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Information on EC 6.1.1.7 - alanine-tRNA ligase and Organism(s) Drosophila melanogaster and UniProt Accession Q9VRJ1

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This record set is specific for:
Drosophila melanogaster
UNIPROT: Q9VRJ1 not found.
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The taxonomic range for the selected organisms is: Drosophila melanogaster
The enzyme appears in selected viruses and cellular organisms
Synonyms
alanyl-trna synthetase, alars, aars2, alanine trna synthetase, ala-trna synthetase, mitochondrial alanyl-trna synthetase, alanyl-transfer rna synthetase, mtalars, alanine-trna ligase, more
SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
Ala-tRNA synthetase
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Alanine transfer RNA synthetase
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Alanine translase
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Alanine tRNA synthetase
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Alanine-transfer RNA ligase
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alanine-tRNA ligase
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Alanyl-transfer ribonucleate synthetase
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Alanyl-transfer ribonucleic acid synthetase
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Alanyl-transfer RNA synthetase
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Alanyl-tRNA synthetase
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Synthase, alanyl-transfer ribonucleate
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Ala-tRNA synthetase
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-
-
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Alanine transfer RNA synthetase
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-
-
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Alanine translase
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-
-
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Alanine tRNA synthetase
-
-
-
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Alanine--tRNA ligase
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-
-
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Alanine-transfer RNA ligase
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-
-
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Alanyl-transfer ribonucleate synthetase
-
-
-
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Alanyl-transfer ribonucleic acid synthetase
-
-
-
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Alanyl-transfer RNA synthetase
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-
-
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Alanyl-tRNA synthetase
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-
-
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AlaRS
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-
-
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Synthase, alanyl-transfer ribonucleate
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-
-
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REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
esterification
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-
-
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Aminoacylation
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-
-
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PATHWAY SOURCE
PATHWAYS
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SYSTEMATIC NAME
IUBMB Comments
L-alanine:tRNAAla ligase (AMP-forming)
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CAS REGISTRY NUMBER
COMMENTARY hide
9031-71-4
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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
ATP + L-alanine + tRNAAla
AMP + diphosphate + L-alanyl-tRNAAla
show the reaction diagram
-
-
?
NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
ATP + L-alanine + tRNAAla
AMP + diphosphate + L-alanyl-tRNAAla
show the reaction diagram
-
-
?
COFACTOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
gene alaS is nuclear-encoded, mitochondrial isozyme
SwissProt
Manually annotated by BRENDA team
LOCALIZATION
ORGANISM
UNIPROT
COMMENTARY hide
GeneOntology No.
LITERATURE
SOURCE
UNIPROT
ENTRY NAME
ORGANISM
NO. OF AA
NO. OF TRANSM. HELICES
MOLECULAR WEIGHT[Da]
SOURCE
SEQUENCE
LOCALIZATION PREDICTION?
SYAM_DROME
1012
0
113104
Swiss-Prot
Mitochondrion (Reliability: 3)
CLONED (Commentary)
ORGANISM
UNIPROT
LITERATURE
gene alaS, DNA sequence determination and analysis, phylogenetic origin
deletion mutants with reduced aminoacylation efficiency, expressed in Escherichia coli strain BL21
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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Chihade, J.W.; Brown, J.R.; Schimmel, P.R.; De Pouplana, L.R.
Origin of mitochondria in relation to evolutionary history of eukaryotic alanyl-tRNA synthetase
Proc. Natl. Acad. Sci. USA
97
12153-12157
2000
Dictyostelium discoideum (Q54Y20), Giardia intestinalis (Q9U022), Drosophila melanogaster (Q9VRJ1)
Manually annotated by BRENDA team
Lovato, M.A.; Swairjo, M.A.; Schimmel, P.
Positional recognition of a tRNA determinant dependent on a peptide insertion
Mol. Cell
13
843-851
2004
Drosophila melanogaster
Manually annotated by BRENDA team