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Synonyms
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Haur_2145
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geranylgeranyl diphosphate = (+)-kolavenyl diphosphate
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(+)-kolavenyl-diphosphate lyase (ring-opening)
Isolated from the bacterium Herpetosiphon aurantiacus.
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geranylgeranyl diphosphate
(+)-kolavenyl diphosphate
additional information
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geranylgeranyl diphosphate
(+)-kolavenyl diphosphate
Substrates: -
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geranylgeranyl diphosphate
(+)-kolavenyl diphosphate
Substrates: -
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additional information
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Substrates: no substrate: farnesyl diphosphate
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additional information
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Substrates: no substrate: farnesyl diphosphate
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additional information
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Substrates: no substrate: farnesyl diphosphate
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additional information
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Substrates: no substrate: farnesyl diphosphate
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geranylgeranyl diphosphate
(+)-kolavenyl diphosphate
geranylgeranyl diphosphate
(+)-kolavenyl diphosphate
Substrates: -
?
geranylgeranyl diphosphate
(+)-kolavenyl diphosphate
Substrates: -
?
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UniProt
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UniProt
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Highest Expressing Human Cell Lines
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Cell Line Links
Gene Links
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physiological function
enzyme is a class II diterpene cyclase responsible for the conversion of geranylgeranyl diphosphate into kolavenyl diphosphate. Subsequently, gene product Haur_2146, homologous to Rv3378c, synthesizes (+)-kolavelool through the nucleophilic addition of a water molecule to the incipient cation formed after the diphosphate moiety is released
physiological function
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enzyme is a class II diterpene cyclase responsible for the conversion of geranylgeranyl diphosphate into kolavenyl diphosphate. Subsequently, gene product Haur_2146, homologous to Rv3378c, synthesizes (+)-kolavelool through the nucleophilic addition of a water molecule to the incipient cation formed after the diphosphate moiety is released
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TPS5_VITAC
800
0
91815
Swiss-Prot
other Location (Reliability: 3 )
KVDS_HERA2
Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)
521
0
58496
Swiss-Prot
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expression in Escherichia coli
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Nakano, C.; Oshima, M.; Kurashima, N.; Hoshino, T.
Identification of a new diterpene biosynthetic gene cluster that produces O-methylkolavelool in Herpetosiphon aurantiacus
ChemBioChem
16
772-781
2015
Herpetosiphon aurantiacus (A9AWD5), Herpetosiphon aurantiacus, Herpetosiphon aurantiacus DSM 785 (A9AWD5), Herpetosiphon aurantiacus DSM 785
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