A2 synthetase inhibitor of thrombus formation.
Thrombosis
The role of thromboxane (TX) A2 in rabbit arterial thrombosis induced by endothelial damage.
Thyroid Diseases
Correlation between HLA-DR expression and level of poly(ADP-ribose) synthetase in human thyroid carcinoma cells.
Thyroid Neoplasms
Analysis of 2'5' oligo (A) synthetase in patients with advanced thyroid carcinoma.
Thyroid Neoplasms
Correlation between HLA-DR expression and level of poly(ADP-ribose) synthetase in human thyroid carcinoma cells.
Thyroid Neoplasms
Decreased expression of TNFRSF12A in thyroid gland cancer predicts poor prognosis: A study based on TCGA data.
Tourette Syndrome
Pantothenate kinase-associated neurodegeneration mimicking Tourette syndrome: a case report and review of the literature.
Tremor
Novel PANK2 gene mutations in korean patient with pantothenate kinase-associated neurodegeneration presenting unilateral dystonic tremor.
Tremor
Pantothenate kinase-associated neurodegeneration initially presenting as postural tremor alone in a Japanese family with homozygous N245S substitutions in the pantothenate kinase gene.
Tremor
Partial deficit of pantothenate kinase 2 catalytic activity in a case of tremor-predominant neurodegeneration with brain iron accumulation.
Tuberculosis
5-tert-Butyl-N-pyrazol-4-yl-4,5,6,7-tetrahydrobenzo[d]isoxazole-3-carboxamide Derivatives as Novel Potent Inhibitors of Mycobacterium tuberculosis Pantothenate Synthetase: Initiating a Quest for New Antitubercular Drugs.
Tuberculosis
A comparison of the dynamics of pantothenate synthetase from M. tuberculosis and E. coli: Computational studies.
Tuberculosis
A discovery of novel Mycobacterium tuberculosis pantothenate synthetase inhibitors based on the molecular mechanism of actinomycin D inhibition.
Tuberculosis
A eubacterial Mycobacterium tuberculosis tRNA synthetase is eukaryote-like and resistant to a eubacterial-specific antisynthetase drug.
Tuberculosis
A Fragment-Based Approach to Probing Adenosine Recognition Sites by Using Dynamic Combinatorial Chemistry.
Tuberculosis
A high-throughput screen against pantothenate synthetase (PanC) identifies 3-biphenyl-4-cyanopyrrole-2-carboxylic acids as a new class of inhibitor with activity against Mycobacterium tuberculosis.
Tuberculosis
A novel mycolic acid cyclopropane synthetase is required for cording, persistence, and virulence of Mycobacterium tuberculosis.
Tuberculosis
A pantothenate auxotroph of Mycobacterium tuberculosis is highly attenuated and protects mice against tuberculosis.
Tuberculosis
Active site residues in Mycobacterium tuberculosis pantothenate synthetase required in the formation and stabilization of the adenylate intermediate.
Tuberculosis
Alanine mutation of the catalytic sites of Pantothenate Synthetase causes distinct conformational changes in the ATP binding region.
Tuberculosis
Application of Fragment Growing and Fragment Linking to the Discovery of Inhibitors of Mycobacterium tuberculosis Pantothenate Synthetase.
Tuberculosis
Attenuation of Mycobacterium tuberculosis functionally disrupted in a fatty acyl-coenzyme A synthetase gene fadD5.
Tuberculosis
Binding of pyrazole-based inhibitors to Mycobacterium tuberculosis pantothenate synthetase: docking and MM-GB(PB)SA analysis.
Tuberculosis
Chemoinformatic identification of novel inhibitors against Mycobacterium tuberculosis L-aspartate ?-decarboxylase.
Tuberculosis
Crystal Structure of the Pantothenate Synthetase from Mycobacterium tuberculosis, Snapshots of the Enzyme in Action(,).
Tuberculosis
Crystal structures of a pantothenate synthetase from M. tuberculosis and its complexes with substrates and a reaction intermediate.
Tuberculosis
Design of Novel Mycobacterium tuberculosis Pantothenate Synthetase Inhibitors: Virtual Screening, Synthesis and In Vitro Biological Activities.
Tuberculosis
Design, synthesis and biological evaluation of imidazo[2,1-b]thiazole and benzo[d]imidazo[2,1-b]thiazole derivatives as Mycobacterium tuberculosis pantothenate synthetase inhibitors.
Tuberculosis
Development of 3-phenyl-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridine derivatives as novel Mycobacterium tuberculosis pantothenate synthetase inhibitors.
