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Information on EC 5.5.1.30 - labda-7,13-dienyl diphosphate synthase and Organism(s) Streptomyces clavuligerus and UniProt Accession D5SJ87

for references in articles please use BRENDA:EC5.5.1.30
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IUBMB Comments
Isolated from the bacterium Streptomyces clavuligerus.
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This record set is specific for:
Streptomyces clavuligerus
UNIPROT: D5SJ87
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The taxonomic range for the selected organisms is: Streptomyces clavuligerus
The expected taxonomic range for this enzyme is: Streptomyces clavuligerus
Synonyms
sclav_p0490, more
SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
prenyltransferase and squalene oxidase repeat protein
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SCLAV_p0490
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SYSTEMATIC NAME
IUBMB Comments
(13E)-labda-7,13-dien-15-yl-diphosphate lyase (ring-opening)
Isolated from the bacterium Streptomyces clavuligerus.
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
geranylgeranyl diphosphate
(13E)-labda-7,13-dien-15-yl diphosphate
show the reaction diagram
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?
METALS and IONS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
Mg2+
assay in presence of
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
GENERAL INFORMATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
physiological function
SCLAV_p0490 catalyzes the generation of labda-8(17),13-dienyl diphosphate by the release of a proton at H-7 in the C8-carbonium ion of (+)-copalyl diphosphate
UNIPROT
ENTRY NAME
ORGANISM
NO. OF AA
NO. OF TRANSM. HELICES
MOLECULAR WEIGHT[Da]
SOURCE
SEQUENCE
LOCALIZATION PREDICTION?
LADIS_STRCL
545
0
58120
Swiss-Prot
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CLONED (Commentary)
ORGANISM
UNIPROT
LITERATURE
expression in Escherichia coli
REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Yamada, Y.; Komatsu, M.; Ikeda, H.
Chemical diversity of labdane-type bicyclic diterpene biosynthesis in Actinomycetales microorganisms
J. Antibiot.
69
515-523
2016
Streptomyces clavuligerus (D5SJ87), Streptomyces clavuligerus, Streptomyces clavuligerus ATCC 27064 (D5SJ87)
Manually annotated by BRENDA team