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Information on EC 6.2.1.15 - arachidonate-CoA ligase

for references in articles please use BRENDA:EC6.2.1.15

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IUBMB Comments

Not identical with EC 6.2.1.3 long-chain-fatty-acid—CoA ligase. Icosa-8,11,14-trienoate, but not the other long-chain fatty acids, can act in place of arachidonate.

The enzyme appears in viruses and cellular organisms
  • 6.2.1.15
  • ferroptosis
  • arachidonic
  • acsls
  • erastin
  • ferroptosis-related
  • acid-coa
  • triacsin
  • ferrostatin-1
  • slc7a11
  • alport
  • col4a5
  • erastin-induced
  • liproxstatin-1

Synonyms
acsl4, facl4, arachidonoyl-coa synthetase, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
ATP + arachidonate + CoA = AMP + diphosphate + arachidonoyl-CoA
show the reaction diagram
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