Tuberculosis
Development of novel tetrahydrothieno[2,3-c]pyridine-3-carboxamide based Mycobacterium tuberculosis pantothenate synthetase inhibitors: Molecular hybridization from known antimycobacterial leads.
Tuberculosis
Different ways to transport ammonia in human and Mycobacterium tuberculosis NAD+ synthetases.
Tuberculosis
Essential roles for Mycobacterium tuberculosis Rel beyond the production of (p)ppGpp.
Tuberculosis
Essentiality and functional analysis of type I and type III pantothenate kinases of Mycobacterium tuberculosis.
Tuberculosis
Extended safety and efficacy studies of a live attenuated double leucine and pantothenate auxotroph of Mycobacterium tuberculosis as a vaccine candidate.
Tuberculosis
Failure of a Mycobacterium tuberculosis DeltaRD1 DeltapanCD double deletion mutant in a neonatal calf aerosol M. bovis challenge model: Comparisons to responses elicited by M. bovis bacille Calmette Guerin.
Tuberculosis
Heat-stable stimulating factor for fatty acid synthetase from Mycobacterium tuberculosis H37Rv.
Tuberculosis
Heterologous expression, purification, and enzymatic activity of Mycobacterium tuberculosis NAD(+) synthetase.
Tuberculosis
High throughput screening against pantothenate synthetase identifies amide inhibitors against Mycobacterium tuberculosis and Staphylococcus aureus.
Tuberculosis
How pantothenol intervenes in Coenzyme-A biosynthesis of Mycobacterium tuberculosis.
Tuberculosis
Identification and development of 2-methylimidazo[1,2-a]pyridine-3-carboxamides as Mycobacterium tuberculosis pantothenate synthetase inhibitors.
Tuberculosis
Identification of a Mycobacterium tuberculosis gene cluster encoding the biosynthetic enzymes for assembly of the virulence-conferring siderophore mycobactin.
Tuberculosis
Inhibition of Mycobacterium tuberculosis pantothenate synthetase by analogues of the reaction intermediate.
Tuberculosis
Inositol-1-phosphate synthetase mRNA as a new target for antisense inhibition of Mycobacterium tuberculosis.
Tuberculosis
Integrated biophysical approach to fragment screening and validation for fragment-based lead discovery.
Tuberculosis
Location and conformation of pantothenate and its derivatives in Mycobacterium tuberculosis pantothenate kinase: insights into enzyme action.
Tuberculosis
Long-term protection against tuberculosis following vaccination with a severely attenuated double lysine and pantothenate auxotroph of Mycobacterium tuberculosis.
Tuberculosis
M. tuberculosis pantothenate kinase: dual substrate specificity and unusual changes in ligand locations.
Tuberculosis
Modular approach to triazole-linked 1,6-?-d-oligomannosides to the discovery of inhibitors of Mycobacterium tuberculosis cell wall synthetase.
Tuberculosis
Mycobacterium tuberculosis DeltaRD1 DeltapanCD: a safe and limited replicating mutant strain that protects immunocompetent and immunocompromised mice against experimental tuberculosis.
Tuberculosis
Mycobacterium tuberculosis PanD Structure-Function Analysis and Identification of a Potent Pyrazinoic Acid-Derived Enzyme Inhibitor.
Tuberculosis
Mycobacterium tuberculosis pantothenate kinase: possible changes in location of ligands during enzyme action.
Tuberculosis
Mycobacterium tuberculosis Phe-tRNA synthetase: structural insights into tRNA recognition and aminoacylation.
Tuberculosis
Optimization of Inhibitors of Mycobacterium tuberculosis Pantothenate Synthetase Based on Group Efficiency Analysis.
Tuberculosis
Optimization of the interligand overhauser effect for fragment linking: application to inhibitor discovery against Mycobacterium tuberculosis pantothenate synthetase.
Tuberculosis
Pantothenate and pantetheine antagonize the antitubercular activity of pyrazinamide.
Tuberculosis
Pantothenic acid biosynthesis in the parasite Toxoplasma gondii: a target for chemotherapy.
Tuberculosis
Protection elicited by a double leucine and pantothenate auxotroph of Mycobacterium tuberculosis in guinea pigs.
Tuberculosis
Pyrazinamide inhibits the eukaryotic-like fatty acid synthetase I (FASI) of Mycobacterium tuberculosis.
Tuberculosis
Quinolidene based monocarbonyl curcumin analogues as promising antimycobacterial agents: Synthesis and molecular docking study.
Tuberculosis
Rational Design of Biosafety Level 2-Approved, Multidrug-Resistant Strains of Mycobacterium tuberculosis through Nutrient Auxotrophy.
