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Information on EC 5.6.1.8 - myosin ATPase

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IUBMB Comments
Proteins of the contractile apparatus of muscle and nonmuscle cells; myosin molecule consists of two heavy chains (about 200 kDa) and two pairs of light chains (15--27 kDa). The head region of the heavy chain contains actin- and ATP-binding sites. ATP hydrolysis provides energy for actomyosin contraction.
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The enzyme appears in viruses and cellular organisms
Reaction Schemes
+
+
myosin bound to actin filament at position n
=
+
+
myosin bound to actin filament at position n+1
Synonyms
actin activated myosin ATPase, actin-stimulated myosin ATPase, actomyosin, actomyosin 1b ATPase, actomyosin ATPase, actomyosin-ATPase, heavy meromyosin, heavy meromyosin ATPase, HMM, HMM ATPase, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
ATP + H2O + myosin bound to actin filament at position n = ADP + phosphate + myosin bound to actin filament at position n+1
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