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Information on EC 5.5.1.27 - D-galactarolactone cycloisomerase

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IUBMB Comments
The enzyme, characterized from the bacterium Agrobacterium fabrum strain C58, is involved in degradation of D-galacturonate and D-glucuronate. Activity with D-galactaro-1,4-lactone is 4-fold higher than with D-glucaro-1,4-lactone.
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  • 5.5.1.27
  • inappropriate
  • antidiuretic
  • osmolality
  • siadh
  • vasopressin
  • insipidus
  • hyponatremia
  • aldosterone
  • allozyme
  • toad
  • aldhs
  • renin
  • transepithelial
  • diuresis
  • hypertonic
  • hawaiian
  • brattleboro
  • obscura
  • 1.1.1.1
  • subgenus
The expected taxonomic range for this enzyme is: Bacteria, Archaea
Synonyms
galactarolactone cycloisomerase, GCI, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
D-galactaro-1,4-lactone = 5-dehydro-4-deoxy-D-glucarate
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D-glucaro-1,4-lactone = 5-dehydro-4-deoxy-D-glucarate
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