Tuberculosis
Reconstitution of Protein Translation of Mycobacterium Reveals Functional Conservation and Divergence with the Gram-Negative Bacterium Escherichia coli.
Tuberculosis
Restoration of mycolate synthetase activity in Mycobacterium tuberculosis exposed to isoniazid.
Tuberculosis
Site of inhibitory action of isoniazid in the synthesis of mycolic acids in Mycobacterium tuberculosis.
Tuberculosis
Steady-state and pre-steady-state kinetic analysis of Mycobacterium tuberculosis pantothenate synthetase.
Tuberculosis
Structural and biochemical characterization of compounds inhibiting Mycobacterium tuberculosis pantothenate kinase.
Tuberculosis
Structure-guided design of thiazolidine derivatives as Mycobacterium tuberculosis pantothenate synthetase inhibitors.
Tuberculosis
Susceptibility and mode of binding of the Mycobacterium tuberculosis cysteinyl transferase mycothiol ligase to tRNA synthetase inhibitors.
Tuberculosis
Synthesis, in vitro antimycobacterial evaluation and docking studies of some new 5,6,7,8-tetrahydropyrido[4',3':4,5]thieno[2,3-d]pyrimidin-4(3H)-one schiff bases.
Tuberculosis
Targeting Mycobacterium tuberculosis CoaBC through Chemical Inhibition of 4'-Phosphopantothenoyl-l-cysteine Synthetase (CoaB) Activity.
Tuberculosis
The crystal structure of the first enzyme in the pantothenate biosynthetic pathway, ketopantoate hydroxymethyltransferase, from M tuberculosis.
Tuberculosis
The MM2QM tool for combining docking, molecular dynamics, molecular mechanics, and quantum mechanics.
Tuberculosis
The Mycobacterium tuberculosis cmaA2 gene encodes a mycolic acid trans-cyclopropane synthetase.
Tuberculosis
Validation of CoaBC as a Bactericidal Target in the Coenzyme A Pathway of Mycobacterium tuberculosis.
Tuberculosis
[Acetylation processes during the treatment of tuberculosis with antibacterial preparations and calcium pantothenate.]
Tuberculosis
[Advantages of streptomycin pantothenate in tuberculosis in subjects with an intolerance or resistance to streptomycin.]
Tuberculosis
[Calcium pantothenate in clinical tuberculosis in the presence of side effects of streptomycin.]
Tuberculosis
[Clinico-experimental studies on dihydrostreptomycin pantothenate in tuberculosis.]
Tuberculosis
[Experience with the use of dihydrostreptomycin pantothenate in the treatment of tuberculosis.]
Tuberculosis
[On the tolerance for a combination of dihydrostreptomycin pantothenate and dihydrostreptomycin sulfate in the therapy of tuberculosis with particular reference to the therapy of tuberculous meningitis.]
Tuberculosis
[Role of calcium pantothenate in vitamin B requirement of children with tuberculosis]
Tuberculosis
[THE EFFECT OF CALCIUM PANTOTHENATE ON THE EFFECTIVENESS OF ANTIBACTERIAL THERAPY OF EXPERIMENTAL TUBERCULOSIS.]
Tuberculosis
[The treatment of tuberculosis with PAS-streptomycin pantothenate in venous perfusion.]
Tuberculosis
[Value of dihydrostreptomycin pantothenate in the prevention of accidents during intensive treatment of tuberculosis.]
Tuberculosis
[Viomycin pantothenate in therapy-resistant primary tuberculosis in small children.]
Tuberculosis, Meningeal
[On the tolerance for a combination of dihydrostreptomycin pantothenate and dihydrostreptomycin sulfate in the therapy of tuberculosis with particular reference to the therapy of tuberculous meningitis.]
Tuberculosis, Pulmonary
The pantothenate of streptomycin in the treatment of pulmonary tuberculosis.
Tuberculosis, Pulmonary
[Combined treatment of pulmonary tuberculosis with DSM pantothenate, INH and PAS in continuous infusion.]
Tuberculosis, Pulmonary
[Dihydrostreptomycin pantothenate & its tolerance in the treatment of pulmonary tuberculosis.]
Tuberculosis, Pulmonary
[The effect of combined streptomycin pantothenate and INH therapy on the otovestibular system in chronic pulmonary tuberculosis patients.]
Tuberculosis, Pulmonary
[Value & tolerance of dihydrostreptomycin pantothenate in the treatment of pulmonary tuberculosis.]
Tuberculosis, Pulmonary
[Viomycin and viomycin pantothenate with reduced toxicity in therapy of pulmonary tuberculosis.]
unspecific monooxygenase deficiency
Disorders of phospholipids, sphingolipids and fatty acids biosynthesis: toward a new category of inherited metabolic diseases.
Urea Cycle Disorders, Inborn
Alteration of urinary carnitine profile induced by benzoate administration.
Urea Cycle Disorders, Inborn
The allopurinol load test lacks specificity for primary urea cycle defects but may indicate unrecognized mitochondrial disease.
Urinary Bladder Neoplasms
Identification of bladder cancer antigens recognized by IgG antibodies of a patient with metastatic bladder cancer.
Urinary Bladder Neoplasms
[The effect of different types of recombinant interferon on the induction of 2,5-oligoadenylate synthetase in natural killers and the tumor cells in bladder cancer patients]
Uterine Cervical Neoplasms
Genetic variations in the SULF1 gene alter the risk of cervical cancer and precancerous lesions.
Uterine Cervical Neoplasms
Poly(ADP-ribose) synthesis in human cervical cancer cell-diagnostic cytological usefulness.
Uterine Cervicitis
An integrative investigation of the therapeutic mechanism of Ainsliaea fragrans Champ. in cervicitis using liquid chromatography tandem mass spectrometry based on a rat plasma metabolomics strategy.
Uveomeningoencephalitic Syndrome
Oligo-2',5'-adenylate synthetase activity in peripheral blood mononuclear leukocytes in various diseases.
Vaccinia
Vaccinia-mediated rescue of encephalomyocarditis virus from the inhibitory effects of interferon.
Vaginal Discharge
Identification of viral infections in pregnancy by assay of (2'-5')-oligo-isoadenylate synthetase.
Vasculitis
Effect of thromboxane synthetase inhibitor on feline infectious peritonitis in cats.
Vasospasm, Intracranial
Beneficial effect of OKY-046, a selective thromboxane A2 synthetase inhibitor, on experimental cerebral vasospasm.
Vasospasm, Intracranial
Effects of thromboxane synthetase inhibitor (RS-5186) on experimentally-induced cerebral vasospasm.
Vasospasm, Intracranial
Efficacy and toxicity of thromboxane synthetase inhibitor for cerebral vasospasm after subarachnoid hemorrhage.
Vasospasm, Intracranial
Thromboxane A2 synthetase inhibitor failed to ameliorate the arterial narrowing during the chronic phase of cerebral vasospasm.
Vesicular Stomatitis
Biochemical analysis of mutants of a macrophage cell line resistant to the growth-inhibitory activity of interferon.
Vesicular Stomatitis
Biologic response (antiviral) to recombinant human interferon alpha 2a as a function of dose and route of administration in healthy volunteers.
Vesicular Stomatitis
Cloning, sequencing, and expression of two murine 2'-5'-oligoadenylate synthetases. Structure-function relationships.
Vesicular Stomatitis
Induction by vasoactive intestinal peptide of interferon alpha/beta synthesis in glial cells but not in neurons.
Vesicular Stomatitis
Induction of an antiviral state by interferon in the absence of elevated levels of 2,5-oligo(A) synthetase and eIF-2 kinase.
Vesicular Stomatitis
Inhibition of mouse fibroblast interferon by gangliosides. Differential effects on biological activity and on induction of (2'--5')oligoadenylate synthetase.
Vesicular Stomatitis
Possible involvement of virus-induced protein kinase in the antiviral state induced with interferon-gamma against Sindbis virus.
Vesicular Stomatitis
Time course of interferon levels, antiviral state, 2',5'-oligoadenylate synthetase and side effects in healthy men.
Vesicular Stomatitis
[Vasoactive intestinal peptide induces 2',5'-oligoadenylate synthetase and antiviral state in cells of HT-29 colonic cancer]
Viremia
Altered tissue distribution of viral replication and T cell spreading is pivotal in the protection against fatal lymphocytic choriomeningitis in mice after neutralization of IFN-alpha/beta.
Virus Diseases
(2'-5') Oligo A synthetase in human polymorphonuclear cells increased activity in interferon treatment and in viral infections.
Virus Diseases
(2'-5') oligo adenylate synthetase activity in leucocytes of patients with inflammatory bowel disease.
Virus Diseases
A phenolic small molecule inhibitor of RNase L prevents cell death from ADAR1 deficiency.
Virus Diseases
Basal and interferon-induced 2',5'-oligoadenylate synthetase in human monocytes, lymphocytes, and peritoneal macrophages.
Virus Diseases
Biologic response (antiviral) to recombinant human interferon alpha 2a as a function of dose and route of administration in healthy volunteers.
Virus Diseases
Common Genetic Variants and Risk for HPV Persistence and Progression to Cervical Cancer.
Virus Diseases
Comparison of (2'-5') oligo-adenylate synthetase and interferon blood-levels in mice early after viral infection.
Virus Diseases
Diagnostic evaluation of 2', 5'-oligoadenylate synthetase activities and antibodies against Epstein-Barr virus and Coxiella burnetii in patients with chronic fatigue syndrome in Japan.
Virus Diseases
Distribution of immunoreactive 2',5'-oligoadenylate synthetase in mouse reproductive organs.
Virus Diseases
Evidence from twins for acquired cellular immune hyperactivity in type 1 diabetes.
Virus Diseases
Functional evolution of the OAS1 viral sensor: Insights from old world primates.
Virus Diseases
Identification of viral infections in pregnancy by assay of (2'-5')-oligo-isoadenylate synthetase.
Virus Diseases
Indomethacin enhances serum 2'5'-oligoadenylate synthetase in patients with hepatitis B and C virus chronic active hepatitis.
Virus Diseases
Induction and measurement of 2',5'-oligoadenylate synthetase in Madin-Darby bovine kidney cells and in cattle.
Virus Diseases
Induction of gene expression by intracellular interferon-gamma: abrogation of the species specificity barrier.
Virus Diseases
Induction of OAS gene family in HIV monocyte infected patients with high and low viral load.
Virus Diseases
Infection of mouse neurones by West Nile virus is modulated by the interferon-inducible 2'-5' oligoadenylate synthetase 1b protein.
Virus Diseases
Interferon cures cells lytically and persistently infected with African swine fever virus in vitro.
Virus Diseases
Interferon stimulates the expression of 2',5'-oligoadenylate synthetase and MHC class I antigens in insulin-producing cells.
Virus Diseases
Lanthionine Synthetase C-Like 2 Modulates Immune Responses to Influenza Virus Infection.
Virus Diseases
Loss of (2'-5')oligoadenylate synthetase activity by production of antisense RNA results in lack of protection by interferon from viral infections.
Virus Diseases
Molecular Mechanisms for the Adaptive Switching Between the OAS/RNase L and OASL/RIG-I Pathways in Birds and Mammals.
Virus Diseases
Murine pancreatic beta TC3 cells show greater 2', 5'-oligoadenylate synthetase (2'5'AS) antiviral enzyme activity and apoptosis following IFN-alpha or poly(I:C) treatment than pancreatic alpha TC3 cells.
Virus Diseases
OAS1 and OAS3 negatively regulate the expression of chemokines and interferon-responsive genes in human macrophages.
Virus Diseases
Polymorphisms in the oligoadenylate synthetase gene cluster and its association with clinical outcomes of dengue virus infection.
Virus Diseases
RNase L restricts the mobility of engineered retrotransposons in cultured human cells.
Virus Diseases
Variation of (2'-5') oligo A synthetase level in lymphocytes and granulocytes of patients with viral infections and leukemia.
Virus Diseases
Viral phosphodiesterases that antagonize double-stranded RNA signaling to RNase L by degrading 2-5A.
Virus Diseases
[Early diagnosis of central nervous system (CNS) viral infections in the neonatal period and early infancy]
Vision Disorders
Congenital Visual Impairment and Progressive Microcephaly Due to Lysyl-Transfer Ribonucleic Acid (RNA) Synthetase (KARS) Mutations: The Expanding Phenotype of Aminoacyl-Transfer RNA Synthetase Mutations in Human Disease.
Vitamin A Deficiency
[Retinol-palmitate synthetase and retinol-palmitate hydrolase activity in small intestine mucosa and mucosal cell membranes in vitamin A deficiency and exposure to ionizing radiation]
Vitamin B 12 Deficiency
Effects of the disruption of transmethylation in the central nervous system: an animal model.
Vitamin B 12 Deficiency
[Effect of pantothenate on indices related to cobalamin metabolism in vitamin B 12 deficiency]
Vitamin B 6 Deficiency
Hydrogen sulphide production by yeast under conditions of methionine, pantothenate or vitamin B6 deficiency.
Vocal Cord Dysfunction
Pantothenate kinase-associated neurodegeneration causing paradoxical vocal fold motion.
West Nile Fever
Infection of mouse neurones by West Nile virus is modulated by the interferon-inducible 2'-5' oligoadenylate synthetase 1b protein.
Whooping Cough
[Treatment of whooping cough with mixture of streptomycin pantothenate and dihydrostreptomycin.]
Yellow Fever
Postimmunization activity of oligoadenylate synthetase in peripheral blood lymphocytes from healthy individuals.
Zellweger Syndrome
Beta-oxidation of very-long-chain fatty acids and their coenzyme A derivatives by human skin fibroblasts.
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